Design, analysis, and interpretation of genome-wide association scans:
Gespeichert in:
1. Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
New York, NY [u.a.]
Springer
2014
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Schriftenreihe: | Statistics for biology and health
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Schlagworte: | |
Online-Zugang: | BTU01 FRO01 TUM01 UBA01 UBM01 UBT01 UBW01 UPA01 Volltext Inhaltsverzeichnis Abstract |
Beschreibung: | 1 Online-Ressource |
ISBN: | 9781461494423 9781461494430 |
DOI: | 10.1007/978-1-4614-9443-0 |
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Datensatz im Suchindex
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adam_text | DESIGN, ANALYSIS, AND INTERPRETATION OF GENOME-WIDE ASSOCIATION SCANS
/ STRAM, DANIEL O.
: 2014
TABLE OF CONTENTS / INHALTSVERZEICHNIS
INTRODUCTION TO GENOME-WIDE ASSOCIATION STUDIES
TOPICS OF QUANTITATIVE GENETICS
AN INTRODUCTION TO ASSOCIATION STUDIES
CORRECTING FOR HIDDEN POPULATION STRUCTURE IN SINGLE MARKER ASSOCIATION
TESTING AND ESTIMATION
HAPLOTYPE IMPUTATION FOR ASSOCIATION ANALYSIS
SNP IMPUTATION FOR ASSOCIATION STUDIES
DESIGN OF LARGE-SCALE GENETIC ASSOCIATION STUDIES, SAMPLE SIZE AND POWER
POST-GWAS ANALYSES
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
DESIGN, ANALYSIS, AND INTERPRETATION OF GENOME-WIDE ASSOCIATION SCANS
/ STRAM, DANIEL O.
: 2014
ABSTRACT / INHALTSTEXT
THIS BOOK PRESENTS THE STATISTICAL ASPECTS OF DESIGNING, ANALYZING AND
INTERPRETING THE RESULTS OF GENOME-WIDE ASSOCIATION SCANS (GWAS STUDIES)
FOR GENETIC CAUSES OF DISEASE USING UNRELATED SUBJECTS. PARTICULAR
DETAIL IS GIVEN TO THE PRACTICAL ASPECTS OF EMPLOYING THE BIOINFORMATICS
AND DATA HANDLING METHODS NECESSARY TO PREPARE DATA FOR STATISTICAL
ANALYSIS. THE GOAL IN WRITING THIS BOOK IS TO GIVE STATISTICIANS,
EPIDEMIOLOGISTS, AND STUDENTS IN THESE FIELDS THE TOOLS TO DESIGN A
POWERFUL GENOME-WIDE STUDY BASED ON CURRENT TECHNOLOGY. THE OTHER PART
OF THIS IS SHOWING READERS HOW TO CONDUCT ANALYSIS OF THE CREATED STUDY.
DESIGN AND ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES PROVIDES A
COMPENDIUM OF WELL-ESTABLISHED STATISTICAL METHODS BASED UPON SINGLE SNP
ASSOCIATIONS. IT ALSO PROVIDES AN INTRODUCTION TO MORE ADVANCED
STATISTICAL METHODS AND ISSUES. KNOWING THAT TECHNOLOGY, FOR INSTANCE
LARGE SCALE SNP ARRAYS, IS QUICKLY CHANGING, THIS TEXT HAS SIGNIFICANT
LESSONS FOR FUTURE USE WITH SEQUENCING DATA. EMPHASIS ON STATISTICAL
CONCEPTS THAT APPLY TO THE PROBLEM OF FINDING DISEASE ASSOCIATIONS
IRRESPECTIVE OF THE TECHNOLOGY ENSURES ITS FUTURE APPLICATIONS. THE
AUTHOR INCLUDES CURRENT BIOINFORMATICS TOOLS WHILE OUTLINING THE TOOLS
THAT WILL BE REQUIRED FOR USE WITH EXTENSIVE DATABASES FROM FUTURE LARGE
SCALE SEQUENCING PROJECTS. THE AUTHOR INCLUDES CURRENT BIOINFORMATICS
TOOLS WHILE OUTLINING ADDITIONAL ISSUES AND NEEDS ARISING FROM THE
EXTENSIVE DATABASES FROM FUTURE LARGE SCALE SEQUENCING PROJECTS
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
any_adam_object | 1 |
author | Stram, Daniel O. |
author_GND | (DE-588)170890082 |
author_facet | Stram, Daniel O. |
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author_sort | Stram, Daniel O. |
author_variant | d o s do dos |
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collection | ZDB-2-SMA |
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discipline | Mathematik Medizin |
doi_str_mv | 10.1007/978-1-4614-9443-0 |
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spelling | Stram, Daniel O. Verfasser (DE-588)170890082 aut Design, analysis, and interpretation of genome-wide association scans Daniel O. Stram New York, NY [u.a.] Springer 2014 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Statistics for biology and health Genkartierung (DE-588)4123274-4 gnd rswk-swf Genkartierung (DE-588)4123274-4 s 1\p DE-604 https://doi.org/10.1007/978-1-4614-9443-0 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027069060&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027069060&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Stram, Daniel O. Design, analysis, and interpretation of genome-wide association scans Genkartierung (DE-588)4123274-4 gnd |
subject_GND | (DE-588)4123274-4 |
title | Design, analysis, and interpretation of genome-wide association scans |
title_auth | Design, analysis, and interpretation of genome-wide association scans |
title_exact_search | Design, analysis, and interpretation of genome-wide association scans |
title_full | Design, analysis, and interpretation of genome-wide association scans Daniel O. Stram |
title_fullStr | Design, analysis, and interpretation of genome-wide association scans Daniel O. Stram |
title_full_unstemmed | Design, analysis, and interpretation of genome-wide association scans Daniel O. Stram |
title_short | Design, analysis, and interpretation of genome-wide association scans |
title_sort | design analysis and interpretation of genome wide association scans |
topic | Genkartierung (DE-588)4123274-4 gnd |
topic_facet | Genkartierung |
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