Telomerases: chemistry, biology and clinical applications
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hoboken, NJ
Wiley
2012
|
| Schlagworte: | |
| Online-Zugang: | Volltext Buchcover |
| Beschreibung: | "This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed"--Provided by publisher |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9781118268667 9781118268506 9781118267516 9780470592045 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV041828933 | ||
| 003 | DE-604 | ||
| 005 | 20140627 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 140506s2012 |||| o||u| ||||||eng d | ||
| 020 | |a 9781118268667 |c Online |9 978-1-118-26866-7 | ||
| 020 | |a 9781118268506 |c ePDF |9 978-1-118-26850-6 | ||
| 020 | |a 9781118267516 |c ePub |9 978-1-118-26751-6 | ||
| 020 | |a 9780470592045 |c Print |9 978-0-470-59204-5 | ||
| 024 | 7 | |a 10.1002/9781118268667 |2 doi | |
| 035 | |a (OCoLC)793995927 | ||
| 035 | |a (DE-599)BVBBV041828933 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-703 |a DE-861 | ||
| 082 | 0 | |a 572.7 | |
| 084 | |a WD 5060 |0 (DE-625)148187: |2 rvk | ||
| 245 | 1 | 0 | |a Telomerases |b chemistry, biology and clinical applications |c edited by Neal F. Lue and Chantal Autexier |
| 264 | 1 | |a Hoboken, NJ |b Wiley |c 2012 | |
| 300 | |a 1 Online-Ressource | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 500 | |a "This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed"--Provided by publisher | ||
| 505 | 0 | |a The telomerase complex : an overview / Johanna Mancini and Chantal Autexier -- Telomerase RNA : structure, function, and molecular mechanisms / Yehudi Tzfati and Julian J.-L. Chen -- TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes and Neal F. Lue -- Telomerase biogenesis : RNA Processing, trafficking and protein Interactions / Tara Beattie and Pascal Chartrand -- Transcriptional regulation of human telomerase / Antonella Farsetti and Yu-Sheng Cong -- Telomerase regulation and telomere length homeostasis / Joachim Lingner and David Shore -- Telomere structure in telomerase regulation / Momchil D. Vodenicharov and Raymund J. Wellinger -- Off-telomere functions of telomerase / Kenkichi Masutomi and William C. Hahn -- Murine Models of Dysfunctional Telomeres and Telomerase / Yie Liu and Lea Harrington -- Cellular senescence, telomerase, and cancer in human cells / Phillip G. Smiraldo ... [et al.] -- Telomerase, retrotransposons, and evolution / Irina R. Arkhipova | |
| 650 | 4 | |a Natural history | |
| 650 | 4 | |a Science | |
| 650 | 7 | |a SCIENCE / Life Sciences / Molecular Biology |2 bisacsh | |
| 650 | 7 | |a SCIENCE / Life Sciences / Genetics & Genomics |2 bisacsh | |
| 650 | 4 | |a Telomerase | |
| 650 | 4 | |a Naturwissenschaft | |
| 650 | 4 | |a Telomerase / Physiology | |
| 650 | 4 | |a Telomerase / Metabolism | |
| 650 | 4 | |a Telomerase / Genetics | |
| 650 | 4 | |a Geriatrics | |
| 650 | 0 | 7 | |a Telomerase |0 (DE-588)4513124-7 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Telomerase |0 (DE-588)4513124-7 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Lue, Neal F. |d 1962- |e Sonstige |0 (DE-588)1027360858 |4 oth | |
| 700 | 1 | |a Autexier, Chantal |d 1963- |e Sonstige |0 (DE-588)1027360920 |4 oth | |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/book/10.1002/9781118268667 |x Verlag |3 Volltext |
| 856 | 4 | 2 | |m SWB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027273852&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Buchcover |
| 912 | |a ZDB-35-WCB |a ZDB-35-WIC | ||
| 940 | 1 | |q UBT_ZDB-35-WCB_2012 | |
| 940 | 1 | |q FRO_PDA_WIC | |
| 940 | 1 | |q UBG_PDA_WIC | |
| 940 | 1 | |q FHR_PDA_WIC | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-027273852 | ||
Datensatz im Suchindex
| _version_ | 1804152163804381184 |
|---|---|
| any_adam_object | 1 |
| author_GND | (DE-588)1027360858 (DE-588)1027360920 |
| building | Verbundindex |
| bvnumber | BV041828933 |
| classification_rvk | WD 5060 |
| collection | ZDB-35-WCB ZDB-35-WIC |
| contents | The telomerase complex : an overview / Johanna Mancini and Chantal Autexier -- Telomerase RNA : structure, function, and molecular mechanisms / Yehudi Tzfati and Julian J.-L. Chen -- TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes and Neal F. Lue -- Telomerase biogenesis : RNA Processing, trafficking and protein Interactions / Tara Beattie and Pascal Chartrand -- Transcriptional regulation of human telomerase / Antonella Farsetti and Yu-Sheng Cong -- Telomerase regulation and telomere length homeostasis / Joachim Lingner and David Shore -- Telomere structure in telomerase regulation / Momchil D. Vodenicharov and Raymund J. Wellinger -- Off-telomere functions of telomerase / Kenkichi Masutomi and William C. Hahn -- Murine Models of Dysfunctional Telomeres and Telomerase / Yie Liu and Lea Harrington -- Cellular senescence, telomerase, and cancer in human cells / Phillip G. Smiraldo ... [et al.] -- Telomerase, retrotransposons, and evolution / Irina R. Arkhipova |
| ctrlnum | (OCoLC)793995927 (DE-599)BVBBV041828933 |
| dewey-full | 572.7 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.7 |
| dewey-search | 572.7 |
