Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
2012
|
| Schlagworte: | |
| Online-Zugang: | kostenfrei https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-253709 Inhaltsverzeichnis |
| Beschreibung: | 140 S. Ill., graph. Darst. |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV041130635 | ||
| 003 | DE-604 | ||
| 005 | 20130823 | ||
| 007 | t | ||
| 008 | 130708s2012 ad|| m||| 00||| eng d | ||
| 035 | |a (OCoLC)856815100 | ||
| 035 | |a (DE-599)BVBBV041130635 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-384 |a DE-473 |a DE-703 |a DE-1051 |a DE-824 |a DE-29 |a DE-12 |a DE-91 |a DE-19 |a DE-1049 |a DE-92 |a DE-739 |a DE-898 |a DE-355 |a DE-706 |a DE-20 |a DE-1102 | ||
| 082 | 0 | |a 540 | |
| 082 | 0 | |a 610 | |
| 084 | |a VK 5075 |0 (DE-625)147396: |2 rvk | ||
| 100 | 1 | |a Ruß, Carolin |d 1983- |e Verfasser |0 (DE-588)1036838943 |4 aut | |
| 245 | 1 | 0 | |a Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma |c vorgelegt von Carolin Ruß |
| 264 | 1 | |c 2012 | |
| 300 | |a 140 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 502 | |a Regensburg, Univ., Diss., 2012 | ||
| 650 | 0 | 7 | |a Enzyminhibitor |0 (DE-588)4152479-2 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Melanom |0 (DE-588)4074707-4 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Protein MIA |0 (DE-588)4642903-7 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4113937-9 |a Hochschulschrift |2 gnd-content | |
| 689 | 0 | 0 | |a Protein MIA |0 (DE-588)4642903-7 |D s |
| 689 | 0 | 1 | |a Enzyminhibitor |0 (DE-588)4152479-2 |D s |
| 689 | 0 | 2 | |a Melanom |0 (DE-588)4074707-4 |D s |
| 689 | 0 | |5 DE-604 | |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe |o urn:nbn:de:bvb:355-epub-253709 |
| 856 | 4 | 1 | |u http://epub.uni-regensburg.de/25370/ |x Verlag |z kostenfrei |3 Volltext |
| 856 | 4 | |u https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-253709 |x Resolving-System | |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026106467&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 912 | |a ebook | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-026106467 | ||
Datensatz im Suchindex
| _version_ | 1804150523981463552 |
|---|---|
| adam_text | IMAGE 1
CONTENTS
I. CONVERSION OF CARBOHYDRATES IN LOW MELTING MIXTURES 1
1. LOW MELTING MIXTURES - THE GREENER IONIC LIQUIDS?.
.......................................... 3
INTRODUCTION 4
CLASSIFICATION OF LOW MELTING MIXTURES AND THEIR SYNTHESIS 4
A) OVERVIEW OF THE PHYSICOCHEMICAL PROPERTIES 6
B) REACTIONS IN LOW MELTING MIXTURES 18
CONCLUSION AND OUTLOOK 24
2. EFFICIENT PREPARATION OF P-D-GLUCOSYL AND P-D-MANNOSYL UREAS AND
OTHER
N-GLUCOSIDES IN CARBOHYDRATE MELTS............. ............
...................... ........ 25
INTRODUCTION 26
RESULTS AND DISCUSSION 27
CONCLUSION 34
EXPERIMENTAL 35
3. SOLVENT-FREE PREPARATION OF 5-(A-D-GLUCOSYLOXYMETHYL) FURFURAL FROM
ISOMALTULOSE- CHOLINE CHLORIDE MELTS AND SYNTHESIS OF
AMWAFI/W^ -HEPTA-OACETYL-L-ISOMALTULOSYL)UREA............ .............
................ .................. ........... 41
INTRODUCTION 42
RESULTS AND DISCUSSION 43
CONCLUSION 45
EXPERIMENTAL 46
4. CONDENSATION AND DEHYDRATION REACTIONS OF L-SORBOSE IN ECO-FRIENDLY
MELT
SYSTEMS........... ............... ............. ...............
