Clinical neuroanatomy: brain circuitry and its disorders
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2011
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| Beschreibung: | XXIV, 834 S. Ill., graph. Darst. 29 cm |
| ISBN: | 9783642191336 3642191339 |
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| 245 | 1 | 0 | |a Clinical neuroanatomy |b brain circuitry and its disorders |c Hans J. ten Donkelaar. In co-operation with: Jiři Brabec ... |
| 264 | 1 | |a Berlin [u.a.] |b Springer |c 2011 | |
| 300 | |a XXIV, 834 S. |b Ill., graph. Darst. |c 29 cm | ||
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Datensatz im Suchindex
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IMAGE 1
CONTENTS
CHAPTER 1 OVERVIEW OF THE HUMAN BRAIN AND SPINAL CORD HANSJ. TEN
DONKELAAR AND ANTHONY H.M. LOHMAN 1.1 INTRODUCTION 1
1.2 MACROSCOPY OF THE BRAIN 1
1.2.1 LATERAL VIEW OF THE BRAIN 2
1.2.2 MEDIAL VIEW OF THE BRAIN 3
1.2.3 DORSAL VIEW OF THE BRAIN 3
1.2.4 BASAL VIEW OF THE BRAIN AND ITS RELATIONS TO THE SKULL BASE 4
1.2.5 SOME HORIZONTAL SECTIONS OF THE BRAIN 6
1.2.6 IMAGING OF THE BRAIN 6
1.3 THE MENINGES, THE INTRACRANIAL COMPARTMENTS AND THE LIQUOR
CIRCULATION 7
1.3.1 THE MENINGES 7
CLINICAL CASE 1.1 EPIDURAL, SUBDURAL AND SUBARACHNOID HAEMORRHAGES
ANTOINE KEYSER AND PIETER WESSELING 12
1.3.2 THE INTRACRANIAL COMPARTMENTS 13
CLINICAL CASE 1.2 SPACE-OCCUPYING LESIONS ANTOINE KEYSER AND PIETER
WESSELING 13
1.3.3 THE LIQUOR CIRCULATION 15
1.4 THE SPINAL CORD 15
1.4.1 GROSS ANATOMY 16
1.4.2 MICROSCOPY: SUBDIVISION OF GREY AND WHITE MATTER 17
1.5 THE BRAIN STEM 21
1.5.1 THE CRANIAL NERVES 21
1.5.2 THREE CROSS-SECTIONS THROUGH THE BRAIN STEM 23
1.5.3 THE RETICULAR FORMATION AND RELATED MONOAMINERGIC AND CHOLINERGIC
NUCLEI. 26 1.6 THE CEREBELLUM 27
1.6.1 GROSS ANATOMY, SUBDIVISION AND COMPARTMENTALIZATION 28
1.6.2 MAJOR FIBRE CONNECTIONS 29
1.6.3 PRECEREBELLAR NUCLEI 30
1.7 THE DIENCEPHALON 30
1.7.1 SUBDIVISION 30
1.7.2 THE THALAMUS AND THALAMOCORTICAL CONNECTIONS 31
1.7.3 THE HYPOTHALAMUS 35
1.8 THE TELENCEPHALON 36
1.8.1 SUBDIVISION: PALLIUM AND SUBPALLIUM 36
1.8.2 BRODMANN'S AND OTHER CORTICAL MAPS 38
1.8.3 OVERVIEW OF CORTICAL CONNECTIONS 41
1.8.4 THE LIMBIC SYSTEM: RHINENCEPHALON, THE HIPPOCAMPAL FORMATION AND
THE AMYGDALA 46
1.8.5 THE BASAL GANGLIA AND RELATED BASAL FOREBRAIN STRUCTURES 50
REFERENCES 54
BIBLIOGRAFISCHE INFORMATIONEN HTTP://D-NB.INFO/1009499254
DIGITALISIERT DURCH
IMAGE 2
CONTENTS
CHAPTER 2 VASCULARIZATION OF THE BRAIN AND SPINAL CORD HANS J. TEN
DONKELAAR, TON VAN DER VLIET, ANTHONY H.M. LOHMAN,
ANTOINE KEYSER, AND PIETER WESSELING 2.1 INTRODUCTION 61
2.2 A FEW NOTES ON THE DEVELOPMENT OF THE BLOOD SUPPLY OF THE BRAIN 62
2.3 GROSS ANATOMY OF THE VESSELS OF THE BRAIN AND THE SPINAL CORD 62
2.4 VASCULAR IMAGING 65
2.5 ARTERIAL SUPPLY OF THE CEREBRAL CORTEX 68
2.6 THE CIRCLE OF WILLIS AND ITS PERFORATING BRANCHES 70
CLINICAL CASE 2.1 ANEURYSM OF THE ANTERIOR COMMUNICATING ARTERY TON VAN
DER VLIET 74
CLINICAL CASE 2.2 ANEURYSM OF THE POSTERIOR COMMUNICATING ARTERY PIETER
WESSELING 75
2.7 ISCHAEMIC STROKE 75
CLINICAL CASE 2.3 MCA STENOSIS LARS ROEDIGER 78
CLINICAL CASE 2.4 WATERSHED INFARCTION TON VAN DER VLIET 79
CLINICAL CASE 2.5 ISCHAEMIC NECROSIS IN THE MCA TERRITORY PIETER
WESSELING 79
CLINICAL CASE 2.6 BASILAR TIP ANEURYSM/BASILAR THROMBOSIS TON VAN DER
VLIET 80
2.8 ARTERIAL SUPPLY OF THE CAPSULA INTERNA AND THE BASAL GANGLIA 82
CLINICAL CASE 2.7 SMALL-VESSEL DISEASE OF THE LENTICULOSTRIATE ARTERIES
PETER VAN DOMBURG 83
2.9 ARTERIAL SUPPLY OF THE THALAMUS 84
CLINICAL CASE 2.8 THALAMIC STROKE TON VAN DER VLIET 85
CLINICAL CASE 2.9 VARIANTS OF PARAMEDIAN ARTERY OCCLUSION PETER VAN
DOMBURG 86
2.10 ARTERIAL SUPPLY OF THE CEREBELLUM 88
CLINICAL CASE 2.10 CEREBELLAR INFARCTION DUE TO AN ANEURYSM OF THE SCA
TON VAN DER VLIET 90
2.11 ARTERIAL SUPPLY OF THE BRAIN STEM 90
CLINICAL CASE 2.11 A TYPICAL WALLENBERG SYNDROME TON VAN DER VLIET 94
CLINICAL CASE 2.12 LACUNAR INFARCI OF THE PONS PETER VAN DOMBURG 96
2.12 ARTERIAL SUPPLY OF THE SPINAL CORD 96
CLINICAL CASE 2.13 SPINAL CORD INFARCTION DUE TO A CERVICAL TUMOUR TON
VAN DER VLIET 97
2.13 VENOUS DRAINAGE 98
CLINICAL CASE 2.14 V. GALENI MAGNA ANEURYSM TON VAN DER VLIET 101
CLINICAL CASE 2.15 SAGITTAL SINUS THROMBOSIS TON VAN DER VLIET 102
CLINICAL CASE 2.16: STRAIGHT SINUS THROMBOSIS PETER VAN DOMBURG 102
REFERENCES 104
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CONTENTS
CHAPTER 3 NOTES ON TECHNIQUES HANS J. TEN DONKELAAR, DICK STEGEMAN, AND
TON VAN DER VLIET 3.1 INTRODUCTION 107
3.2 TISSUE-STAINING TECHNIQUES 107
3.3 TRACT-TRACING TECHNIQUES 108
3.3.1 FIBRE DISSECTION 108
3.3.2 THE CLASSIC DEGENERATION TECHNIQUES 109
