The human microbiome: ethical, legal and social concerns
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Oxford [u.a.]
Oxford Univ. Press
2013
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Includes index. |
| Beschreibung: | XIV, 266 S. |
| ISBN: | 9780199829415 9780199322152 |
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Datensatz im Suchindex
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|---|---|
| adam_text | CONTENTS
Acknowledgments
xi
Microbiome
Working
Group
Participants
xiii
Introduction: Looking Back and Looking Forward
1
ROSAMOND RHODES
The Project Collaborators
3
Our Method
4
The Scope of this Volume
6
Reading this Book
12
1.
The Human Microbiome: Science, History, and Research
16
LILY E. FRANK, KEITH
BENKOV,
MARTIN
BLASER, KURT HIRSCHHORN,
DANIEL
A. MOROS,
SEAN PHILPOTT, MATTHEW E. RHODES,
RHODA SPERLING
Introduction
16
The Role of Microorganisms in the Environment
19
The Use of Microorganisms in Industry and Food Production
22
The History of Microorganisms in Human Health and Disease
23
The Human Microbiome
28
Human Microbiome Project and the National Institutes of Health
32
Research Tools and Methods
34
Acquisition of the Microbiome
38
Interactions Between the Microbiome and the Host Genome
42
Manipulating the Microbiome for Medical Purposes
45
Conclusion
47
2.
Personal Identity: Our Microbes, Ourselves
55
NADA GLIGOROV,
JODY AZZOUNI,
DOUGLAS P. LACKEY, ARNOLD
ZWEIG
Introduction
55
Personal Identity over Time
56
The Human Microbiome and Numerical Identity
58
The Human Microbiome and Conceptions of Self
61
The Impact of Science on Commonsense Conceptions of Self
66
Conclusion
69
Policy Recommendations
69
îi·
viii Contents
3.
Property and Research on the Human Microbiome
71
ABRAHAM
R
SCHWAB, MARY ANN BAILY, JOSEPH GOLDFARB,
KURT HIRSCHHORN,
ROSAMOND RHODES, BRETT TRUSKO
Four Controversial Cases
71
Introduction
72
Ownership and Property in Philosophy
73
Ownership and Property in the Social Sciences
78
Ownership and Property in the Context of
Biomedical
Research
79
Current Property Structures and Research on the Human Microbiome
81
Patents
83
Copyrights
91
Property Rights and Biological Samples
94
Conclusion
100
Policy Recommendations
101
4.
Privacy, Confidentiality, and New Ways of Knowing More
107
NADA
GLIGOROV, LILY E. FRANK, ABRAHAM
R
SCHWAB, BRETT TRUSKO
Introduction
107
Philosophical Approaches to Privacy
108
Confidentiality
116
Legislations to Protect Medical and Research Information
118
Data Sharing
121
Conclusion
125
Policy Recommendations
126
5.
Research Ethics
128
ROSAMOND RHODES, MARTIN J.
BLASER,
JOSEPH W.
DAUBEN,
LILY E. FRANK,
DANIELA.
MOROS, SEAN
PHILPOTT
Introduction
128
The Landscape of Microbiome Research
130
Historical Development of Research Ethics Regulation and Guidelines
136
Research Ethics and Human Microbiome Research
140
Critical Reflections on the U.S. Framework for Human Subject
Research
142
Implications for the Conduct of Human Subject Microbiome Research
157
Research and Regulation of Probiotics and Phages
164
Conclusion
171
Policy Recommendations
173
6.
Biobanks and the Human Microbiome
182
ABRAHAM
R
SCHWAB, BARBARA BRENNER, JOSEPH GOLDFARB,
ROCHELLE HIRSCHHORN,
SEAN
PHILPOTT
Introduction
182
What Is a Biobank?
182
Contents ix
Human Microbiome Biobanks 185
Ethical,
Legal,
and Social Implications of
Human Microbiome
Biobanks 186
International Biobanks 196
Community
Consultation: A Reasonable Approach to Participatory
Research
198
Discrimination and Other Issues
203
Conclusion
203
Policy Recommendations
204
7.
Public Health and Research on Populations
208
ROSAMOND RHODES,STEFAN BERNARD BAUMRIN, MARTIN J.
BLASER,
WILLIAM J. EARLE, DEBBIE
INDYK, ETHYLIN
WANG JABS,
DANIEL
A. MOROS,
LYNNE
D.
RICHARDSON, HENRY
S.
