Holdings: Study of seed-based microRNA targeting in mammals

Study of seed-based microRNA targeting in mammals:

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Bibliographic Details
Main Author:	Büttner, Florian (Author)
Format:	Thesis Book
Language:	English
Published:	2013
Subjects:	Hochschulschrift
Online Access:	Volltext https://nbn-resolving.org/urn:nbn:de:bvb:91-diss-20131122-1171181-0-3 Inhaltsverzeichnis
Physical Description:	XVIII, 119 S. Ill., graph. Darst.

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MARC


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Record in the Search Index

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adam_text	2.1 LIN-4-LIN-14 DUPLEX 6 2.2 RELATIONSHIP BETWEEN MRNA AND PROTEIN ABUNDANCE 9 2.3 EFFECT OF MIRNA-MEDIATED REGULATION ON PROTEIN ABUNDANCE .... 11 2.4 CIRCULAR MRNA 18 2.5 TEMPORAL ORDER OF MIRNA-MEDIATED GENE SILENCING 20 3.1 SCHEMATIC REPRESENTATION OF A MIRNA TARGET SITE 24 3.2 SET OF CLASSICAL SEED TYPES 26 3.3 CHARACTETISTICS OF CLASSICAL SEED TYPES 27 3.4 DIFFERENT EFFICACY OF ORF AND 3 UTR TARGETING 31 3.5 CROSS-TALK BETWEEN CERNAS 33 3.6 CLIP APPROACHES 35 3.7 POSITIONAL FREQUENCIES OF TARGET SITE STARTS WITHIN CCRS 40 3.8 MINIMAL AND SUFIICIENT SET OF SEED TYPES ACCORDING TO [1] 44 3.9 TRANSCRIPT DESTABILIZATION THROUGH THE 3 UTR 46 3.10 PREDICTIVE POWER OF SEED TYPES 47 3.11 TRANSCRIPT DESTABILIZATION THROUGH THE CODING REGION 49 3.12 SEED TYPE PREFERENCES OF MIRNAS (3 UTR) 51 3.13 SEED TYPE PREFERENCES OF MIRNAS (CODING REGION) 52 3.14 CONSERVATION OF CCRS IN THE 3 UTR 54 3.15 CONSERVATION OF FUNCTIONAL SITES IN THE 3 UTR 55 3.16 PREDICTIVE POWER AFTER REMOVING NON-CONSERVED SITES 57 3.17 CONSERVATION OF FUNCTIONAL SITES IN THE CODING REGION 58 3.18 OVERLAP BETWEEN SEED TYPE SETS . 63 3.19 COMPARISON OF SEED TYPE DISTRIBUTIONS . . . 63 3.20 BACKGROUND CONSERVATION 64 4.1 LEVELS OF EVALUATION 68 4.2 SENSITIVITY OF 3 UTR PREDICTIONS PER SEED TYPE 79 4.3 SENSITIVITY OF ORF PREDICTIONS PER SEED TYPE 81 4.4 DIFFERENT SCORING SYSTEMS 83 4.5 PRECISION-SENSITIVITY CURVES 85 XIII HTTP://D-NB.INFO/1048370682 LIST OF FIGURES 4.6 PRECISION GAIN 86 4.7 INTERSECTION OF PREDICTION RESULT SETS 88 4.8 SENSITIVITY OF THE NAIVE APPROACH PER SEED TYPE 92 4.9 TARGET SITE SCORE DISTRIBUTION PER SEED TYPE (3 UTR) 93 4.10 TARGET SITE SCORE DISTRIBUTION PER SEED TYPE (CODING REGION) 93 5.1 TARGET SITE STARTS DOWNSTREAM OF THE T/C MUTATION 96 5.2 FRAME-DEPENDENT SITE CONSERVATION WITHIN CCRS 97 5.3 REPRESSION OF LRRK2 MRNA EXPRESSION 99
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language	English
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spelling	Büttner, Florian Verfasser aut Study of seed-based microRNA targeting in mammals Florian A. Büttner 2013 XVIII, 119 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier München, Techn. Univ., Diss., 2013 Zsfassung in dt. Sprache (DE-588)4113937-9 Hochschulschrift gnd-content Erscheint auch als Online-Ausgabe urn:nbn:de:bvb:91-diss-20131122-1171181-0-3 http://mediatum.ub.tum.de/node?id=1171181 Verlag kostenfrei Volltext https://nbn-resolving.org/urn:nbn:de:bvb:91-diss-20131122-1171181-0-3 Resolving-System DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026997276&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Büttner, Florian Study of seed-based microRNA targeting in mammals
subject_GND	(DE-588)4113937-9
title	Study of seed-based microRNA targeting in mammals
title_auth	Study of seed-based microRNA targeting in mammals
title_exact_search	Study of seed-based microRNA targeting in mammals
title_full	Study of seed-based microRNA targeting in mammals Florian A. Büttner
title_fullStr	Study of seed-based microRNA targeting in mammals Florian A. Büttner
title_full_unstemmed	Study of seed-based microRNA targeting in mammals Florian A. Büttner
title_short	Study of seed-based microRNA targeting in mammals
title_sort	study of seed based microrna targeting in mammals
topic_facet	Hochschulschrift
url	http://mediatum.ub.tum.de/node?id=1171181 https://nbn-resolving.org/urn:nbn:de:bvb:91-diss-20131122-1171181-0-3 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026997276&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT buttnerflorian studyofseedbasedmicrornatargetinginmammals

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