Sleep hormones:
Gespeichert in:
1. Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Amsterdam [u.a.]
Elsevier
2012
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Schriftenreihe: | Vitamins and hormones
89 |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | Einzelaufn. für Zeitschr.-H. |
Beschreibung: | XVIII, 370 S. Ill., graph. Darst. |
Internformat
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Datensatz im Suchindex
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adam_text | Titel: Sleep hormones
Autor: Litwack, Gerald
Jahr: 2012
Contents
Contributors xiii
Preface xvii
1. Neurohormones and Sleep 1
Eric Frenette, Alben Lui, and Michelle Cao
I. Introduction 2
II. Pineal Gland 3
III. Adenohypophysis 5
IV. Neurohypophysis Axis 10
V. Other Hormones 11
VI. Summary 12
References 12
2. The Role of Orexin/Hypocretin in the Central Nervous
System and Peripheral Tissues 19
Tomomi Tsunematsu and Akihiro Yamanaka
I. Introduction 20
II. Orexin and Orexin Receptors 21
III. Function of Orexins in Feeding Behavior and Energy Homeostasis 24
IV. Function of Orexins in Peripheral Tissues 26
V. Conclusions and Future Directions 28
Acknowledgments 28
References 29
3. Plasticity in Neurons Synthesizing Wake/Arousal
Promoting Hormone Hypocretin/Orexin 35
Xiao-Bing Gao
I. Introduction 36
II. Assessment of Neural Plasticity in Hypocretin/Orexin Neurons 37
III. The Expression of Experience-Dependent Plasticity in
Hypocretin/Orexin Neurons 40
IV. Factors Modifying the Plasticity in Hypocretin/Orexin Neurons 49
V. Conclusions and Future Directions 51
VII
viii Contents
Acknowledgments 53
References 54
4. Expression of Orexin Receptors in the Pituitary 61
Tadeusz Kaminski and Nina Smolinska
I. Introduction 62
II. Expression of OXiR and OX2R mRNAs and Proteins 62
III. Regulation of Orexin Receptor Expression 65
IV. The Role of the Orexin System in the Pituitary 67
V. Conclusions and Follow-up Research 70
Acknowledgments 70
References 71
5. Transcriptional Regulation of the Hypocretin/Orexin Gene 75
Susumu Tanaka
I. Introduction 76
II. Hypocretin/Orexin Regulatory Elements 76
III. Colocalization with STAT3 in Hypocretin Neurons jy
IV. Interferon-Alpha Regulates Hypocretin-Promoter
Activity In Vitro 77
V. Hypocretin Expression in the Postnatal Period 78
VI. Embryonic Hypocretin Expression 78
VII. FOXA2 Regulates Hypocretin Expression 80
VIII. Is There Diurnal Variation in Hypocretin Expression? 80
IX. IGFBP3 Modulates Hypocretin Expression Levels 81
X. Does Nur77 Affect the Activity of the Preprohypocretin
Promoter? (Tanaka et al., 2009) 81
XI. Transcriptional Regulation of the Hypocretin/Orexin
Gene by NR6A1 83
XII. Transcription Factors Downregulated in Hypocretin/Ataxin-3
Transgenic Mice 84
XIII. Conclusions and Future Directions 85
Acknowledgments 86
References 86
6. Energy Expenditure: Role of Orexin 91
Jennifer A. Teske and Vijayakumar Mavanji
I. Introduction 91
II. Conclusion 101
References 101
Contents ix
7. Orexins: Tissue Localization, Functions, and Its Relation
to Insulin Secretion and Diabetes Mellitus 111
Ernest Adeghate
I. Introduction 112
II. Origin of Orexins 113
III. Structure of Orexins 113
IV. Receptors of Orexins 113
V. Tissue Distribution of Orexins 114
VI. Physiological Effects 123
VII. Mechanism of Orexin Action 124
VIII. Conclusion and Future Perspectives 127
Acknowledgments 127
References 127
8. Orexin Neurons and Emotional Stress 135
Tomoyuki Kuwaki and Wei Zhang
I. Introduction 136
II. Orexin Neurons 138
III. Behavior-Associated Changes in Autonomic Functions 141
IV. Lessons from Orexin-Deficient Mice 143
V. Relevant Data from Normal Rodents and Narcoleptic Humans 150
VI. Conclusions 151
Acknowledgments 152
References 152
9. Orexin and Central Regulation of Cardiorespiratory System 159
Israt Z. Shahid, Ahmed A. Rahman, and Paul M. Pilowsky
I. Introduction 160
II. Orexins and Orexin Receptors 160
III. Connections of Orexins with Other Transmitters 165
IV. Systemic Effects of Orexin 166
V. Central Cardiovascular Effects of Orexin 171
VI. Respiratory Effects of Orexin 173
VII. Conclusion 174
Acknowledgments 175
References 176
10. Hypocretin/Orexin Involvement in Reward and Reinforcement 185
Rodrigo A. Espana
I. Introduction 186
II. Hypocretin Regulation of Reward and Reinforcement Processes 188
X Contents
III. Hypocretin Regulation of Dopamine Signaling 195
IV. Conclusions 202
References 202
11. Glutamate and Orexin Neurons 209
Ozhan Eyigor, Zehra Minbay, and llker M. Kafa
I. Introduction 210
II. Glutamate and Glutamate Receptors in the Lateral Hypothalamus 210
