Biomedical applications of control engineering:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Berlin [u.a.]
Springer
2013
|
| Schriftenreihe: | Lecture notes in control and information sciences
441 |
| Schlagworte: | |
| Online-Zugang: | Inhaltstext Inhaltsverzeichnis |
| Beschreibung: | XIV, 274 S. graph. Darst. |
| ISBN: | 9783642372780 3642372783 |
Internformat
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| 245 | 1 | 0 | |a Biomedical applications of control engineering |c Selim S. Hacısalihzade |
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Datensatz im Suchindex
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CONTENTS
1 INTRODUCTION TO SYSTEMS 1
1.1 INTRODUCTION 1
1.2 SOME SPECIAL TYPES OF SYSTEMS 3
1.3 MATHEMATICAL DESCRIPTION AND ANALYSIS OF SYSTEMS 4
1.3.1 INPUT-OUTPUT DESCRIPTION OF SYSTEMS IN TIME DOMAIN . 4
1.3.2 INPUT-OUTPUT DESCRIPTION OF SYSTEMS IN FREQUENCY
DOMAIN 7
1.3.3 STATE SPACE DESCRIPTION OF SYSTEMS 8
1.4 SOME IMPORTANT SYSTEM PROPERTIES 14
1.5 STABILITY 15
1.5.1 BIBO STABILITY 15
1.5.2 LYAPUNOV STABILITY 17
1.6 EXERCISES 19
2 MODELING AND IDENTIFICATION 23
2.1 INTRODUCTION 23
2.2 WHAT IS A MODEL? 24
2.3 MODELING PROCESS 31
2.3.1 INVERTED PENDULUM 31
2.3.2 STOCK PRICES 33
2.3.3 LESSONS LEARNED 36
2.4 PARAMETER IDENTIFICATION 37
2.5 MODEL VALIDATION 38
2.6 SUMMARY 39
2.7 EXERCISES 41
3 THE HUMAN OPERATOR 45
3.1 INTRODUCTION 45
3.2 TYPES OF MANUAL CONTROL SYSTEMS 51
3.3 HUMAN OPERATOR MODELS 53
3.3.1 SECOND ORDER LINEAR MODEL 53
3.3.2 DESCRIBING FUNCTION MODEL 54
HTTP://D-NB.INFO/103159549X
XII
CONTENTS
3.3.3 OPTIMAL CONTROL MODEL 54
3.4 EXERCISES 58
4 DRUG ADMINISTRATION AND DOSAGE OPTIMIZATION 61
4.1 INTRODUCTION 61
4.2 OPTIMIZATION OF DRUG DELIVERY BASED ON PHARMACOKINETIC DATA. 64
4.2.1 MODELING PHARMACOKINETIC RELATIONSHIPS 65
4.2.2 THE MULTIPLE DOSING PROBLEM 66
4.2.3 LINEAR PROGRAMMING SOLUTIONS OF THE MULTIPLE DOSING
PROBLEM 68
4.2.4 SOLUTION OF THE MULTIPLE DOSING PROBLEM WITH A
QUADRATIC OBJECTIVE FUNCTION 83
4.2.5 SEMI-ANALYTICAL SOLUTION OF THE MULTIPLE DOSING
PROBLEM 86
4.2.6 OPTIMIZATION OF DRUG ADMINISTRATION BY A TAUBERIAN
APPROACH 88
4.2.7 REMARKS ON PHARMACOKINETIC OPTIMIZATION 92
4.3 OPTIMIZATION OF DRUG DELIVERY BASED ON PHARMACODYNAMIC
DATA 95
4.4 EXERCISES 97
5 PARKINSON'S DISEASE 99
5.1 INTRODUCTION 99
5.2 ETIOLOGY 99
5.3 PATHOPHYSIOLOGY 101
5.4 SYMPTOMS 103
5.5 TREATMENT 104
5.6 MEASURING PARKINSONIAN SYMPTOMS 106
5.6.1 MEASURING TREMOR 109
5.6.2 MEASURING BRADYKINESIA 112
5.6.3 LOW-TECH APPROACH 115
5.7 DOSAGE OPTIMIZATION IN PARKINSON'S DISEASE 116
5.7.1 PARKINSON PATIENTS ARE POOR CONTROLLERS 117
5.7.2 MODELING THE EFFECTS OF LEVODOPA ON PARKINSON
SYMPTOMS 121
5.8 OPTIMAL CONTROL OF LEVODOPA THERAPY 127
5.9 A CASE STUDY 130
5.10 SUMMARY 133
5.11 EXERCISES 134
6 DIABETES AND CONTROL OF BLOOD GLUCOSE 137
6.1 INTRODUCTION 137
6.2 MEASURING BLOOD GLUCOSE LEVELS 141
6.2.1 INVASIVE
TECHNIQUES 141
6.2.2 MINIMALLY-INVASIVE TECHNIQUES 142
CONTENTS XIII
6.2.3 NON-INVASIVE
TECHNIQUES 145
6.2.4 CLARKE'S ERROR GRID ANALYSIS 146
6.3 INSULIN DELIVERY 148
6.4 PATIENT DYNAMICS 149
6.4.1 MATHEMATICAL MODELS 152
6.5 THE
CONTROLLER 159
6.5.1 RULE BASED CONTROL 159
6.5.2 MODEL BASED CONTROL ALGORITHMS 161
6.6 COMMERCIAL INSULIN PUMPS 164
6.6.1 ACCU-
CHEK 165
6.7 EXERCISES 172
7 CONTROLLING DEPTH OF ANAESTHESIA 175
7.1 INTRODUCTION 175
7.2 MEASURING DEPTH OF ANAESTHESIA 175
7.3 ANAESTHETIC AGENTS 176
7.4 THE BASIC CONTROL LOOP 177
7.5 FUZZY CONTROL OF ANAESTHESIA 178
7.6 MULTIVARIATE CONTROL OF ANAESTHESIA 182
7.7 IMPLEMENTATION OF THE MULTIVARIATE CONTROLLER 184
7.8 THE PATIENT MODEL 185
7.9 THE BREATHING SYSTEM 194
7.10 SURGICAL STIMULATION 204
7.11 MODEL INTEGRATION 210
7.12 CONTROLLER DESIGN AND IMPLEMENTATION 213
