Tissue regeneration: where nano-structure meets biology
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New Jersey [u.a.]
World Scientific
2014
|
| Schriftenreihe: | Frontiers in nanobiomedical research
2 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XXIII, 521 S. |
| ISBN: | 9789814494830 |
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| 245 | 1 | 0 | |a Tissue regeneration |b where nano-structure meets biology |c ed. Qing Liu & Hongjun Wang |
| 264 | 1 | |a New Jersey [u.a.] |b World Scientific |c 2014 | |
| 300 | |a XXIII, 521 S. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Frontiers in nanobiomedical research |v 2 | |
| 500 | |a Includes bibliographical references and index | ||
| 650 | 2 | |a Tissue Engineering | |
| 650 | 2 | |a Regeneration | |
| 650 | 2 | |a Nanostructures | |
| 700 | 1 | |a Liu, Qing |e Sonstige |4 oth | |
| 830 | 0 | |a Frontiers in nanobiomedical research |v 2 |w (DE-604)BV040947210 |9 2 | |
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Datensatz im Suchindex
| _version_ | 1804152044306563072 |
|---|---|
| adam_text | Titel: Tissue regeneration
Autor: Liu, Qing
Jahr: 2014
Contents
Preface............................................................................................v
List of Contributors......................................................................xix
Chapter 1 Adult Stem Cells: From Bench-Top to Bedside......1
Henry E. Young, Lee Hyer, Asa C. Black Jr
and Joe Sam Robinson Jr
1. Introduction..............................................................................2
2. Classification of Stem Cells........................................................6
3. Stem Cell Isolation and Cultivation.........................................19
3.1. Isolation...........................................................................19
3.2. Cultivation.......................................................................19
3.3. Replating.........................................................................20
3.4. Cryopreservation.............................................................21
3.5. Assaying for cell type........................................................22
4. Parkinson Disease and Potential of Stem Cell...........................26
4.1. Bench-top animal model for Parkinson disease.................35
4.2. Bedside phase-0 efficacy trial for Parkinson disease...........38
5. Future Perspective...................................................................50
6. Concluding Remarks................................................................54
Acknowledgments.........................................................................55
References....................................................................................56
Chapter 2 Preparation of Tissue Development — Mimicking
Matrices and Their Applications............................61
Guoping Chen, Takashi Hoshiba
and Naoki Kawazoe
ix
x Contents
1. Introduction............................................................................62
2. Cell-Derived Matrices..............................................................62
3. Stepwise Osteogenesis-Mimicking Matrices..............................65
4. Stepwise Adipogenesis-Mimicking Matrices..............................68
5. Comparison of Stepwise Osteogenesis-Mimicking and
Stepwise Adipogenesis-Mimicking Matrices on Stem Cell
Differentiation.........................................................................71
6. Conclusions.............................................................................73
References....................................................................................73
Chapter 3 Decellularized Scaffolds: Concepts,
Methodologies, and Applications in
Cardiac Tissue Engineering and
Whole-Organ Regeneration ..................................77
Sourav S. Patnaik, Bo Wang, Benjamin Weed,
Jason A. Wertheim and Jun Liao
1. Introduction............................................................................78
2. History and Current State of Decellularized Approach............81
3. Methodologies in Decellularization Approaches.......................83
3.1. The balance between cell removal and ECM
preservation.....................................................................83
3.2. Current state of decellularization methodologies .............84
3.2.1. Chemicals methods...............................................84
3.2.2. Enzymatic methods...............................................86
3.2.3. Physical methods and preservation methods..........87
3.2.4. Combinations of various decellularization
methods................................................................87
3.2.5. Scaffold treatment — Sterilization, stabilization,
coating, and storage/handling...............................88
4. Application of Decellularized Scaffolds in Cardiac Tissue
Engineering.............................................................................89
4.1. Cardiac tissue engineering................................................89
4.2. Acellular myocardial scaffolds and applications.................92
4.3. Biomechanics of acellular myocardial scaffold
and its implications..........................................................93
Contents xi
5. Application of Decellularized Scaffolds
in Whole-Organ Tissue Engineering........................................97
5.1. Demands for whole-organ tissue engineering...................97
5.2. Whole-organ decellularization and its applications............98
