Epigenomics: from chromatin biology to therapeutics
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Cambridge [u.a.]
Cambridge Univ. Press
2012
|
| Ausgabe: | 1. publ. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XXX, 518 S. Ill., graph. Darst. |
| ISBN: | 9781107003828 |
Internformat
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| 245 | 1 | 0 | |a Epigenomics |b from chromatin biology to therapeutics |c edited by Krishnarao Appasani |
| 250 | |a 1. publ. | ||
| 264 | 1 | |a Cambridge [u.a.] |b Cambridge Univ. Press |c 2012 | |
| 300 | |a XXX, 518 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Epigenetics | |
| 650 | 4 | |a Gene expression | |
| 650 | 0 | 7 | |a Genexpression |0 (DE-588)4020136-3 |2 gnd |9 rswk-swf |
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| 700 | 1 | |a Appasani, Krishnarao |e Sonstige |4 oth | |
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Datensatz im Suchindex
| _version_ | 1804149343473631232 |
|---|---|
| adam_text | Contents
List of contributors page
χ
Foreword by Azim
Surani
xxv
Preface
xxvii
I Basics of chromatin biology and biochemistry
1
1
Introduction to epigenomics
Krishnarao Appasani and Raghu K. Appasani
3
2
Epigenetics and its historical perspectives
Robin Holliday
19
3
Functional networks of human epigenetic factors
Andrey Poleshko,
Natalia Shalginskikh, and Richard A. Katz
30
4
Nucleosome positioning in promoters: significance and open questions
Jun
S.
Song and David E. Fisher
47
5
Chemical reporters of protein methylation and acetylation
Markus Grammel, Yu-Ying Yang, and Howard
С.
Hang 60
6
Long non-coding
RNA
in epigenetic gene silencing
Takashi Nagano
73
II Epigenomic imprinting and stem cells
89
7
Active
DNA demethylation:
the enigma starts in the
zygote
Julia Arand,
Konstantin
Lepikhov, Mark Wossidlo, and
Jörn
Walter
91
8
Histone modifications of lineage-specific genes in human embryonic
stem cells during in vitro differentiation
Hyemin Kim, Hogyu
Seo,
Daeyoup Lee, and Yong-Mahn Han
104
9
Epigenetic stability of human pluripotent stem cells
Céline
Vallót
and Claire Rougeulle
118
10
Impact of CpG methylation in addressing adipose-derived stem cell
differentiation towards the cardiac phenotype
Alice
Pasini, Francesca Bonafè,
Emanuela
Fiumana,
Carlo Guarnieri, Paolo
G.
Morselli,
Carlo M. Oranges,
Claudio
M. Caldarera, Claudio Muscari,
and
Emanuele
Giordano
134
vii
viii Contents
11 Regulation
of the stem cell epigenome by REST
Angela
Bithell
and Noel J. Buckley
146
12
MicroRNAs in embryonic stem cells
Shari Orlanski and Yehudit Bergman
163
13
Regulation of timing of replication
Rituparna Mukhopadhyay and Eric E. Bouhassira
179
III Epigenomic assays and sequencing technology
195
14
Detection of CpG methylation patterns by affinity capture methods
Luis G. Acevedo, Ana Sanz, Dylan Maixner,
Kornel Schuebel,
Mary
A. Jelinek,
David Goldman, and Joseph M. Fernandez
197
15
Genome-wide ChlP-DSL profiling of promoter methylation patterns
associated with cancer and stem cell differentiation
Jeffrey D.
Falk
210
16
Quantitative, high-resolution CpG methylation assays on the
pyrosequencing platform
Dirk
Löffert, Ralf Peist, Thea
Rütjes, Norbert Hochstein,
Dorothée Honsel,
Frank Narz, Ioanna
Andreou,
Richard
Kroon,
Andreas
Missel,
Andrea
Linnemann-Florl,
Lennart
Suckau, and Gerald Schock 223
17 DNA methylation
profiling using
Illumina BeadArray
platform
Marina
Bibikova,
Jian-Bing
Fan, and Kevin L. Gunderson
235
18
Advances in capillary electrophoresis-based methods for
DNA
methylation analysis
Benjamin G. Schroeder, Victoria L. Boyd, and Gerald
Zon
249
19
Genome-wide methylome analysis based on new high-throughput
sequencing technology
Mingzhi Ye,
Fei
Gao,
Xu
Han, Guanyu
Ji,
Zhixiang
Yan, and Honglong Wu
260
20
Three-dimensional quantitative
DNA methylation
imaging for
chromatin
texture analysis in pharmacoepigenomics and
toxicoepigenomics
Jian Tajbakhsh
and
Arkadiusz Gertych
273
IV Epigenomics in disease biology
291
21
Cancer classification by genome-wide and quantitative
DNA
methylation analyses
Atsushi Kaneda
293
22
Promoter CpG island methylation in colorectal cancer: biology and
clinical applications
Sarah Derks and
Manon
van
Engeland
306
23
The epigenetic profile of bladder cancer
Ewa Dudziec
and James
W. F.
Catto
323
24
Genome-scale
DNA
methylation analyses of cancer in children
Nicholas C. Wong and David M. Ashley
338
25
The epigenetics of facioscapulohumeral muscular dystrophy
Weihua
Zeng,
Alexander R. Ball, Jr., and Kyoko Yokomori
347
26
Modulating histone acetylation with inhibitors and activators
B. Ruthrotha Selvi, D. V. Mohankrishna, and
Tapas
К.
