Total Synthesis of (±)-Maoecrystal V:

In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel a...

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Bibliographische Detailangaben
1. Verfasser: Gong, Jianxian (VerfasserIn)
Format: Abschlussarbeit Elektronisch E-Book
Sprache:English
Veröffentlicht: Berlin [u.a.] Springer 2014
Schriftenreihe:Springer Theses
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Abstract
Zusammenfassung:In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereoselective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures
Beschreibung:1 Online-Ressource
ISBN:9783642543043
DOI:10.1007/978-3-642-54304-3

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