5.2.1. Heart....................................................................99
5.2.2. Lung.....................................................................99
5.2.3. Liver...................................................................100
5.2.4. Kidney ...............................................................101
6. Discussions............................................................................102
6.1. 3D structural integrity....................................................102
6.2. Recellularization and provision of oxygen
and nutrients..................................................................103
6.3. Concluding remarks.......................................................107
Acknowledgments.......................................................................108
References..................................................................................108
Chapter 4 Recent Advances on Three-Dimensional
Electrospun Nanofiber Scaffolds for Tissue
Regeneration and Repair......................................125
Bing Ma, Matthew R. MacEwan,
Franklin D. Shuler, Matthew K. Wingate
and Jingwei Xie
1. Introduction .........................................................................126
2. fabrication of 3D Electrospun Nanofiber Scaffolds................128
2.1. Nanofiber bundles and yarns..........................................128
2.2 Tubular nanofiber structures...........................................131
2.3. Microspherical nanofiber structures................................134
2.4. Heterogeneous structures .............................................135
2.5. Regular structures formed by layer-by-layer stacking .....138
2.6. Regular structures formed by direct fiber writing ..........139
2.7. Regular structures with dimpled feature.........................140
2.8. Regular structures with patterned hexagonal features.....141
2.9. Regular structures formed by noobing and weaving.......142
3. Utilization of 3D Nanofiber Scaffolds for Tissue
Regeneration and Repair........................................................144
xii Contents
3.1. Putting tubular nanofiber scaffolds to work
for artificial blood vessels ..............................................144
3.2. Putting tubular nanofiber scaffolds to work
for nerve regeneration...................................................146
3.3. Putting layer-by-layer stacked nanofiber scaffolds
to work for annulus fibrosus regeneration .....................149
3.4. Putting 3D nanofiber scaffolds to work
for bone regeneration....................................................151
4. Conclusion and Remarks........................................................153
Acknowledgments.......................................................................155
References..................................................................................155
Chapter 5 Nanofibrous Scaffolds for Tissue Engineering
Applications: State-of-the-Art and Future
Trends...................................................................163
Masoud Mozafari, Vahid Shabafrooz,
Mostafa Yazdimamajyhani, Daryoosh Vashaee
and Lobat Tayebi
1. Nanotechnology....................................................................164
2. Electrospinning......................................................................166
2.1. Processing parameters....................................................166
2.1.1. Applied voltage...................................................167
2.1.2. Flow rate.............................................................167
2.1.3. Collector distance................................................167
2.1.4. Types of collectors..............................................168
2.2. Solution parameters.......................................................169
2.2.1. Polymer concentration........................................169
2.2.2. Solution conductivity..........................................170
2.3. Polymeric blends............................................................170
2.3.1. Blends of natural polymers..................................170
2.3.2. Blends of natural and synthetic polymers.............172
2.4. State-of-the-art and new trends......................................175
2.4.1. Need of electrospinning for tissue engineering ....175
2.4.2. Novel approaches in electrospinning....................177
2.4.3. Combined therapy with drug loaded scaffolds.....196
3. Conclusion............................................................................199
Contents xiii
Acknowledgments.......................................................................199
References..................................................................................199
Chapter 6 Extra Cellular Matrix and Its Application as
Coating on Synthetic 3D Scaffolds for
Guided Tissue Regeneration................................205
Qing Liu and Marika K. Bergenstock
1. Introduction..........................................................................206
2. Scaffold-Guided Tissue Regeneration.....................................206
3. ECM as Naturally Derived Scaffolds......................................208
4. Synthetic 3D Scaffolds Coated with Cell Culture
Derived ECM for Bone Regeneration....................................209
5. Conclusion Remarks..............................................................213
References..................................................................................214
Chapter 7 Nanodimensional and Nanocrystalline
