Bioinorganic chemistry:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Oxford
Oxford Univ. Press
2014
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | X, 230 S., [2] Bl. Ill., graph. Darst. |
| ISBN: | 9780199655199 |
Internformat
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Datensatz im Suchindex
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|---|---|
| adam_text | Contents Introduction ix 1 Bio-elements in the periodic table 1 2 Pre-life and early life forms; extremophiles 7 3 4 5 6 7 2.1 What is Life, and how did Life evolve? 2.2 Extremophiles The alkaline and alkaline earth metals 16 3.1 Overview 16 3.2 Ion channels 20 3.3 Sodium and potassium 23 3.4 Magnesium 25 3.5 Calcium 27 Iron: general features of its inorganic chemistry and biochemistry 34 4.1 General and aqueous chemistry 34 4.2 Mobilization, transport, delivery, and mineralizationof iron 39 Oxygen transport and the respiratory chain 52 5.1 Oxygen and oxygen transport by haemoglobin andmyoglobin 53 5.2 Oxygen transport by haemerythrin and haemocyanin 57 5.3 The respiratory chain 59 Oxidoreductases based on iron, manganese, and copper 65 6.1 Ribonucleotide reductases 66 6.2 Superoxide dlsmutases, superoxide reductases, andperoxidases 68 6.3 Oxygenases and oxidases 71 Охо-transfer proteins based on molybdenum, tungsten, and vanadium 7.1 8 7 13 81 Molybdo- and tungsto-pyranopterins 82 7.1.1 The xanthine oxidase family 82 7.1.2 The sulfite oxidase family 85 7.1.3 The dimethyl sulfoxide (DMSO) reductase family 86 7.1.4 The aldehyde:ferredoxin oxidoreductase family 87 7.2 Vanadate-dependent haloperoxldases 88 7.3 Model chemistry 90 The sulfur cycle 94 8.1 Environmental sulfur cycling 95 8.2 Biogenic metabolism of sulfur 97
vi CONTENTS 9 10 11 12 13 14 Nitrogenase and nitrogen cycle enzymes 102 9.1 Overview and native nitrogenase 102 9.2 Nitrogenase models and model reactions 108 9.3 Denitrification 111 9.4 Nitric oxide 115 The methane cycle and nickel enzymes 121 10.1 122 Introduction 10.2 Methanogenesis 122 10.3 Biogenic oxidation of methane 126 10.4 Nickel enzymes not involved in methane metabolism 127 Photosynthesis 136 11.1 Overview 11.2 The reaction pathway _ 136 138 11.3 Modelling photosynthesis 145 The biochemistry of zinc 151 12.1 An overview of zinc 151 12.2 Zinc enzymes 156 12.2.1 Carboanhydrase 156 12.2.2 Hydrolases 157 12.2.3 Alcohol dehydrogenase 162 12.3 The. role of zinc in the transcription of genes 164 12.4 Thioneins 165 Metal-and metalloid-carbon bonds 169 13.1 Organometallic compounds of transition metals 169 13.2 Carbon bonds to main group metalsand metalloids 177 13.2.1 Mercury 177 13.2.2 Lead 180 13.2.3 Selenium 180 13.2.4 Arsenic 182 Inorganics in medicine 187 14.1 Metals and metalloids: an introduction 188 14.2 Dysfunction of iron and copper homeostasis 190 14.2.1 Iron 191 14.2.2 Copper 192 14.3 Metals and metalloids in therapy 14.3.1 Historical and general notes 196 196 14.3.2 Treatment of arthritis with gold compounds 198 14.3.3 Cancer treatment 200
CONTENTS Index 14.3.4 Further metal-based medications 206 14.3.5 Radiopharmaceuticals 210 14.4 Metals and metalloids in diagnostic imaging 213 14.5 The toxic and therapeutic potential of CO,NO, and H2S 217 226 vii
Bioinorganic chemistry Nes at the interface of inorganic chemistry and biochemistry, and explores the function of inorganic species in living systems-from the iron that helps our red blood cells transport oxygen to our tissues, to the calcium that forms an integral part of our bones. In his book, Dieter Rehder provides a succinct overview of this dynamic field, reviewing the key chemical elements that have important biological function, and exploring how the chemistry of these elements is central to the mode of operation of biological systems. A truly student-friendly account of this buoyant area of chemistry Broad, balanced coverage makes it the perfect resource both for those encountering the field for the first time, and those wishing to refresh and broaden their understanding of essential blolnorganic concepts Places particular emphasis on biological functions as related to specific chemical elements, unifying the fields of chemistry and biology in a coherent way Provides insights into the role of inorganic compounds in medicinal contexts, including diagnosis and therapy Sidebars review underlying principles of importance to the subject-including the concepts of magnetism and chirality—and discuss the analytical approaches adopted to study bioinorganic systems, helping readers to appreciate the experimental basis of the subject
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| dewey-tens | 570 - Biology |
| discipline | Chemie / Pharmazie Biologie Chemie |
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| indexdate | 2024-07-10T01:06:14Z |
| institution | BVB |
| isbn | 9780199655199 |
| language | English |
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| publishDate | 2014 |
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| spelling | Rehder, Dieter 1941- Verfasser (DE-588)106815539 aut Bioinorganic chemistry Dieter Rehder Oxford Oxford Univ. Press 2014 X, 230 S., [2] Bl. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Bioanorganische Chemie (DE-588)4126727-8 gnd rswk-swf Bioanorganische Chemie (DE-588)4126727-8 s DE-604 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027269193&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027269193&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Rehder, Dieter 1941- Bioinorganic chemistry Bioanorganische Chemie (DE-588)4126727-8 gnd |
| subject_GND | (DE-588)4126727-8 |
| title | Bioinorganic chemistry |
| title_auth | Bioinorganic chemistry |
| title_exact_search | Bioinorganic chemistry |
| title_full | Bioinorganic chemistry Dieter Rehder |
| title_fullStr | Bioinorganic chemistry Dieter Rehder |
| title_full_unstemmed | Bioinorganic chemistry Dieter Rehder |
| title_short | Bioinorganic chemistry |
| title_sort | bioinorganic chemistry |
| topic | Bioanorganische Chemie (DE-588)4126727-8 gnd |
| topic_facet | Bioanorganische Chemie |
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