Verfügbarkeit: DNA helicases and DNA motor proteins

DNA helicases and DNA motor proteins:

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Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	New York, NY [u.a.] Springer 2013
Schriftenreihe:	Advances in experimental medicine and biology 767
Online-Zugang:	FAN01 UBT01 Volltext Inhaltsverzeichnis Abstract
Beschreibung:	1 Online-Ressource
ISBN:	9781461450375
DOI:	10.1007/978-1-4614-5037-5

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Datensatz im Suchindex

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adam_text	DNA HELICASES AND DNA MOTOR PROTEINS / : 2013 TABLE OF CONTENTS / INHALTSVERZEICHNIS PREFACE OVERVIEW: WHAT ARE DNA HELICASES? STRUCTURE AND MECHANISMS OF SF1 DNA HELICASES STRUCTURE AND MECHANISMS OF SF2 DNA HELICASES STRUCTURE AND MECHANISMS OF HEXAMERIC HELICASES HELICASES AT THE REPLICATION FORK DNA HELICASES ASSOCIATED WITH GENETIC INSTABILITY, CANCER AND AGING THE HELICASE-PRIMASE COMPLEX AS A TARGET FOR EFFECTIVE HERPESVIRUS ANTIVIRALS RECQ HELICASES - CONSERVED GUARDIANS OF GENETIC INTEGRITY ROLES OF DNA HELICASES IN THE MEDIATION AND RREGULATION OF HOMOLOGOUS RECOMBINATION DNA HELICASES IN NER, BER ANDMMR ROLES FOR HELICASES AS ATP-DEPENDENT MOLECULAR SWITCHES THE FTSK FAMILY OF DNA PUMPS ATP DEPENDENT CHROMATIN REMODELERS INDEX DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT. DNA HELICASES AND DNA MOTOR PROTEINS / : 2013 ABSTRACT / INHALTSTEXT IN RECENT YEARS, A NUMBER OF GROUNDBREAKING STRUCTURAL AND MECHANISTIC STUDIES DEEPENED OUR UNDERSTANDING OF HELICASE MECHANISMS AND ESTABLISHED NEW APPROACHES FOR THEIR ANALYSES. MANY FUNDAMENTAL MECHANISTIC QUESTIONS RANGING FROM THE MECHANISM OF FORCE GENERATION, MECHANOCHEMICAL COUPLING TO DISTINCT MECHANISMS BY WHICH THE SAME ENZYME TRANSLOCATES ON DNA REMOVING OBSTACLES, UNWINDS DNA AND/OR REMODELS NUCLEOPROTEIN COMPLEXES, HOWEVER, REMAIN TO BE ANSWERED. IT IS EVEN LESS UNDERSTOOD HOW THE HELICASE MOTORS ARE INCORPORATED INTO A WIDE RANGE OF GENOME MAINTENANCE AND REPAIR MACHINES. THE FIELD HAS REACHED A STAGE WHEN THE STUDIES OF MOLECULAR MECHANISMS AND BASIC BIOLOGY OF HELICASES CAN AND SHALL BE INTEGRATED WITH THE STUDIES OF DEVELOPMENT, CANCER AND LONGEVITY. THE OBJECTIVE OF THIS BOOK IS TO PROVIDE THE FIRST SYSTEMATIC OVERVIEW OF STRUCTURE, FUNCTION AND REGULATION OF DNA HELICASES AND RELATED MOLECULAR MOTORS. BY INTEGRATING THE KNOWLEDGE OBTAINED THROUGH THE DIVERSE TECHNICAL APPROACHES RANGING FROM SINGLE-MOLECULE BIOPHYSICS TO CELLULAR AND MOLECULAR BIOLOGICAL STUDIESTHE EDITORSAIM TO PROVIDE A UNIFIED VIEW ON HOW HELICASES FUNCTION IN THE CELL, ARE REGULATED IN RESPONSE TO DIFFERENT CELLULAR STRESSES AND ARE INTEGRATED INTO LARGE MACROMOLECULAR ASSEMBLIES TO FORM A COMPLEX AND ADAPTIVE LIVING SYSTEM DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
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spelling	DNA helicases and DNA motor proteins Maria Spies, ed. [Contributors: Suja Aarattuthodiyil ...] New York, NY [u.a.] Springer 2013 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Advances in experimental medicine and biology 767 Spies, Maria Sonstige (DE-588)1121613578 oth Aarattuthodiyil, Suja Sonstige oth Erscheint auch als Druckausgabe 978-1-4614-5036-8 Advances in experimental medicine and biology 767 (DE-604)BV023059251 767 https://doi.org/10.1007/978-1-4614-5037-5 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025729755&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025729755&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract
spellingShingle	DNA helicases and DNA motor proteins Advances in experimental medicine and biology
title	DNA helicases and DNA motor proteins
title_auth	DNA helicases and DNA motor proteins
title_exact_search	DNA helicases and DNA motor proteins
title_full	DNA helicases and DNA motor proteins Maria Spies, ed. [Contributors: Suja Aarattuthodiyil ...]
title_fullStr	DNA helicases and DNA motor proteins Maria Spies, ed. [Contributors: Suja Aarattuthodiyil ...]
title_full_unstemmed	DNA helicases and DNA motor proteins Maria Spies, ed. [Contributors: Suja Aarattuthodiyil ...]
title_short	DNA helicases and DNA motor proteins
title_sort	dna helicases and dna motor proteins
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