Calcium Orthophosphates....................................219
Sergey V Dorozhkin
1. Introduction..........................................................................220
2. General Information on Nano ............................................223
3. Micron- and Submicron-Sized Calcium Orthophosphates
vs. the Nanodimensional Ones...............................................227
4. Nanodimensional and Nanocrystalline Calcium
Orthophosphates in Calcified Tissues of Mammals.................230
4.1. Bones.............................................................................230
4.2. Teeth.............................................................................232
5. The Structure of the Nanodimensional and
Nanocrystalline Apatites.........................................................233
6. Synthesis of Nanodimensional and Nanocrystalline
Calcium Orthophosphates......................................................239
6.1. General nanotechnological approaches...........................239
6.2. Nanodimensional and nanocrystalline apatites................240
6.3. Nanodimensional and nanocrystalline TCP....................252
6.4. Other nanodimensional and nanocrystalline calcium
orthophosphates............................................................253
xiv Contents
6.5. Biomimetic construction using nanodimensional
particles.........................................................................257
7. Biomedical Applications of Nanodimensional
and Nanocrystalline Calcium Orthophosphates......................258
7.1. Bone repair....................................................................258
7.2. Nanodimensional and nanocrystalline calcium
orthophosphates and cells..............................................262
7.3. Dental applications.........................................................266
7.4. Other biomedical applications........................................268
8. Non-Biomedical Applications of the Nanodimensional
and Nanocrystalline Calcium Orthophosphates......................276
9. Summary and Perspectives.....................................................276
10. Conclusions.........................................................................280
11. Post-Conclusion Remarks....................................................281
References..................................................................................282
Chapter 8 Nano-Bioceramics as Coatings for
Orthopedic Implants and Scaffolds for
Bone Regeneration...............................................343
Tonßxinß Liu Mohamed N. Rahaman
and B. Sonny Bal
1. Nanotechnology in Orthopedic and Dental Implants.............344
1.1. Nanoscale topography...................................................346
1.2. Nanostructured coatings of bioactive ceramics..............350
1.2.1. Calcium phosphate-based (CaP) coatings............351
1.2.2. Nanocomposite and doped HA coatings.............353
1.2.3. Reinforcement of HA coatings with nanoscale
phases.................................................................356
1.2.4. Non-CaP ceramic coatings..................................358
1.3. Outlook for nanostructured ceramic coatings.................360
2. Three-Dimensional Macroporous Scaffolds
of Nanostructured Bioceramics..............................................360
2.1. Bioactive glass scaffolds..................................................361
2.2. CaP scaffolds..................................................................364
2.3. Surface coating..............................................................367
2.4. Polymer-ceramic nanocomposites...................................369
Contents xv
2.4.1. Nanophase bioactive ceramic coating on
macroporous biopolymer scaffolds.......................370
2.4.2. Organic-inorganic composites.............................371
2.5. Outlook for nanocomposite scaffolds.............................375
References..................................................................................376
Chapter 9 Cell Behavior on Electrospun Scaffolds:
Factors at Play on Nanoscale...............................393
Parthasarathy Madurantakam and Gary Bowlin
1. Introduction..........................................................................394
2. Cell Sensing of the Micro-Environment.................................395
2.1. Cell-biomaterial interface...............................................396
2.1.1. Integrins.............................................................397
2.1.2. Integrin mediated adhesions................................398
2.1.3. Intracellular signaling pathways...........................400
2.2. Electrospinning..............................................................401
2.3. Nano-topologies in electrospun scaffolds........................403
2.3.1. Fiber diameter.....................................................403
2.3.2. Fiber alignment...................................................405
2.3.3. Pore size and porosity.........................................407
3. Biological Response to Electrospun Scaffolds.........................411
4. Physical Substrate for Stem Cell Differentiation.....................412
5. Effect of Fiber Diameter and Scaffold Porosity.......................415
6. Effect of Fiber Alignment......................................................417
7. Effect of Chemically Modified Electrospun Scaffolds..............419
8. Conclusion............................................................................424
References..................................................................................425
