Molecular Diagnostics for Dermatology: Practical Applications of Molecular Testing for the Diagnosis and Management of the Dermatology Patient
This textbook presents the current (and near-future) state of affairs of molecular testing as it pertains to the dermatology patient. It focuses on practical applications of molecular diagnostics over a cross-section of dermatologic disease, including melanoma, lymphoma, soft tissue tumors, genoderm...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Heidelberg [u.a.]
Springer
2014
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| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | This textbook presents the current (and near-future) state of affairs of molecular testing as it pertains to the dermatology patient. It focuses on practical applications of molecular diagnostics over a cross-section of dermatologic disease, including melanoma, lymphoma, soft tissue tumors, genodermatoses, and infectious disease. It includes practical advice to those ordering molecular tests as well as to those considering performing such tests, providing a potential template for a comprehensive dermatologic molecular diagnostics test menu. Pitfalls of interpretation and algorithmic approaches to testing are included. The textbook is directed towards all readers - clinicians, pathologists, laboratorians, and other inquisitive minds - independent of their level of molecular expertise, to provoke thought or perhaps even change practice. The context for the book is the rapid evolution of the field of molecular diagnostics, which is becoming more pervasive in all disciplines of medicine, including dermatology. This is indeed an exciting time in dermatology. Molecular testing is now incorporated into all aspects of patient management, including diagnostics (identifying and classifying disease), prognostics (predicting disease course), and theranostics (predicting response to therapy). For example, molecular tests are now used to detect germline mutations that result in genodermatoses, somatic genetic events that characterize tumors such as melanoma and sarcomas, and genetic material of otherwise undetectable infectious organisms. For melanoma and lymphoma, testing can potentially predict tumor behavior and modify patient staging. Regarding theranostics, molecular tests that identify specific mutations in proto-oncogenes, such as BRAF and others, are now used to predict which patients will respond to designer targeted therapies. |
| Beschreibung: | online resource |
| ISBN: | 9783642540653 9783642540660 |
| DOI: | 10.1007/978-3-642-54066-0 |
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| 520 | 1 | |a This textbook presents the current (and near-future) state of affairs of molecular testing as it pertains to the dermatology patient. It focuses on practical applications of molecular diagnostics over a cross-section of dermatologic disease, including melanoma, lymphoma, soft tissue tumors, genodermatoses, and infectious disease. It includes practical advice to those ordering molecular tests as well as to those considering performing such tests, providing a potential template for a comprehensive dermatologic molecular diagnostics test menu. Pitfalls of interpretation and algorithmic approaches to testing are included. The textbook is directed towards all readers - clinicians, pathologists, laboratorians, and other inquisitive minds - independent of their level of molecular expertise, to provoke thought or perhaps even change practice. The context for the book is the rapid evolution of the field of molecular diagnostics, which is becoming more pervasive in all disciplines of medicine, including dermatology. This is indeed an exciting time in dermatology. Molecular testing is now incorporated into all aspects of patient management, including diagnostics (identifying and classifying disease), prognostics (predicting disease course), and theranostics (predicting response to therapy). For example, molecular tests are now used to detect germline mutations that result in genodermatoses, somatic genetic events that characterize tumors such as melanoma and sarcomas, and genetic material of otherwise undetectable infectious organisms. For melanoma and lymphoma, testing can potentially predict tumor behavior and modify patient staging. Regarding theranostics, molecular tests that identify specific mutations in proto-oncogenes, such as BRAF and others, are now used to predict which patients will respond to designer targeted therapies. | |
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| doi_str_mv | 10.1007/978-3-642-54066-0 |
