Verfügbarkeit: Chemical Biology of Nucleic Acids

Chemical Biology of Nucleic Acids: Fundamentals and Clinical Applications

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Bibliographische Detailangaben
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Berlin [u.a.] Springer 2014
Schriftenreihe:	RNA Technologies
Schlagworte:	Biowissenschaften Medizin Life sciences Human genetics Medicine Nucleic acids Chemische Biologie RNS Molekulare Medizin Klinische Medizin Biochemie Molekularbiologie Nucleinsäuren Aufsatzsammlung
Online-Zugang:	TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract
Beschreibung:	1 Online-Ressource
ISBN:	9783642544521
DOI:	10.1007/978-3-642-54452-1

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Datensatz im Suchindex

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adam_text	CHEMICAL BIOLOGY OF NUCLEIC ACIDS / : 2014 TABLE OF CONTENTS / INHALTSVERZEICHNIS RNA AS MAJOR COMPONENTS IN CHEMICAL EVOLVABLE SYSTEMS HOW THE EARLY GENETIC CODE WAS ESTABLISHED? - INFERENCE FROM THE ANALYSIS OF EXTANT ANIMAL MITOCHONDRIAL DECODING SYSTEMS ISOMERIZATION OF RNA PHOSPHODIESTER LINKAGES EFFECTS OF IONIC LIQUID AND LIPOSOMES ON THE STRUCTURE, STABILITY AND FUNCTION OF NUCLEIC ACIDS OXIDATIVE DAMAGE ON RNA NUCLEOBASES USE OF FRET TO STUDY DYNAMICS OF DNA REPLICATION DESIGN, CHARACTERIZATION AND APPLICATION OF IMIDAZOPYRIDOPYRIMIDINE:NAPHTHYRIDINE BASE-PAIRING MOTIFS CONSISTING OF FOUR HYDROGEN BONDS CREATION OF UNNATURAL BASE PAIR SYSTEMS TOWARD NEW DNA/RNA BIOTECHNOLOGIES FLEXIBLE NUCLEOBASE ANALOGUES. NOVEL TOOLS FOR EXPLORING THE NUCLEIC ACIDS SEQUENCE SELECTIVE RECOGNITION OF DOUBLE-STRANDED RNA DETERMINING TRANSIENT NUCLEIC ACID STRUCTURES BY NMR DIASTEREOMER-SPECIFIC REPERTOIRE OF 7′R- OR 7′S-ME-CARBA-LOCKED NUCLEIC ACIDS (CLNAS) IN ANTISENSE OLIGO/RNA DUPLEXES AND ENGINEERING OF PHYSICOCHEMICAL AND ENZYMOLOGICAL PROPERTIES CHALLENGES AND OPPORTUNITIES FOR OLIGONUCLEOTIDE-BASED THERAPEUTICS BY ANTISENSE AND RNA INTERFERENCE MECHANISMS PROGRESS IN CHEMICALLY MODIFIED NUCLEIC ACID APTAMERS APTAMERS AS MOLECULAR SMUGGLERS BIOCHEMICAL ASPECTS OF SUBCELLULAR RNA TRANSPORT AND LOCALIZATION SMALL SIZE, BIG IMPACT: BACTERIAL FUNCTIONAL NUCLEIC ACIDS AND THEIR APPLICATIONS TOWARDS DEFINED DNA AND RNA DELIVERY VEHICLES USING NUCLEIC ACID NANOTECHNOLOGY TARGETED EDITING OF THERAPEUTIC GENES USING DNA-BASED TRANSCRIPTIONAL ACTIVATORS: SCOPE AND CHALLENGES INTERACTION OF DNA INTRAMOLECULAR STRUCTURES WITH THEIR COMPLEMENTARY STRANDS: A THERMODYNAMIC APPROACH FOR THE CONTROL OF GENE EXPRESSION SITE DIRECTED SPIN LABELLING OF RNA FOR DISTANCE MEASUREMENTS BY EPR CHEMO-ENZYMATIC STRATEGIES TO MODIFY RNA IN VITRO OR IN LIVING CELLS METAL DEPENDENCE OF LIGAND BINDING AND HEAVY-ATOM DERIVATIZATION OF EVOLUTIONARILY DISTINCT PREQ1 RIBOSWITCHES DNA G-QUADRUPLEXES AND I-MOTIFS IN THERAPEUTICS AND DIAGNOSTICS PEPTIDES TARGETING G-QUADRUPLEX STRUCTURES SYNTHESIS OF SITE-SPECIFICALLY MODIFIED LONG-MER RNAS SYNTHESIS AND EXON-SKIPPING ACTIVITY OF CHEMICALLY-MODIFIED RNAS MRNA AND SNRNA CAP ANALOGS: SYNTHESIS AND APPLICATIONS INNOVATIVE CHEMISTRY FOR SYNTHESIS OF REGULAR RNA, 5’-TRIPHOSPHATE RNA OR 5’-CAPPED RNA. DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT. CHEMICAL BIOLOGY OF NUCLEIC ACIDS / : 2014 ABSTRACT / INHALTSTEXT THIS VOLUME CONTAINS 29 ENGROSSING CHAPTERS CONTRIBUTED BY WORLDWIDE, LEADING RESEARCH GROUPS IN THE FIELD OF CHEMICAL BIOLOGY. TOPICS INCLUDE PRE-BIOLOGY; THE ESTABLISHMENT OF THE GENETIC CODE; ISOMERIZATION OF RNA; DAMAGE OF NUCLEOBASES IN RNA; THE DYNAMIC STRUCTURE OF NUCLEIC ACIDS AND THEIR ANALOGS IN DNA REPLICATION, EXTRA- AND INTRA-CELLULAR TRANSPORT; MOLECULAR CROWDING BY THE USE OF IONIC LIQUIDS; NEW TECHNOLOGIES ENABLING THE MODIFICATION OF GENE EXPRESSION VIA EDITING OF THERAPEUTIC GENES; THE USE OF RIBOSWITCHES; THE MODIFICATION OF MRNA CAP REGIONS; NEW APPROACHES TO DETECT APPROPRIATELY MODIFIED RNAS WITH EPR SPECTROSCOPY AND THE USE OF PARALLEL AND HIGH-THROUGHPUT TECHNIQUES FOR THE ANALYSIS OF THE STRUCTURE AND NEW FUNCTIONS OF NUCLEIC ACIDS. THIS VOLUME DISCUSSES HOW CHEMISTRY CAN ADD NEW FRONTIERS TO THE FIELD OF NUCLEIC ACIDS IN MOLECULAR MEDICINE, BIOTECHNOLOGY AND NANOTECHNOLOGY AND IS NOT ONLY AN INVALUABLE SOURCE OF INFORMATION TO CHEMISTS, BIOCHEMISTS AND LIFE SCIENTISTS BUT WILL ALSO STIMULATE FUTURE RESEARCH DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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series2	RNA Technologies
