Interstitial lung disease and autoimmune lung diseases:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia, Pa.
Elsevier
2012
|
| Schriftenreihe: | Immunology and allergy clinics of North America
32,4 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV S., S. 454 - 684 Ill., graph. Darst. |
| ISBN: | 9781455748464 |
Internformat
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| 245 | 1 | 0 | |a Interstitial lung disease and autoimmune lung diseases |c ed.: Kevin K. Brown ... |
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Datensatz im Suchindex
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| adam_text | Interstitial Lung Disease and Autoimmune Lung Diseases
Contents
Preface
xi
Kevin K. Brown, Aryeh Fischer, and Jeffrey J. Swigris
Foreword: Interstitial Lung Diseases
xiii
Rafeul
Alam
A Clinical Approach to Diffuse Parenchymal Lung Disease
453
Toby M. Maher
The diffuse parenchymal lung diseases (DPLDs) are a group of more than
200
diverse conditions; therefore achieving an exact diagnosis is fre¬
quently challenging. However, with the advent of novel, disease-specific
therapies, an accurate diagnosis in DPLD is of growing importance. The
recognition that many of the DPLDs have distinctive high-resolution com¬
puted tomography appearances has greatly reduced the need for biopsy,
although in cases of uncertainty,
histologie
assessment remains an impor¬
tant tool. Ultimately, the diagnostic assessment of DPLD is best under¬
taken through an interstitial lung disease multidisciplinary team meeting
that brings together physicians, thoracic radiologists, and pathologists.
Idjopathic Pulmonary Fibrosis
473
Jason S. Zolak and
João A. de Andrade
Idiopathic pulmonary fibrosis (IPF) isachronic lung disease of unknown cause
characterized by progressive scarring of the lung parenchyma and relentless
loss of lung function. The diagnosis depends on close collaboration between
clinicians, radiologists, and pathologists. No therapies approved by the Food
and Drug Administration are available for IPF, and an analysis of completed
clinical trials has demonstrated that the clinical course of IPF is largely unpre¬
dictable. Until therapies that improve survival become available, measures to
preserve function and quality of life should be considered, and gastroesoph-
ageal reflux should be treated aggressively.
Sarcoidosis
487
Daniel A. Culver
Sarcoidosis is a multisystem granulomatous syndrome with a vast range of
clinical manifestations. Since the first description of sarcoidosis in
1869,
it
has simultaneously intrigued and perplexed generations of physicians. Be¬
cause sarcoidosis can occur variably in any organ and does not always ad¬
here to classic descriptions, both diagnosis of sarcoidosis and attribution
of symptoms can be extremely challenging. The management of sarcoid¬
osis requires consideration of the expected course. Medication is consid¬
ered when there is risk of irreversible vital organ damage, substantial
progression, or symptoms that are affecting quality of
ufe.
Recently,
a range of steroid-sparing therapies have been adopted for sarcoidosis.
viii Contents
Connective Tissue Disease-Associated Lung Disease
513
Amy
L
Olson, Kevin K. Brown, and Aryeh Fischer
This article provides a broad overview of the complex intersection be¬
tween the connective tissue diseases (CTDs) and their pulmonary
manifestations. Indirect pulmonary complications
-
such as respiratory
infection and medication-induced lung
toxicity
-
are briefly discussed,
and the importance of a comprehensive assessment of the patient
with CTD with respiratory symptoms is emphasized. A concise review
of the many pulmonary manifestations of each specific CTD is pro¬
vided, and particular emphasis is placed on CTD-associated interstitial
lung disease.
Hypersensitivity Pneumonitis
537
Shinichiro Ohshimo, Francesco Bonella, Josune Guzman, and
Ulrich Costabel
Clinical manifestations of hypersensitivity pneumonitis may closely mimic
other interstitial lung diseases, and the disease onset is usually insidious.
High-resolution computed tomography and bronchoalveolar
lavage
are
the sensitive and characteristic diagnostic tests for hypersensitivity pneu¬
monitis. The relevant antigen to hypersensitivity pneumonitis cannot be
identified in up to
20%
to
30%
of patients. Clinicians should be aware
that hypersensitivity pneumonitis must be considered in all cases of inter¬
stitial lung disease, and a detailed environmental exposure history is
mandatory.
Eosinophilic Lung Diseases
557
Vincent Cottin and
Jean-François Cordier
Eosinophilic lung diseases comprise eosinophilic pneumonia, which may
present with chronic or acute onset, or as
Löffler
syndrome. The diag¬
nosis of eosinophilic pneumonia relies on clinical imaging and the de¬
monstration of alveolar eosinophilia. Lung biopsy is generally not
necessary. Peripheral blood eosinophilia is common but may be absent
at presentation in idiopathic acute eosinophilic pneumonia, which may
be misdiagnosed as severe infectious pneumonia. Extra-thoracic mani¬
festations should raise the suspicion of Churg-Strauss syndrome. All
possible causes of eosinophilia (especially fungus infection or drug or
toxic exposure) must be thoroughly investigated before the diagnosis
of idiopathic disease is made.
