Cytoskeleton and human disease:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY [u.a.]
Humana Press, Springer
2012
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | XXIV, 453 S. Ill., graph. Darst. |
| ISBN: | 9781617797873 |
Internformat
MARC
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| 245 | 1 | 0 | |a Cytoskeleton and human disease |c Maria Kavallaris, ed. |
| 264 | 1 | |a New York, NY [u.a.] |b Humana Press, Springer |c 2012 | |
| 300 | |a XXIV, 453 S. |b Ill., graph. Darst. | ||
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Datensatz im Suchindex
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|---|---|
| adam_text |
Contents
Part I Basics of the Cytoskeleton
1
ACTIN
. 3
Vera
Dugina,
Richard
Arnoldi,
Paul A. Janmey and Christine Chaponnier
2
Microtubules
. 29
Pavel Draber and
Eduarda Dráberová
3
The Kinesin Superfamily
. 55
Linda
Wordeman
4
Basics of the Cytoskeleton: Myosins
. 73
Omar
A. Quintero,
Judy E. Moore and Christopher M. Yengo
Part II Actin and Disease
5
The Actin Cytoskeleton and Membrane Organisation
in
Τ
Lymphocytes
. 103
Rhea Comely, Thomas Grewal and
Katharina Gaus
6
Thin Filament Diseases of Striated Muscle
. 123
Anthony J. Kee and Edna C. Hardeman
7
Filamins
and Disease
. 141
Stephen P. Robertson and Philip B. Daniel
8
LIM
Kinase and Cancer Metastasis
. 159
Alice Schofield and
Ora
Bernard
9
Actin Mutations and Deafness
. 169
Matías Morín,
Fernando Mayo, Felipe Moreno and
Miguel A. Moreno-Pelayo
xii
Contents
10
Therapeutic Targeting of the Actin Cytoskeleton in Cancer
. 181
Teresa Bonello, Jason Coombes,
Galina Schevzov,
Peter Gunning and Justine Stehn
Part III Microtubules and Disease
11
Microtubules as a Target in Cancer Therapy
. 203
April L. Risinger and Susan L. Mooberry
12
Microtubules, Drug Resistance, and Tumorigenesis
. 223
Joshua A. McCarroll and Maria Kavallaris
13
Posttranslational Modifications of Tubulin
. 241
Suzan
К.
Chao,
Chia-Ping
H.
Yang and Susan Band Horwitz
14 Stathmin
and Cancer
. 259
Dominic Chi Hiung Ng and Frances
Byrne
15
The Biology and Pathobiology of
Tau Protein. 285
Garth
F. Hall
16 Tubulin-
Related Malformations of Cortical
Development. 315
Xavier H.
Jaglin, Jamel Chelly and
Nadia Bahi-Buisson
Part
IV Intermediate Filaments and Disease
17
Spectrins in Human Diseases
. 345
Marie-Christine Lecomte
18
Laminopathies
. 375
Nadir M. Maraldi and
Giovanna Lattanzi
19
Desmin and Heart Disease
. 411
J. Scott Pattison and Jeffrey Robbins
20
Neurodegenerative
Diseases and Intermediate Filaments
. 425
Rodolphe
Perrot
and Jean-Pierre
Julien
Index
. 449
Maria Kavallaris
Editor
Cytoskeleton
and Human Disease
The cytoskeleton
is made up of a large variety of specialized proteins and is a highly
dynamic system that is involved in the majority of key cellular events. It is now clear that
the cytoskeleton is often associated, and has diverse roles in human disease. Emerging
understanding of the molecular and cellular events that drive cytoskeletal mediated
disease including cancer, heart disease,
myopathies,
neurodegenerative
diseases and skin
disorders, are also helping shape targeted therapeutic approaches to treat these diseases.
Cytoskeleton and Human Disease Book Summary reviews the key components, mecha¬
nisms and clinical implications of cytoskeletal defects in disease. Contributed by lead¬
ing investigators in their respective fields, the chapters include topics associated with
the basics of the cytoskeleton, actin-associated disease states, microtubule-associated
disease states and intermediate filament-associated disease states.
This authoritative volume is intended for a wide audience of clinicians, researchers and
students with an interest in the application of
biomedical
research to the understanding
and management of disease states associated with the cytoskeleton. |
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| indexdate | 2024-08-14T00:53:20Z |
| institution | BVB |
| isbn | 9781617797873 |
| language | English |
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| physical | XXIV, 453 S. Ill., graph. Darst. |
| publishDate | 2012 |
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| publisher | Humana Press, Springer |
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| spelling | Cytoskeleton and human disease Maria Kavallaris, ed. New York, NY [u.a.] Humana Press, Springer 2012 XXIV, 453 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Zellskelett (DE-588)4121944-2 gnd rswk-swf Krankheit (DE-588)4032844-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Zellskelett (DE-588)4121944-2 s Krankheit (DE-588)4032844-2 s DE-604 Kavallaris, Maria Sonstige oth Erscheint auch als Online-Ausgabe 978-1-61779-788-0 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025001475&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=025001475&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Cytoskeleton and human disease Zellskelett (DE-588)4121944-2 gnd Krankheit (DE-588)4032844-2 gnd |
| subject_GND | (DE-588)4121944-2 (DE-588)4032844-2 (DE-588)4143413-4 |
| title | Cytoskeleton and human disease |
| title_auth | Cytoskeleton and human disease |
| title_exact_search | Cytoskeleton and human disease |
| title_full | Cytoskeleton and human disease Maria Kavallaris, ed. |
| title_fullStr | Cytoskeleton and human disease Maria Kavallaris, ed. |
| title_full_unstemmed | Cytoskeleton and human disease Maria Kavallaris, ed. |
| title_short | Cytoskeleton and human disease |
| title_sort | cytoskeleton and human disease |
| topic | Zellskelett (DE-588)4121944-2 gnd Krankheit (DE-588)4032844-2 gnd |
| topic_facet | Zellskelett Krankheit Aufsatzsammlung |
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