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| id | DE-604.BV041851500 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:06:54Z |
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| isbn | 9783642540653 9783642540660 |
| language | English |
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| spelling | Hosler, Gregory A. Verfasser aut Molecular Diagnostics for Dermatology Practical Applications of Molecular Testing for the Diagnosis and Management of the Dermatology Patient Gregory A. Hosler ; Kathleen M. Murphy Heidelberg [u.a.] Springer 2014 online resource txt rdacontent c rdamedia cr rdacarrier This textbook presents the current (and near-future) state of affairs of molecular testing as it pertains to the dermatology patient. It focuses on practical applications of molecular diagnostics over a cross-section of dermatologic disease, including melanoma, lymphoma, soft tissue tumors, genodermatoses, and infectious disease. It includes practical advice to those ordering molecular tests as well as to those considering performing such tests, providing a potential template for a comprehensive dermatologic molecular diagnostics test menu. Pitfalls of interpretation and algorithmic approaches to testing are included. The textbook is directed towards all readers - clinicians, pathologists, laboratorians, and other inquisitive minds - independent of their level of molecular expertise, to provoke thought or perhaps even change practice. The context for the book is the rapid evolution of the field of molecular diagnostics, which is becoming more pervasive in all disciplines of medicine, including dermatology. This is indeed an exciting time in dermatology. Molecular testing is now incorporated into all aspects of patient management, including diagnostics (identifying and classifying disease), prognostics (predicting disease course), and theranostics (predicting response to therapy). For example, molecular tests are now used to detect germline mutations that result in genodermatoses, somatic genetic events that characterize tumors such as melanoma and sarcomas, and genetic material of otherwise undetectable infectious organisms. For melanoma and lymphoma, testing can potentially predict tumor behavior and modify patient staging. Regarding theranostics, molecular tests that identify specific mutations in proto-oncogenes, such as BRAF and others, are now used to predict which patients will respond to designer targeted therapies. Online-Ausgabe Online-Ressource (XVIII, 356 p. 83 illus., 79 illus. in color) Springer eBook Collection / Medicine aMedicine aMedical laboratories aDermatology aPathology Murphy, Kathleen M. Verfasser aut Reproduktion von Hosler, Gregory A. Molecular Diagnostics for Dermatology 2014 https://doi.org/10.1007/978-3-642-54066-0 Verlag Volltext |
| spellingShingle | Hosler, Gregory A. Murphy, Kathleen M. Molecular Diagnostics for Dermatology Practical Applications of Molecular Testing for the Diagnosis and Management of the Dermatology Patient aMedicine aMedical laboratories aDermatology aPathology |
| title | Molecular Diagnostics for Dermatology Practical Applications of Molecular Testing for the Diagnosis and Management of the Dermatology Patient |
| title_auth | Molecular Diagnostics for Dermatology Practical Applications of Molecular Testing for the Diagnosis and Management of the Dermatology Patient |
| title_exact_search | Molecular Diagnostics for Dermatology Practical Applications of Molecular Testing for the Diagnosis and Management of the Dermatology Patient |
| title_full | Molecular Diagnostics for Dermatology Practical Applications of Molecular Testing for the Diagnosis and Management of the Dermatology Patient Gregory A. Hosler ; Kathleen M. Murphy |
| title_fullStr | Molecular Diagnostics for Dermatology Practical Applications of Molecular Testing for the Diagnosis and Management of the Dermatology Patient Gregory A. Hosler ; Kathleen M. Murphy |
| title_full_unstemmed | Molecular Diagnostics for Dermatology Practical Applications of Molecular Testing for the Diagnosis and Management of the Dermatology Patient Gregory A. Hosler ; Kathleen M. Murphy |
| title_short | Molecular Diagnostics for Dermatology |
| title_sort | molecular diagnostics for dermatology practical applications of molecular testing for the diagnosis and management of the dermatology patient |
| title_sub | Practical Applications of Molecular Testing for the Diagnosis and Management of the Dermatology Patient |
| topic | aMedicine aMedical laboratories aDermatology aPathology |
| topic_facet | aMedicine aMedical laboratories aDermatology aPathology |
| url | https://doi.org/10.1007/978-3-642-54066-0 |
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