7.12.1 OBSERVER BASED STATE FEEDBACK CONTROLLER
WITH REFERENCE TRACKING 213
7.12.2 ARTIFACT HANDLING 215
7.12.3 IMPLEMENTATION 216
7.13 EXERCISES 218
APPENDIX A OPTIMAL CONTROL 219
A.I INTRODUCTION 219
A.2 CALCULUS OF VARIATIONS 220
A.2.1 SUBJECT MATTER 220
A.2.2 FIXED ENDPOINT PROBLEM 221
A.2.3 VARIABLE ENDPOINT PROBLEM 222
A.2.4 VARIATION PROBLEM WITH CONSTRAINTS 224
A.3 OPTIMAL DYNAMIC SYSTEMS 224
A.3.1 FIXED ENDPOINT PROBLEM 224
A.3.2 VARIABLE ENDPOINT PROBLEM 227
A.3.3 GENERALIZED OBJECTIVE FUNCTION 229
A.4 PONTRYAGIN'S MINIMUM PRINCIPLE 230
A.5 HAMILTON-JACOBI METHOD 233
A.6 OPTIMAL CONTROL OF LINEAR SYSTEMS 237
XIV
CONTENTS
A.6.1 RICCATI EQUATION 237
A.6.2 OPTIMAL CONTROL WHEN NOT ALL STATES ARE MEASURABLE . 241
A.6.3 DYNAMIC PROGRAMMING 243
APPENDIX B FUZZY LOGIC CONTROL 247
B.L FUZZY LOGIC ARCHITECTURE 247
B.L.L MEMBERSHIP FUNCTIONS 248
B.L.2 FUZZIFICATION 250
B.L.3 FUZZY RULE BASE 251
B.L.4 INFERENCE ENGINE 251
B.L.5 DEL'UZZIFICATION 252
B.2 FUZZY LOGIC TOOLBOX OF MATLAB 253
B.3 APPLICATION: FUZZY CONTROL OF A SYSTEM 254
REFERENCES 259 |
| any_adam_object | 1 |
| author | Hacısali̇hzade, Seli̇m S. |
| author_facet | Hacısali̇hzade, Seli̇m S. |
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| author_sort | Hacısali̇hzade, Seli̇m S. |
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| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.580115 |
| dewey-search | 615.580115 |
| dewey-sort | 3615.580115 |
| dewey-tens | 610 - Medicine and health |
| discipline | Mathematik Medizin |
| format | Book |
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| isbn | 9783642372780 3642372783 |
| language | English |
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| physical | XIV, 274 S. graph. Darst. |
| publishDate | 2013 |
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| series | Lecture notes in control and information sciences |
| series2 | Lecture notes in control and information sciences |
| spelling | Hacısali̇hzade, Seli̇m S. Verfasser aut Biomedical applications of control engineering Selim S. Hacısalihzade Berlin [u.a.] Springer 2013 XIV, 274 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Lecture notes in control and information sciences 441 Pharmakotherapie (DE-588)4076066-2 gnd rswk-swf Kontrolltheorie (DE-588)4032317-1 gnd rswk-swf Pharmakotherapie (DE-588)4076066-2 s Kontrolltheorie (DE-588)4032317-1 s DE-604 Lecture notes in control and information sciences 441 (DE-604)BV005848579 441 X:MVB text/html http://deposit.dnb.de/cgi-bin/dokserv?id=4258632&prov=M&dok_var=1&dok_ext=htm Inhaltstext DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025958778&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Hacısali̇hzade, Seli̇m S. Biomedical applications of control engineering Lecture notes in control and information sciences Pharmakotherapie (DE-588)4076066-2 gnd Kontrolltheorie (DE-588)4032317-1 gnd |
| subject_GND | (DE-588)4076066-2 (DE-588)4032317-1 |
| title | Biomedical applications of control engineering |
| title_auth | Biomedical applications of control engineering |
| title_exact_search | Biomedical applications of control engineering |
| title_full | Biomedical applications of control engineering Selim S. Hacısalihzade |
| title_fullStr | Biomedical applications of control engineering Selim S. Hacısalihzade |
| title_full_unstemmed | Biomedical applications of control engineering Selim S. Hacısalihzade |
| title_short | Biomedical applications of control engineering |
| title_sort | biomedical applications of control engineering |
| topic | Pharmakotherapie (DE-588)4076066-2 gnd Kontrolltheorie (DE-588)4032317-1 gnd |
| topic_facet | Pharmakotherapie Kontrolltheorie |
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