| dewey-sort | 3572.7 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03868nmm a2200601zc 4500</leader><controlfield tag="001">BV041828933</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20140627 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">140506s2012 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781118268667</subfield><subfield code="c">Online</subfield><subfield code="9">978-1-118-26866-7</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781118268506</subfield><subfield code="c">ePDF</subfield><subfield code="9">978-1-118-26850-6</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781118267516</subfield><subfield code="c">ePub</subfield><subfield code="9">978-1-118-26751-6</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780470592045</subfield><subfield code="c">Print</subfield><subfield code="9">978-0-470-59204-5</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1002/9781118268667</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)793995927</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV041828933</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-703</subfield><subfield code="a">DE-861</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">572.7</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WD 5060</subfield><subfield code="0">(DE-625)148187:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Telomerases</subfield><subfield code="b">chemistry, biology and clinical applications</subfield><subfield code="c">edited by Neal F. Lue and Chantal Autexier</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Hoboken, NJ</subfield><subfield code="b">Wiley</subfield><subfield code="c">2012</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">"This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed"--Provided by publisher</subfield></datafield><datafield tag="505" ind1="0" ind2=" "><subfield code="a">The telomerase complex : an overview / Johanna Mancini and Chantal Autexier -- Telomerase RNA : structure, function, and molecular mechanisms / Yehudi Tzfati and Julian J.-L. Chen -- TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes and Neal F. Lue -- Telomerase biogenesis : RNA Processing, trafficking and protein Interactions / Tara Beattie and Pascal Chartrand -- Transcriptional regulation of human telomerase / Antonella Farsetti and Yu-Sheng Cong -- Telomerase regulation and telomere length homeostasis / Joachim Lingner and David Shore -- Telomere structure in telomerase regulation / Momchil D. Vodenicharov and Raymund J. Wellinger -- Off-telomere functions of telomerase / Kenkichi Masutomi and William C. Hahn -- Murine Models of Dysfunctional Telomeres and Telomerase / Yie Liu and Lea Harrington -- Cellular senescence, telomerase, and cancer in human cells / Phillip G. Smiraldo ... [et al.] -- Telomerase, retrotransposons, and evolution / Irina R. Arkhipova</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Natural history</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Science</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">SCIENCE / Life Sciences / Molecular Biology</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">SCIENCE / Life Sciences / Genetics & Genomics</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Telomerase</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Naturwissenschaft</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Telomerase / Physiology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Telomerase / Metabolism</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Telomerase / Genetics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Geriatrics</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Telomerase</subfield><subfield code="0">(DE-588)4513124-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Telomerase</subfield><subfield code="0">(DE-588)4513124-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lue, Neal F.</subfield><subfield code="d">1962-</subfield><subfield code="e">Sonstige</subfield><subfield code="0">(DE-588)1027360858</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Autexier, Chantal</subfield><subfield code="d">1963-</subfield><subfield code="e">Sonstige</subfield><subfield code="0">(DE-588)1027360920</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://onlinelibrary.wiley.com/doi/book/10.1002/9781118268667</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">SWB Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027273852&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Buchcover</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-35-WCB</subfield><subfield code="a">ZDB-35-WIC</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">UBT_ZDB-35-WCB_2012</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">FRO_PDA_WIC</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">UBG_PDA_WIC</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">FHR_PDA_WIC</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-027273852</subfield></datafield></record></collection> |
| id | DE-604.BV041828933 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T01:06:21Z |
| institution | BVB |
| isbn | 9781118268667 9781118268506 9781118267516 9780470592045 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-027273852 |
