Verfügbarkeit: Neuropathology

Neuropathology: a reference text of CNS pathology

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Bibliographische Detailangaben
Format:	Buch
Sprache:	English
Veröffentlicht:	Edinburgh [u.a.] Mosby, Elsevier 2013
Ausgabe:	3. ed.
Schlagworte:	Neurologie Neuropathologie Zenuwstelsel Zenuwstelselaandoeningen Nervous System Diseases > pathology Nervous system > Diseases Nervous system > Diseases > Diagnosis Pathologie Zentralnervensystem Aufsatzsammlung Einführung
Online-Zugang:	Inhaltsverzeichnis Klappentext
Beschreibung:	XIII, 879 S. zahlr. Ill., graph. Darst.
ISBN:	0723435154 9780723435150

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Datensatz im Suchindex

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adam_text	Contents Acknowledgments Preface to First Edition Preface to Second Edition Preface to Third Edition Section 1: Pathologic reactions in the CNS Chapter 1 Pathologic reactions in the CNS Pathologic responses in neurons Normal neuronal cytology and staining Abnormalities of neuronal morphology Nuclear inclusions Neuronal cytoplasmic inclusions Cytoskeletal and filamentous inclusions Cytosolic inclusions Membrane-bound cytoplasmic inclusions Structural abnormalities of axons Axonal spheroids and dystrophic Pathologic reactions of astrocytes Pathologic reactions of oligodendroglia Immunohistochemical features Pathologic reactions of ependyma Immunohistochemical features Responses to injury Inclusions in ependymal cells and choroid plexus epithelium Pathologic reactions of microglia Microglial activation and rod cell formation Mineralization in the brain Pathologic reactions of blood vessels xiv xv Pediatrics xvi xvii Chapter 2 Fetal and neonatal hypoxic-ischemic lesions 33 Fetal lesions 33 Hydranencephaly 34 Basket brain 34 3 Porencephaly and schizencephaly 35 3 Multicystic encephalopathy 36 3 Perinatal lesions 37 3 Acute hemorrhage 37 7 Subdural hemorrhage (SDH) 37 8 Subarachnoid hemorrhage (SAH) 38 8 Subpiai hemorrhage (SPH) 38 8 Subependymal germinal plate/matrix hemorrhage (SEH) 38 9 Cerebral and cerebellar hemorrhage 39 11 Choroid plexus hemorrhage (CPH) 41 11 Acute white matter lesions 41 12 White matter necrosis (WMN) 41 16 Other patterns of white matter damage 44 16 Acute gray matter lesions 46 20 Cerebral necrosis 46 20 Pontosubicular necrosis 47 20 Basal ganglia and thalamic lesions 49 Cerebellar lesions 49 21 Brain stem lesions 49 22 Spinal cord lesions 49 22 Chronic lesions 49 24 Post-hemorrhagic lesions 49 25 Post-hemorrhagic hydrocephalus 50 vi Neuropathology Post-white matter necrosis Post-gray matter necrosis Status marmoratus Unilateral hypertrophy of the pyramidal tract Crossed cerebellar atrophy Kemicterus Chapter 3 Malformations Neural tube defects: dysraphic disorders Defects of neural tube closure Anencephaly Myelomeningocele Hemiation of neural tube through axial mesodermal defects Encephalocele Meningocele Occult spina bifida Chiari malformations Chiari type I malformation Chiari type II (Amold-Chiari) Malformation Chiari type III malformation Disorders of forebrain induction Holoprosencephaly Alobar holoprosencephaly Semilobar holoprosencephaly Lobar holoprosencephaly Olfactory aplasia Atelencephaly and aprosencephaly Agenesis of the corpus callosum Anomalies of the septum pellucidum Septo-optic dysplasia Cavum septi pellucidi and cavum vergae Malformations of cortical development Agyria and pachygyria Cerebro-ocular dysplasias Neu-laxova syndrome Polymicrogyria Chondrodysplasias Neuronal heterotopias within cerebral white matter Diffuse neuronal heterotopia Nodular heterotopia Laminar heterotopia Microdysgenesis 50 50 51 51 54 54 57 57 58 58 60 61 61 63 63 63 63 65 65 66 66 66 66 