3.3.3 MODERN TRACT-TRACING TECHNIQUES 1 12
3.4 IMMUNOHISTOCHEMICAL TECHNIQUES 113
3.5 ELECTROPHYSIOLOGICAL TECHNIQUES 114
3.5.1 EEG AND MEG 115
3.5.2 EVOKED POTENTIALS 116
3.5.3 TRANSCRANIAL ELECTRICAL AND MAGNETIC STIMULATION 117
3.5.4 ELECTROPHYSIOLOGICAL METHODS FOR MAPPING BRAIN MOTOR AND SENSORY
CIRCUITS 119
3.6 NON-INVASIVE IMAGING TECHNIQUES 121
3.6.1 MR IMAGING 122
3.6.2 DIFFUSION TENSOR IMAGING 123
3.6.3 FUNCTIONAL MRI 125
3.6.4 POSITRON EMISSION TOMOGRAPHY 125
REFERENCES 126
CHAPTER 4 THE SOMATOSENSORY SYSTEM HANS J. TEN DONKELAAR, ANTOINE
KEYSER, AND PETER VAN DOMBURG
4.1 INTRODUCTION 133
4.2 RECEPTORS AND PERIPHERAL PATHWAYS 134
4.2.1 RECEPTORS 135
4.2.2 SEGMENTAI INNERVATION OF THE SKIN 137
CLINICAL CASE 4.1 MERALGIA PARAESTHETICA PETER VAN DOMBURG 143
4.2.3 PERIPHERAL PATHWAYS 144
CLINICAL CASE 4.2 SENSORY NEURONOPATHIES/NEUROPATHIES GERT VAN DIJK 145
4.2.4 LESIONS OF THE DORSAL ROOTS 146
CLINICAL CASE 4.3 NEURALGIC AMYOTROPHY NENS VANALFEN 151
4.3 THE LARGE-FIBRED DORSAL (POSTERIOR) COLUMN-MEDIAL LEMNISCUS PATHWAY
152
4.3.1 DORSAL COLUMN PROJECTIONS 152
CLINICAL CASE 4.4 LATERAL MEDULLARY LESION AFFECTING THE DECUSSATING
MEDIAL LEMNISCUS ENRICO MARANI 155
4.3.2 SENSORY PATHWAYS IN THE DORSOLATERAL FUNICULUS 156
4.3.3 THE SOMATOSENSORY THALAMUS 157
4.3.4 SOMATOSENSORY CORTICAL PROJECTIONS 159
4.3.5 SENSORIMOTOR TRANSITION 164
4.3.6 LESIONS OF THE DORSAL COLUMN-MEDIAL LEMNISCUS SYSTEM 165
CLINICAL CASE 4.5 SENSORY EFFECTS OF LESIONS OF THE POSTERIOR COLUMNS
AFTER GANS (1916) 167
CLINICAL CASE 4.6 LESIONS OF THE MEDIAL LEMNISCUS AFTER KIM (2001) 167
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CONTENTS
CLINICAL CASE 4.7 THE CONTROL OF HAND MOVEMENTS IN A CASE OF
HEMIANAESTHESIA FOLLOWING A PARIETAL LESION AFTER JEANNEROD ET AL.
(1984) 170
CLINICAL CASE 4.8 ISOLATED LOSS OF STEREOGNOSIS PETER VAN DOMBURG 171
4.4 THE SMALL-FIBRED SENSORY PATHWAYS IN THE VENTRAL QUADRANT 172 4.4.1
THE ANTEROLATERAL OR PAIN SYSTEM 172
4.4.1.1 ANTEROGRADE DEGENERATION STUDIES IN HUMANS 172
CLINICAL CASE 4.9 DISTRIBUTION OF ANTEROGRADELY DEGENERATING FIBRES
FOLLOWING ANTEROLATERAL CORDOTOMY AFTER MEHLER (1962) 173
4.4.1.2 NOCICEPTION 173
4.4.1.3 THE GATE CONTROL THEORY 173
4.4.1.4 THE SPINOTHALAMIC TRACTS 173
4.4.2 BRAIN STEM PROJECTIONS 178
4.4.3 THALAMIC AND HYPOTHALAMIC PROJECTIONS 180
4.4.4 CORTICAL TARGETS 181
4.4.5 DESCENDING PAIN MODULATORY SYSTEMS 182
4.4.6 LESIONS OF THE ANTEROLATERAL SYSTEM 182
CLINICAL CASE 4.10 CENTRAL NEUROPATHIC PAIN IN SPINAL CORD LESIONS PETER
VAN DOMBURG 185
CLINICAL CASE 4.11 LESIONS OF THE PAIN SYSTEM FROM MEDULLA TO THALAMUS
PETER VAN DOMBURG 186
CLINICAL CASE 4.12 CENTRAL POST-STROKE PAIN FOLLOWING A CORTICAL INFARCT
PETER VAN DOMBURG 188
4.5 THE TRIGEMINAL SOMATOSENSORY SYSTEM 189
4.5.1 TRIGEMINAL AFFERENTS 189
4.5.2 BRAIN STEM TRIGEMINAL SENSORY NUCLEI 190
4.5.3 THALAMIC PROJECTIONS 192
4.5.4 CORTICAL TARGETS 193
4.5.5 LESIONS OF THE TRIGEMINAL SOMATOSENSORY SYSTEM 193
CLINICAL CASE 4.13 TRIGEMINAL NEURALGIA PETER VAN DOMBURG 194
CLINICAL CASE 4.14 TRIGEMINAL GANGLION OR ROOT COMPRESSION PETER VAN
DOMBURG 195
CLINICAL CASE 4.15 WALLENBERG SYNDROME PETER VAN DOMBURG 197
REFERENCES 198
CHAPTER 5 THE RETICULAR FORMATION AND SOME RELATED NUCLEI PAVEL
PETROVICKY, VERONIKA NEMCOVA, HANS J. TEN DONKELAAR, SEBASTIAAN OVEREEM,
AND PIETER VOS 5.1 INTRODUCTION 211
5.2 CYTOARCHITECTURE, SUBDIVISION AND ORGANIZATION OF THE RETICULAR
FORMATION 212
5.2.1 THE RAPHE NUCLEI 212
5.2.2 THE MEDIAL RETICULAR FORMATION 214
5.2.3 THE LATERAL RETICULAR FORMATION 215
5.3 MONOAMINERGIC NUCLEI 215
5.3.1 SEROTONERGIC CELL GROUPS 215
5.3.2 NORADRENERGIC CELL GROUPS 216
5.4 CHOLINERGIC CELL GROUPS 216
5.4.1 THE PEDUNCULOPONTINE AND LATERODORSAL TEGMENTAL NUCLEI 216
IMAGE 5
CONTENTS
5.4.2 THE BASAL NUCLEUS OF MEYNERT AND ASSOCIATED NUCLEI 218
5.5 FIBRE CONNECTIONS OF THE RETICULAR FORMATION 220
5.6 SLEEP AND WAKEFULNESS 223
5.7 SOME SLEEP DISORDERS 229
CLINICAL CASE 5.1 IDIOPATHIC NARCOLEPSY SEBASTIAAN OVEREEM 230
CLINICAL CASE 5.2 SYMPTOMATIC NARCOLEPSY TOM SCAMMELL 231
CLINICAL CASE 5.3 SLEEP DISTURBANCES IN PD SEBASTIAAN OVEREEM 233
5.8 DISORDERS OF CONSCIOUSNESS 234
CLINICAL CASE 5.4 UNCAL HEMIATION SYNDROME PIETER VOS 235
CLINICAL CASE 5.5 TRANSTENTORIAL UNCAL/TONSILLAR HERNIATION PIETER VOS
237
CLINICAL CASE 5.6 "TOP OF THE BASILAR" SYNDROME PIETER VOS 238
CLINICAL CASE 5.7 HIGH PONTINE/LOWER MIDBRAIN LESIONS LEADING TO COMA
AFTER PARVIZI AND DAMASIO (2003) 240
CLINICAL CASE 5.8 AKINETIC MUTISM PETER VAN DOMBURG 240
CLINICAL CASE 5.9 LOCKED-IN SYNDROME PIETER VOS 242
REFERENCES 242
CHAPTER 6 THE CRANIAL NERVES HANSJ. TEN DONKELAAR, JOHANNES R.M.