III. Glutamatergic Afférents of Orexin Neurons 212
IV. Effects of Glutamate Agonists and Antagonists on the
Activation of Orexin Neurons 214
V. Glutamate Receptor Expression by Orexin Neurons 215
VI. Conclusion 218
Acknowledgment 219
References 219
12. Serotonin Conflict in Sleep-Feeding 223
Katsunori Nonogaki
I. Introduction 224
II. Brain Areas Involved in the Regulation of Sleep 225
III. The Distribution of the 5-HT Receptors Involved in
Regulation of Sleep and Feeding 225
IV. Role of 5-HT2C Receptors in Sleep-Feeding Behavior 226
V. 5-HT Receptors Other than 5-HT2C Receptors 230
VI. Pharmacologic Studies of 5-HT Receptors Other than
the 5-HT2C Receptor 230
VII. Conclusion 233
Acknowledgments 235
References 235
13. Humoral Sleep Regulation; lnterleukin-i and Tumor
Necrosis Factor 241
Kathryn A. Jewett and James M. Krueger
I. Introduction 242
II. Interleukin-iß and Tumor Necrosis Factor a 242
III. Cytokine Production and Release 245
IV. Cytokines and Sleep 245
V. Cytokines in Sleep Regulation 247
Acknowledgment 249
References 249
Contents xi
14. Action of Modafinil Through Histaminergic
and Orexinergic Neurons 259
Tomoko Ishizuka, Tomotaka Murotani, and Atsushi Yamatodani
I. Introduction 260
II. Neuronal Targets of Modafinil 260
III. The Interplay Between the Histaminergic and the
Orexinergic Systems 264
IV. The Effects of Modafinil on the Histaminergic and the
Orexinergic Systems 266
V. Modafinil and Orexin—What Is the Physiological Role? 270
VI. Conclusion and Perspectives 272
References 273
15. Anti-Parkinson Drugs and Orexin Neurons 279
Hiroshi Katsuki and Shotaro Michinaga
I. Introduction 280
II. Parkinson Disease and Adverse Actions of Anti-Parkinson Drugs 280
III. Properties of Orexin Neurons 281
IV. Possible Dysfunctions of Orexin Neurons Associated with
Parkinson Disease 284
V. Conclusions and Perspectives 288
Acknowledgments 289
References 289
16. Cocaine and Nicotine Research Illustrates a Range of
Hypocretin Mechanisms in Addiction 291
Corey Baimel, Stephanie L Borgland, and William Corrigall
I. Addiction and the Mesolimbic Dopamine System 292
II. Hypocretin Involvement with the Mesolimbic Dopamine System 292
III. Hypocretin-i Effects on NMDAR Currents in Dopamine Neurons 293
IV. Hypocretin-i Effects on AMPAR EPSCs in Dopamine Neurons 294
V. Hypocretin-2 and Plasticity of Dopamine Neurons 294
VI. Hypocretin and Drug-Induced Synaptic Plasticity 295
VII. Hypocretin and Behavioral Plasticity 296
VIII. Hypocretin and the Motivation for Drugs 297
IX. Existing Studies of Hypocretin Mechanisms in the
Effects of Nicotine 298
X. Rationale for Further Study of Hcrt Mechanisms in the
Preclinical Effects of Nicotine 302
XI. Questions for a Preclinical Discovery Research Agenda 303
References 307
xii Contents
17. Sleep and Orexins in Nonmammalian Vertebrates 315
Hélène Volkoff
I. Introduction 316
II. Orexins 317
III. Sleep and OXs in Birds 319
IV. Sleep and OXs in Reptiles 321
V. Sleep and OXs in Amphibians 323
VI. Sleep and OXs in Fish 324
VII. Conclusions and Future Directions 328
Acknowledgment 331
References 331
18. Orexin System in Teleost Fish 341
Kouhei Matsuda, Morio Azuma, and Ki Sung Kang
I. Introduction 342
II. Orexin and Its Receptor in Teleost Fish 343
III. Distribution of Orexin Precursor Transcript and Orexin-Like
Immunoreactivity in Teleost Fish 346
IV. Effect of Orexin on Food Intake in Teleost Fish 347
V. Effect of Orexin on Locomotor and Psychomotor Activities
and the Sleep/Wakefulness Cycle in Teleost Fish 353
VI. Conclusions 356
Acknowledgments 357
References 357
Index 363
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spelling | Litwack, Gerald Verfasser aut Sleep hormones ed.-in-chief: Gerald Litwack Amsterdam [u.a.] Elsevier 2012 XVIII, 370 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Vitamins and hormones 89 Einzelaufn. für Zeitschr.-H. HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025105826&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Litwack, Gerald Sleep hormones |
title | Sleep hormones |
title_auth | Sleep hormones |
title_exact_search | Sleep hormones |
title_full | Sleep hormones ed.-in-chief: Gerald Litwack |
title_fullStr | Sleep hormones ed.-in-chief: Gerald Litwack |
title_full_unstemmed | Sleep hormones ed.-in-chief: Gerald Litwack |
title_short | Sleep hormones |
title_sort | sleep hormones |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025105826&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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