69 69 70 70 70 74 74 76 76 76 82 84 84 88 88 88 88 88 91 Cortical dysplasia with cytomegaly 91 Cortical dysplasia with hemimegalencephaly 91 Focal cortical dysplasia 96 Leptomeningeal glioneuronal heterotopia 96 Nodular cortical dysplasia 96 Status verrucosus simplex or status pseudoverrucosus 97 Hippocampal anomalies 97 Microcephaly 98 Chromosomal and single gene defects 99 Environmental factors 100 Megalencephaly 101 Malformations of the cerebellum 101 Cerebellar agenesis 103 Dandy-Walker syndrome 103 Joubert syndrome 105 Pontoneocerebellar hypoplasia (PNCH) 105 Cerebellar hypoplasia in other contexts 107 Granule cell aplasia 107 Cerebellar heterotopias 108 Cerebellar cortical dysplasia 108 Brain stem malformations 109 Olivary heterotopia 109 Olivary and dentate dysplasias 110 Möbius syndrome 111 Malformations of the spinal cord 113 Syringomyelia 113 Syringobulbia 113 Arthrogryposis multiplex congenita 114 Arachnoid cysts 114 Dysgenetic syndromes 114 Sturge-Weber syndrome 115 Tuberous sclerosis (Boumeville s disease) 116 Obstruction of the aqueduct of sylvius 119 Obstruction of the fourth ventricular exit foramina 121 Post-inflammatory or fibrotic obstruction of the CSF 123 Chapter 5 Disorders that primarily affect white matter 127 Pelizaeus-Merzbacher disease 127 Canavan s disease 129 Alexander s disease ізо Other leukodystrophies 132 CONTENTS VÌI Chapter 6 Neurodegenerative disorders of gray matter in childhood 139 Cerebral cortex 139 Alpers-Huttenlocher syndrome or progressive neuronal degeneration of childhood (PNDC) 139 Basal ganglia 142 Holotopistic striatal necrosis (familial striatal degeneration) 142 Neurodegeneration with brain iron accumulation- 1 (Hallervorden-Spatz disease) 142 Cerebellum 144 Menkes disease 144 Ataxia-telangiectasia 144 Carbohydrate-deficient glycoprotein syndrome type 1 (CDG 1) 144 Cerebellocortical degeneration (Jervis) Autosomal dominant cerebellar ataxia type II (ADCA II) Brain stem Hereditary motor neuropathy Infantile neuro-axonal dystrophy (INAD) Leigh s disease (subacute necrotizing encephalomyelopathy) Spinal cord Spinal muscular atrophy (SMA) Chapter/ Miscellaneous pediatrie disorders Vascular diseases Proliferative vasculopathy and hydranencephaly-hydrocephaly (Fowler syndrome) Meningocerebral angiodysplasia and renal agenesis Aneurysm of the vein of Galen Takayasu s arteritis Kawasaki disease (mucocutaneous lymph node syndrome) Hemolytic-uremic syndrome Hemorrhagic shock and encephalopathy syndrome Epilepsy in childhood Rasmussens encephalitis Hemiconvulsions-hemiplegia-epilepsy (HHB syndrome (acute postconvulsive hemiplegia) Progressive myodonic epilepsies An approach to the neuropathology of fatal pediatric trauma 144 147 148 148 148 150 153 153 157 157 157 157 157 159 161 161 161 162 162 164 164 166 Vascular disorders Chapter 8 Adult hypoxic and ischemic lesions Terminology Pathophysiologic considerations Pathology 171 171 172 172 Chapter 9 Vascular disease and infarcts 183 Large arterial disease 185 Atherosclerosis 185 Fibromuscular dysplasia (FMD) 190 Moyamoya disease 190 Arterial dissection 192 Human immunodeficiency virus (HIV)-associated stroke 192 Cerebrovascular disease associated with antiphospholipid antibody 195 Angiitis and vasculitis affecting large arteries 195 Giant cell arteritis (GCA) 195 Takayasu s arteritis 195 Pathologic findings after endovascular interventions 195 Small vessel disease (microangiopathy) 196 Angiitis and vasculitis 198 Primary angiitis of the CNS (PACNS) 198 Angiitis due to miscellaneous vasculitides 199 Microvasculopathies associated with dementia 201 Miscellaneous (sporadic) microangiopathies 206 Embolie diseases (stroke) 210 Cerebral venous (sinus) thrombosis (CVT) 214 CNS