Verfügbarkeit: Proteases in Health and Disease

Proteases in Health and Disease:

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Bibliographische Detailangaben
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	New York, NY [u.a.] Springer 2013
Schriftenreihe:	Advances in Biochemistry in Health and Disease 7
Schlagworte:	Biowissenschaften Life sciences Biochemistry Proteomics Cytology Life Sciences
Online-Zugang:	FAN01 UBT01 Volltext Inhaltsverzeichnis Abstract
Beschreibung:	1 Online-Ressource
ISBN:	9781461492337
DOI:	10.1007/978-1-4614-9233-7

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MARC


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Datensatz im Suchindex

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adam_text	PROTEASES IN HEALTH AND DISEASE / : 2013 TABLE OF CONTENTS / INHALTSVERZEICHNIS PART A: MOLECULAR AND BIOCHEMICAL ASPECTS OF PROTEASES 1. AN OVERVIEW OF ENDOPLASMIC RETICULUM CALPAIN SYSTEM 2. MITOCHONDRIAL CALPAINS: WHO, WHAT, WHERE, WHEN AND WHY? 3. ROLE OF CALPAINS IN CALMODULIN REGULATED SYSTEMS 4. EXERCISE AND MATRIX METALLOPROTEASES: A BRIEF OVERVIEW 5. REGULATION OF CHONDROCYTE MATRIX METALLOPROTEINASE GENE EXPRESSION 6. MICROBIAL SOURCE OF FIBRINOLYTIC PROTEASE AND ITS BIOTECHNOLOGICAL POTENTIAL 7. ASPARTIC PROTEOLYTIC INHIBITORS INDUCE CELLULAR AND BIOCHEMICAL ALTERATIONS IN FUNGAL CELLS 8. CYSTEINE PROTEASES OF HUMAN MALARIA PARASITES 9. PROTEASES AS VIRULENCE FACTORS IN LEISHMANIA: FOCUS ON SERINE PROTEASES AS POSSIBLE THERAPEUTIC TARGETS 10. AN UPDATED INVENTORY ON PROPERTIES, PATHOPHYSIOLOGY AND THERAPEUTIC POTENTIAL OF SNAKE VENOM THROMBIN-LIKE PROTEASES 11. MACROCYCLIC PROTEASE INHIBITORS CONSTRAINED INTO A Β-STRAND GEOMETRY PART B: INVOLVEMENT OF PROTEASES IN DISEASE PROCESSES 12. REGULATION OF MT1-MMP ACTIVATION AND ITS RELEVANCE TO DISEASE PROCESSES 13. ROLE OF PROTEASES DURING INTRA-ERYTHROCYTIC DEVELOPMENTAL CYCLE OF HUMAN MALARIA PARASITE PLASMODIUM FALCIPARUM 14. PROTEASES IN VIBRIO CHOLERAE AND THEIR ROLE IN PATHOGENESIS 15. ADAMTS13: THE VON WILLEBRAND FACTOR CLEAVING PROTEASE AND ITS ROLE IN THROMBOTIC THROMBOCYTOPENIC PURPURA 16. ROLE OF PROTEASES AND THEIR TISSUE INHIBITORS IN PREGNANCY OUTCOME 17. MATRIX METALLOPROTEINASES IN BONE HEALTH AND DISEASE 18. ESCALATED EXPRESSION OF MATRIX METALLOPROTEINASES IN OSTEOARTHRITIS 19. ROLE OF PROTEASES IN AUTISM SPECTRUM DISORDER 20. ROLE OF PROTEASES IN THE MANAGEMENT OF HEPATITIS C VIRUS 21. ROLE OF PROTEASE IN INFLAMMATORY LUNG DISEASES 22. INVOLVEMENT OF SOME PROTEOLYTIC ENZYMES IN CARDIAC DYSFUNCTION DUE TO ISCHEMIA-REPERFUSION INJURY DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT. PROTEASES IN HEALTH AND DISEASE / : 2013 ABSTRACT / INHALTSTEXT PROTEASES FORM ONE OF THE LARGEST AND MOST DIVERSE FAMILIES OF ENZYMES KNOWN. ONCE CONSIDERED PRIMARILY AS “ENZYMES OF DIGESTION,” IT IS NOW CLEAR THAT PROTEASES ARE INVOLVED IN EVERY ASPECT OF CELLULAR FUNCTION. MEMBERS OF THE DIVERSE FAMILIES OF PROTEASES ACT TO PROMOTE CELLULAR PROTEOLYSIS FOUND IN NATURE, AND THEIR DEREGULATION MAY RESULT IN DIFFERENT PATHOPHYSIOLOGICAL CONDITIONS, SUCH AS TUMOR PROGRESSION, VASCULAR REMODELING, ATHEROSCLEROTIC PLAQUE PROGRESSION, ULCER, RHEUMATOID ARTHRITIS, AND ALZHEIMER’S DISEASE. MANY MICRO-ORGANISMS REQUIRE PROTEASES FOR REPLICATION OR USE PROTEASES AS VIRULENCE FACTORS, WHICH HAVE FACILITATED THE DEVELOPMENT OF PROTEASE-TARGETED THERAPIES FOR A VARIETY OF PARASITIC DISEASES. PROTEASES IN HEALTH AND DISEASE REPRESENTS A COMPREHENSIVE OVERVIEW OF THE FASCINATING FIELD OF PROTEASES BY VARIOUS RENOWNED EXPERTS, AND FOCUSES ON THE RECENTLY ELUCIDATED FUNCTIONS OF COMPLEX PROTEOLYTIC SYSTEMS IN PHYSIOLOGY AND PATHOPHYSIOLOGY.PART A, MOLECULAR AND BIOCHEMICAL