Chapter 10 The Convergence of Biomimetic Nanofibers
and Cells for Functional Tissue Formation.......435
Xuening Chen, Licheng Wang
and Hongjun Wang
1. Introduction..........................................................................436
2. Fabrication of Nanofibers with a Diverse Chemistry...............438
2.1. Synthetic polymer fibers.................................................438
xvi Contents
2.1.1. Polycaprolactone.................................................438
2.1.2. Poly(lactic-co-glycolic acid).................................442
2.1.3. Other synthetic polymers.....................................443
2.2. Natural polymer fibers....................................................443
2.2.1. Collagen.............................................................444
2.2.2. Chitosan.............................................................445
2.2.3. Silk fibroin..........................................................446
2.2.4. Other natural polymers.......................................447
2.3. Composite nanofiber......................................................448
2.3.1. Synthetic polymers with natural polymers............448
2.3.2. Polymers with ceramics.......................................450
3. Fiber Dimension and Spatial Arrangement.............................450
3.1. Fiber diameter................................................................450
3.2. Spatial arrangement of electrospun nanofibers................452
4. Cell-Electrospun Fiber Interaction.........................................455
4.1. Cell morphology............................................................455
4.2. Cell migration and proliferation.....................................456
4.3. Cell phenotype...............................................................457
4.4. Underlying mechanism..................................................459
5. Future Perspective and Challenge..........................................460
6. Conclusion............................................................................461
Acknowledgment........................................................................462
References..................................................................................462
Chapter 11 Surface Structure of Nanocomposites and
Its Properties: A Practical Example...................473
Davide Barbieri, Joost D. de Bruijn
and Huipin Tuan
1. The Importance of the Surface in Biomaterials.......................474
2. Nano-Composites with Active Surfaces..................................478
2.1. Synthesis of nano-sized calcium phosphate apatite..........480
2.2. Preparation of composites having various surface
roughness levels.............................................................482
2.3. Characterization of the surface of composite discs
(i.e. roughness and hydrophilicity).................................486
Contents xvii
2.4. In vitro degradation.......................................................489
2.5. In vitro surface mineralization........................................492
2.6. Serum protein adsorption...............................................495
2.7. rhBMP-2 adsorption from enriched culture medium......496
2.8. hBMSCs cell culture......................................................497
2.9. In vivo tissue response....................................................499
3. Discussion..............................................................................501
Acknowledgments.......................................................................507
References..................................................................................508
Index..........................................................................................517
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| spelling | Tissue regeneration where nano-structure meets biology ed. Qing Liu & Hongjun Wang New Jersey [u.a.] World Scientific 2014 XXIII, 521 S. txt rdacontent n rdamedia nc rdacarrier Frontiers in nanobiomedical research 2 Includes bibliographical references and index Tissue Engineering Regeneration Nanostructures Liu, Qing Sonstige oth Frontiers in nanobiomedical research 2 (DE-604)BV040947210 2 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027194539&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Tissue regeneration where nano-structure meets biology Frontiers in nanobiomedical research Tissue Engineering Regeneration Nanostructures |
| title | Tissue regeneration where nano-structure meets biology |
| title_auth | Tissue regeneration where nano-structure meets biology |
| title_exact_search | Tissue regeneration where nano-structure meets biology |
| title_full | Tissue regeneration where nano-structure meets biology ed. Qing Liu & Hongjun Wang |
| title_fullStr | Tissue regeneration where nano-structure meets biology ed. Qing Liu & Hongjun Wang |
| title_full_unstemmed | Tissue regeneration where nano-structure meets biology ed. Qing Liu & Hongjun Wang |
| title_short | Tissue regeneration |
| title_sort | tissue regeneration where nano structure meets biology |
| title_sub | where nano-structure meets biology |
| topic | Tissue Engineering Regeneration Nanostructures |
| topic_facet | Tissue Engineering Regeneration Nanostructures |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027194539&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV040947210 |
| work_keys_str_mv | AT liuqing tissueregenerationwherenanostructuremeetsbiology |