infarction 217 Infarcts caused by (thromboembolic) occlusion of large arteries 223 Spinal cord infarction 223 Foix—Alajouanine syndrome (angiodysgenetic myelomalacia) 223 Watershed or borderzone infarcts 228 Lacunar infarcts (lacunes) 228 Chapter 10 Hemorrhage 233 Extradural (epidural) hemorrhage (EDH) 233 Subdural hemorrhage/hematoma (SDH) 234 Subarachnoid hemorrhage/hematoma (SAH) 236 Berry (saccular) aneurysm 236 Infective aneurysm (IA) 238 Fusiform aneurysms 241 Other causes of SAH 242 Encephalic or intraparenchymal BH 243 Hypertensive BH 243 BH in malignant hypertension (MH) 246 Cerebral amyloid (congophilic) angiopathy (CAA) 248 Vascular malformations 253 Arteriovenous malformation (AVM) 253 Cavernous hemangioma (cavemoma) 257 vu Neuropathology Venous angioma Capillary telangiectasia Arteriovenous fistula BH secondary to systemic disease or medical therapy Β Η secondary to illicit drug use BH secondary to nonvascular pathologies 260 262 262 262 264 265 Chapter 11 Head and spinal injuries Head injury Nature of lesions in head injury Non-missile head injury Focal damage Infection Diffuse damage Traumatic axonal injury (TAD Diffuse vascular injury Brain swelling and raised intracranial pressure Ischemie damage Missile head injury Chrogic traumatic encephalopathy Spinal injury Traumatic spinal cord injury Non-traumatic spinal cord injury 271 271 271 272 272 279 280 280 287 287 290 292 293 294 294 296 Sections: Infectious disease Chapter 12 Acute viral infections Aseptic meningitis Poliomyelitis Neonatal enteroviral encephalitis Herpesvirus infections Herpes simplex virus infection Atypical herpes simplex encephalitis Chronic granulomatous herpes simplex encephalitis Necrotizing myeiopathy Neonatal HSV encephalitis Varicella-zoster virus (VZV) infection Epstein-Barr virus (EBV) infection Cytomegalovirus (CMV) infection Human herpesviruses 6 and 7 В virus Adenovirus Paramyxoviruses Rubella encephalitis 305 305 305 308 308 308 310 312 312 313 313 316 317 318 319 319 319 320 Rabies 320 Arbovirus infections 321 Chapter 13 Chronic and subacute viral infections of the CNS 327 Chronic enteroviral encephalomyelitis 327 Subacute measles encephalitides 327 Measles inclusion body encephalitis 327 Subacute sclerosing panencephalitis (SSPE) 329 Chronic granulomatous herpes simplex encephalitis 329 Progressive rubella panencephalitis 329 Progressive multifocal leukoencephalopathy (PML) 329 Human Τ cell leukemia/lymphotropic virus-1 (HTLV-1 )- associated myeiopathy (HAM) (tropical spastic paraparesis) 333 Human immunodeficiency virus (HIV) infection 333 Direct HIV infection of the CNS 335 HlV-associated immunosuppression and neurologic disease 342 HlV-associated systemic factors and miscellaneous conditions causing neurologic disease 348 Complications of HIV treatment that cause neurologic disease 349 Rasmussen s encephalitis 349 Chapter 14 Rickettsial and mycopłasma infections 357 Rickettsiae 357 Mycoplasma 358 Chapter 15 Acute bacterial infections and bacterial abscesses 361 Acute bacterial meningitis 361 Neonatal bacterial meningitis 361 Acute bacterial meningitis in children and adults 362 Brain abscess 365 Subdural empyema 370 Epidural abscess 370 Chapter 16 Chronic bacterial infections and neurosarcoidosis 373 Tuberculosis 373 Tuberculomas of the CNS 375 Spinal epidurai tuberculosis 376 Syphilis 376 Classification 376 Syphilitic meningitis 377 Meningovascular syphilis 377 General paresis (of the insane) 377 Tabes dorsalis 378 Gummatous neurosyphilis 379 Congenital neurosyphilis 380 CONTENTS ІХ Lyme neuroborreliosis Neurosarcoidosis Idiopathic hypertrophie pachymeningitis Whipple s disease Chapter 17 Fungal infections Filamentous fungi (molds) Aspergillosis Mucormycosis/zygomycosis