Tumour-associated macrophages:
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
New York, NY [u.a.]
Springer Science+Business Media, LLC
2012
|
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis Klappentext |
Beschreibung: | XI, 187 S. Ill., graph. Darst. |
ISBN: | 9781461406617 |
Internformat
MARC
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300 | |a XI, 187 S. |b Ill., graph. Darst. | ||
336 | |b txt |2 rdacontent | ||
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Datensatz im Suchindex
_version_ | 1804149079659249664 |
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adam_text | Contents
Part I Form and Function
1
Macrophage Phenotype
in Tumours
.....................................................
я
Hsi-Hsien I.in and Siamon Gordon
2
Role of Tumour-Associated
Macrophages
in the Regulation
of Angiogenesis
........................................................................................ 17
Russell Hughes. Hsin-Yu Pang.
Muniţia Muthana.
and Claire E. Lewis
3
The Role of Tumour-Associated
Macrophages
in Malignant Invasion
............................................................................. 31
Claudia Binder
4
Tumour-Induced Immune Suppression by Myeloid Cells
................... 49
Serena Zilio.
Giacomo
Desantis, Mariacristina
Chioda,
and
Vincenzo
Bronte
5
ТАМ:
A Moving Clinical Target
............................................................ 63
Simon
Hallam
and
Thorsten Hagemann
Part II Mechanisms of Action
6
Arginine
Metabolism and Tumour-Associated
Macrophages
............. 77
Melissa Phillips and Peter W. Szlosarek
7
Indoleamine 2J-Diox>
genäse
Amino
Acid Metabolism
and Tumour-Associated
Macrophages:
Regulation
in Cancer-Associated Inflammation and Immune Escape
.................. 91
George C. Prendergast. Richard
Metz.
Mee
Young Chang.
Courtney Smith. Alexander J.
Muller,
and Suzanne Ostrand-Rosenberg
viii Contents
8
Vascular Endothelial
Growth
Factor and
Tumour-Associated
Macrophages
............................................................................................ 105
Christian
Stockmann
and Randall
S.
Johnson
Part III Molecular Regulation
9
TLR Signaling and Tumour-Associated
Macrophages
........................ 119
Oscar R.
Colegio
and Ruslan Medzhitov
10
SHIP and Tumour-Associated
Macrophages
....................................... 135
Victor W. Ho,
Melisa
J.
Hamilton, Etsushi Kuroda, Jens Ruschmann,
Frann Antignano, Vivian Lam, and Gerald
Krystal
11
NF-KappaB-Mediated Regulation of Tumour-Associated
Macrophages:
Mechanisms and Significance
....................................... 153
Antonio
Sica
and Alberto
Mantovani
12
Role of Hypoxia-Inducible Transcription Factors
in
ТАМ
Function
..................................................................................... 167
Nadine Rohwer
and
Thorsten
Cramer
Index
................................................................................................................. 183
lob? Lawrence-
Thersten
Надашяп
Шт
Tumour-AssťKiiated
Macrophages
Macrophages are tissu«
resident
phagocytes
that have important roles in development
and immunity. The observation that cancers become infiltrated by large numbers of
macrophages
was first made by Virchow in
1863,
dinical and
experimentai
studies
suggest tumor-associated
macrophages
(ТАМ)
are critical to promote carcinogenesis and
tumor-progression, however to this day it still isn t clear what regulates the recruitment
of
macrophages
in tumors and what drives their pro-tumor functions. This volume wffl
provide an overview of current research on the form and function of
ТАМ,
highlightiag
both the mechanistic roles they play in carcinogenesis and tumor progression as well
as the molecular mechanisms that control their phenotype and function, and the final
chapter addresses the issue of
ТАМ
as a potential target in cancer therapy.
|
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genre_facet | Aufsatzsammlung |
id | DE-604.BV040120361 |
illustrated | Illustrated |
indexdate | 2024-07-10T00:17:20Z |
institution | BVB |
isbn | 9781461406617 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-024976462 |
oclc_num | 773929470 |
open_access_boolean | |
owner | DE-355 DE-BY-UBR |
owner_facet | DE-355 DE-BY-UBR |
physical | XI, 187 S. Ill., graph. Darst. |
publishDate | 2012 |
publishDateSearch | 2012 |
publishDateSort | 2012 |
publisher | Springer Science+Business Media, LLC |
record_format | marc |
spelling | Tumour-associated macrophages Toby Lawrence ; Thorsten Hagemann, ed. New York, NY [u.a.] Springer Science+Business Media, LLC 2012 XI, 187 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Tumorassoziierter Makrophage (DE-588)4294570-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Tumorassoziierter Makrophage (DE-588)4294570-7 s DE-604 Lawrence, Toby Sonstige oth Erscheint auch als Online-Ausgabe 978-1-4614-0662-4 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024976462&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024976462&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
spellingShingle | Tumour-associated macrophages Tumorassoziierter Makrophage (DE-588)4294570-7 gnd |
subject_GND | (DE-588)4294570-7 (DE-588)4143413-4 |
title | Tumour-associated macrophages |
title_auth | Tumour-associated macrophages |
title_exact_search | Tumour-associated macrophages |
title_full | Tumour-associated macrophages Toby Lawrence ; Thorsten Hagemann, ed. |
title_fullStr | Tumour-associated macrophages Toby Lawrence ; Thorsten Hagemann, ed. |
title_full_unstemmed | Tumour-associated macrophages Toby Lawrence ; Thorsten Hagemann, ed. |
title_short | Tumour-associated macrophages |
title_sort | tumour associated macrophages |
topic | Tumorassoziierter Makrophage (DE-588)4294570-7 gnd |
topic_facet | Tumorassoziierter Makrophage Aufsatzsammlung |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024976462&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024976462&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT lawrencetoby tumourassociatedmacrophages |