Natural Products and Cancer Drug Discovery:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Humana Press
2013
|
| Schriftenreihe: | Cancer Drug Discovery and Development
|
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext Inhaltsverzeichnis Abstract |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9781461446538 9781461446545 |
| DOI: | 10.1007/978-1-4614-4654-5 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804149749104771072 |
|---|---|
| adam_text | NATURAL PRODUCTS AND CANCER DRUG DISCOVERY
/
: 2013
TABLE OF CONTENTS / INHALTSVERZEICHNIS
PREFACE.- THE IMPACT OF NATURAL PRODUCTS UPON CANCER CHEMOTHERAPY
IDENTIFICATION AND DEVELOPMENT OF VASCULAR DISRUPTING AGENTS: NATURAL
PRODUCTS THAT INTERFERE WITH TUMOR GROWTH
DISCODERMOLIDE: PAST, PRESENT AND FUTURE
HDAC INHIBITORS AND OTHER HISTONE MODIFYING NATURAL PRODUCTS AS EMERGING
ANTICANCER AGENTS
NATURAL PRODUCT CYTOTOXINS AS PAYLOADS FOR ANTIBODY DRUG CONJUGATES
NATURAL PRODUCT SCAFFOLDS IN CANCER THERAPY
THE ROLE OF GENETIC ENGINEERING IN NATURAL PRODUCT-BASED ANTICANCER DRUG
DISCOVERY
ACCESSING ANTI-CANCER NATURAL PRODUCTS BY PLANT CELL CULTURE
NATURAL PRODUCTS AS TOOLS FOR DISCOVERING NEW CANCER TARGETS
INDEX
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
NATURAL PRODUCTS AND CANCER DRUG DISCOVERY
/
: 2013
ABSTRACT / INHALTSTEXT
NATURAL PRODUCTS- COMPOUNDS DERIVED FROM PLANTS, MICROBES AND MARINE
ORGANISMS, HAVE BEEN AN UNSURPASSED SOURCE OF CANCER DRUGS IN THE MODERN
ERA OF DRUG DISCOVERY. THE HISTORICAL RECORD IS STRONG, BUT WHAT IS
THE CURRENT IMPACT OF NATURAL PRODUCTS IN THE DISCOVERY AND
DEVELOPMENT OF CANCER DRUGS, AND IMPORTANTLY WHAT ARE THE PROSPECTS FOR
NATURAL PRODUCTS TO BE A VALUABLE SOURCE OF FUTURE AGENTS? THIS
VOLUME ATTEMPTS TO ADDRESS THIS QUESTION THROUGH A SERIES OF CHAPTERS
AUTHORED BY LEADING RESEARCHERS IN THE FIELD WHICH EFFECTIVELY PROVIDE
AN IN-DEPTH VIEW OF SEVERAL HIGH IMPACT AREAS OF NATURAL PRODUCTS CANCER
RESEARCH. THE VOLUME BEGINS WITH A FOCUSED ANALYSIS AND RATIONALE FOR
THE CLINICAL SUCCESS OF CURRENT NATURAL PRODUCT ANTI-CANCER DRUGS. THE
FOLLOWING CHAPTERS THEN DESCRIBE NEW NATURAL PRODUCT BASED DRUGS IN
THREE RAPIDLY EVOLVING TARGET CLASSES AND MODALITIES- AGENTS WHICH
TARGET TUMOR VASCULATURE, INHIBITORS OF HISTONE DEACETYLASE AND OTHER
HISTONE MODIFYING ENZYMES, AND ANTIBODY DRUG CONJUGATES. SUBSEQUENT
CHAPTERS EXAMINE THE CENTRAL ROLE OF NATURAL PRODUCT CHEMICAL SCAFFOLDS
IN THE GENESIS OF NEW ANTI-CANCER THERAPEUTICS- FIRST VIA THE POWERFUL
APPLICATION OF CHEMICAL SYNTHESIS, AND THEN THROUGH THE RAPIDLY
EMERGING FIELDS OF BIOSYNTHETIC ENGINEERING AND PLANT CELL CULTURE.
THE VOLUME CONCLUDES WITH AN ASSESSMENT OF THE CRITICAL ROLE THAT
NATURAL PRODUCTS CONTINUE TO PLAY IN THE SEARCH FOR NEW CANCER DRUG
TARGETS. AS THE READER MAKES HIS OR HER WAY THROUGH THE VOLUME IT MAY
BECOME CLEAR THAT THERE IS STRONG EVIDENCE THAT NATURAL PRODUCTS WILL
CONTINUE TO EXERT A PROFOUND POSITIVE IMPACT ON CANCER DRUG DISCOVERY
DIESES SCHRIFTSTUECK WURDE MASCHINELL ERZEUGT.
|
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| language | English |
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| series2 | Cancer Drug Discovery and Development |
| spelling | Natural Products and Cancer Drug Discovery Frank E. Koehn, ed. New York, NY Humana Press 2013 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Cancer Drug Discovery and Development Medizin Medicine Oncology Toxicology Biomedicine Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Naturheilmittel (DE-588)4288415-9 gnd rswk-swf Cytostatikum (DE-588)4068347-3 gnd rswk-swf Cytostatikum (DE-588)4068347-3 s Naturheilmittel (DE-588)4288415-9 s DE-604 Krebs Medizin (DE-588)4073781-0 s Koehn, Frank E. Sonstige oth https://doi.org/10.1007/978-1-4614-4654-5 Verlag Volltext Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025463261&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Springer Fremddatenuebernahme application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025463261&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Abstract |
| spellingShingle | Natural Products and Cancer Drug Discovery Medizin Medicine Oncology Toxicology Biomedicine Krebs Medizin (DE-588)4073781-0 gnd Naturheilmittel (DE-588)4288415-9 gnd Cytostatikum (DE-588)4068347-3 gnd |
| subject_GND | (DE-588)4073781-0 (DE-588)4288415-9 (DE-588)4068347-3 |
| title | Natural Products and Cancer Drug Discovery |
| title_auth | Natural Products and Cancer Drug Discovery |
| title_exact_search | Natural Products and Cancer Drug Discovery |
| title_full | Natural Products and Cancer Drug Discovery Frank E. Koehn, ed. |
| title_fullStr | Natural Products and Cancer Drug Discovery Frank E. Koehn, ed. |
| title_full_unstemmed | Natural Products and Cancer Drug Discovery Frank E. Koehn, ed. |
| title_short | Natural Products and Cancer Drug Discovery |
| title_sort | natural products and cancer drug discovery |
| topic | Medizin Medicine Oncology Toxicology Biomedicine Krebs Medizin (DE-588)4073781-0 gnd Naturheilmittel (DE-588)4288415-9 gnd Cytostatikum (DE-588)4068347-3 gnd |
| topic_facet | Medizin Medicine Oncology Toxicology Biomedicine Krebs Medizin Naturheilmittel Cytostatikum |
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