Fusarium infection Pseudoallescheria boydii infection Phaeohyphomycosis Yeasts Cryptococcosis Candidiasis Dimorphic fungi North American blastomycosis Coccidioidomycosis Histoplasmosis Paracoccidioidomycosis Sporotrichosis Chapter 18 Parasitic infections Protozoa! infections Introduction Amebie infections Cerebral amebie abscess Primary amebie meningoencephalitis Granulomatous amebie encephalitis Cerebral malaria Cerebral toxoplasmosis Postnatally-acquired cerebral toxoplasmosis Congenital toxoplasmosis Trypanosomiasis African trypanosomiasis (sleeping sickness) American trypanosomiasis (Chagas disease) Microsporidiosis Helminthic infections Cestodes Nematodes Trematodes Demyelinating diseases Chapter 19 Multiple sclerosis Multiple sclerosis (MS) Classic (Charcot-type) MS 380 380 382 383 385 387 387 388 390 391 391 392 392 394 395 395 396 398 399 400 403 403 403 403 403 405 405 407 409 409 411 412 412 414 414 415 415 420 422 427 427 428 Acute (Marburg-type) MS 436 Concentric sclerosis (Baló s disease) 436 Chapter 20 Other demyelinating diseases: inflammatory and compressive 443 Neuromyelitis optica (Déviťs disease) 443 Acute disseminated encephalomyelitis (ADEM) 444 Acute hemorrhagic leukoencephalopathy (AHL) 446 Trigeminal neuralgia (TN) 446 Other syndromes of hyperactivity or abnormal spread of activity associated with vascular compression 450 Nutritional and metabolic disorders Chapter 21 Vitamin deficiencies 453 Thiamine deficiency and Wernicke s encephalopathy 453 Nicotinic acid deficiency and pellagra 454 Pyridoxine (vitamin B6) 454 Vitamin B12 (cobalamin) deficiency and subacute combined degeneration (SACD) 456 Folie acid deficiency 457 Vitamin A deficiency and intoxication 457 Vitamin D 458 Vitamin E (a-tocopherol) 459 Chapter 22 Systemic metabolic diseases 463 Introduction 463 Hypoglycémie 463 Findings in long-term survivors of severe hypoglycémie 464 Disturbances of body temperature 465 Hypothermia 465 Hyperthermia 465 Disorders of serum electrolytes 466 Hyponatremia 466 Hypernatremia 467 Osmotic demyelination syndrome 467 Calcium disturbances and Fahr s disease 469 Hypercalcémie encephalopathy 470 Liver disease 471 Acquired hepatic encephalopathy 471 Hepatolenticular degeneration (Wilson s disease) 472 Aceruloplasminemia 473 Other, rare causes of brain iron accumulation 473 Reye syndrome 473 Porphyria 474 Pancreatic disease 474 Pancreatic encephalopathy 474 ilHtiSiteS ififtiy. - ■.··■■■.■■ , —;--------------------------------------------———----------------------- Cystic fibrosis 475 Arsenic 515 Gastrointestinal disorders 475 Bismuth 522 Čeliac disease 475 Lead 522 Crohn s disease and ulcerative colitis 476 Manganese 523 Renal disease 476 Mercury 523 Uremie encephalopathy 476 Thallium 524 Dialysis encephalopathy 476 Tin 524 Multifocal necrotizing leukoencephalopathy (MNL) 476 Other industrial chemicals 526 Acrylamide 526 Chapter 23 Lysosomal and peroxisomal disorders 479 Carbon disulfide 526 Lysosomal disorders 479 Carbon tetrachloride 526 GM2 Gangliosidosis 479 Ethylene glycol 527 GM] Gangliosidosis 480 Ethylene oxide 527 Galactosialidosis 480 Hexacarbon solvents (N-hexane and methyl /V-butyl ketone) 527 Batten s disease, neuronal ceroid lipofuscinosis (NCL, CLN) 481 Methanol 528 Niemann-pick disease 482 Organophosphates 529 Gaucher s disease 486 /V-S-Pyridylmethyl-A/ -p-nitrophenyl urea (PNU) 530 Mucopolysaccharidoses (MPS) 487 Toluene 530 Mannosidosis 489 Toxic oil syndrome and eosinophilia-myalgia syndrome 531 Fucosidosis 489 Trichlorethylene (TCE) 531 Fabry s disease 489 Gases 531 Type II glycogenosis (Pompe s disease) 491 Carbon monoxide 531 Farber s disease 491 Cyanide 533 Krabbe s leukodystrophy 492 Nitrous oxide 533 Metachromatic