Trichloroethylene: Toxicity and Health Risks:
A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used...
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
London [u.a.]
Springer / Humana Press
2014
|
| Schriftenreihe: | Molecular and Integrative Toxicology
|
| Schlagworte: | |
| Online-Zugang: | TUM01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Zusammenfassung: | A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9781447163114 |
| DOI: | 10.1007/978-1-4471-6311-4 |
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| 520 | 1 | |a A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity | |
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Datensatz im Suchindex
| _version_ | 1804152019251888128 |
|---|---|
| adam_text | TRICHLOROETHYLENE: TOXICITY AND HEALTH RISKS
/
: 2014
TABLE OF CONTENTS / INHALTSVERZEICHNIS
HISTORY OF TCE
TRICHLOROETHYLENE AND AUTOIMMUNITY IN HUMAN AND ANIMAL.-HYPERSENSITIVITY
DERMATITIS AND HEPATITIS
TRICHLOROETHYLENE-INDUCED OXIDATIVE STRESS AND AUTOIMMUNITY.-BRAIN AND
BEHAVIORAL CHANGES IN RODENT MODELS
ROLE OF TRICHLOROETHYLENE IN PARKINSON’S DISEASE
NEUROIMMUNE EFFECTS OF DEVELOPMENTAL TCE EXPOSURE
ENVIRONMENTAL SENSITIVITY TO TRICHLOROETHYLENE (TCE) IN THE DEVELOPING
HEART
TRICHLOROETHYLENE AND CANCER
EPIGENETIC ALTERATIONS DUE TO TRICHLOROETHYLENE
MATHEMATICAL MODELING AND TRICHLOROETHYLENE
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
TRICHLOROETHYLENE: TOXICITY AND HEALTH RISKS
/
: 2014
ABSTRACT / INHALTSTEXT
A COMPREHENSIVE OVERVIEW OF THE EFFECTS OF TRICHLOROETHYLENE TOXICITY
CAUSED BY REAL-LIFE EXPOSURE LEVELS HIGHLIGHTING HOW EXPOSURE TO
TRICHLOROETHYLENE MAY CONTRIBUTE TO THE ETIOLOGY OF SEVERAL IDIOPATHIC
HUMAN DISEASES. DISCUSSION WILL FOCUS ON DIFFERENT KINDS OF MODELING AND
HOW THEY MAY BE USED TO PREDICT FUNCTIONAL CONSEQUENCES AND TO DISSECT
THE CONTRIBUTION OF DIFFERENT MECHANISTIC PATHWAYS, INCLUDING POTENTIAL
MECHANISMS OF ACTION FOR TRICHLOROETHYLENE TOXICITY IN DIFFERENT ORGAN
SYSTEMS. IT WILL EXPLORE THE ROLE OF EPIGENETIC ALTERATIONS IN
TRICHLOROETHYLENE TOXICITY, THIS PROVIDES IMPORTANT MECHANISTIC
INFORMATION AND MAY ALSO PROVIDE THE BASIS FOR INTERVENTION THERAPY.
CHAPTERS WILL ALSO EXPLAIN HOW THE RISKS FROM TRICHLOROETHYLENE EXPOSURE
MAY BE GREATER IN CERTAIN POPULATIONS BASED ON GENETIC PREDISPOSITION,
AGE OF EXPOSURE AND CO-EXPOSURE TO OTHER CHEMICALS WITH CONTRIBUTIONS
FROM INTERNATIONAL EXPERTS IN THE FIELD, TRICHLOROETHYLENE: TOXICITY AND
HEALTH RISKS IS AN ESSENTIAL RESOURCE FOR RESEARCHERS AND CLINICIANS IN
TOXICOLOGY, IMMUNOLOGY, MEDICINE AND PUBLIC HEALTH AS WELL AS INDUSTRY
AND GOVERNMENT REGULATORY SCIENTISTS INVOLVED IN SAFETY AND HEALTH
PROTECTION AND EPIDEMIOLOGISTS, HIGHLIGHTING THE NEED FOR
INTERDISCIPLINARY COOPERATION IN SOLVING ISSUES OF ENVIRONMENTAL
TOXICITY
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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| spelling | Trichloroethylene: Toxicity and Health Risks Kathleen M. Gilbert ; Sarah J. Blossom, ed. London [u.a.] Springer / Humana Press 2014 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Molecular and Integrative Toxicology A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity Medizin Medicine Immunology Toxicology Biochemistry Epidemiology Environmental Medicine Trichlorethylen (DE-588)4186064-0 gnd rswk-swf Toxikologie (DE-588)4060538-3 gnd rswk-swf Trichlorethylen (DE-588)4186064-0 s Toxikologie (DE-588)4060538-3 s DE-604 Gilbert, Kathleen M. Sonstige oth Blossom, Sarah J. Sonstige oth Erscheint auch als Druckausgabe 978-1-4471-6310-7 https://doi.org/10.1007/978-1-4471-6311-4 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027180995&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027180995&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Trichloroethylene: Toxicity and Health Risks Medizin Medicine Immunology Toxicology Biochemistry Epidemiology Environmental Medicine Trichlorethylen (DE-588)4186064-0 gnd Toxikologie (DE-588)4060538-3 gnd |
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| title | Trichloroethylene: Toxicity and Health Risks |
| title_auth | Trichloroethylene: Toxicity and Health Risks |
| title_exact_search | Trichloroethylene: Toxicity and Health Risks |
| title_full | Trichloroethylene: Toxicity and Health Risks Kathleen M. Gilbert ; Sarah J. Blossom, ed. |
| title_fullStr | Trichloroethylene: Toxicity and Health Risks Kathleen M. Gilbert ; Sarah J. Blossom, ed. |
| title_full_unstemmed | Trichloroethylene: Toxicity and Health Risks Kathleen M. Gilbert ; Sarah J. Blossom, ed. |
| title_short | Trichloroethylene: Toxicity and Health Risks |
| title_sort | trichloroethylene toxicity and health risks |
| topic | Medizin Medicine Immunology Toxicology Biochemistry Epidemiology Environmental Medicine Trichlorethylen (DE-588)4186064-0 gnd Toxikologie (DE-588)4060538-3 gnd |
| topic_facet | Medizin Medicine Immunology Toxicology Biochemistry Epidemiology Environmental Medicine Trichlorethylen Toxikologie |
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