Serodiagnosis of glanders with reference to endemic and non-endemic settings:
Gespeichert in:
1. Verfasser: | |
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Format: | Abschlussarbeit Buch |
Sprache: | English |
Veröffentlicht: |
Berlin
Mensch-und-Buch-Verl.
2012
|
Schlagworte: | |
Online-Zugang: | Volltext Inhaltsverzeichnis |
Beschreibung: | Nebentitel: Serologische Diagnostik von Rotz unter Berücksichtigung endemischer und nicht-endemischer Tierseuchensituationen |
Beschreibung: | X, 92 S. Ill., Kt. |
ISBN: | 9783863871901 |
Internformat
MARC
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100 | 1 | |a Khan, Iahtasham |e Verfasser |4 aut | |
245 | 1 | 0 | |a Serodiagnosis of glanders with reference to endemic and non-endemic settings |c vorgelegt von Iahtasham Khan |
246 | 1 | 3 | |a Serologische Diagnostik von Rotz unter Berücksichtigung endemischer und nicht-endemischer Tierseuchensituationen |
264 | 1 | |a Berlin |b Mensch-und-Buch-Verl. |c 2012 | |
300 | |a X, 92 S. |b Ill., Kt. | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
500 | |a Nebentitel: Serologische Diagnostik von Rotz unter Berücksichtigung endemischer und nicht-endemischer Tierseuchensituationen | ||
502 | |a Berlin, Freie Univ., Diss., 2012 | ||
650 | 7 | |a emerging infectious diseases |2 cabt | |
650 | 7 | |a glanders |2 cabt | |
650 | 7 | |a horses |2 cabt | |
650 | 7 | |a diagnosis |2 cabt | |
650 | 7 | |a zoonoses |2 cabt | |
650 | 7 | |a serology |2 cabt | |
650 | 7 | |a epidemiology |2 cabt | |
650 | 7 | |a Pakistan |2 cabt | |
650 | 7 | |a Brazil |2 cabt | |
650 | 7 | |a Germany |2 cabt | |
650 | 4 | |a Pferd | |
650 | 0 | 7 | |a Rotz |0 (DE-588)4578160-6 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Serodiagnostik |0 (DE-588)4181044-2 |2 gnd |9 rswk-swf |
651 | 4 | |a Brasilien | |
651 | 4 | |a Deutschland | |
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912 | |a ebook | ||
999 | |a oai:aleph.bib-bvb.de:BVB01-025187384 |
Datensatz im Suchindex
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adam_text | IMAGE 1
TABLE O F CONTENTS
PAGE NO.
1 INTRODUCTION 1
2 LITERATURE 4
2.1 CHARACTERISATION O F BURKHOLDERIA MALLEI 4
2.1.1 HISTORY AND TAXONOMY 4
2.1.2 MICROBIOLOGICAL CHARACTERISTICS 4
2.1.3 ANTIBIOTIC RESISTANCE 6
2.1.4 BURKHOLDERIA MALLEI ANTIGEN 6
2.1.5 VIRULENCE FACTORS 7
2. 2 GLANDERS 8
2.2.1 HISTORY 8
2.2.2 TRANSMISSION 9
2.2.3 PATHOGENESIS 10
2.2.4 CLINICAL SIGNS 10
2.2.5 PATHOLOGY AND HISTOPATHOLOGY 11
2.2.6 IMMUNE RESPONSE 12
2.2.7 EPIDEMIOLOGY 13
2.2.8 PRESENT SITUATION O F OCCURRENCE 15
2.2.8.1 GLANDERS IN PAKISTAN 16
2.2.8.2 GLANDERS IN BRAZIL 17
2.2.8.3 GLANDERS IN GERMANY 18
2.2.9 IMPORTANCE O F GLANDERS AS A DISEASE NOTIFIABLE TO OIE 18
2.2.10 ECONOMIC IMPORTANCE O F EQUIDS 18
2.3 LABORATORY DIAGNOSIS O F GLANDERS 19
2.3.1 B. MALLEI ISOLATION 19
2.3.2 ANTIGEN, PROTEIN AND POLYSACCHARIDE DETECTION 19
2.3.3 SEROLOGICAL DIAGNOSIS 20
2.3.4 DELAYED HYPERSENSITIVITY TESTING (MALLEIN TEST) 24
ILL
HTTP://D-NB.INFO/1025015959
IMAGE 2
2.3.5 MOLECULAR DIAGNOSIS
24
2.3.5.1 CONVENTIONAL P C R AND REAL-TIME P C R METHODS 25