leukodystrophy (MLD) 493 Antiviral, antibacterial, antifungal, and antiprotozoa! drugs 534 Peroxisomal disorders 493 Amphotericin В 534 Zellweger cerebrohepatorenal syndrome 495 Clioquinol 534 Adrenoleukodystrophy 496 Hexachlorophene (USAWhexachlorophane (UK) 534 Melarsoprol 534 Chapter 24 Mitochondrial encephalopathies 499 Vidarabine (adeninę arabinoside, ARA-A) 534 Mitochondrial myopathy, encephalopathy, lactic acidosis, Miscellaneous antibiotics 535 and stroke-like episodes (MELAS) 501 Antineoplastic and immunosuppressive agents 535 Myoclonic epilepsy with ragged-red fibers (MERRF) 502 Alkylating agents 535 Leber s hereditary optic neuropathy (LHON), bilateral striatal L-asparaginase 535 necrosis, and multiple sclerosis (MS) like mitochondrial disease 505 1,3-Bis(2-chloroethyD- 1 -nitrosourea (BCNU) 535 Bilateral striatal necrosis 505 Calcineurin inhibitors: cyclosporine A (CSA) and tacrolimus Neuropathy, ataxia, and retinitis pigmentosa (NARP) 506 (FK506) 535 Keams-Sayre syndrome (KSS), and chronic progressive Methotrexate 536 external ophthalmoplegia (CPEO) 507 Cisplatin 536 Myoneurogastrointestinal encephalopathy (MNGIB syndrome 509 Nudeoside analogs 537 Mitochondrial DNA breakage syndrome 510 Vincristine ■53Я Hepatocerebral form of mitochondrial DNA depletion syndrome 510 Miscellaneous therapeutic or diagnostic drugs J JO 538 ^^^^ДД Toxic injury Lithium 538 Chapter 25 Toxic injury of the CNS 515 ivieinzomiae Phenytoin 538 538 Metals 515 Street drugs 539 Aluminum (aluminium) 515 Amphetamines 539 CONTENTS ХІ Cocaine Heroin (diamorphine) MPTP (1 -methyM-phenyl-U^ó-tetrahydropyridine) Ethanol ( alcohol ) CNS effects of acute ethanol intoxication CNS effects of chronic alcoholism Cerebral atrophy Cerebellar degeneration Marchiafava-Bignami disease Morel s laminar sclerosis Fetal alcohol syndrome Biologic toxins Clostridium botulinum exotoxin Corynebacterium diphtheriae exotoxin Clostridium tetani exotoxin Cycad toxin Lathyrus toxin Domoic acid Snake and scorpion venoms 539 540 540 541 541 541 542 542 543 543 543 544 544 544 544 544 544 544 544 Neurodegenerative diseases Chapter 26 Classification and pathogenesis of neurodegenerative diseases 549 Classification 549 Pathogenesis 549 Protein accumulation and degradation 550 Oxidative stress and mitochondrial integrity 551 Excitotoxicity 551 Induction of programmed cell death 551 Role of cytokines and neuroinflammation 551 Genetic factors 551 Aging and neurodegeneration 553 Chapter 27 Motor neuron disorders 555 Classification 555 Amyotrophic lateral sclerosis (ALS) 555 Nomenclature 555 Extra-motor involvement in ALS 561 Juvenile ALS with basophilic inclusions 561 Х -linked bulbospinal neuronopathy (spinobulbar muscular atrophy, Kennedy s disease) 561 Spinal muscular atrophy (SMA) 562 Autosomal recessive SMA 562 Adult-onset SMA 563 Spinal muscular atrophy with respiratory distress 563 Bulbospinal muscular atrophy 563 Fazio-Londe disease Brown-Vialetto-Van Laere syndrome Hereditary spastic paraparesis Chapter 28 Parkin sonism and akinetic—rigid disorders Parkinson s disease (PD) Lewy bodies Juvenile parkinsonism Drug and toxin-related parkinsonism Progressive supranuclear palsy (PSP) (Steele-Richardson- Olszewski syndrome) Postencephalitic parkinsonism Multiple system atrophy (MSA) Corticobasal degeneration (CBD) Arteriosclerotic pseudoparkinsonism Guam parkinsonism-dementia Chapter 29 Ataxie disorders Neuropathological changes in degenerative causes of ataxia Cerebellar cortical degeneration Olivopontocerebellar atrophy (OPCA) Autosomal recessive cerebellar ataxia Friedreich s ataxia (FA) Cerebellar ataxia with isolated vitamin E deficiency Mitochondrial recessive ataxia syndrome Ataxia-telangiectasia (AT) Ataxia-telangiectasia-like