| oclc_num | 793995927 |
| open_access_boolean | |
| owner | DE-703 DE-861 |
| owner_facet | DE-703 DE-861 |
| physical | 1 Online-Ressource |
| psigel | ZDB-35-WCB ZDB-35-WIC UBT_ZDB-35-WCB_2012 FRO_PDA_WIC UBG_PDA_WIC FHR_PDA_WIC |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | Wiley |
| record_format | marc |
| spelling | Telomerases chemistry, biology and clinical applications edited by Neal F. Lue and Chantal Autexier Hoboken, NJ Wiley 2012 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier "This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed"--Provided by publisher The telomerase complex : an overview / Johanna Mancini and Chantal Autexier -- Telomerase RNA : structure, function, and molecular mechanisms / Yehudi Tzfati and Julian J.-L. Chen -- TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes and Neal F. Lue -- Telomerase biogenesis : RNA Processing, trafficking and protein Interactions / Tara Beattie and Pascal Chartrand -- Transcriptional regulation of human telomerase / Antonella Farsetti and Yu-Sheng Cong -- Telomerase regulation and telomere length homeostasis / Joachim Lingner and David Shore -- Telomere structure in telomerase regulation / Momchil D. Vodenicharov and Raymund J. Wellinger -- Off-telomere functions of telomerase / Kenkichi Masutomi and William C. Hahn -- Murine Models of Dysfunctional Telomeres and Telomerase / Yie Liu and Lea Harrington -- Cellular senescence, telomerase, and cancer in human cells / Phillip G. Smiraldo ... [et al.] -- Telomerase, retrotransposons, and evolution / Irina R. Arkhipova Natural history Science SCIENCE / Life Sciences / Molecular Biology bisacsh SCIENCE / Life Sciences / Genetics & Genomics bisacsh Telomerase Naturwissenschaft Telomerase / Physiology Telomerase / Metabolism Telomerase / Genetics Geriatrics Telomerase (DE-588)4513124-7 gnd rswk-swf Telomerase (DE-588)4513124-7 s DE-604 Lue, Neal F. 1962- Sonstige (DE-588)1027360858 oth Autexier, Chantal 1963- Sonstige (DE-588)1027360920 oth https://onlinelibrary.wiley.com/doi/book/10.1002/9781118268667 Verlag Volltext SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027273852&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Buchcover |
| spellingShingle | Telomerases chemistry, biology and clinical applications The telomerase complex : an overview / Johanna Mancini and Chantal Autexier -- Telomerase RNA : structure, function, and molecular mechanisms / Yehudi Tzfati and Julian J.-L. Chen -- TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes and Neal F. Lue -- Telomerase biogenesis : RNA Processing, trafficking and protein Interactions / Tara Beattie and Pascal Chartrand -- Transcriptional regulation of human telomerase / Antonella Farsetti and Yu-Sheng Cong -- Telomerase regulation and telomere length homeostasis / Joachim Lingner and David Shore -- Telomere structure in telomerase regulation / Momchil D. Vodenicharov and Raymund J. Wellinger -- Off-telomere functions of telomerase / Kenkichi Masutomi and William C. Hahn -- Murine Models of Dysfunctional Telomeres and Telomerase / Yie Liu and Lea Harrington -- Cellular senescence, telomerase, and cancer in human cells / Phillip G. Smiraldo ... [et al.] -- Telomerase, retrotransposons, and evolution / Irina R. Arkhipova Natural history Science SCIENCE / Life Sciences / Molecular Biology bisacsh SCIENCE / Life Sciences / Genetics & Genomics bisacsh Telomerase Naturwissenschaft Telomerase / Physiology Telomerase / Metabolism Telomerase / Genetics Geriatrics Telomerase (DE-588)4513124-7 gnd |
| subject_GND | (DE-588)4513124-7 |
| title | Telomerases chemistry, biology and clinical applications |
| title_auth | Telomerases chemistry, biology and clinical applications |
| title_exact_search | Telomerases chemistry, biology and clinical applications |
| title_full | Telomerases chemistry, biology and clinical applications edited by Neal F. Lue and Chantal Autexier |
| title_fullStr | Telomerases chemistry, biology and clinical applications edited by Neal F. Lue and Chantal Autexier |
| title_full_unstemmed | Telomerases chemistry, biology and clinical applications edited by Neal F. Lue and Chantal Autexier |
| title_short | Telomerases |
| title_sort | telomerases chemistry biology and clinical applications |
| title_sub | chemistry, biology and clinical applications |
| topic | Natural history Science SCIENCE / Life Sciences / Molecular Biology bisacsh SCIENCE / Life Sciences / Genetics & Genomics bisacsh Telomerase Naturwissenschaft Telomerase / Physiology Telomerase / Metabolism Telomerase / Genetics Geriatrics Telomerase (DE-588)4513124-7 gnd |
| topic_facet | Natural history Science SCIENCE / Life Sciences / Molecular Biology SCIENCE / Life Sciences / Genetics & Genomics Telomerase Naturwissenschaft Telomerase / Physiology Telomerase / Metabolism Telomerase / Genetics Geriatrics |
| url | https://onlinelibrary.wiley.com/doi/book/10.1002/9781118268667 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027273852&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT luenealf telomeraseschemistrybiologyandclinicalapplications AT autexierchantal telomeraseschemistrybiologyandclinicalapplications |