2.3.5.2 PULSE FIELD GEL ELECTROPHORESIS (PFGE) 26
2.3.5.3 MULTILOCUS SEQUENCE TYPING (MLST) 2 7
2.3.5.4 VARIABLE NUMBER TANDEM REPEAT TYPING (VNTR) 2 7
3 MATERIALS AND METHODS 2 8
3.1 MATERIALS 28
3.1.1 SERA COLLECTION 28
3.1.1.1 MATERIALS USED FOR BLOOD SAMPLING AND SERA PREPARATION FROM
PAKISTANI EQUIDS
28
3.1.1.2 STUDY AREA IN PAKISTAN 29
3.1.1.3 SERA SEPARATION AND LABELLING O F SAMPLES 30
3.1.1.4 SERA COLLECTION FROM PAKISTAN 33
3.1.1.5 PACKAGING AND SHIPMENT 33
3.1.1.6 SERA COLLECTION FROM BRAZIL 34
3.1.1.7 SERA COLLECTION FROM GERMANY 34
3.1.1.8 SERA COLLECTION FROM IMMUNISED RABBITS AND HORSES 34
3.1.1.9 ANIMAL ETHICAL ISSUES 35
3.1.1.10 EXPERIMENTAL DESIGNS 35
3.1.1.10.A A PRELIMINARY PREVALENCE STUDY FOR SIX DISTRICTS O F THE
PUNJAB,
PAKISTAN
35
3.1.1.10.B VALIDATION O F CFT ANTIGENS O F THE COMPANIES CCPRO AND CIDC
FOR USE IN AN SOUTH EAST ASIAN ENDEMIC COUNTRY, PAKISTAN
36
3.1.1.10.C VALIDATION O F CFT ANTIGENS USING POSITIVE SERA FROM ASIA AND
SOUTH AMERICA
37
3.1.2 DIAGNOSTIC ANTIGENS 38
3.1.3 COMPLEMENT FIXATION TEST (CFT) 38
3.1.3.1 NEGATIVE AND POSITIVE CONTROL SERA 38
3.1.3.2 CFT- ANALYSIS 39
IV
IMAGE 3
3.1.3.3 REAGENTS, BUFFERS AND EQUIPMENT USED FOR C F T
4 0
3.1.4 WB-ANALYSIS 41
3.2 METHODS 4 3
3.2.1 CFT PRINCIPLE 4 3
3.2.1.1 CFT PROCEDURE 4 4
3.2.2 WB ASSAY PRINCIPLE 45
3.2.2.1 ANTIGEN PREPARATION FOR THE WB ASSAY 4 5
3.2.2.2 IMMUNOBLOTTING (IB) 4 6
3.2.3 STATISTICAL ANALYSIS 4 6
4. RESULTS 49
4.A O N THE CURRENT SITUATION O F GLANDERS IN VARIOUS DISTRICTS O F THE
PAKISTANI
PUNJAB
49
4.B PERFORMANCE O F COMPLEMENT FIXATION TEST AND CONFIRMATORY IMMUNOBLOT
AS TWO-CASCADE TESTING APPROACH FOR SERODIAGNOSIS O F GLANDERS IN AN
ENDEMIC REGION O F SOUTH EAST ASIA
51
4.C COMPARATIVE EVALUATION O F THREE COMMERCIALLY AVAILABLE COMPLEMENT
FIXATION TEST ANTIGENS FOR THE DIAGNOSIS O F GLANDERS
53
5. DISCUSSION AND CONCLUSIONS 56
5.A SEROPREVALENCE O F GLANDERS IN PAKISTANI PUNJAB 56
5.B & C COMPARATIVE EVALUATION O F TWO AND THREE CFT ANTIGENS 59
6. SUMMARY 64
7. ZUSAMMENFASSUNG 66
8. REFERENCES 68
9. LIST O F PUBLICATIONS 86
10. ACKNOWLEDGEMENTS 88
11. SELBSTSTANDIGKEITSERKLARUNG 91
V
|
any_adam_object | 1 |
author | Khan, Iahtasham |
author_facet | Khan, Iahtasham |
author_role | aut |
author_sort | Khan, Iahtasham |
author_variant | i k ik |
building | Verbundindex |
bvnumber | BV040332991 |
collection | ebook |
ctrlnum | (OCoLC)824663823 (DE-599)BVBBV040332991 |
dewey-full | 630 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 630 - Agriculture and related technologies |
dewey-raw | 630 |
dewey-search | 630 |
dewey-sort | 3630 |
dewey-tens | 630 - Agriculture and related technologies |
discipline | Agrar-/Forst-/Ernährungs-/Haushaltswissenschaft / Gartenbau |
format | Thesis Book |
