Protein-nanoparticle interactions: the bio-nano interface
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Berlin [u.a.]
Springer
2013
|
| Schriftenreihe: | Springer Series in Biophysics
15 |
| Schlagworte: | |
| Online-Zugang: | Inhaltstext Inhaltsverzeichnis |
| Beschreibung: | X, 84 S. Ill., graph. Darst. 235 mm x 155 mm |
| ISBN: | 9783642375545 |
Internformat
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Datensatz im Suchindex
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| adam_text |
CONTENTS
1 THE BIOLOGICAL SIGNIFICANCE OF "NANO"-INTERACTIONS 1
1.1 NANOSCIENCE IN MEDICINE 1
1.2 NANOTECHNOLOGY AND MEDICAL APPLICATIONS 3
1.2.1 IMPLANTABLE BIOSENSORS 3
1.2.2 NANOSURGERY 4
1.2.3 TISSUE ENGINEERING 5
1.2.4 NANOPARTICLE-ENABLED DIAGNOSTICS 6
1.2.5 TARGETED DRUG DELIVERY 7
1.3 BRIDGING NANOSCIENCE AND NANOMEDICINE 7
1.4 THE NANOPARTICLE INTERFACE 8
1.4.1 INTERACTION OF NANOPARTICLES WITH ENVIRONMENTAL
BIOMOLECULES 8
1.4.2 BIOLOGICAL RESPONSE TO NANOMATERIALS 13
1.5 CYTOTOXICITY 14
1.6 CONCLUSION 16
REFERENCES 17
2 NANOPARTICLE AND PROTEIN CORONA 21
2.1 STRUCTURE AND COMPOSITION OF CORONA 22
2.1.1 HARD CORONA 23
2.1.2 SOFT CORONA 25
2.2 PROTEIN CONFORMATION 25
2.3 DYNAMIC OF PROTEIN CORONA AND ITS TIME EVOLUTION 26
2.3.1 EARLY STAGE 27
2.3.2 LATE STAGE 27
2.4 PARAMETERS AFFECTING PROTEIN CORONA 29
2.4.1 SURFACE CHARGE OF NANOPARTICLE 30
2.4.2 NANOPARTICLE MATERIAL 30
2.4.3 SURFACE FUNCTIONALIZATION AND COATINGS 30
HTTP://D-NB.INFO/1032088192
X CONTENTS
2.4.4 HYDROPHILICITY/HYDROPHOBICITY 31
2.4.5 NANOPARTICLE SIZE 32
2.4.6 BIOLOGICAL ENVIRONMENT 33
2.5 IGNORED ISSUES OF PROTEIN CORONA 35
2.5.1 TEMPERATURE 35
2.5.2 GRADIENT PLASMA 39
2.6 CONCLUSION 42
REFERENCES 42
3 PROTEIN CORONA: APPLICATIONS AND CHALLENGES 45
3.1 WHAT CELLS SEE OF NANOPARTICLES 46
3.2 NPS CIRCULATION INSIDE THE BODY 49
3.3 TARGETING 53
3.4 TOXICITY 55
3.5 PROTEIN DENATURE OR FIBRILLATION 56
3.6 PROBLEMS OF PROTEIN CORONA 57
3.7 CONCLUSION 60
REFERENCES 61
4 ANALYTICAL METHODS FOR CORONA EVALUATIONS 65
4.1 CENTRIFUGATION 68
4.2 CIRCULAR DICHROISM 69
4.3 ISOTHERMAL TITRATION CALORIMETRY 70
4.4 SDS-PAGE 72
4.4.1 CAPILLARY ELECTROPHORESIS 72
4.4.2 ONE-DIMENSIONAL GEL ELECTROPHORESIS 72
4.4.3 TWO-DIMENSIONAL GEL ELECTROPHORESIS 72
4.5 UV-VISIBLE SPECTROSCOPY 75
4.6 FLUORESCENCE SPECTROSCOPY 76
4.7 MASS SPECTROMETRY 77
4.8 FOURIER TRANSFORM INFRARED AND RAMAN SPECTROSCOPIES 78
4.9 NMR 79
4.10 X-RAY 79
4.11 DIFFERENTIAL CENTRIFUGATION SEDIMENTATION 79
REFERENCES 80
INDEX 83 |
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV041110599 |
| classification_rvk | VE 9850 WD 2200 WD 5100 |
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| dewey-ones | 547 - Organic chemistry |
| dewey-raw | 547.7 |
| dewey-search | 547.7 |
| dewey-sort | 3547.7 |
| dewey-tens | 540 - Chemistry and allied sciences |
| discipline | Chemie / Pharmazie Biologie |
| format | Book |
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| indexdate | 2024-09-10T00:58:44Z |
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| isbn | 9783642375545 |
| language | English |
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| physical | X, 84 S. Ill., graph. Darst. 235 mm x 155 mm |
| publishDate | 2013 |
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| series | Springer Series in Biophysics |
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| spelling | Protein-nanoparticle interactions the bio-nano interface Masoud Rahman ... Berlin [u.a.] Springer 2013 X, 84 S. Ill., graph. Darst. 235 mm x 155 mm txt rdacontent n rdamedia nc rdacarrier Springer Series in Biophysics 15 Biologische Aktivität (DE-588)4291566-1 gnd rswk-swf Proteine (DE-588)4076388-2 gnd rswk-swf Nanopartikel (DE-588)4333369-2 gnd rswk-swf Wechselwirkung (DE-588)4064937-4 gnd rswk-swf Adsorbat (DE-588)4141453-6 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Nanopartikel (DE-588)4333369-2 s Proteine (DE-588)4076388-2 s Adsorbat (DE-588)4141453-6 s DE-604 Biologische Aktivität (DE-588)4291566-1 s Wechselwirkung (DE-588)4064937-4 s b DE-604 Rahman, Masoud Sonstige oth Erscheint auch als Online-Ausgabe 978-3-642-37555-2 Springer Series in Biophysics 15 (DE-604)BV000666176 15 X:MVB text/html http://deposit.dnb.de/cgi-bin/dokserv?id=4275468&prov=M&dok_var=1&dok_ext=htm Inhaltstext DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=026086804&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Protein-nanoparticle interactions the bio-nano interface Springer Series in Biophysics Biologische Aktivität (DE-588)4291566-1 gnd Proteine (DE-588)4076388-2 gnd Nanopartikel (DE-588)4333369-2 gnd Wechselwirkung (DE-588)4064937-4 gnd Adsorbat (DE-588)4141453-6 gnd |
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| title | Protein-nanoparticle interactions the bio-nano interface |
| title_auth | Protein-nanoparticle interactions the bio-nano interface |
| title_exact_search | Protein-nanoparticle interactions the bio-nano interface |
| title_full | Protein-nanoparticle interactions the bio-nano interface Masoud Rahman ... |
| title_fullStr | Protein-nanoparticle interactions the bio-nano interface Masoud Rahman ... |
| title_full_unstemmed | Protein-nanoparticle interactions the bio-nano interface Masoud Rahman ... |
| title_short | Protein-nanoparticle interactions |
| title_sort | protein nanoparticle interactions the bio nano interface |
| title_sub | the bio-nano interface |
| topic | Biologische Aktivität (DE-588)4291566-1 gnd Proteine (DE-588)4076388-2 gnd Nanopartikel (DE-588)4333369-2 gnd Wechselwirkung (DE-588)4064937-4 gnd Adsorbat (DE-588)4141453-6 gnd |
| topic_facet | Biologische Aktivität Proteine Nanopartikel Wechselwirkung Adsorbat Aufsatzsammlung |
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