Endothelin in renal physiology and disease:
Endothelin is a 21-amino acid peptide that exerts uniquely potent and long-lasting effects on the kidney, including regulation of water and electrolyte excretion, blood pressure, cell growth, inflammation and fibrosis. During the past 10 years, the field has evolved rapidly; we are now uncovering th...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Basel
Karger
2011
|
| Schriftenreihe: | Contributions to nephrology
Vol. 172 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | Endothelin is a 21-amino acid peptide that exerts uniquely potent and long-lasting effects on the kidney, including regulation of water and electrolyte excretion, blood pressure, cell growth, inflammation and fibrosis. During the past 10 years, the field has evolved rapidly; we are now uncovering the potential importance of endothelin receptor antagonists (ERAs) in the treatment of kidney disease.This book reviews experimental concepts, preclinical studies and clinical data which form the basis of our current understanding of the association between endothelin and kidney disease. Acclaimed experts in pharmacology, molecular biology, physiology, cardiovascular medicine, and nephrology have contributed timely reviews dealing with renal pharmacology and physiology of endothelin, the role of endothelin in renal disease development and ERAs in preclinical studies, and the current state of clinical development of ERA therapy in renal medicine.The publication at hand will be a valuable reference source for nephrologists, internists and other healthcare professionals, renal physiologists and molecular biologists, post-doctoral researchers and students in the life sciences, as well as for scientists and decision makers in drug research and development |
| Beschreibung: | A comprehensive reference book on basic and clinical aspects |
| Beschreibung: | 1 Online-Ressource (VIII, 266 Seiten) Illustrationen |
| ISBN: | 9783805597951 |
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Datensatz im Suchindex
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|---|---|
| adam_text | |
| any_adam_object | |
| author2 | Barton, Matthias Kohan, Donald E. |
| author2_role | edt edt |
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| author_GND | (DE-588)1089455704 |
| author_facet | Barton, Matthias Kohan, Donald E. |
| building | Verbundindex |
| bvnumber | BV040231366 |
| classification_rvk | XG 8050 YK 7989 |
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| dewey-full | 616.6106 612.463 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases 612 - Human physiology |
| dewey-raw | 616.6106 612.463 |
| dewey-search | 616.6106 612.463 |
| dewey-sort | 3616.6106 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Electronic eBook |
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| indexdate | 2025-03-05T11:01:18Z |
| institution | BVB |
| isbn | 9783805597951 |
| language | English |
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| spelling | Endothelin in renal physiology and disease volume editors: Matthias Barton, Donald E. Kohan Basel Karger 2011 1 Online-Ressource (VIII, 266 Seiten) Illustrationen txt rdacontent c rdamedia cr rdacarrier Contributions to nephrology Vol. 172 A comprehensive reference book on basic and clinical aspects Endothelin is a 21-amino acid peptide that exerts uniquely potent and long-lasting effects on the kidney, including regulation of water and electrolyte excretion, blood pressure, cell growth, inflammation and fibrosis. During the past 10 years, the field has evolved rapidly; we are now uncovering the potential importance of endothelin receptor antagonists (ERAs) in the treatment of kidney disease.This book reviews experimental concepts, preclinical studies and clinical data which form the basis of our current understanding of the association between endothelin and kidney disease. Acclaimed experts in pharmacology, molecular biology, physiology, cardiovascular medicine, and nephrology have contributed timely reviews dealing with renal pharmacology and physiology of endothelin, the role of endothelin in renal disease development and ERAs in preclinical studies, and the current state of clinical development of ERA therapy in renal medicine.The publication at hand will be a valuable reference source for nephrologists, internists and other healthcare professionals, renal physiologists and molecular biologists, post-doctoral researchers and students in the life sciences, as well as for scientists and decision makers in drug research and development Nierenkrankheit (DE-588)4075399-2 gnd rswk-swf Endothelin (DE-588)4255702-1 gnd rswk-swf Pharmakologischer Antagonist (DE-588)4198682-9 gnd rswk-swf Niere (DE-588)4042270-7 gnd rswk-swf Rezeptor (DE-588)4049722-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Niere (DE-588)4042270-7 s Nierenkrankheit (DE-588)4075399-2 s Endothelin (DE-588)4255702-1 s Rezeptor (DE-588)4049722-7 s Pharmakologischer Antagonist (DE-588)4198682-9 s DE-604 Barton, Matthias (DE-588)1089455704 edt Kohan, Donald E. edt Erscheint auch als Druck-Ausgabe 978-3-8055-9794-4 (DE-604)BV039606480 Contributions to nephrology Vol. 172 (DE-604)BV039142755 172 https://karger.com/books/book/2746 Verlag Volltext |
| spellingShingle | Endothelin in renal physiology and disease Contributions to nephrology Nierenkrankheit (DE-588)4075399-2 gnd Endothelin (DE-588)4255702-1 gnd Pharmakologischer Antagonist (DE-588)4198682-9 gnd Niere (DE-588)4042270-7 gnd Rezeptor (DE-588)4049722-7 gnd |
| subject_GND | (DE-588)4075399-2 (DE-588)4255702-1 (DE-588)4198682-9 (DE-588)4042270-7 (DE-588)4049722-7 (DE-588)4143413-4 |
| title | Endothelin in renal physiology and disease |
| title_auth | Endothelin in renal physiology and disease |
| title_exact_search | Endothelin in renal physiology and disease |
| title_full | Endothelin in renal physiology and disease volume editors: Matthias Barton, Donald E. Kohan |
| title_fullStr | Endothelin in renal physiology and disease volume editors: Matthias Barton, Donald E. Kohan |
| title_full_unstemmed | Endothelin in renal physiology and disease volume editors: Matthias Barton, Donald E. Kohan |
| title_short | Endothelin in renal physiology and disease |
| title_sort | endothelin in renal physiology and disease |
| topic | Nierenkrankheit (DE-588)4075399-2 gnd Endothelin (DE-588)4255702-1 gnd Pharmakologischer Antagonist (DE-588)4198682-9 gnd Niere (DE-588)4042270-7 gnd Rezeptor (DE-588)4049722-7 gnd |
| topic_facet | Nierenkrankheit Endothelin Pharmakologischer Antagonist Niere Rezeptor Aufsatzsammlung |
| url | https://karger.com/books/book/2746 |
| volume_link | (DE-604)BV039142755 |
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