Basic and applied bone biology:
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
Amsterdam [u.a.]
Elsevier
2014
|
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XV, 373 S. Ill., graph. Darst. 28 cm |
ISBN: | 9780124160156 0124160158 |
Internformat
MARC
LEADER | 00000nam a22000002c 4500 | ||
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245 | 1 | 0 | |a Basic and applied bone biology |c ed. by David B. Burr; Matthew R. Allen |
264 | 1 | |a Amsterdam [u.a.] |b Elsevier |c 2014 | |
300 | |a XV, 373 S. |b Ill., graph. Darst. |c 28 cm | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
650 | 4 | |a Bone | |
650 | 0 | 7 | |a Knochenstoffwechsel |0 (DE-588)4216200-2 |2 gnd |9 rswk-swf |
655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
689 | 0 | 0 | |a Knochenstoffwechsel |0 (DE-588)4216200-2 |D s |
689 | 0 | |5 DE-604 | |
700 | 1 | |a Burr, David B. |e Sonstige |0 (DE-588)1044624639 |4 oth | |
700 | 1 | |a Allen, M. R. |e Sonstige |4 oth | |
856 | 4 | 2 | |m Digitalisierung UB Regensburg - ADAM Catalogue Enrichment |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026816879&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
999 | |a oai:aleph.bib-bvb.de:BVB01-026816879 |
Datensatz im Suchindex
_version_ | 1804151457521336320 |
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adam_text | Contents
Preface
xi
Acknowledgements
xiii
List of Contributors
xv
1
BASIC BONE BIOLOGY AND
PHYSIOLOGY
1.
Bone Morphology and Organization
3
DAVID B. RURR AND OZAN AKKUS
The Functions of Bone
3
Bone is Organized as a Multiscale Material
4
Bone Composition
5
The Nanoscale Organization of Bone
5
The Microstructural Organization of Bone
12
The Macroscopic Organization of Bone
16
The Blood Supply and
Innervation
of Bone
20
Bone Fluid Compartments
21
Bone Mass and Bone Quality
21
Suggested Readings
24
2.
Bone Cells
27
TERESITA
BELLIDO,
LILIAN I. PLOTKIN AND ANGELA BRUZZANIT1
Osteoclasts
27
Osteoblasts
34
Osteocytes
38
Suggested Readings
45
V Local Regulation of Bone Cell Function
47
LILIAN I. PLOTKIN AND NICOLETTA
BIVI
Overview of Cytokines and Growth Factors and their
Receptors
47
Local Factors that Regulate Osteoclast and Osteoblast
Differentiation and Function
49
Factors that Regulate Osteoclast Differentiation and
Function
49
Factors that Affect Osteoblast Differentiation and
Function
51
Local Factors that Affect Both Osteoclasts and
Osteoblasts
59
Regulation of Bone Cell Differentiation and Function
Through Cell-Cell Contact
66
Local Angiogenic Factors that Regulate Bone Cell
Activity
69
Cell Surface Attachment Molecules
70
Suggested Readings
72
4.
Bone Modeling and Remodeling
75
MATTHEW R. ALLEN AND DAVID B. BURR
Skeletal Development
75
Bone Modeling
79
Bone Remodeling
81
Bone Repair
86
Effects of Modeling and Remodeling on Bone Structure
and Material Properties
87
Laboratory Assessment of Modeling and
Remodeling
88
Suggested Readings
90
ASSESSMENT OF BONE
STRUCTURE AND FUNCTION
5.
Skeletal Imaging
93
MATTHEW R. ALLEN AND KELLY KROHN
Radiography
93
Absorptiometry (Photon and X-Ray)
96
Computed Tomography
100
Magnetic Resonance Imaging
105
Positron Emission Tomography
108
Ultrasound
110
Suggested Readings
113
·■
Skeletal Hard Tissue Biomechanics
115
JOSEPH M. WALLACE
Introduction to Basic Bone Structure and
Function
115
Fundamentals of Solid Mechanics
116
Factors Contributing to Whole Bone Mechanical
Properties
124
Suggested Readings
129
VIU
CONTENTS
7.