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spelling | Khan, Iahtasham Verfasser aut Serodiagnosis of glanders with reference to endemic and non-endemic settings vorgelegt von Iahtasham Khan Serologische Diagnostik von Rotz unter Berücksichtigung endemischer und nicht-endemischer Tierseuchensituationen Berlin Mensch-und-Buch-Verl. 2012 X, 92 S. Ill., Kt. txt rdacontent n rdamedia nc rdacarrier Nebentitel: Serologische Diagnostik von Rotz unter Berücksichtigung endemischer und nicht-endemischer Tierseuchensituationen Berlin, Freie Univ., Diss., 2012 emerging infectious diseases cabt glanders cabt horses cabt diagnosis cabt zoonoses cabt serology cabt epidemiology cabt Pakistan cabt Brazil cabt Germany cabt Pferd Rotz (DE-588)4578160-6 gnd rswk-swf Serodiagnostik (DE-588)4181044-2 gnd rswk-swf Brasilien Deutschland (DE-588)4113937-9 Hochschulschrift gnd-content Rotz (DE-588)4578160-6 s Serodiagnostik (DE-588)4181044-2 s DE-604 Erscheint auch als Online-Ausgabe urn:nbn:de:kobv:188-fudissthesis000000038528-2 http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000038528 kostenfrei Volltext DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025187384&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Khan, Iahtasham Serodiagnosis of glanders with reference to endemic and non-endemic settings emerging infectious diseases cabt glanders cabt horses cabt diagnosis cabt zoonoses cabt serology cabt epidemiology cabt Pakistan cabt Brazil cabt Germany cabt Pferd Rotz (DE-588)4578160-6 gnd Serodiagnostik (DE-588)4181044-2 gnd |
subject_GND | (DE-588)4578160-6 (DE-588)4181044-2 (DE-588)4113937-9 |
title | Serodiagnosis of glanders with reference to endemic and non-endemic settings |
title_alt | Serologische Diagnostik von Rotz unter Berücksichtigung endemischer und nicht-endemischer Tierseuchensituationen |
title_auth | Serodiagnosis of glanders with reference to endemic and non-endemic settings |
title_exact_search | Serodiagnosis of glanders with reference to endemic and non-endemic settings |
title_full | Serodiagnosis of glanders with reference to endemic and non-endemic settings vorgelegt von Iahtasham Khan |
title_fullStr | Serodiagnosis of glanders with reference to endemic and non-endemic settings vorgelegt von Iahtasham Khan |
title_full_unstemmed | Serodiagnosis of glanders with reference to endemic and non-endemic settings vorgelegt von Iahtasham Khan |
title_short | Serodiagnosis of glanders with reference to endemic and non-endemic settings |
title_sort | serodiagnosis of glanders with reference to endemic and non endemic settings |
topic | emerging infectious diseases cabt glanders cabt horses cabt diagnosis cabt zoonoses cabt serology cabt epidemiology cabt Pakistan cabt Brazil cabt Germany cabt Pferd Rotz (DE-588)4578160-6 gnd Serodiagnostik (DE-588)4181044-2 gnd |
topic_facet | emerging infectious diseases glanders horses diagnosis zoonoses serology epidemiology Pakistan Brazil Germany Pferd Rotz Serodiagnostik Brasilien Deutschland Hochschulschrift |
url | http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000038528 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025187384&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT khaniahtasham serodiagnosisofglanderswithreferencetoendemicandnonendemicsettings AT khaniahtasham serologischediagnostikvonrotzunterberucksichtigungendemischerundnichtendemischertierseuchensituationen |