disorder Autosomal dominant cerebellar ataxia Dentatorubropallidoluysial atrophy (DRPLA) Х -linked ataxias Fragile -Х tremor/ataxia syndrome (FXTAS) Non-hereditary degenerative ataxias Multiple system atrophy Sporadic adult-onset ataxia of unknown etiology (SAOA) 563 564 564 567 567 568 572 573 573 575 576 579 583 584 587 587 588 588 588 588 591 591 591 592 592 593 593 595 596 596 596 Chapter 30 Hyperldnetic movement disorders 599 Chorea 599 Huntington disease (HD) 599 Neuroacanthocytosis 602 Myoclonus 602 Ballismus and hemiballismus 602 Dystonia 606 Chapter 31 Dementias 609 Introduction 609 xü Neuropathoiogy Temporoparietal and frontotemporoparietal dementias 610 Alzheimer s disease (AD) 610 Histopathology of Alzheimer s Disease 611 Difficulties in diagnosing AD 627 Lewy bodies in dementia syndromes 628 Dementia with Lewy bodies (DLB) 629 Parkinson s disease dementia (PDD) 631 Frontotemporal lobar degenerations, including tauopathies 631 Pathologic subtypes of FTLD 633 The tauopathies including FTLD-tau 634 Pick s disease: clinical features 635 Frontotemporal degeneration and parkinsonism linked to chromosome 17 tau (FTDP-tftau) 636 Dementia with changes of CBD or PSP 637 Tangle-only dementia 639 Rare geographically restricted tauopathies 639 Argyrophilic grain dementia (AGD) 639 Frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) 639 Neuronal intermediate filament inclusion disease (NIFID) 644 Hippocampal sclerosis 647 Familial British dementia and familial Danish dementia 647 Dementia with neuroserpin accumulation 649 Dementia associated with other degenerative diseases 649 Thafamic dementias 649 Vascular dementia 649 Mixed dementia (vascular and Alzheimer s disease) 653 Neuropathologic assessment in vascular dementia 653 Intermittently raised pressure hydrocephalus 653 Brain biopsy in dementia 654 A staged approach to pathologic diagnosis 654 Chapter 32 Prion diseases 659 Pathology 665 Sporadic OD 671 Gerstmann-Sträussler-Scheinker disease (GSS) 671 Fatal familial insomnia (FFI) 673 Sporadic fatal insomnia 673 Variant OD (VC1D) 673 latrogenic OD 673 Panencephalopathic CID 673 Kuru 673 Pitfalls in the histopathological diagnosis of prion disease 676 Chapter 33 Thalamk and pallidal degenerations, neuroaxonal dystrophy, and autonomie fatture Thalamic degenerations Pure thalamic atrophy Pallidal degenerations Neuroaxonal dystrophy Classification Physiologic neuroaxonal dystrophy Primary neuroaxonal dystrophy Neuroaxonal leukodystrophy Pantothenate kinase-associated neurodegeneration (formerly Hallervorden-Spatz disease) Nasu-Hakola disease Giant axonal neuropathy Secondary neuroaxonal dystrophy Central autonomie failure Introduction and classification Shy-Drager syndrome Pure progressive autonomie failure Bradbury-Eggleston syndrome Section 10: Neoplasms Chapter 34 Classification and genen CNS neoplasms CNS neoplasms The pathologist and CNS neoplasms eptsof 681 681 681 681 682 682 682 682 682 686 686 686 691 691 691 692 692 692 697 697 698 705 Chapter 35 Astrocytk neoplasms Diffuse astrocytic neoplasms - astrocytoma, anaplastic astrocytoma, glioblastoma 705 Genetics, malignant progression, and grading of astrocytic neoplasms 705 Astrocytoma 709 Anaplastic astrocytoma 711 Glioblastoma 711 Gliomatosis cerebri 715 Pilocytic astrocytoma 718 Pteomorphic xanthoastrocytoma 723 Subependymal giant cell astrocytoma (SEGA) and tuberous sclerosis complex (TSO 725 Chapter 36 Non-astrocytk двотаѕ 729 Oligodendrogliomas 729 Ependymomas 732 Mixed gliomas 737 CONTENTS ХІІІ Chapter 37 Neuroepithelial neoplasms displaying neuronal features 743 Gangliocytoma and ganglioglioma 743 Desmoplastic infantile ganglioglioma (DIGG) 746 Central and extraventricular neurocytoma 