CRUYSBERG, TON VAN DER VLIET, PETER VAN DOMBURG, AND WILLY O. RENIER
6.1 INTRODUCTION 249
6.2 A FEW NOTES ON THE DEVELOPMENT OF THE BRAIN STEM 250
CLINICAL CASE 6.1 CONGENITAL CRANIAL DYSINNERVATION DISORDERS JOHANNES
R.M. CRUYSBERG 253
6.3 THE OCULOMOTOR, TROCHLEAR AND ABDUCENS NERVES 254
CLINICAL CASE 6.2 LESIONS OF INDIVIDUAL OCULAR MOTOR NERVES JOHANNES
R.M. CRUYSBERG 257
CLINICAL CASE 6.3 LESIONS OF THE OCULOMOTOR NERVE AND NUCLEUS PETER VAN
DOMBURG 261
CLINICAL CASE 6.4 SINUS CAVERNOSUS SYNDROMES PETER VAN DOMBURG 262
6.4 EYE MOVEMENTS 264
6.4.1 OVERVIEW 264
6.4.2 THE VESTIBULO-OPTOKINETIC SYSTEM 264
6.4.3 BRAIN STEM CONTROL OF HORIZONTAL AND VERTICAL EYE MOVEMENTS 266
CLINICAL CASE 6.5 BRAIN STEM LESIONS AFFECTING HORIZONTAL EYE MOVEMENTS:
INO PETER VAN DOMBURG 268
CLINICAL CASE 6.6 BRAIN STEM LESIONS AFFECTING VERTICAL EYE MOVEMENTS:
PARINAUD SYNDROME PETER VAN DOMBURG 269
6.4.4 VOLUNTARY CONTROL OF EYE MOVEMENTS 270
CLINICAL CASE 6.7 PARALYSIS OF SACCADES AND PURSUIT MARTIN LAEMMERN 271
IMAGE 6
CONTENTS
6.5 THE TRIGEMINAL NERVE 272
6.5.1 THE SENSORY PART OF THE TRIGEMINAL NERVE 272
CLINICAL CASE 6.8 TRIGEMINAL NEURALGIA PETER VAN DOMBURG 274
6.5.2 THE MOTOR PART OF THE TRIGEMINAL NERVE 274
CLINICAL CASE 6.9 LATE BLINK REFLEX CHANGES IN LATERAL MEDULLARY LESIONS
MAJIDARAMIDEH 277
6.6 THE FACIAL NERVE 279
CLINICAL CASE 6.10 FACIAL NERVE PARALYSIS WILLY O. RENIER 280
CLINICAL CASE 6.11 CONGENITAL FACIAL PALSY HARRIETTE VERZIJL AND MARTIN
LAMMENS 281
6.7 THE GUSTATORY SYSTEM 283
6.8 THE VESTIBULOCOCHLEAR NERVE 284
6.8.1 THE VESTIBULAR NERVE AND NUCLEI 287
6.8.2 FIBRE CONNECTIONS OF THE VESTIBULAR NUCLEI 287
6.8.3 FUNCTIONAL AND PATHOPHYSIOLOGICAL ASPECTS OF VESTIBULAR CONTROL
288 CLINICAL CASE 6.12 PERIPHERAL VESTIBULAR DISORDERS MYRTHEHOL 290
CLINICAL CASE 6.13 CENTRAL VESTIBULAR DISORDERS AFTER DIETERICH ET AL.
(2005) 292
6.9 THE GLOSSOPHARYNGEAL, VAGAI AND ACCESSORY CRANIAL NERVES 293 6.9.1
THE IXTH, XTH AND XLTH CRANIAL NERVES 293
CLINICAL CASE 6.14 LESIONS OF THE IXTH, XTH AND XLTH CRANIAL NERVES
WILLY O. RENIER 294
6.9.2 SWALLOWING 295
CLINICAL CASE 6.15 DYSPHAGIA PETER VAN DOMBURG 296
6.10 THE HYPOGLOSSAL NERVE 297
CLINICAL CASE 6.16 HYPOGLOSSAL PARESIS WILLY O. RENIER 298
REFERENCES 298
CHAPTER 7 THE AUDITORY SYSTEM HANSJ. TEN DONKELAAR AND KIMITAKA KAGA 7.1
INTRODUCTION 305
7.2 THE COCHLEA AND THE COCHLEAR NERVE 306
7.2.1 THE MIDDLE EAR AND THE COCHLEA: MECHANICAL TRANSMISSION OF SOUND
306 7.2.2 COCHLEAR HAIR CELLS: TRANSDUCTION AND AMPLIFICATION 308
7.2.3 SPIRAL GANGLION CELLS AND THE COCHLEAR NERVE: NEURAL TRANSMISSION
308 7.2.4 THE AUDITORY PERIPHERY: GENERATION OF EVOKED ACTIVITY 308
7.2.5 HEARING LOSS 309
CLINICAL CASE 7.1 CEREBELLOPONTINE ANGLE TUMOUR KIMITAKA KAGA 310
7.3 THE BRAIN STEM AUDITORY SYSTEM 312
7.3.1 THE COCHLEAR NUCLEI: DIVERSIFICATION OF COCHLEAR INPUT 312
7.3.2 THE SUPERIOR OLIVARY COMPLEX: RECREATION OF AUDITORY SPACE 313
7.3.3 THE UPPER BRAIN STEM: INTEGRATION OF ASCENDING AUDITORY PATHWAY
313 7.3.4 BRAIN STEM TOPOGRAPHY: GENERATION OF EVOKED POTENTIALS 314
CLINICAL CASE 7.2 IMPAIRED SOUND LOCALIZATION FOLLOWING A MIDLINE
PONTINE LESION AFTER LEVINE AND HAEUSLER (2001) 314
7.4 THE FOREBRAIN AUDITORY SYSTEM 315
7.4.1 THE AUDITORY THALAMUS 315
7.4.2 THE ACOUSTIC RADIATION 315
7.4.3 THE AUDITORY CORTEX: SEQUENTIAL LEVELS OF AUDITORY PROCESSING 316
IMAGE 7
CONTENTS
7.4.4 AUDITORY DISORDERS RELATED TO STROKE 319
CLINICAL CASE 7.3 AUDITORY AGNOSIA CAUSED BY BILATERAL LESIONS
RESTRICTED TO THE AUDITORY RADIATIONS KIMITAKA KAGA 321
CLINICAL CASE 7.4 NEUROPATHOLOGY OF AUDITORY AGNOSIA FOLLOWING BILATERAL
TEMPORAL LOBE INFARCTION KIMITAKA KAGA 322
CLINICAL CASE 7.5 AUDITORY HALLUCINATIONS FOLLOWING A METASTASIS IN
HESCHL'S GYRUS PETER VAN DOMBURG 324
7.5 THE DESCENDING AUDITORY SYSTEM 325
REFERENCES 326
CHAPTER 8 THE VISUAL SYSTEM HANSJ. TEN DONKELAAR AND JOHANNES R.M.
