MicroRNAs: Key Regulators of Oncogenesis
Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs play a momentous role in oncogenesis via regulating cell proliferation and apoptosis as...
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Cham [u.a.]
Springer
2014
|
| Schlagworte: | |
| Online-Zugang: | TUM01 UBT01 Volltext |
| Zusammenfassung: | Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs play a momentous role in oncogenesis via regulating cell proliferation and apoptosis as oncogenes or tumour suppressors. Expression signatures of miRNAs offer exciting opportunities for crafting cutting edge strategies in the diagnosis, prognosis, and therapy of cancer. Since miRNAs can function as either oncogenes or tumor suppressor genes in the tortuous route of oncogenesis, the promise represented by using these small RNAs as therapeutic targets presents new perspectives to the landscape of cancer therapy by either inhibiting or augmenting their activity. This book devotes efforts to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of miRNAs found to be associated with cancer pathogenesis and possible mechanisms underlying the substantial roles played by miRNAs in cancer development and progression. Also, it intends to pave the way for readers to gain novel insights into using miRNAs as cancer biomarkers and therapeutic platforms |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9783319037257 |
| DOI: | 10.1007/978-3-319-03725-7 |
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| spelling | MicroRNAs Key Regulators of Oncogenesis Sadegh Babashah, ed. Cham [u.a.] Springer 2014 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs play a momentous role in oncogenesis via regulating cell proliferation and apoptosis as oncogenes or tumour suppressors. Expression signatures of miRNAs offer exciting opportunities for crafting cutting edge strategies in the diagnosis, prognosis, and therapy of cancer. Since miRNAs can function as either oncogenes or tumor suppressor genes in the tortuous route of oncogenesis, the promise represented by using these small RNAs as therapeutic targets presents new perspectives to the landscape of cancer therapy by either inhibiting or augmenting their activity. This book devotes efforts to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of miRNAs found to be associated with cancer pathogenesis and possible mechanisms underlying the substantial roles played by miRNAs in cancer development and progression. Also, it intends to pave the way for readers to gain novel insights into using miRNAs as cancer biomarkers and therapeutic platforms Medizin Medicine Oncology Human genetics Gene expression Medical genetics Drug interactions miRNS (DE-588)7736808-3 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 s miRNS (DE-588)7736808-3 s 1\p DE-604 Babashah, Sadegh Sonstige oth Erscheint auch als Druckausgabe 978-3-319-03724-0 https://doi.org/10.1007/978-3-319-03725-7 Verlag Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | MicroRNAs Key Regulators of Oncogenesis Medizin Medicine Oncology Human genetics Gene expression Medical genetics Drug interactions miRNS (DE-588)7736808-3 gnd Krebs Medizin (DE-588)4073781-0 gnd |
| subject_GND | (DE-588)7736808-3 (DE-588)4073781-0 |
| title | MicroRNAs Key Regulators of Oncogenesis |
| title_auth | MicroRNAs Key Regulators of Oncogenesis |
| title_exact_search | MicroRNAs Key Regulators of Oncogenesis |
| title_full | MicroRNAs Key Regulators of Oncogenesis Sadegh Babashah, ed. |
| title_fullStr | MicroRNAs Key Regulators of Oncogenesis Sadegh Babashah, ed. |
| title_full_unstemmed | MicroRNAs Key Regulators of Oncogenesis Sadegh Babashah, ed. |
| title_short | MicroRNAs |
| title_sort | micrornas key regulators of oncogenesis |
| title_sub | Key Regulators of Oncogenesis |
| topic | Medizin Medicine Oncology Human genetics Gene expression Medical genetics Drug interactions miRNS (DE-588)7736808-3 gnd Krebs Medizin (DE-588)4073781-0 gnd |
| topic_facet | Medizin Medicine Oncology Human genetics Gene expression Medical genetics Drug interactions miRNS Krebs Medizin |
| url | https://doi.org/10.1007/978-3-319-03725-7 |
| work_keys_str_mv | AT babashahsadegh micrornaskeyregulatorsofoncogenesis |