Techniques in Histomorphometry
131
MATTHEW
R.
ALLEN AND DAVID
B. RURR
Histologie
Specimens
131
Histomorphometric
Analysis
135
Assumptions and
Technical
Aspects
142
Histologie Features
of Disease and Treatment
142
Suggested Readings
147
8.
Skeletal Genetics
149
KENNETH E. WHITE. DANIEL L.
KOLLER
AND TIM CORBIN
Simple and Complex Traits
149
Transgenic Technology and the Creation of Novel
Research Models
154
Transgenic Animals and Bone Biology
165
Suggested Readings
170
SKELETAL ADAPTATION
νλ
Mechanical Adaptation
175
ALEXANDER
G
ROBLING, ROBYN K.
FUCHS
AND DAVID B. BURR
Wolff s Law—A Historical Perspective
175
Components of Strain that May be Osteogenic
176
Animal Models of Skeletal Mechanotransduction
178
Rules for Bone Adaptation
181
The Mechanostat
184
Cell Sensitivity and Refractory Periods
186
A Test of Wolff s Law
187
Mechanotransduction on a Smaller Scale: Cell Types
and their Environment
188
Fluid Flow in Bone Tissue has Manifold Cellular
Effects
189
Cellular Deformation and Stimulation
191
What is the Mechanoreceptor?
192
Coordinating the Biochemical Response to Mechanical
Stimulation
195
Clinical Implications: Reaping the Benefits of Mechanical
Loading Effects to Improve Skeletal Health
197
Important Features of Exercise Regimens Designed to
Influence Skeletal Adaptation
197
Skeletal Benefit of Exercise During Infancy and
Childhood
200
Skeletal Response to Exercise in Adulthood
202
Suggested Readings
203
;
Λ
Fracture Healing
205
JiLIANG
LI ANP DAYIP
L.
ЅТОсГМ
Introduction
205
Types of Bone Fracture
205
Primary and Secondary Repair Mechanisms
206
Stages of Fracture Repair
206
Assessment of Fracture Healing
210
Cellular Events of Fracture Repair
211
Molecular Regulation of Chondrogenesis and
Osteogenesis During Fracture Repair
212
Local Regulation of Fracture Repair
214
Systemic Factors in Fracture Repair
217
Effects of Osteoporosis Drags on Fracture
Healing
220
Effects of Mechanical and Electrical Stimulation on
Fracture Repair
221
Suggested Readings
223
11.
Craniofacial Biology, Orthodontics, and
Implants
225
TIEN-MIN GABRIEL
CHU,
SEAN SHIH-YAO LIU AND WILLIAM
J. BABLER
Craniofacial Skeleton
225
Orthodontic Tooth Movement
233
Suture Expansion
235
Implants
237
Suggested Readings
242
HORMONAL AND METABOLIC
EFFECTS ON BONE
11.
Skeletal Growth and Development
245
CONNIE M. WEAVER AND ROBYN K.
FUCHS
Prenatal
245
Childhood
248
Development of Peak Bone Mass
250
Regulators of Growth
252
Catch-Up Growth
255
Fracture Risk in Children
256
Suggested Readings
260
11
Calcium and Phosphate: Hormonal Regulation
and Metabolism
261
LINDA A. DIMEGLIO AND ERIK A. IMEL
Interplay Among Organ Systems Regulates Calcium and
Phosphorus Metabolism
261
Regulation of Whole Body Calcium Metabolism
265
Hormones Controlling Calcium Metabolism
269
Regulation of Whole Body Phosphate
Metabolism
277
Suggested Readings
282
CONTENTS
ЇХ
14.
Nutrition
283
CONNIE
M.
WEAVER AND KATHLEEN
M.