746 Cerebellar liponeurocytoma 747 Papillary glioneuronal tumor 748 Rosette-forming glioneuronal tumor of the fourth ventricle 748 Paraganglioma of the filum terminale 748 Dysembryoplastic neuroepithelial tumor (DNT) 750 Dysplastic gangliocytoma of the cerebellum 752 Hypothalamic neuronal hamartoma 753 Chapter 38 Embryonal neuroepithelial neoplasms of the CNS 755 Embryonal neuroepithelial neoplasms 755 Chapter 39 Neoplasms of the pineal gland 769 Pineal parenchymal neoplasms 769 Papillary tumor of the pineal region 771 Pineal cyst 772 Primary CNS germ cell neoplasms 773 Germinomas 773 Embryonal carcinoma, yolk sac tumor, and choriocarcinoma 775 Teratomas 776 Chapter 40 Choroid plexus neoplasms 783 Choroid plexus neoplasms 783 Chapter 41 Primary CNS h/mphomas 789 Chapter 42 Peripheral nerve sheath neoplasms 797 Schwannomas 797 Neurofibromas 801 Malignant nerve sheath tumors 802 Chapter 43 Meningiomas 805 Meningiomas 805 Chapter 44 Neoplasms in the region of the pituitary fossa 819 Pituitary adenomas 819 Pituitary hyperplasia Craniopharyngiomas Rathke cleft cyst Granular cell neoplasm of the infundibulum Pituicytoma Spindle cell oncocytoma of the adenohypophysis Chapter 45 Miscellaneous CNS neoplasms and cysts Glial tumors of uncertain origin Astroblastoma Angiocentric glioma Chordoid glioma of the third ventricle Mesenchymal non-meningothelial neoplasms Osteocartilaginous neoplasms of the meninges Lipoma Solitary fibrous tumor of the meninges Vasoformative neoplasms Hemangiopericytoma Sarcomas Melanocytic neoplasms Hemangioblastoma Cysts Epidermoid and dermoid cysts Colloid cyst of the third ventricle Endodermal cyst Ependymal cyst Arachnoid cyst Chapter 46 Neoplasms that spread to the CNS Neoplasms in tissues surrounding the CNS Secondary neoplasms in the meninges Secondary neoplasms in the brain and spinal cord Chapter 47 Pa »plastic dbordc Paraneoplastic encephalomyelitis Paraneoplastic cerebellar degeneration (PCD) Paraneoplastic opsodonus-myoclonus-ataxia Glossary Index 827 827 831 832 832 833 835 835 835 836 836 836 837 837 837 839 840 840 842 843 845 845 846 846 847 847 849 850 850 852 857 858 858 858 861 863 A REFERENCE TEXT OF CNS PATHOLOGY NEUROPATHOLOGY Improve your diagnostic accuracy with the most extensively illustrated neuropathology reference available! More than 3,000 high-quality images - nearly all in full color - provide an unmatched visual guide to both microscopic and gross pathology. • Understand the latest developments in neurologic diseases and quickly identify important variants and outliers. • Meet the needs of an aging population with expanded coverage of neurodegenerative diseases that affect brain and movement functions, including Alzheimer s disease, Parkinson s disease, motor neuron disorders, and prion diseases, as well as conditions such as multiple sclerosis. • Gain a new perspective on hot topics such as molecular genetics and the growing role of genetic testing. • Make the most of the latest functional imaging techniques with new information on PET, fMRI, and SPECT. • Stay current with the latest diagnostic protocols and guidelines as endorsed by professional societies and national bodies, the most recent WHO classification of central nervous system diseases, and checklists for the handling and diagnosis of CNS tumors and tumor-like lesions. • Access the complete contents online and download all the images at
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illustrated	Illustrated
indexdate	2024-07-10T00:28:29Z
institution	BVB
isbn	0723435154 9780723435150
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-025485995
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physical	XIII, 879 S. zahlr. Ill., graph. Darst.