CRUYSBERG
8.1 INTRODUCTION 331
8.2 ANATOMY AND IMAGING OF THE VISUAL SYSTEM 332
8.2.1 THE RETINA 332
CLINICAL CASE 8.1 HEREDITARY RETINAL DYSTROPHIES JOHANNES R.M. CRUYSBERG
335
8.2.2 THE OPTIC NERVE, THE OPTIC CHIASM AND THE OPTIC TRACT 336
CLINICAL CASE 8.2 ISOLATED ABSENCE OF THE OPTIC CHIASM NOMDO JANSONIUS
AND TON VAN DER VLIET 338
8.2.3 THE LATERAL GENICULATE BODY 338
CLINICAL CASE 8.3 SELECTIVE TRANSNEURONAL DEGENERATION OF THE LGB AFTER
ENUCLEATION AKIRAHORI 339
8.2.4 THE OPTIC RADIATION 341
8.2.5 THE SUPERIOR COLLICULUS AND THE PULVINAR 341
8.2.6 THE PRETECTUM AND THE PUPILLARY LIGHT REFLEX 343
CLINICAL CASE 8.4 LESIONS OF THE PUPILLARY LIGHT REFLEX PATHWAY MARIA
VAN GENDEREN AND JOHANNES R.M. CRUYSBERG 345
CLINICAL CASE 8.5 HOMER SYNDROME JOHANNES R.M. CRUYSBERG 346
8.3 THE VISUAL CORTEX 346
8.3.1 THE STRIATE CORTEX 346
CLINICAL CASE 8.6 MELAS AND CENTRAL BLINDNESS MICHEL WILLEMSEN 349
8.3.2 EXTRASTRIATE AND VISUAL ASSOCIATION CORTICES 349
8.4 THE RETINOGENICULOCORTICAL PATHWAY AND TYPICAL VISUAL-FIELD DEFECTS
351 CLINICAL CASE 8.7 THE SPECTRUM OF VISUAL-FIELD DEFECTS JOHANNES R.M.
CRUYSBERG 353
CLINICAL CASE 8.8 ALTITUDINAL HEMIANOPIA MARTIN LAEMMERN 355
8.5 THE EXTRASTRIATE VISUAL CORTEX AND ABNORMALITIES OF COMPLEX VISUAL
PERCEPTION 356
8.5.1 DORSAL PATHWAY LESIONS 357
CLINICAL CASE 8.9 BALINT SYNDROME TON VAN DER VLIET 357
8.5.2 VENTRAL PATHWAY LESIONS 358
CLINICAL CASE 8.10 CEREBRAL ACHROMATOPSIA JOHANNES R.M. CRUYSBERG AND
ANTOINE KEYSER 359
CLINICAL CASE 8.11 PAROXYSMAL VISUAL PHENOMENA PETER VAN DOMBURG 360
REFERENCES 361
IMAGE 8
CONTENTS
CHAPTER 9 MOTOR SYSTEMS HANSJ. TEN DONKELAAR 9.1 INTRODUCTION 367
9.2 THE PERIPHERAL MOTOR SYSTEM 368
9.2.1 THE PERIPHERAL OR LMNS 368
9.2.2 MOTOR UNITS AND MUSCLE UNITS 370
9.2.3 MOTOR UNIT-MUSCLE UNIT ASSOCIATION 372
9.2.4 REFLEX PATHWAYS IN THE SPINAL CORD 374
CLINICAL CASE 9.1 MANUAL MOTOR CONTROL IN A DEAFFERENTED MAN JOHN
ROTHWELL 376
9.2.5 MUSCLE TONE 377
9.2.6 LESIONS OF PERIPHERAL MOTONEURONS 378
9.2.6.1 PLEXUS LESIONS 378
9.2.6.2 DISEASES OF THE MOTOR UNIT 379
9.2.6.3 MOTONEURON DISEASE 380
CLINICAL CASE 9.2 LESIONS OF THE BRACHIAL PLEXUS ANTOINE KEYSER 381
CLINICAL CASE 9.3 DIABETIC LUMBOSACRAL PLEXUS NEUROPATHY NENS VANALFEN
382
9.3 GAIT AND POSTURE 382
CLINICAL CASE 9.4 ATROPHY OF INTRINSIC HAND MUSCLES IN PATIENTS WITH
PARIETAL LESIONS AFTER OP DE COUL (1970) 383
CLINICAL CASE 9.5 THE SPECTRUM OF MND JUERGEN SCHELHAAS AND BENNO KUESTERS
385
CLINICAL CASE 9.6 A JUVENILE ALS CASE JAN GEELEN, WILLY O. RENIER AND
HENK TER LAAK 386
9.3.1 PHYSIOLOGICAL BASIS OF HUMAN LOCOMOTION 388
9.3.2 AFFERENT CONTROL 389
9.3.3 SUPRASPINAL CONTROL 389
9.3.4 SPINAL CORD INJURIES 391
CLINICAL CASE 9.7 THE BROWN-SEQUARD SYNDROME ANTOINE KEYSER 392
9.3.5 GAIT DISORDERS 393
CLINICAL CASE 9.8 GAIT DISORDERS PETER VAN DOMBURG 394
9.3.6 POSTURE 395
9.4 CENTRAL CONTROL OF MOVEMENT 396
9.4.1 DESCENDING PATHWAYS TO THE SPINAL CORD 396
9.4.2 LONG CORTICOFUGAL PATHWAYS 401
9.4.2.1 CORTICOBULBAR FIBRES 401
CLINICAL CASE 9.9 CORTICOBULBAR PROJECTIONS AFTER KUYPERS (1958) 402
CLINICAL CASE 9.10 ABERRANT CORTICOFACIAL PROJECTIONS PETER URBAN 404
9.4.2.2 THE INTERNAL CAPSULE 406
9.4.2.3 THE CORTICOSPINAL TRACT 406
CLINICAL CASE 9.11 COURSE AND SITE OF TERMINATION OF CORTICOSPINAL
PROJECTIONS AFTER SCHOEN (1969) 412
9.4.2.4 INDIRECT CORTICOSPINAL PROJECTIONS 414
CLINICAL CASE 9.12 INTERRUPTION OF A RELAY OF CORTICOSPINAL EXCITATION
BY A SPINAL LESION AT C6-C7 EMMANUEL PIERROT-DESEILLIGNY 415
IMAGE 9
CONTENTS XV
9.4.3 LESIONS OF SUPRASPINAL MOTOR STRUCTURES 416
9.4.3.1 LESIONS OF THE CORTICOSPINAL TRACT IN HUMANS 416
CLINICAL CASE 9.13 LESIONS OF THE CORTICOSPINAL TRACT: OVERVIEW PIETER
WESSELING AND PETER VAN DOMBURG 417
9.4.3.2 THE EFFECTS OF SECTIONING OF THE PYRAMIDAL TRACT IN MONKEYS 419
