Development and characterization of PEDOT-CNT microelectrode arrays for advanced neuronal recording, stimulation and sensing:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
Uelvesbüll
Der Andere Verlag
2013
|
| Schriftenreihe: | NMI results
3 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 129, XXII S. |
| ISBN: | 9783862473786 |
Internformat
MARC
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Datensatz im Suchindex
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| adam_text | CONTENTS
CONTENTS
CONTENTS 1
1 ABSTRACT 4
2 ZUSAMMENFASSUNG 6
3 INTRODUCTION 9
3.1 MOTIVATION 9
3.2 AIM AND OUTLINE 9
4 FUNDAMENTALS AND STATE OF THE ART 11
4.1 ELECTROPHYSIOLOGY WITH MICROELECTRODE ARRAYS 11
4.1.1 NEUROTRANSMITTER SENSING 14
4.2 CONDUCTING POLYMERS 17
4.2.1 CONDUCTING POLYMERS IN NEURONAL INTERFACES 20
4.3 CARBON NANOTUBES 23
4.3.1 CNTS IN NEUROTECHNOLOGY 26
4.4 ELECTROCHEMICAL METHODS 28
4.4.1 ELECTROPOLYMERIZATION 28
4.4.2 CYCLIC VOLTAMMETRY 30
4.4.3 IMPEDANCE SPECTROSCOPY 37
4.4.4 CHARGE TRANSFER BY VOLTAGE PULSING 44
4.4.5 SQUARE WAVE VOLTAMMETRY 46
4.5 SPECTROSCOPY AND SURFACE ANALYTICS 49
4.5.1 UV-VIS SPECTROSCOPY 49
4.5.2 SCANNING ELECTRON MICROSCOPY (SEM) AND FOCUSED ION BEAM (FIB) 49
4.5.3 X-RAY PHOTOELECTRON SPECTROSCOPY (XPS) 51
4.5.4 RAMAN SPECTROSCOPY 54
4.5.5 PROFILOMETRY 56
5 MATERIALS AND METHODS 57
5.1 DEVELOPMENT OF PEDOT-CNT MICROELECTRODES 57
5.1.1 CNT SUSPENSION 57
5.1.2 UV-VIS SPECTROSCOPY 57
5.1.3 PRETREATMENT OF GOLD ELECTRODES 58
5.1.4 ELECTROPOLYMERIZATION ON MEA 58
1
HTTP://D-NB.INFO/1043772928
CONTENTS
5.1.5 SURFACE ANALYTICS 58
LIGHT MICROSCOPY 58
SCANNING ELECTRON MICROSCOPY (SEM) AND FOCUSED ION BEAM (FIB) 58
PROFILOMETRY 58
RAMAN SPECTROSCOPY 58
X-RAY PHOTOELECTRON SPECTROSCOPY (XPS) 59
5.1.6 STABILITY TESTING 59
5.1.7 ELECTROCHEMICAL CHARACTERIZATION 59
CYCLIC VOLTAMMETRY 59
IMPEDANCE SPECTROSCOPY 60
VOLTAGE PULSING 60
5.2 ELECTROPHYSIOLOGICAL APPLICATION OF PEDOT-CNT MEAS 60
5.2.1 PREPARATION FOR CELL CULTURE 60
5.2.2 RECORDING FROM AND STIMULATION OF EXCITABLE CELLS 60
CARDIOMYOCYTES 60
SENSORY NEURONS 61
CORTICAL NETWORKS 61
5.2.3 NEUROTRANSMITTER SENSING USING SQUARE WAVE VOLTAMMETRY 62
6 RESULTS AND DISCUSSION 63
6.1 DEVELOPMENT OF PEDOT-CNT MICROELECTRODES 63
6.1.1 AQUEOUS SUSPENSION OF CNT 63
6.1.2 DEPOSITION OF PEDOT-CNT ON GOLD MICROELECTRODES 65
PRETREATMENT OF GOLD ELECTRODES 65
ELECTROPOLYMERIZATION 67
6.1.3 MORPHOLOGICAL CHARACTERIZATION 68
6.1.4 RAMAN SPECTROSCOPY 71
6.1.5 INTERFACE CHARACTERIZATION BY XPS 74
6.1.6 ADHESION 78
6.1.7 ELECTROCHEMICAL CHARACTERIZATION 80
CYCLIC VOLTAMMETRY 80
IMPEDANCE SPECTROSCOPY 83
CHARGE TRANSFER BY VOLTAGE PULSING 92
6.1.8 TRANSFER TO OTHER SUBSTRATES 97
2
CONTENTS
6.1.9 SUMMARY OF CHAPTER 6.1 98
6.2 ELECTROPHYSIOLOGICAL APPLICATION OF PEDOT-CNT MICROELECTRODES 100
6.2.1 STABILITY TOWARDS STANDARD CELL CULTURE PROCEDURES 100
6.2.2 RECORDING FROM EXCITABLE CELLS 101
CARDIOMYOCYTES 101
SENSORY NEURONS 103
CORTICAL NETWORKS 107
6.2.3 STIMULATION OF EXCITABLE CELLS 109
CARDIOMYOCYTES 109
6.2.4 NEUROTRANSMITTER SENSING 112
SENSITIVITY 113
SELECTIVITY 115
THE RELATION OF SELECTIVITY AND PH 118
OTHER NEUROTRANSMITTERS 121
REUSABILITY OF ELECTRODES FOR SENSING 125
6.2.5 SUMMARY OF CHAPTER 6.2 126
7 CONCLUSION AND OUTLOOK 128