Update on Diffuse Alveolar Hemorrhage and Pulmonary Vasculitis
587
Megan
L
Krause,
Rodrigo Cartin-Ceba, Ulrich
Specks, and Tobias Peikert
Diffuse alveolar hemorrhage is a clinical syndrome that can be a manifes¬
tation of multiple different causes. Identification of the underlying etiology
is of utmost importance and dictates treatment. Pulmonary vasculitis in¬
cluding antineutrophil cytoplasmic antibody (ANCAj-associated vasculitis
(AAV) is a common cause of diffuse alveolar hemorrhage. For AAV, treat¬
ment includes induction followed by maintenance therapy. Rituximab has
an increasing role in the treatment of AAV.
Contents ix
Bronchiolitis 601
Brian T. Garibaldi, Peter Illei, and Sonye K. Danoff
Bronchiolitis
is a disease of the small airways accompanied by progressive
and often irreversible airflow obstruction. Bronchiolitis can have several
causes such as infection, toxic exposure, collagen vascular disease,
post lung and stem cell transplant, and idiopathic etiology. Symptoms of
cough and sputum production are often mistaken for chronic obstructive
pulmonary disease or asthma, leading to a delay in diagnosis. Unfortu¬
nately, many types of bronchiolitis do not improve with therapy. Bronchio¬
litis following lung and stem cell transplant are the most common types
seen in adults, and provide important insights into its pathogenesis.
Granulomatous Lymphocytic Interstitial Lung Disease
621
Evans R.
Fernández Pérez
As the use of high-dose intravenous gamma globulin and available antimi¬
crobials expands, the incidence of noninfectious common variable immu¬
nodeficiency-related disorders, such as granulomatous-lynnphocytic
interstitial lung disease (GLILD), is likely to increase. A thorough clinical
evaluation using a multidisciplinary care model is recommended to
achieve accurate diagnosis of GLILD. Enough progress has been made
in the understanding of GLILD over the last decade that clinicians are
now poised to conduct therapeutic trials. Data from large registries and
population-based studies of GLILD are needed to better understand the
disease trends and burden. This article focuses on the diagnosis and man¬
agement of GLILD.
Immunosuppressive Therapy for Autoimmune Lung Diseases
633
Keith C. Meyer and Jennifer Bierach
This article focuses on issues of safety and monitoring when immunosup¬
pressive
pharmacologie
therapies are prescribed for the treatment of
connective tissue disease (CTDi-associated interstitial pneumonias, vas-
culitides, and bronchiolitis. Prospective, randomized placebo-controlled
clinical trials have yet to be performed to evaluate the efficacy and safety
of various immunosuppressive agents used to treat patients with CTD-
interstitial lung disease or idiopathic interstitial pneumonias other than
idiopathic pulmonary fibrosis (idiopathic usual interstitial pneumonia) that
are not associated with the presence of CTD. Knowledge of their potential
toxicities and interactions with other drugs combined with the adoption of
a systematic approach to monitoring therapy can minimize life-threatening
reactions.
Index
671
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| series | Immunology and allergy clinics of North America |
| series2 | Immunology and allergy clinics of North America Clinics review articles |
| spelling | Interstitial lung disease and autoimmune lung diseases ed.: Kevin K. Brown ... Philadelphia, Pa. Elsevier 2012 XIV S., S. 454 - 684 Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Immunology and allergy clinics of North America 32,4 Clinics review articles Lunge (DE-588)4036651-0 gnd rswk-swf Autoaggressionskrankheit (DE-588)4003935-3 gnd rswk-swf Interstitielle Lungenkrankheit (DE-588)4239847-2 gnd rswk-swf Interstitielle Lungenkrankheit (DE-588)4239847-2 s DE-604 Lunge (DE-588)4036651-0 s Autoaggressionskrankheit (DE-588)4003935-3 s Brown, Kevin K. Sonstige oth Immunology and allergy clinics of North America 32,4 (DE-604)BV000645505 32,4 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025465482&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Interstitial lung disease and autoimmune lung diseases Immunology and allergy clinics of North America Lunge (DE-588)4036651-0 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd Interstitielle Lungenkrankheit (DE-588)4239847-2 gnd |
| subject_GND | (DE-588)4036651-0 (DE-588)4003935-3 (DE-588)4239847-2 |
| title | Interstitial lung disease and autoimmune lung diseases |
| title_auth | Interstitial lung disease and autoimmune lung diseases |
| title_exact_search | Interstitial lung disease and autoimmune lung diseases |
| title_full | Interstitial lung disease and autoimmune lung diseases ed.: Kevin K. Brown ... |
| title_fullStr | Interstitial lung disease and autoimmune lung diseases ed.: Kevin K. Brown ... |
| title_full_unstemmed | Interstitial lung disease and autoimmune lung diseases ed.: Kevin K. Brown ... |
| title_short | Interstitial lung disease and autoimmune lung diseases |
| title_sort | interstitial lung disease and autoimmune lung diseases |
| topic | Lunge (DE-588)4036651-0 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd Interstitielle Lungenkrankheit (DE-588)4239847-2 gnd |
| topic_facet | Lunge Autoaggressionskrankheit Interstitielle Lungenkrankheit |
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