ZEB1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression:
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| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 89 S. Ill., graph. Darst. 30 cm |
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Datensatz im Suchindex
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TABLE OF CONTENTS
TABLE OF CONTENTS
TABLE OF CONTENTS 1
I SUMMARY 3
II PUBLICATION LIST 5
III INTRODUCTION 6
1 MODES OF CELL MIGRATION 6
1.1 MULTICELLULAR MIGRATION 6
1.1.1 COLLECTIVE CELL MIGRATION 6
1.1.2 CELL INTERCALATION 7
1.2 EMT-MEDIATED SINGLE CELL MIGRATION 7
1.3 GASTRULATION MOVEMENTS 9
1.4 CELLULAR AND MOLECULAR MECHANISMS UNDERLYING GASTRULATION MOVEMENTS
11
1.4.1 EPIBOLY 11
1.4.2 INTERNALIZATION AND MIGRATION OF THE PRECHORDAL PLATE 13
1.4.3 CONVERGENCE AND EXTENSION 14
1.5 CELL MIGRATION DURING CANCER PROGRESSION 16
1.6 MIGRATING CANCER STEM CELLS 17
2 ZEB1 18
2.1 ROLES OF ZEB1 IN CANCER PROGRESSION 18
2.2 THE ZEBL/MICRORNA-200 FEEDBACK LOOP 20
2.3 ROLES OF ZEB1 DURING DEVELOPMENT 20
3 EPITHELIAL CELL ADHESION MOLECULES DYNAMICALLY REGULATED DURING EMT 21
3.1 E-CADHERIN 22
3.1.1 CHARACTERISTICS AND REGULATION OF E-CADHERIN-MEDIATED CELL-CELL
ADHESION 22
3.1.2 DYNAMIC ROLES OF E-CADHERIN DURING EARLY ZEBRAFISH DEVELOPMENT 22
3.2 THE EPITHELIAL CELL ADHESION MOLECULE (EPCAM) 23
3.2.1 CHARACTERISTICS OF EPCAM AND EPCAM SIGNALING 23
3.2.2 ROLES OF EPCAM IN CARCINOGENESIS 24
HTTP://D-NB.INFO/1042173524
IMAGE 2
2
TABLE OF CONTENTS
4 OBJECTIVES OF THIS THESIS 26
IV ORIGINAL PUBLICATIONS 27
CHAPTER 1 27
CHAPTER II 56
V REFERENCES 75
VI APPENDIX 87
ABBREVIATIONS 87
ACKNOWLEDGEMENTS 89
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| spelling | Vannier, Corinne 1980- Verfasser (DE-588)1042173362 aut ZEB1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression vorgelegt von Corinne Vannier 2013 89 S. Ill., graph. Darst. 30 cm txt rdacontent n rdamedia nc rdacarrier Freiburg (Breisgau), Univ., Diss., 2013 (DE-588)4113937-9 Hochschulschrift gnd-content DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026735936&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Vannier, Corinne 1980- ZEB1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression |
| subject_GND | (DE-588)4113937-9 |
| title | ZEB1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression |
| title_auth | ZEB1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression |
| title_exact_search | ZEB1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression |
| title_full | ZEB1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression vorgelegt von Corinne Vannier |
| title_fullStr | ZEB1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression vorgelegt von Corinne Vannier |
| title_full_unstemmed | ZEB1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression vorgelegt von Corinne Vannier |
| title_short | ZEB1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression |
| title_sort | zeb1 regulates cell migration and cell behavior during zebrafish gastrulation and cancer progression |
| topic_facet | Hochschulschrift |
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