9.4.3.3 HUMAN MANIPULATORY SKILLS 420
9.4.3.4 PURE LESIONS OF THE HUMAN PYRAMIDAL TRACT 421
CLINICAL CASE 9.14 PURE MOTOR HEMIPLEGIA DUE TO A MEDULLARY PYRAMID
LESION AFTER LEESTMA AND NORONHA (1976) 421
9.4.3.5 TRANSECTION OF DESCENDING BRAIN STEM PATHWAYS 422
9.4.4 HUMAN CORTICAL MOTOR AREAS 424
9.4.4.1 CORTICAL MOTOR AREAS IN MONKEYS 424
9.4.4.2 HUMAN CORTICAL MOTOR AREAS 424
9.4.4.3 LESIONS OF THE PRECENTRAI GYRUS 429
CLINICAL CASE 9.15 RECOVERY OF FUNCTION FOLLOWING A LESION OF THE MOTOR
CORTEX AFTER FOERSTER (1936) 430
9.4.4.4 LESIONS OF THE SMA 430
9.4.4.5 LESIONS OF THE PMC 430
CLINICAL CASE 9.16 LESIONS OF THE PREMOTOR VERSUS MOTOR CORTICES AFTER
FREUND AND HUMMELSHEIM (1985) 432
9.4.5 HIGHER-ORDER MOTOR CONTROL 000
9.4.6 LESIONS OF HIGHER-ORDER MOTOR CENTRES 432
CLINICAL CASE 9.17 VISUOMOTOR ATAXIA AFTER RONDOT ET AL. (1977) 434
CLINICAL CASE 9.18 APRAXIA PETER VAN DOMBURG 436
REFERENCES 437
CHAPTER 10 THE CEREBELLUM HANSJ. TEN DONKELAAR, BART VAN DE WARRENBURG,
MARTIN LAMMENS, AND PIETER WESSELING 10.1 INTRODUCTION 449
10.2 A FEW NOTES ON THE DEVELOPMENT OF THE CEREBELLUM 450
CLINICAL CASE 10.1 MIDLINE OR VERMIS MALFORMATIONS HANS J. TEN DONKELAAR
452
CLINICAL CASE 10.2 PONTOCEREBELLAR HYPOPLASIAS MARTIN LAMMENS 454
10.3 GROSS MORPHOLOGY, SUBDIVISION AND COMPARTMENTALIZATION 454 10.4 THE
DEEP CEREBELLAR NUCLEI 456
10.5 THE CEREBELLAR PEDUNCLES 456
10.6 CEREBELLAR AFFERENT CONNECTIONS 457
10.6.1 THE SPINOCEREBELLAR TRACTS 457
10.6.2 VESTIBULOCEREBELLAR PROJECTIONS 459
10.6.3 OLIVOCEREBELLAR PROJECTIONS 459
CLINICAL CASE 10.3 THE HUMAN CENTRAL AND MEDIAL TEGMENTAL TRACTS JAN
VOOGD 463
10.6.4 CORTICOPONTOCEREBELLAR PROJECTIONS 464
CLINICAL CASE 10.4 CORTICOPONTINE PROJECTIONS IN THE HUMAN BRAIN JAN
VOOGD 467
10.6.5 HYPOTHALAMOCEREBELLAR PROJECTIONS 10.7 CEREBELLAR OUTPUT: MOTOR
AND COGNITIVE CHANNELS 469
10.7.1 THE BRACHIUM CONJUNCTIVUM 469
CLINICAL CASE 10.5 THE HUMAN BRACHIUM CONJUNCTIVUM AFTER GEBBINK (1967)
469
IMAGE 10
CONTENTS
10.7.2 CEREBELLOTHALAMOCORTICAL PROJECTIONS 470
10.7.3 THE UNCINATE TRACT 472
10.7.4 OPEN VERSUS CLOSED LOOPS 472
10.8 CEREBELLAR DYSFUNCTION 474
10.9 ATAXIA: PATHOPHYSIOLOGY AND CLINICAL ASPECTS 476
10.9.1 SIGNS OF CEREBELLAR DISEASE 476
CLINICAL CASE 10.6 HOLMES OR RUBRAL TREMOR PETER VAN DOMBURG 477
10.9.2 HEREDITARY SPINOCEREBELLAR ATAXIAS 478
CLINICAL CASE 10.7 FRIEDREICH ATAXIA ARNULF KOEPPEN 478
CLINICAL CASE 10.8 SPINOCEREBELLAR ATAXIA TYPE 3 (SCA3) BART VAN DE
WARRENBURG 480
CLINICAL CASE 10.9 MULTIPLE SYSTEM ATROPHY, CEREBELLAR VARIANT (MSA-C)
PIETER WESSELING 480
10.9.3 ACQUIRED ATAXIAS 482
CLINICAL CASE 10.10 PARANEOPLASTIC CEREBELLAR DEGENERATION BART VAN DE
WARRENBURG 482
10.9.4 VASCULAR LESIONS 483
CLINICAL CASE 10.11 CAUDAL PARAMEDIAN MIDBRAIN SYNDROME LUIGI
MOSSUTO-AGATIELLO 483
10.9.5 ATAXIC HEMIPARESIS 484
CLINICAL CASE 10.12 A CASE OF THALAMIC ATAXIA PETER VAN DOMBURG 485
10.10 THE CEREBELLAR COGNITIVE AFFECTIVE SYNDROME 485
CLINICAL CASE 10.13 CEREBELLAR MUTISM MICHEL WILLEMSEN 486
REFERENCES 487
CHAPTER 11 BASAL GANGLIA HANSJ. TEN DONKELAAR, BART VAN DE WARRENBURG,
MICHEL WILLEMSEN, BENNO KUESTERS, YOSHIO HASHIZUME, ANDAKIRA HORI
11.1 INTRODUCTION 495
11.2 SUBDIVISION, CYTOARCHITECTURE AND BASIC CIRCUITRY 499
11.2.1 THE STRIATUM 499
11.2.2 THE PALLIDAL COMPLEX 501
11.2.3 THE SUBTHALAMIC NUCLEUS 502
11.2.4 THE MOTOR THALAMUS 502
11.2.5 THE SUBSTANTIA NIGRA AND THE VENTRAL TEGMENTAL AREA 504
11.2.6 THE DIRECT AND INDIRECT BASAL GANGLIA PATHWAYS 505
11.3 FUNCTIONAL BASAL GANGLIA CONNECTIONS 507
11.3.1 THE CORTICOSTRIATAL PROJECTION SYSTEM 507
11.3.2 THE STRIATOFUGAL SYSTEM 510
11.3.3 THE OUTPUT STRUCTURES OF THE BASAL GANGLIA 511
11.3.3.1 OVERVIEW 511
11.3.3.2 PALLIDOFUGAL FIBRES 512
CLINICAL CASE 11.1 ANTEROGRADE FIBRE DEGENERATION FOLLOWING PALLIDAL
