G-protein coupled receptors: methods express
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Bibliographische Detailangaben
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Chichester, West Sussex, UK John Wiley & Sons 2010
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Online-Zugang:TUM01
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Beschreibung:Includes bibliographical references and index
G Protein-Coupled Receptors; Contents; Preface; Contributors; 1 Measurement of Ligand-G Protein-coupled Receptor Interactions; 2 Second Messenger Assays for G Protein-coupled Receptors: cAMP, Ca2+, Inositol Phosphates, ERK1/2; 3 Use of the [35S]GTP?S Binding Assay to Determine Ligand Efficacy at G Protein-coupled Receptors; 4 Quantitative Imaging of Receptor Trafficking; 5 Production of Recombinant G Protein-coupled Receptor in Yeast for Structural and Functional Analysis; 6 Monitoring GPCR-Protein Complexes Using Bioluminescence Resonance Energy Transfer
G-Protein Coupled Receptors (GPCRs) are not only the largest protein family in the human genome but are also the single biggest target for therapeutic agents. Research into GPCRs is therefore growing at a fast pace and the range of techniques that can be applied to GPCRs is vast and continues to grow. This book provides an invaluable bench-side guide into the best and most up-to-date techniques for current and future research on GPCRs. With contributions from leading international authorities, this book equips readers with clear and detailed protocols for both well-known and up-and-coming tech
Beschreibung:1 Online-Ressource (xiv, 296 p.)
ISBN:0470749229
9780470749227

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