The role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in atherosclerosis:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 112 S. Ill., graph. Darst. |
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Datensatz im Suchindex
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| adam_text | TABLE OF CONTENTS:
TABLE OF CONTENTS 3
ABBREVIATION 6
I INTRODUCTION 8
1.1 ATHEROSCLEROSIS 8
1.2 CYTOKINES 11
1.3 CHEMOKINES 12
1.4 VASCULAR REMODELING 12
1.5 INFLAMMATORY CELL INVOLVEMENT IN ATHEROSCLEROSIS 13
1.6 MONOCYTES 14
1.7 MACROPHAGES 17
1.8 DENDRITIC CELLS 18
1.9 T-CELLS 20
1.10 NATURAL KILLER CELLS 24
1.11 MAST-CELLS 26
1.12 B-CELLS 27
1.13 NEUTROPHILS 29
1.14 PLATELETS 31
1.15 CO-STIMULATORY MOLECULES 32
1.16 MAJOR FAMILIES OF CO-STIMULATORY MOLECULES 33
1.17 CTLA-4 40
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HTTP://D-NB.INFO/1048341100
1.18 ABATACEPT 48
1.19 GITR 51
11. MATERIAL AND METHODS 55
11.1 GENERAL EQUIPMENT 55
11.2 ANTIBODIES 57
11.2.1 PRIMARY ANTIBODIES 57
11.2.2 DIRECTLY CONJUGATED ANTIBODIES 58
11.2.3 SECONDARY ANTIBODIES 59
11.2.4 BLOCKING ANTIBODIES 59
11.3 BUFFERS 60
11.4 ANIMAL EXPERIMENTS 61
11.4.1 MICE 61
11.4.2 MOUSE MODEL OF ATHEROSCLEROSIS 61
11.4.3 TISSUE HANDLING 62
11.4.4 BLOOD PREPARATION 63
11.4.5 AORTIC ROOT PREPARATION 63
11.4.6 AORTIC ARCH PROCESSING 63
11.4.7 CUTTING PARAFFIN-EMBEDDED AORTIC ARCHES 64
11.4.8 BONE MARROW TRANSPLANTATION 65
11.5 CELL CHARACTERIZATION AND PROTEIN ASSAYS 65
11.5.1 FLOW CYTOMETRY 65
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II.5.2 HISTOCHEMISTRY 67
II.6 DATA ILLUSTRATION AND STATISTICAL ANALYSIS 69
III. RESULTS 70
IV. DISCUSSION 86
V. REFERENCES 94
VI. ACKNOWLEDGEMENT 108
VII. CURRICULUM VITAE 110
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| any_adam_object | 1 |
| author | Sanati, Maryam |
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| dewey-ones | 610 - Medicine and health |
| dewey-raw | 610 |
| dewey-search | 610 |
| dewey-sort | 3610 |
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| discipline | Medizin |
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| spelling | Sanati, Maryam Verfasser (DE-588)1045998834 aut The role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in atherosclerosis vorgelegt von Maryam Sanati 2013 112 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Aachen, Techn. Hochsch., Diss., 2013 (DE-588)4113937-9 Hochschulschrift gnd-content DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027257296&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Sanati, Maryam The role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in atherosclerosis |
| subject_GND | (DE-588)4113937-9 |
| title | The role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in atherosclerosis |
| title_auth | The role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in atherosclerosis |
| title_exact_search | The role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in atherosclerosis |
| title_full | The role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in atherosclerosis vorgelegt von Maryam Sanati |
| title_fullStr | The role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in atherosclerosis vorgelegt von Maryam Sanati |
| title_full_unstemmed | The role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in atherosclerosis vorgelegt von Maryam Sanati |
| title_short | The role of cytotoxic T lymphocyte antigen 4 (CTLA-4) in atherosclerosis |
| title_sort | the role of cytotoxic t lymphocyte antigen 4 ctla 4 in atherosclerosis |
| topic_facet | Hochschulschrift |
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