HILL GALLANT
Macro- and Micronu
trient
Roles in Bone Health
283
When and How Nutrients Influence Bone Mass
287
Perturbing Calcium Metabolism
288
Whole Diet Matters
289
Dietary Bioactives and their
Mechanisms
292
Effects of Obesity and Weight
Loss on Bone
292
Correcting Nutrient Deficiencies Versus
Optimizing Intakes
295
Challenges for Studying Nutrient Interventions
295
Suggested Readings
297
15.
Hormonal Effects on Bone Cells
299
TERESITA
BELLIDO
AND KATHLEEN M. HILL GALLANT
Introduction: Direct Versus Indirect Effects
of Hormones on Bone Cells
299
Parathyroid Hormone
299
Sex Steroids
302
Glucocorticoids
305
Thyroid Hormone
307
Somatotropin/Growth Hormone
308
Insulin
310
1,25-Dihydroxyvitamin D^
311
Leptin
312
Suggested Readings
313
SKELETAL DISEASE AND
TREATMENT
Metabolic Bone Diseases
317
ERIK A. IMEL, LINDA A. DIMEGLIO AND DAVID B. BURR
Osteoporosis
317
Osteogenesis
Imperfecta
325
Hyperparathyroidism
327
Hypoparathyroidism
329
Nutritional Rickets
/Osteomalacia
331
Hypophosphatemia
333
Hyperphosphatemia
336
Hypophosphatasia
337
Paget Disease of Bone
339
Osteopetroses
341
Suggested Readings
344
Pharmaceutical Treatments of Osteoporosis
345
BRUCE
H.
MITLAK, DAVID B. BURR AND MATTHEW R. ALLEN
Calcium and Vitamin
D
345
Anticatabolic Therapies
346
Anabolic Therapy
354
Combination Treatments
356
Emerging Therapies
359
Treatment Decisions
361
Suggested Readings
362
Index
365
|
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author_GND | (DE-588)1044624639 |
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ctrlnum | (OCoLC)864562961 (DE-599)BSZ393944840 |
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dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 612 - Human physiology |
dewey-raw | 612.751 |
dewey-search | 612.751 |
dewey-sort | 3612.751 |
dewey-tens | 610 - Medicine and health |
discipline | Biologie Medizin |
format | Book |
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illustrated | Illustrated |
indexdate | 2024-07-10T00:55:07Z |
institution | BVB |
isbn | 9780124160156 0124160158 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-026816879 |
oclc_num | 864562961 |
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owner_facet | DE-19 DE-BY-UBM DE-355 DE-BY-UBR |
physical | XV, 373 S. Ill., graph. Darst. 28 cm |
publishDate | 2014 |
publishDateSearch | 2014 |
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spelling | Basic and applied bone biology ed. by David B. Burr; Matthew R. Allen Amsterdam [u.a.] Elsevier 2014 XV, 373 S. Ill., graph. Darst. 28 cm txt rdacontent n rdamedia nc rdacarrier Bone Knochenstoffwechsel (DE-588)4216200-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Knochenstoffwechsel (DE-588)4216200-2 s DE-604 Burr, David B. Sonstige (DE-588)1044624639 oth Allen, M. R. Sonstige oth Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026816879&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Basic and applied bone biology Bone Knochenstoffwechsel (DE-588)4216200-2 gnd |
subject_GND | (DE-588)4216200-2 (DE-588)4143413-4 |
title | Basic and applied bone biology |
title_auth | Basic and applied bone biology |
title_exact_search | Basic and applied bone biology |
title_full | Basic and applied bone biology ed. by David B. Burr; Matthew R. Allen |
title_fullStr | Basic and applied bone biology ed. by David B. Burr; Matthew R. Allen |
title_full_unstemmed | Basic and applied bone biology ed. by David B. Burr; Matthew R. Allen |
title_short | Basic and applied bone biology |
title_sort | basic and applied bone biology |
topic | Bone Knochenstoffwechsel (DE-588)4216200-2 gnd |
topic_facet | Bone Knochenstoffwechsel Aufsatzsammlung |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026816879&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT burrdavidb basicandappliedbonebiology AT allenmr basicandappliedbonebiology |