LESIONS AFTER GEBBINK (1967) 514
11.3.3.3 THE SUBTHALAMIC NUCLEUS 515
11.3.3.4 THE ZONA INCERTA 515
11.3.3.5 THE PEDUNCULOPONTINE TEGMENTAL NUCLEUS 515
IMAGE 11
CONTENTS
11.3.3.6 UPDATED MODEL OF BASAL GANGLIA CIRCUITRY 516
11.3.4 THE NIGROSTRIATAL SYSTEM 516
11.3.5 LESIONS OF THE BASAL GANGLIA 516
CLINICAL CASE 11.2 SELECTIVE VULNERABILITY OF THE BASAL GANGLIA I:
OVERVIEW MICHEL WILLEMSEN 519
CLINICAL CASE 11.3 SELECTIVE VULNERABILITY OF THE BASAL GANGLIA II:
FAMILIAL STRIATAL DEGENERATION MARTIN LAMMENS 521
CLINICAL CASE 11.4 SELECTIVE VULNERABILITY OF THE BASAL GANGLIA III:
LEIGH SYNDROME MICHEL WILLEMSEN AND MARTIN LAMMENS 522
CLINICAL CASE 11.5 MOTOR FUNCTION IN A PATIENT WITH BILATERAL LESIONS OF
THE GLOBUS PALLIDUS ROBHAAXMA 524
CLINICAL CASE 11.6 HEMIBALLISM AKIRAHORI 524
CLINICAL CASE 11.7 DENTATORUBROPALLIDOLUYSIAN ATROPHY MAYA MIMURO, MARI
YOSHIDA AND YOSHIO HASHIZUME 525
11.4 PATHOPHYSIOLOGY OF BASAL GANGLIA DISORDERS 528
11.4.1 PARKINSON DISEASE 528
11.4.2 HEMIBALLISMUS 533
CLINICAL CASE 11.8 POSTTRAUMATIC TREMOR WITHOUT PARKINSONISM IN A
PATIENT WITH COMPLETE CONTRALATERAL LOSS OF THE NIGROSTRIATAL PATHWAY
JAN ZIJLMANS 533
CLINICAL CASE 11.9 THE CLINICAL SPECTRUM OF PD AND RELATED DISORDERS: I
JUVENILE PD AND VASCULAR PARKINSONISM BART VAN DE WARRENBURG AND PETER
VAN DOMBURG 534
CLINICAL CASE 11.10 THE CLINICAL SPECTRUM OF PD AND RELATED DISORDERS
II: PARKINSON-PLUS DISORDERS BART VAN DE WARRENBURG 535
11.4.3 CHOREA 537
11.4.4 DYSTONIA 539
11.4.5 OBSESSIVE-COMPULSIVE DISORDERS 539
11.5 NEUROPATHOLOGY OF BASAL GANGLIA DISORDERS 539
11.5.1 PARKINSON DISEASE 540
CLINICAL CASE 11.11 NEUROPATHOLOGICAL ASSESSMENT OF HYPOKINETIC MOVEMENT
DISORDERS BENNO KUESTERS 544
11.5.2 PARKINSON-PLUS DISORDERS 547
CLINICAL CASE 11.12 PROGRESSIVE SUPRANUCLEAR PALSY AKIRA HORI AND YOSHIO
HASHIZUME 548
CLINICAL CASE 11.13 CORTICOBASAL DEGENERATION AKIRA HORI AND YOSHIO
HASHIZUME 550
11.5.3 HUNTINGTON DISEASE 552
REFERENCES 553
CHAPTER 12 THE AUTONOMIE NERVOUS SYSTEM HANSJ. TEN DONKELAAR, VERONIKA
NEMCOVA, MARTIN LAMMENS, SEBASTIAAN OVEREEM, AND ANTOINE KEYSET
12.1 INTRODUCTION 565
12.2 PERIPHERAL COMPONENTS OF THE AUTONOMIE NERVOUS SYSTEM 565
IMAGE 12
XVIII CONTENTS
12.2.1 PRE- AND POSTGANGLIONIC NEURONS 566
12.2.2 THE THORACOLUMBAR OR SYMPATHETIC DIVISION 566
12.2.3 THE CRANIOSACRAL OR PARASYMPATHETIC DIVISION 567
12.2.4 AFFERENT VISCERAL FIBRES 569
12.2.5 THE ENTERIC NERVOUS SYSTEM 571
CLINICAL CASE 12.1 AGANGLIONOSIS MARTIN LAMMENS 573
CLINICAL CASE 12.2 GANGLIONEURONITIS IN PARANEOPLASTIC SYNDROME MARTIN
LAMMENS 574
12.2.6 AUTONOMIE INNERVATION OF THE VISCERA 575
12.2.7 SOME CASES OF AUTONOMIE FAILURE 576
CLINICAL CASE 12.3 PURE AUTONOMIE FAILURE ERWIN VAN INGELGHEM, MICHEL
VAN ZANDIJCKE AND MARTIN LAMMENS 577 CLINICAL CASE 12.4 AUTONOMIE
DYSFUNCTION BY A SPINAL CONUS LESION ANTOINE KEYSER 578
12.3 CENTRAL COMPONENTS OF THE AUTONOMIE NERVOUS SYSTEM 578
12.3.1 ASCENDING VISCEROSENSORY PROJECTIONS 578
12.3.2 THE CENTRAL AUTONOMIE NETWORK 579
12.3.3 NEURAL CONTROL OF BLOOD PRESSURE 580
CLINICAL CASE 12.5 DENERVATION OF CAROTID BARO- AND CHEMORECEPTORS HENRI
TIMMERS 582
12.3.4 NEURAL CONTROL OF BREATHING 583
CLINICAL CASE 12.6 CNS LESIONS PRODUCING ABNORMAL BREATHING PATTERNS
SEBASTIAAN OVEREEM, DIRK PEVERNAGIE, GERALD HENGSTMAN AND BENNO KUESTERS
585
CLINICAL CASE 12.7 DISORDERS OF CHEMICAL CONTROL OF BREATHING I:
SLEEP/CENTRAL APNOEA SEBASTIAAN OVEREEM AND DIRK PEVERNAGIE 588
CLINICAL CASE 12.8 DISORDERS OF CHEMICAL CONTROL OF BREATHING II: SIDS
ANNA LAVEZZI 590
12.3.5 NEURAL CONTROL OF MICTURITION 591
CLINICAL CASE 12.9 DISORDERS OF MICTURITION RYUGI SAKAKIBARA, HIROAKI
YAGUCHI AND ICHIRO YABE 596
REFERENCES 598
CHAPTER 13 THE HYPOTHALAMUS AND HYPOTHALAMOHYPOPHYSIAL SYSTEMS HANS J.