spelling	Chemical Biology of Nucleic Acids Fundamentals and Clinical Applications Volker A. Erdmann ; Wojciech T. Markiewicz ; Jan Barciszewski, ed. Berlin [u.a.] Springer 2014 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier RNA Technologies Biowissenschaften Medizin Life sciences Human genetics Medicine Nucleic acids Chemische Biologie (DE-588)7657972-4 gnd rswk-swf RNS (DE-588)4076759-0 gnd rswk-swf Molekulare Medizin (DE-588)4543844-4 gnd rswk-swf Klinische Medizin (DE-588)4134748-1 gnd rswk-swf Biochemie (DE-588)4006777-4 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Nucleinsäuren (DE-588)4172117-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Nucleinsäuren (DE-588)4172117-2 s Molekularbiologie (DE-588)4039983-7 s Molekulare Medizin (DE-588)4543844-4 s DE-604 Biochemie (DE-588)4006777-4 s Klinische Medizin (DE-588)4134748-1 s RNS (DE-588)4076759-0 s Chemische Biologie (DE-588)7657972-4 s 1\p DE-604 Erdmann, Volker A. 1941-2015 Sonstige (DE-588)130682349 oth Markiewicz, Wojciech T. Sonstige oth Barciszewski, Jan Sonstige oth Erscheint auch als Druckausgabe 978-3-642-54451-4 https://doi.org/10.1007/978-3-642-54452-1 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027358977&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027358977&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk
spellingShingle	Chemical Biology of Nucleic Acids Fundamentals and Clinical Applications Biowissenschaften Medizin Life sciences Human genetics Medicine Nucleic acids Chemische Biologie (DE-588)7657972-4 gnd RNS (DE-588)4076759-0 gnd Molekulare Medizin (DE-588)4543844-4 gnd Klinische Medizin (DE-588)4134748-1 gnd Biochemie (DE-588)4006777-4 gnd Molekularbiologie (DE-588)4039983-7 gnd Nucleinsäuren (DE-588)4172117-2 gnd
subject_GND	(DE-588)7657972-4 (DE-588)4076759-0 (DE-588)4543844-4 (DE-588)4134748-1 (DE-588)4006777-4 (DE-588)4039983-7 (DE-588)4172117-2 (DE-588)4143413-4
title	Chemical Biology of Nucleic Acids Fundamentals and Clinical Applications
title_auth	Chemical Biology of Nucleic Acids Fundamentals and Clinical Applications
title_exact_search	Chemical Biology of Nucleic Acids Fundamentals and Clinical Applications
title_full	Chemical Biology of Nucleic Acids Fundamentals and Clinical Applications Volker A. Erdmann ; Wojciech T. Markiewicz ; Jan Barciszewski, ed.
title_fullStr	Chemical Biology of Nucleic Acids Fundamentals and Clinical Applications Volker A. Erdmann ; Wojciech T. Markiewicz ; Jan Barciszewski, ed.
title_full_unstemmed	Chemical Biology of Nucleic Acids Fundamentals and Clinical Applications Volker A. Erdmann ; Wojciech T. Markiewicz ; Jan Barciszewski, ed.
title_short	Chemical Biology of Nucleic Acids
title_sort	chemical biology of nucleic acids fundamentals and clinical applications
title_sub	Fundamentals and Clinical Applications
topic	Biowissenschaften Medizin Life sciences Human genetics Medicine Nucleic acids Chemische Biologie (DE-588)7657972-4 gnd RNS (DE-588)4076759-0 gnd Molekulare Medizin (DE-588)4543844-4 gnd Klinische Medizin (DE-588)4134748-1 gnd Biochemie (DE-588)4006777-4 gnd Molekularbiologie (DE-588)4039983-7 gnd Nucleinsäuren (DE-588)4172117-2 gnd
topic_facet	Biowissenschaften Medizin Life sciences Human genetics Medicine Nucleic acids Chemische Biologie RNS Molekulare Medizin Klinische Medizin Biochemie Molekularbiologie Nucleinsäuren Aufsatzsammlung
url	https://doi.org/10.1007/978-3-642-54452-1 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027358977&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027358977&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA
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