............... .................. 51
INTRODUCTION 52
RESULTS AND DISCUSSION 52
CONCLUSION 54
EXPERIMENTAL 55
HTTP://D-NB.INFO/1037993195
IMAGE 2
5. BASE-, METAL-, AND PHOTO CATALYSIS IN CARBOHYDRATE MELTS .......
......... 58
6. SUFIE CHEMIE ZUM DAHINSCHMELZEN - KOHLENHYDIAT-BASIERTE MEDIEN ALS
ALTERNATIVE LSSUNGSMITTEL UND ZUR UMSETZUNG VON ZUCKERN .......... 59
EINLEITUNG 60
PHYSIKALISCH-CHEMISCHE EIGENSCHAFTEN DER ZUCKERSCHMELZEN 60
KONVERSION VON KOHLENHYDRATEN IN DER SCHMELZE 62
ZUSAMMENFASSUNG 64
7. CONCLUSION ................... .............. ................
........... 65
8. ZUSAMMENFASSUNG.............. - 6 6
II. MELANOMA INHIBITORY ACTIVITY (MIA) PROTEIN INHIBITORS FOR
THE TREATMENT OF MALIGNANT MELANOMA 67
INTRODUCTION AND GOALS 67
9. MELANOMA INHIBITORY ACTIVITY (MIA) PROTEIN INHIBITORS - SYNTHESIS AND
BIOLOGICAL TESTING........ .............- ........ .......... 71
INTRODUCTION 72
RESULTS AND DISCUSSION 72
9.1 N-METHYLATION OF PEPTIDE BACKBONE - ...... ....... 72
92 PEPTOIDS (N-ALKYLATED GLYCINES)....... 73
93 CYCLISATION ..... 74
9.4 A FAST SCREENING PROCESS WAS APPLIED TO FIND POTENTIAL DRAG
CANDIDATES 78
CONCLUSION 84
EXPERIMENTAL 85
10. EVALUATION OF DIFFERENT DEVICES FOR THE DELIVERY OF MELANOMA
INHIBITORY ACTIVITY
(MIA) PROTEIN
INHIBITORS..............................................................-......................-..93
INTRODUCTION 94
10.1 CONJUGATION OF POLYETHYLENE GLYCOL) TO MELANOMA INHIBITORY ACTIVITY
(MIA)
INHIBITORS AND BIOLOGICAL EVALUATION ......... ...... ............95
INTRODUCTION. 95
RESULTS AND DISCUSSION 96
IMAGE 3
CONCLUSION 100
EXPERIMENTAL 100
10J LIPID IMPLANTS AS POTENTIAL CONTROLLED RELEASE SYSTEM FOR MELANOMA
INHIBITORY
ACTIVITY (MIA) PROTEIN INHIBITORS....... ...... 101
INTRODUCTION 101
RESULTS AND DISCUSSION 102
CONCLUSION 104
EXPERIMENTAL 105
10.3 POLYETHYLENE GLYCOL) BASED HYDROGELS FOR SUSTAINED DELIVERY OF
MELANOMA
INHIBITORY ACTIVITY (MIA) PROTEIN INHIBITORS- ............. 107
INTRODUCTION 107
RESULTS AND DISCUSSION 108
CONCLUSION I L L
EXPERIMENTAL 112
11. S U M M A R Y . . . . . . . . . . . . . . . . . . . . . . . . . 113
12. ZUSAMMENFASSUNG. ............ ............. 115
13.
BIBLIOGRAPHY....................................................................................................................
117
III. APPENDIX 131
14. ABBREVIATIONS...................... 132
15. LIST OF PUBLICATIONS........ ..........................
.................-136
16. CURRICULUM VITAE....................
...........................................
................................ 137
17. DANKSAGUNG .......................... ...................-138
|
| any_adam_object | 1 |
| author | Ruß, Carolin 1983- |
| author_GND | (DE-588)1036838943 |
| author_facet | Ruß, Carolin 1983- |
| author_role | aut |
| author_sort | Ruß, Carolin 1983- |
| author_variant | c r cr |
| building | Verbundindex |
| bvnumber | BV041130635 |
| classification_rvk | VK 5075 |
| collection | ebook |
| ctrlnum | (OCoLC)856815100 (DE-599)BVBBV041130635 |
| dewey-full | 540 610 |
| dewey-hundreds | 500 - Natural sciences and mathematics 600 - Technology (Applied sciences) |
| dewey-ones | 540 - Chemistry and allied sciences 610 - Medicine and health |
| dewey-raw | 540 610 |
| dewey-search | 540 610 |
| dewey-sort | 3540 |
| dewey-tens | 540 - Chemistry and allied sciences 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
| format | Thesis Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01995nam a2200445 c 4500</leader><controlfield tag="001">BV041130635</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20130823 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">130708s2012 ad|| m||| 00||| eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)856815100</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV041130635</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-384</subfield><subfield code="a">DE-473</subfield><subfield code="a">DE-703</subfield><subfield code="a">DE-1051</subfield><subfield code="a">DE-824</subfield><subfield code="a">DE-29</subfield><subfield code="a">DE-12</subfield><subfield code="a">DE-91</subfield><subfield code="a">DE-19</subfield><subfield code="a">DE-1049</subfield><subfield code="a">DE-92</subfield><subfield code="a">DE-739</subfield><subfield code="a">DE-898</subfield><subfield code="a">DE-355</subfield><subfield code="a">DE-706</subfield><subfield code="a">DE-20</subfield><subfield code="a">DE-1102</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">540</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">610</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VK 5075</subfield><subfield code="0">(DE-625)147396:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Ruß, Carolin</subfield><subfield code="d">1983-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)1036838943</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma</subfield><subfield code="c">vorgelegt von Carolin Ruß</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2012</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">140 