TEN DONKELAAR AND AKIRA HORI 13.1 INTRODUCTION 603
13.2 ANATOMICAL ORGANIZATION 604
13.2.1 BOUNDARIES AND SUBDIVISION 604
13.2.2 HYPOTHALAMIC NUCLEI 606
CLINICAL CASE 13.1 VENTROMEDIAL HYPOTHALAMUS SYNDROME AFTER REEVES AND
PLUM (1969) 609
13.2.3 THE PITUITARY GLAND 610
CLINICAL CASE 13.2 PERSISTENT CRANIOPHARYNGEAL CANAL WITH PHARYNGOSELLAR
PITUITARY AKIRA HORI 611
CLINICAL CASE 13.3 CRANIOPHARYNGIOMA PIETER WESSELING 612
13.2.4 CIRCUMVENTRICULAR ORGANS 612
13.3 FIBRE CONNECTIONS 614
13.3.1 THEFORNIX 616
CLINICAL CASE 13.4 ANTEROGRADE TRANSNEURONAL ATROPHY OF THE MAMMILLARY
BODY FOLLOWING A HIPPOCAMPUS INFARCTION AKIRA HORI 616
IMAGE 13
CONTENTS
13.3.2 THE MAMMILLOTHALAMIC TRACT AND THE MAMMILLARY PEDUNCLE 617
CLINICAL CASE 13.5 UNILATERAL ATROPHY OF THE MAMMILLARY BODY DUE TO
DAMAGE OF THE MAMMILLOTHALAMIC TRACT AKIRAHORI 618
13.3.3 THE STRIA TERMINALIS 618
13.3.4 THE MEDIAL FOREBRAIN BUNDLE 618
13.4 HYPOTHALAMOHYPOPHYSIAL PATHWAYS 620
13.4.1 THE MAGNOCELLULAR SECRETORY SYSTEM 620
13.4.2 THE PARVOCELLULAR SECRETORY SYSTEM 621
13.5 FUNCTIONAL ORGANIZATION OF THE HYPOTHALAMUS 621
13.5.1 FEEDING 622
13.5.2 REPRODUCTION 622
CLINICAL CASE 13.6 PALLISTER-HALL SYNDROME AKIRAHORI 624
13.5.3 THERMOREGULATION 625
13.5.4 SLEEP 625
REFERENCES 626
CHAPTER 14 THE LIMBIC SYSTEM HANS J. TEN DONKELAAR, JIFI BRABEC, MARTIN
LAMMENS, BENNO KUESTERS, YOSHIO HASHIZUME, AND AKIRA HORI
14.1 INTRODUCTION 633
14.2 THE CONCEPT OF THE LIMBIC SYSTEM 634
14.3 THE OLFACTORY SYSTEM (THE RHINENCEPHALON) 636
14.3.1 THE MAIN OLFACTORY SYSTEM 636
CLINICAL CASE 14.1 OLFACTORY GROOVE MENINGIOMA PETER VAN DOMBURG 638
14.3.2 THE ACCESSORY OLFACTORY SYSTEM 639
14.4 THE BASAL FOREBRAIN 640
14.4.1 THE SEPTUM 643
14.4.2 THE VENTRAL STRIATOPALLIDAL SYSTEM 643
14.4.3 THE EXTENDED AMYGDALA 644
14.4.4 THE MAGNOCELLULAR BASAL FOREBRAIN SYSTEM 644
14.5 THE AMYGDALA 645
14.5.1 SUBDIVISION 645
14.5.2 FIBRE CONNECTIONS 647
14.5.3 FUNCTIONAL ASPECTS 650
14.5.4 LESIONS OF THE AMYGDALA 652
CLINICAL CASE 14.2 PARTIAL KLUEVER-BUCY SYNDROME AKIRA HORI 654
CLINICAL CASE 14.3 BILATERAL DEGENERATION OF THE AMYGDALA AFTER ADOLPHS
ET AL. (1995) 656
14.6 ANATOMY OF NEUROPSYCHIATRIE DISORDERS 653
14.7 THE HIPPOCAMPUS 658
14.7.1 SUBDIVISION 658
14.7.2 FIBRE CONNECTIONS 661
14.7.3 SOME FUNCTIONAL ASPECTS 665
CLINICAL CASE 14.4 ANTEROGRADE TRANSNEURONAL ATROPHY OF THE MAMMILLARY
BODY AKIRA HORI 666
CLINICAL CASE 14.5 DIFFUSE INFILTRATIVE GROWTH ALONG HIPPOCAMPAL
PROJECTIONS PIETER WESSELING 668
14.7.4 TEMPORAL LOBE EPILEPSY 669
IMAGE 14
XX CONTENTS
14.8 MEMORY AND MEMORY DISORDERS 669
CLINICAL CASE 14.6 TEMPORAL LOBE EPILEPSY (TLE) OLAF SCHIJNS AND MARTIN
LAMMENS 670
14.8.1 A TAXONOMY OF MEMORY 672
14.8.2 BRAIN REGIONS DAMAGED IN AMNESIA 672
CLINICAL CASE 14.7 ACUTE WERNICKE ENCEPHALOPATHY AKIRA HORI AND YOSHIO
HASHIZUME 676
CLINICAL CASE 14.8 CHRONIC WERNICKE ENCEPHALOPATHY AKIRA HORI AND YOSHIO
HASHIZUME 677
CLINICAL CASE 14.9 CASE HM AFTER CORKIN ET AL. (1997) 678
CLINICAL CASE 14.10 CASE WH AFTER REMPEL-CLOWER ET AL. (1996) 680
CLINICAL CASE 14.11 UNILATERAL HERPES SIMPLEX ENCEPHALITIS OF THE
AMYGDALA AND THE ROSTRAL HIPPOCAMPUS PETER VAN DOMBURG 681
CLINICAL CASE 14.12 THALAMIC AMNESIA YSBRAND VAN DER WERF 682
14.9 NEUROANATOMY OF AD 684
14.9.1 A FEW NOTES ON DEMENTIA 684
14.9.2 THE NEUROANATOMICAL BASIS FOR MEMORY IMPAIRMENT IN AD 684
CLINICAL CASE 14.13 THE NEUROPATHOLOGICAL ASSESSMENT OF AD BENNO KUESTERS
689
CLINICAL CASE 14.14 ALZHEIMER DISEASE HIROYASU AKATSU, YOSHIO HASHIZUME
AND AKIRA HORI 693
CLINICAL CASE 14.15 ARGYROPHILIC GRAIN DISEASE HIROYASU AKATSU, YOSHIO
HASHIZUME, MAYA MIMURO AND AKIRA HORI 696 REFERENCES 699
CHAPTER 15 THE CEREBRAL CORTEX AND COMPLEX CEREBRAL FUNCTIONS HANSJ. TEN
DONKELAAR, PETER VAN DOMBURG, PAUL ELING, ANTOINE KEYSER, BENNO KUESTERS,
AND AKIRA HORI