SACKS
Microbes and Public Health
208
Public Health, Liberty, and Privacy
213
Public Health Functions
214
Public Health Agency Powers
215
Public Health Methods
216
Research Regulations and Public Health Data Gathering
217
Quality Assurance, Quality Improvement, and Surveillance
218
De Minimis
Risk: A Proposal for a New Category of Research Risk
224
Additional Factors in the Ethical Conduct of Population Studies
230
Prevention and Education
231
Cautions for Public Health Policymakers
232
Coda; Further Philosophical Reflections on Public Health
and the Microbiome
236
Policy Recommendations
240
Glossary
247
Index
253
The human microbiome is the bacteria,
viruses, and fungi that cover our slcira. line
our intestines, and flourish in our body
cavities. Work: on. the human microbiome
is
nevŕ.
but it is cjuieldy becoming a
leading area of
oio
me
d
i cal
research. What
scientists are learning about humans and
our mierobiomes could change medical
practice by introducing ne-w treatment
modalities. This
nev*-
knowledge redefines
us as
superorganisms
comprised of
the human body and the collection of
microbes that inhabit it and reveals how
much v*re are a part of our environment
.
The understanding that microbes are not
only beneficial but sometimes necessary
for survival recasts our interaction with
microbes froj3» adversarial to
volume explores some of the science
that
malees
human microbiome research
possible. It then considers
ctiiàcal. legai.
and social concerns raised by microbiome
research. Chapters explore issues related
to personal identity, property rights, and
privacy. The authors reflect on ho-w human
жпісгоїуіошхіе·
research*, challenges reigning
views on public health and research
ethics. They also address the need for
thoughtful policies and procedures to
guide the use of the biobanked human
samples required for
adxaKic-ing;
this
new domain of research.
Ir»
the course
of these explorations, they introduce
examples from the history of
biomedical
science and recent legal cases that shed
light on the issues and
кхх£ож~жхх
the
polàcy
recommendations they offer at the end of
each topic s discussion.
This volume is the product of an Nil
H
Human
МісгоЬіоше
Project
grant. It represents
three vears of conversations focused
on consensus formation by the twenty-
seven members of the interdisciplinarv
Microbiome Working Croup.
ROSAMONO
RHODES,
Pb.D.,
is
Professor* of Medical Education a>2id
Director of
Bioetłiics
Education at
Icahn School of Mledicine at Mount
Sinai. Professor of Philosophy at The
Graduate Center,
CUMY.
and Professor
of Bioethics arid Associate Director
of the Union-Mount Sinai Bioethics
Program.
Sne
writes on a broad array
of issues in bioethics.
NADA
GLIGOROV, Ph.D., is Assistant
Professor of
Medical
Education at
Icaferł
School of Medicine at Mount
Sinai and Assistant Professor* of
Bioetłiics
at the Union-Mount Sinai
Bioethics Program. She is primarily
interested in neuroethics, most
specifically determinism and free
as *rell as the impact of
Ъг&1п
technologies on privacy. She has also
published on personal identity as it
relates to biomedical issues such as
advance directives.
ABRAHAM PAUL SCHWAB, Ph.D..
i*> Assistant Professor of Philosophy at
ΙΐκϋΆΤΊ-Ά
Lniversity-Purdue University
Port Xavne arid an associate faeultv
member
ir*
the Union Mount Sinai
Bioethics
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| spelling | The human microbiome ethical, legal and social concerns ed. by Rosamond Rhodes ... Oxford [u.a.] Oxford Univ. Press 2013 XIV, 266 S. txt rdacontent n rdamedia nc rdacarrier Includes index. Ethik Medizin Recht Medical microbiology Research United States Human body Research Moral and ethical aspects United States Bacterial genomes Research United States Human body Law and legislation United States Medicine Research United States Medizinische Ethik (DE-588)4074672-0 gnd rswk-swf Medizinische Mikrobiologie (DE-588)4038264-3 gnd rswk-swf Gesetzgebung (DE-588)4020682-8 gnd rswk-swf USA USA (DE-588)4078704-7 gnd rswk-swf Medizinische Mikrobiologie (DE-588)4038264-3 s Medizinische Ethik (DE-588)4074672-0 s DE-604 Gesetzgebung (DE-588)4020682-8 s USA (DE-588)4078704-7 g Rhodes, Rosamond (DE-588)1045412139 edt Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027160887&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027160887&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | The human microbiome ethical, legal and social concerns Ethik Medizin Recht Medical microbiology Research United States Human body Research Moral and ethical aspects United States Bacterial genomes Research United States Human body Law and legislation United States Medicine Research United States Medizinische Ethik (DE-588)4074672-0 gnd Medizinische Mikrobiologie (DE-588)4038264-3 gnd Gesetzgebung (DE-588)4020682-8 gnd |
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| title | The human microbiome ethical, legal and social concerns |
| title_auth | The human microbiome ethical, legal and social concerns |
| title_exact_search | The human microbiome ethical, legal and social concerns |
| title_full | The human microbiome ethical, legal and social concerns ed. by Rosamond Rhodes ... |
| title_fullStr | The human microbiome ethical, legal and social concerns ed. by Rosamond Rhodes ... |
| title_full_unstemmed | The human microbiome ethical, legal and social concerns ed. by Rosamond Rhodes ... |
| title_short | The human microbiome |
| title_sort | the human microbiome ethical legal and social concerns |
| title_sub | ethical, legal and social concerns |
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