8 APPENDIX I
8.1 ABBREVIATIONS HI
8.2 LIST OF SCHEMATA IV
8.3 LIST OF FIGURES V
8.4 LIST OF TABLES IX
8.5 CURRICULUM VITAE X
8.6 PUBLICATIONS XI
8.7 REFERENCES XIV
3
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| indexdate | 2024-07-10T00:55:42Z |
| institution | BVB |
| isbn | 9783862473786 |
| language | English |
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| physical | 129, XXII S. |
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| spelling | Samba, Ramona Verfasser (DE-588)1041726104 aut Development and characterization of PEDOT-CNT microelectrode arrays for advanced neuronal recording, stimulation and sensing Ramona Samba Uelvesbüll Der Andere Verlag 2013 129, XXII S. txt rdacontent n rdamedia nc rdacarrier NMI results 3 Zugl.: Tübingen, Univ., Diss., 2013 Polyethylendioxythiophen Poly-3,4-Ethylendioxythiophen (DE-588)4758772-6 gnd rswk-swf Mikroelektrode (DE-588)4192623-7 gnd rswk-swf Kohlenstoff-Nanoröhre (DE-588)4581365-6 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Mikroelektrode (DE-588)4192623-7 s Polyethylendioxythiophen Poly-3,4-Ethylendioxythiophen (DE-588)4758772-6 s Kohlenstoff-Nanoröhre (DE-588)4581365-6 s DE-604 NMI results 3 (DE-604)BV041392888 3 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026840632&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Samba, Ramona Development and characterization of PEDOT-CNT microelectrode arrays for advanced neuronal recording, stimulation and sensing NMI results Polyethylendioxythiophen Poly-3,4-Ethylendioxythiophen (DE-588)4758772-6 gnd Mikroelektrode (DE-588)4192623-7 gnd Kohlenstoff-Nanoröhre (DE-588)4581365-6 gnd |
| subject_GND | (DE-588)4758772-6 (DE-588)4192623-7 (DE-588)4581365-6 (DE-588)4113937-9 |
| title | Development and characterization of PEDOT-CNT microelectrode arrays for advanced neuronal recording, stimulation and sensing |
| title_auth | Development and characterization of PEDOT-CNT microelectrode arrays for advanced neuronal recording, stimulation and sensing |
| title_exact_search | Development and characterization of PEDOT-CNT microelectrode arrays for advanced neuronal recording, stimulation and sensing |
| title_full | Development and characterization of PEDOT-CNT microelectrode arrays for advanced neuronal recording, stimulation and sensing Ramona Samba |
| title_fullStr | Development and characterization of PEDOT-CNT microelectrode arrays for advanced neuronal recording, stimulation and sensing Ramona Samba |
| title_full_unstemmed | Development and characterization of PEDOT-CNT microelectrode arrays for advanced neuronal recording, stimulation and sensing Ramona Samba |
| title_short | Development and characterization of PEDOT-CNT microelectrode arrays for advanced neuronal recording, stimulation and sensing |
| title_sort | development and characterization of pedot cnt microelectrode arrays for advanced neuronal recording stimulation and sensing |
| topic | Polyethylendioxythiophen Poly-3,4-Ethylendioxythiophen (DE-588)4758772-6 gnd Mikroelektrode (DE-588)4192623-7 gnd Kohlenstoff-Nanoröhre (DE-588)4581365-6 gnd |
| topic_facet | Polyethylendioxythiophen Poly-3,4-Ethylendioxythiophen Mikroelektrode Kohlenstoff-Nanoröhre Hochschulschrift |
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