Kundu
362
Contents ix
V
Epigenomics in
neurodegenerative
diseases
389
27
Study design considerations in epigenetic studies of
neuropsychiatrie
disease
Fatemeh Haghighi, Sephorah Zaman, and Yurong Xin
391
28
Epigenetic regulation in human neurodevelopmental disorders
including autism,
Rett
syndrome, and epilepsy
Laura
B. K.
Herzing
404
29
The neurobiology of chromatin-associated mechanisms in the context
of psychosis and mood spectrum disorders
Schahram Akbarian 420
30
Genome-wide
DNA methylation
analysis in patients with familial
ATR-X mental retardation syndrome
Gemma Carvill and Andrew Sharp
434
31
Kinases and phosphatases in the epigenetic regulation of cognitive
functions
Tamara
В.
Franklin and
Isabelle M. Mansuy
447
VI Epigenetic variation, polymorphism, and epidemiological perspectives
459
32
Epigenetic effects of childhood abuse on the human brain
Benoit Labonté
and Gustavo
Turecki
461
33
Х
-linked expressed single nucleotide polymorphisms and dosage
compensation
Lygia V.
Pereira
and
Joana
С.
Moreira
de Mello
483
34
Epigenomic diversity of colorectal cancer
Aditi
Hazra and Shuji Ogino
491
35
Epigenetic epidemiology: transgenerational responses to the
environment
Lars
Olov Bygren
505
Index
514
The colour plates are to be found between pages
162
and
163
Advance praise for Epigenomics
...
a very impressive collection of high-quality contributions... it will be a very useful
resource for everyone in the epigenetics field. I will definitely recommend it to my
colleagues!
Karl
Ekwall,
Professor of Medical Genetics and Epigenetics.
Karolinska
Institute, Stockholm.
Sweden
...
an excellent work, highly readable and well documented by more than a hundred
scientists from
academia
and industry. The extensive coverage of current theory, new
technologies, and disease mechanisms, all associated with epigenomics, makes
this book invaluable to students and researchers in a wide range of disciplines.
Recommended for all academic libraries.
Atsuo Ogura, Head of Bioresource i_,
,
Japan
...
an excellent update on the current status of epigenomics, a relatively new discipline of
life sciences bridging genetics and epigenetics. Experts in their field provide up-to-date
information making the book very valuable for
academia
and biotech working in the field
of diagnostics and therapeutics.
Christine Guenther, CEOofapceth GmbH
&
Co. KG. Munich, Germany
I recommend this book
asan
excellent up-to-date reference for established
investigators in the field of epigenomics and to newcomers who want an update of
the recent developments in this field. The book can also serve as a reference text for
students as part of an advanced course on molecular biology.
Richard L. Momparler, Professor of Pharmacology.
University of Montreal. Canada
Appasani gathers our present knowledge about epigenomics.
..
the topics covered will allow the reader to understand the
role of epigenetic mechanisms in cell biology and disease.
At the same time, this book offers a good
opportunity to learn about the epigenomic
techniques applied in both basic research
and in biotechnology.
Marian Martinez-Balbas,
Senior Research Scientist.
CSIC-Barcelona Molecular Biology Institute. Spain
sed
in nanotechnoioc
.
Cover designed by Hart McLeod Ltd
UNIVERSITY PRESS
www.cambridge.org
IISBN
978-1-107-00382-8
|
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| spelling | Epigenomics from chromatin biology to therapeutics edited by Krishnarao Appasani 1. publ. Cambridge [u.a.] Cambridge Univ. Press 2012 XXX, 518 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index Epigenetics Gene expression Genexpression (DE-588)4020136-3 gnd rswk-swf Epigenetik (DE-588)7566079-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Epigenetik (DE-588)7566079-9 s DE-604 Genexpression (DE-588)4020136-3 s b DE-604 Appasani, Krishnarao Sonstige oth Digitalisierung UB Bayreuth application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025172957&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Bayreuth application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025172957&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Epigenomics from chromatin biology to therapeutics Epigenetics Gene expression Genexpression (DE-588)4020136-3 gnd Epigenetik (DE-588)7566079-9 gnd |
| subject_GND | (DE-588)4020136-3 (DE-588)7566079-9 (DE-588)4143413-4 |
| title | Epigenomics from chromatin biology to therapeutics |
| title_auth | Epigenomics from chromatin biology to therapeutics |
| title_exact_search | Epigenomics from chromatin biology to therapeutics |
| title_full | Epigenomics from chromatin biology to therapeutics edited by Krishnarao Appasani |
| title_fullStr | Epigenomics from chromatin biology to therapeutics edited by Krishnarao Appasani |
| title_full_unstemmed | Epigenomics from chromatin biology to therapeutics edited by Krishnarao Appasani |
| title_short | Epigenomics |
| title_sort | epigenomics from chromatin biology to therapeutics |
| title_sub | from chromatin biology to therapeutics |
| topic | Epigenetics Gene expression Genexpression (DE-588)4020136-3 gnd Epigenetik (DE-588)7566079-9 gnd |
| topic_facet | Epigenetics Gene expression Genexpression Epigenetik Aufsatzsammlung |
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