Role of the transcriptome in breast cancer prevention:
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer
2013
|
| Schlagworte: | |
| Online-Zugang: | FAN01 UBT01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9781461448839 9781461448846 |
| DOI: | 10.1007/978-1-4614-4884-6 |
Internformat
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Datensatz im Suchindex
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|---|---|
| adam_text | ROLE OF THE TRANSCRIPTOME IN BREAST CANCER PREVENTION
/ RUSSO, JOSE
: 2013
TABLE OF CONTENTS / INHALTSVERZEICHNIS
PREFACE
THE EPIDEMIOLOGY OF BREAST CANCER AND THE BASIS FOR PREVENTION
IN VIVO MODEL FOR BREAST CANCER PREVENTION
COMPARATIVE EFFECTS OF THE PREVENTIVE EFFECT OF PREGNANCY, STEROIDAL
HORMONES AND HCG IN THE TRANSCRIPTOMIC PROFILE OF THE RAT MAMMARY GLAND
THE USE OF IN VITRO THREE-DIMENSIONAL SYSTEM FOR TESTING PREVENTING
AGENTS
METHODOLOGICAL APPROACH FRO STUDYING THE HUMAN BREAST
THE TRANSCRIPTOMA OF BREAST CANCER PREVENTION
CHROMATIN REMODELING AND PREGNANCY INDUCED DIFFERENTIATION
THE ROLE OF SPLICEOSOME IN THE HUMAN BREAST
NON CODING RNAS AND BREAST CANCER PREVENTION
THE ROLE OF STEM CELL IN BREAST CANCER PREVENTION
INDEX
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
ROLE OF THE TRANSCRIPTOME IN BREAST CANCER PREVENTION
/ RUSSO, JOSE
: 2013
ABSTRACT / INHALTSTEXT
THIS BOOK IS DESIGNED FOR ADVANCED STUDENTS AND RESEARCHERS IN CELL
BIOLOGY, BIOCHEMISTRY, MOLECULAR BIOLOGY, MEDICINE IN GENERAL, AND
CANCER IN PARTICULAR. IT PROVIDES THE LATEST DATA ON THE TRANSCRIPTOME
OF THE MAMMARY GLAND IN ORDER TO ESTABLISH THE MOLECULAR AND CELLULAR
BIOLOGY OF DIFFERENTIATION LEADING TO CANCER PREVENTION. THE AUTHORS
HAVE BASED THEIR WORK ON THE EPIDEMIOLOGICAL EVIDENCE THAT EARLY FIRST
FULL TERM PREGNANCY IS A PROTECTIVE FACTOR IN HUMANS AGAINST BREAST
CANCER AND USING THIS KNOWLEDGE HAVE DEVELOPED IN VIVO AND IN VITRO
EXPERIMENTAL SYSTEMS THAT HAVE DEMONSTRATED MECHANISTICALLY HOW THE
DIFFERENTIATION TAKES PLACE. THE TRANSCRIPTOMA ANALYSIS OF THE FEMALE
BREAST SHOWS THAT AN EARLY FIRST FULL TERM PREGNANCY REPROGRAMS THE
ORGAN BY IMPRINTING A GENOMIC SIGNATURE THAT DIFFERS ACCORDING TO
REPRODUCTIVE HISTORY. THIS REPROGRAMMING TAKES PLACE AT THE CHROMATIN
LEVEL BY CHANGING THE TRANSCRIPTIONAL PROCESS. THE MODIFICATION OF THE
TRANSCRIPTIONAL CONTROL IS DUE TO THE EXPRESSION OF NON-CODING RNA
SEQUENCES AND POST-TRANSCRIPTIONAL CONTROL DRIVEN BY THE SPLICEOSOME.
THE PLASTICITY OF THE GENOME OF THE HUMAN BREAST MAKES POSSIBLE THIS
REPROGRAMMING THAT IS NOT ONLY INDUCED BY THE PHYSIOLOGICAL PROCESS OF
PREGNANCY BUT BY THE USE OF HORMONES MIMICKING PREGNANCY. THE ROLE OF
STEM CELLS AND THEIR REPROGRAMMING DURING DIFFERENTIATION ARE PRESENTED
AS A NEW PARADIGM IN BREAST CANCER PREVENTION
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
| any_adam_object | 1 |
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| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-4614-4884-6 |
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| spelling | Russo, Jose 1942- Verfasser (DE-588)1164725238 aut Role of the transcriptome in breast cancer prevention Jose Russo ; Irma H. Russo Boston, MA Springer 2013 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Medizin Medicine Oncology Toxicology Prävention (DE-588)4076308-0 gnd rswk-swf Brustkrebs (DE-588)4008528-4 gnd rswk-swf Brustkrebs (DE-588)4008528-4 s Prävention (DE-588)4076308-0 s 1\p DE-604 Russo, Irma H. Verfasser aut https://doi.org/10.1007/978-1-4614-4884-6 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025726726&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025726726&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Russo, Jose 1942- Russo, Irma H. Role of the transcriptome in breast cancer prevention Medizin Medicine Oncology Toxicology Prävention (DE-588)4076308-0 gnd Brustkrebs (DE-588)4008528-4 gnd |
| subject_GND | (DE-588)4076308-0 (DE-588)4008528-4 |
| title | Role of the transcriptome in breast cancer prevention |
| title_auth | Role of the transcriptome in breast cancer prevention |
| title_exact_search | Role of the transcriptome in breast cancer prevention |
| title_full | Role of the transcriptome in breast cancer prevention Jose Russo ; Irma H. Russo |
| title_fullStr | Role of the transcriptome in breast cancer prevention Jose Russo ; Irma H. Russo |
| title_full_unstemmed | Role of the transcriptome in breast cancer prevention Jose Russo ; Irma H. Russo |
| title_short | Role of the transcriptome in breast cancer prevention |
| title_sort | role of the transcriptome in breast cancer prevention |
| topic | Medizin Medicine Oncology Toxicology Prävention (DE-588)4076308-0 gnd Brustkrebs (DE-588)4008528-4 gnd |
| topic_facet | Medizin Medicine Oncology Toxicology Prävention Brustkrebs |
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