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="502" ind1=" " ind2=" "><subfield code="a">Regensburg, Univ., Diss., 2012</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Enzyminhibitor</subfield><subfield code="0">(DE-588)4152479-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Melanom</subfield><subfield code="0">(DE-588)4074707-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Protein MIA</subfield><subfield code="0">(DE-588)4642903-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4113937-9</subfield><subfield code="a">Hochschulschrift</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Protein MIA</subfield><subfield code="0">(DE-588)4642903-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Enzyminhibitor</subfield><subfield code="0">(DE-588)4152479-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Melanom</subfield><subfield code="0">(DE-588)4074707-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Online-Ausgabe</subfield><subfield code="o">urn:nbn:de:bvb:355-epub-253709</subfield></datafield><datafield tag="856" ind1="4" ind2="1"><subfield code="u">http://epub.uni-regensburg.de/25370/</subfield><subfield code="x">Verlag</subfield><subfield code="z">kostenfrei</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="856" ind1="4" ind2=" "><subfield code="u">https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-253709</subfield><subfield code="x">Resolving-System</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">DNB Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026106467&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ebook</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-026106467</subfield></datafield></record></collection> |
| genre | (DE-588)4113937-9 Hochschulschrift gnd-content |
| genre_facet | Hochschulschrift |
| id | DE-604.BV041130635 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T00:40:17Z |
| institution | BVB |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-026106467 |
| oclc_num | 856815100 |
| open_access_boolean | 1 |
| owner | DE-384 DE-473 DE-BY-UBG DE-703 DE-1051 DE-824 DE-29 DE-12 DE-91 DE-BY-TUM DE-19 DE-BY-UBM DE-1049 DE-92 DE-739 DE-898 DE-BY-UBR DE-355 DE-BY-UBR DE-706 DE-20 DE-1102 |
| owner_facet | DE-384 DE-473 DE-BY-UBG DE-703 DE-1051 DE-824 DE-29 DE-12 DE-91 DE-BY-TUM DE-19 DE-BY-UBM DE-1049 DE-92 DE-739 DE-898 DE-BY-UBR DE-355 DE-BY-UBR DE-706 DE-20 DE-1102 |
| physical | 140 S. Ill., graph. Darst. |
| psigel | ebook |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| record_format | marc |
| spelling | Ruß, Carolin 1983- Verfasser (DE-588)1036838943 aut Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma vorgelegt von Carolin Ruß 2012 140 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Regensburg, Univ., Diss., 2012 Enzyminhibitor (DE-588)4152479-2 gnd rswk-swf Melanom (DE-588)4074707-4 gnd rswk-swf Protein MIA (DE-588)4642903-7 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Protein MIA (DE-588)4642903-7 s Enzyminhibitor (DE-588)4152479-2 s Melanom (DE-588)4074707-4 s DE-604 Erscheint auch als Online-Ausgabe urn:nbn:de:bvb:355-epub-253709 http://epub.uni-regensburg.de/25370/ Verlag kostenfrei Volltext https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-253709 Resolving-System DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026106467&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Ruß, Carolin 1983- Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma Enzyminhibitor (DE-588)4152479-2 gnd Melanom (DE-588)4074707-4 gnd Protein MIA (DE-588)4642903-7 gnd |
| subject_GND | (DE-588)4152479-2 (DE-588)4074707-4 (DE-588)4642903-7 (DE-588)4113937-9 |
| title | Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma |
| title_auth | Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma |
| title_exact_search | Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma |
| title_full | Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma vorgelegt von Carolin Ruß |
| title_fullStr | Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma vorgelegt von Carolin Ruß |
| title_full_unstemmed | Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma vorgelegt von Carolin Ruß |
| title_short | Conversion of carbohydrates in low melting mixtures and Melanoma Inhibitory Activity (MIA) protein inhibitors for the treatment of malignant melanoma |
| title_sort | conversion of carbohydrates in low melting mixtures and melanoma inhibitory activity mia protein inhibitors for the treatment of malignant melanoma |
| topic | Enzyminhibitor (DE-588)4152479-2 gnd Melanom (DE-588)4074707-4 gnd Protein MIA (DE-588)4642903-7 gnd |
| topic_facet | Enzyminhibitor Melanom Protein MIA Hochschulschrift |
| url | http://epub.uni-regensburg.de/25370/ https://nbn-resolving.org/urn:nbn:de:bvb:355-epub-253709 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026106467&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT rußcarolin conversionofcarbohydratesinlowmeltingmixturesandmelanomainhibitoryactivitymiaproteininhibitorsforthetreatmentofmalignantmelanoma |