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publisher	Mosby, Elsevier
record_format	marc
spelling	Neuropathology a reference text of CNS pathology David Ellison ... 3. ed. Edinburgh [u.a.] Mosby, Elsevier 2013 XIII, 879 S. zahlr. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Neurologie gtt Neuropathologie gtt Zenuwstelsel gtt Zenuwstelselaandoeningen gtt Nervous System Diseases pathology Nervous system Diseases Nervous system Diseases Diagnosis Pathologie (DE-588)4044893-9 gnd rswk-swf Zentralnervensystem (DE-588)4067637-7 gnd rswk-swf Neuropathologie (DE-588)4171594-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content (DE-588)4151278-9 Einführung gnd-content Zentralnervensystem (DE-588)4067637-7 s Pathologie (DE-588)4044893-9 s DE-604 Neuropathologie (DE-588)4171594-9 s Ellison, David Sonstige oth Erscheint auch als Online-Ausgabe 978-0-7234-3746-8 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025485995&sequence=000005&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025485995&sequence=000006&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext
spellingShingle	Neuropathology a reference text of CNS pathology Neurologie gtt Neuropathologie gtt Zenuwstelsel gtt Zenuwstelselaandoeningen gtt Nervous System Diseases pathology Nervous system Diseases Nervous system Diseases Diagnosis Pathologie (DE-588)4044893-9 gnd Zentralnervensystem (DE-588)4067637-7 gnd Neuropathologie (DE-588)4171594-9 gnd
subject_GND	(DE-588)4044893-9 (DE-588)4067637-7 (DE-588)4171594-9 (DE-588)4143413-4 (DE-588)4151278-9
title	Neuropathology a reference text of CNS pathology
title_auth	Neuropathology a reference text of CNS pathology
title_exact_search	Neuropathology a reference text of CNS pathology
title_full	Neuropathology a reference text of CNS pathology David Ellison ...
title_fullStr	Neuropathology a reference text of CNS pathology David Ellison ...
title_full_unstemmed	Neuropathology a reference text of CNS pathology David Ellison ...
title_short	Neuropathology
title_sort	neuropathology a reference text of cns pathology
title_sub	a reference text of CNS pathology
topic	Neurologie gtt Neuropathologie gtt Zenuwstelsel gtt Zenuwstelselaandoeningen gtt Nervous System Diseases pathology Nervous system Diseases Nervous system Diseases Diagnosis Pathologie (DE-588)4044893-9 gnd Zentralnervensystem (DE-588)4067637-7 gnd Neuropathologie (DE-588)4171594-9 gnd
topic_facet	Neurologie Neuropathologie Zenuwstelsel Zenuwstelselaandoeningen Nervous System Diseases pathology Nervous system Diseases Nervous system Diseases Diagnosis Pathologie Zentralnervensystem Aufsatzsammlung Einführung
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025485995&sequence=000005&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025485995&sequence=000006&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT ellisondavid neuropathologyareferencetextofcnspathology

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