ASPECTS OF PROTEASES, ILLUSTRATES SOME OF THE MAJOR PROTEASES, SUCH AS CALPAINS, MATRIX METALLOPROTEASES, FIBRINOLYTIC SERINE PROTEASES, AND ASPARTIC PROTEASES, WHICH PLAY A SIGNIFICANT ROLE IN A VARIETY OF PATHOLOGIES AND MAY BE A TARGET FOR THERAPY EITHER BY THEIR UP REGULATION OR DOWN REGULATION. PART B, INVOLVEMENT OF PROTEASES IN DISEASES PROCESSES, DEALS WITH THE FUNCTIONAL ROLES OF THE INDIVIDUAL PROTEASES IN THE PROGRESSION OF DISEASES SUCH AS CARDIOVASCULAR AND INFLAMMATORY LUNG DISEASE, MALARIA, CHOLERA, AUTISM SPECTRUM DISORDER, HEPATITIS, AND ISCHEMIA-REPERFUSION INJURY INDUCED CARDIAC DISEASES. WITH THIS MULTI-DISCIPLINARY SCOPE, THE BOOK BRIDGES THE GAP BETWEEN FUNDAMENTAL RESEARCH AND BIOMEDICAL AND PHARMACEUTICAL APPLICATIONS, MAKING THIS A THOUGHT-PROVOKING READING FOR BASIC AND APPLIED SCIENTISTS ENGAGED IN BIOMEDICAL RESEARCH. ABOUT THE EDITORS: DR.SAJAL CHAKRABORTI IS A SENIOR PROFESSOR OF BIOCHEMISTRY AT THE UNIVERSITY OF KALYANI, WEST BENGAL, INDIA. HIS RESEARCH COVERS THE ROLE OF PROTEASES IN REGULATING PULMONARY VASCULAR TONE UNDER OXIDANT- AND CALCIUM-SIGNALING PHENOMENA. HE HAS BEEN ENGAGED IN TEACHING AND RESEARCH IN BIOCHEMISTRY FOR THE PAST 35 YEARS. DR. NARANJAN DHALLA IS A DISTINGUISHED PROFESSOR AT THE UNIVERSITY OF MANITOBA, WINNIPEG, CANADA. HIS EXPERTISE INCLUDES THE SUBCELLULAR AND MOLECULAR BASIS OF HEART FUNCTION IN HEALTH AND DISEASE. HE HAS BEEN ENGAGED IN MULTIDISCIPLINARY RESEARCH AND EDUCATION FOR PROMOTING THE SCIENTIFIC BASIS OF CARDIOLOGY, AS WELL AS TRAINING OF PROFESSIONAL MANPOWER FOR COMBATING HEART DISEASE FOR OVER 40 YEARS. DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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spelling	Proteases in Health and Disease Sajal Chakraborti ; Naranjan S. Dhalla, ed. New York, NY [u.a.] Springer 2013 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Advances in Biochemistry in Health and Disease 7 Biowissenschaften Life sciences Biochemistry Proteomics Cytology Life Sciences Chakraborti, Sajal Sonstige oth Dhalla, Naranjan S. 1936- Sonstige (DE-588)104116595 oth Erscheint auch als Druckausgabe 978-1-4614-9232-0 Advances in Biochemistry in Health and Disease 7 (DE-604)BV022371875 7 https://doi.org/10.1007/978-1-4614-9233-7 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027002911&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027002911&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract
spellingShingle	Proteases in Health and Disease Advances in Biochemistry in Health and Disease Biowissenschaften Life sciences Biochemistry Proteomics Cytology Life Sciences
title	Proteases in Health and Disease
title_auth	Proteases in Health and Disease
title_exact_search	Proteases in Health and Disease
title_full	Proteases in Health and Disease Sajal Chakraborti ; Naranjan S. Dhalla, ed.
title_fullStr	Proteases in Health and Disease Sajal Chakraborti ; Naranjan S. Dhalla, ed.
title_full_unstemmed	Proteases in Health and Disease Sajal Chakraborti ; Naranjan S. Dhalla, ed.
title_short	Proteases in Health and Disease
title_sort	proteases in health and disease
topic	Biowissenschaften Life sciences Biochemistry Proteomics Cytology Life Sciences
topic_facet	Biowissenschaften Life sciences Biochemistry Proteomics Cytology Life Sciences
url	https://doi.org/10.1007/978-1-4614-9233-7 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027002911&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=027002911&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA
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work_keys_str_mv	AT chakrabortisajal proteasesinhealthanddisease AT dhallanaranjans proteasesinhealthanddisease

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