15.1 INTRODUCTION 712
15.2 CORTICAL MAPS 712
15.3 THE ISOCORTEX 718
15.3.1 THE FRONTAL LOBE 720
CLINICAL CASE 15.1 PREFRONTAL DISCONNECTION WITH FORCED HYPERPHASIA AND
ENVIRONMENTAL DEPENDENCY PETER VAN DOMBURG 726
15.3.2 THE PARIETAL LOBE 726
CLINICAL CASE 15.2 GRASPING DISORDERS FERDINAND BINKOFSKI 731
15.3.3 THE TEMPORAL LOBE 732
15.3.4 THE OCCIPITAL LOBE 733
15.3.5 THE INSULAR LOBE 735
15.4 CORTICOCORTICAL PROJECTIONS 736
15.4.1 LONG ASSOCIATION FIBRE TRACTS 737
15.4.2 COMMISSURAL CONNECTIONS 741
15.4.2.1 A FEW NOTES ON THE DEVELOPMENT OF THE CORPUS CALLOSUM 742
CLINICAL CASE 15.3 SOME DEVELOPMENTAL DISORDERS OF THE CORPUS CALLOSUM
BERIT VERBIST AND GERARD VAN NOORT 742
15.4.2.2 THE CORPUS CALLOSUM AND THE ANTERIOR COMMISSURE 744
CLINICAL CASE 15.4 CALLOSAL SYNDROME AFTER RESECTION OF A LARGE
ARTERIOVENOUS MALFORMATION GEA DROST 744
IMAGE 15
CONTENTS XXI
15.4.3 WHITE MATTER DISORDERS 745
CLINICAL CASE 15.5 WHITE MATTER DISORDERS I: PVL MICHEL WILLEMSEN 746
CLINICAL CASE 15.6 WHITE MATTER DISORDERS II: METACHROMATIC
LEUKODYSTROPHY MARTIN LAMMENS 747
CLINICAL CASE 15.7 WHITE MATTERS DISORDERS III: BINSWANGER FRANK ERIK DE
LEEUW, HIROYASU AKATSU, YOSHIO HASHIZUME AND AKIRA HORI 749
CLINICAL CASE 15.8 WHITE MATTER DISORDERS IV: CADASIL MARTIN LAMMENS 754
15.5 HEMISPHERIC DIFFERENCES 755
15.5.1 LATERALITY OR ASYMMETRY? 755
15.5.2 LATERALIZATION OF VISUOSPATIAL PROCESSING 756
CLINICAL CASE 15.9 LEFT HEMINEGLECT, THE CASE OF FEDERICO FELLINI AFTER
CANTAGALLO AND DELLA SALA (1998) 758
15.5.3 LATERALIZATION OF AUDITORY PROCESSING 759
15.5.4 ANATOMICAL AND FUNCTIONAL DIFFERENCES 759
15.6 LANGUAGE AND THE BRAIN 760
15.6.1 THE CLASSIC, CLINICOPATHOLOGICAL APPROACH 760
CLINICAL CASE 15.10 LANGUAGE DISORDERS (BROCA, WERNICKE, GLOBAL,
CONDUCTION AND TRANSCORTICAL TYPES OF APHASIA) ANTOINE KEYSER 762
15.6.2 SYNTAX 764
CLINICAL CASE 15.11 SYNTACTIC APPROACH TO BROCA APHASIA PAULELING 765
15.6.3 LANGUAGE PATHWAYS 766
15.6.4 PRIMARY PROGRESSIVE APHASIA 767
CLINICAL CASE 15.12 LOGOPENIC VARIANT OF PPA PETER VAN DOMBURG 768
15.6.5 READING AND WRITING 770
15.7 DISCONNECTION SYNDROMES 770
15.7.1 LANGUAGE NETWORK DISORDERS 771
CLINICAL CASE 15.13 BILINGUAL LANGUAGE PROCESSING AFTER A LESION IN THE
LEFT THALAMIC AND TEMPORAL REGIONS ANTOINE KEYSER 773
CLINICAL CASE 15.14 DEJERINE'S CASE ON PURE ALEXIA AFTER DEJERINE (1892)
773
15.7.2 PRAXIS NETWORK DISORDERS 775
CLINICAL CASE 15.15 PRIMARY PROGRESSIVE APRAXIA PETER VAN DOMBURG 776
15.7.3 VISUAL NETWORK DISORDERS 777
CLINICAL CASE 15.16 BALINT SYNDROME PETER VAN DOMBURG 778
CLINICAL CASE 15.17 PROSOPAGNOSIA PETER VAN DOMBURG 779
15.8 THE NEUROANATOMICAL BASIS OF COGNITIVE IMPAIRMENT IN THE PRIMARY
DEGENERATIVE DEMENTIAS 780
15.8.1 THE CLINICAL PROFILE OF PDDS 780
CLINICAL CASE 15.18 THE ENIGMA OF LOBAR DEGENERATION PETER VAN DOMBURG
781
CLINICAL CASE 15.19 PROGRESSIVE COMPORTMENTAL/EXECUTIVE DYSFUNCTION
(BEHAVIOURAL VARIANT OF FTD) PETER VAN DOMBURG 784
CLINICAL CASE 15.20 PRIMARY PROGRESSIVE APHASIA PETER VAN DOMBURG 785
IMAGE 16
CONTENTS
CLINICAL CASE 15.21 PROGRESSIVE AMNESTIC DYSFUNCTION (AD) PETER VAN
DOMBURG 788
15.8.2 ALZHEIMER DISEASE 790
CLINICAL CASE 15.22 NEUROPATHOLOGICAL ASSESSMENT OF PDDS (CONSENSUS
CRITERIA) BENNO KUESTERS 790
15.8.3 FRONTOTEMPORAL LOBAR DEGENERATION 792
CLINICAL CASE 15.23 FRONTOTEMPORAL LOBAR DEGENERATION HENNIE
SCHOONDERWALDT AND PIETER WESSELING 793
CLINICAL CASE 15.24 DEMENTIA OF LEWY BODY TYPE (DLB) HIROYASU AKATSU,
YOSHIO HASHIZUME, MAYA MIMURO AND AKIRA HORI 795 15.8.4 DEMENTIA WITH
LEWY BODIES 797
REFERENCES 798
INDEX 811 |
| any_adam_object | 1 |
| author_GND | (DE-588)121740056 |
| building | Verbundindex |
| bvnumber | BV039966206 |
| classification_rvk | CZ 1100 XG 1700 YG 1700 |
| ctrlnum | (OCoLC)724822014 (DE-599)DNB1009499254 |
| dewey-full | 611.8 616.8047 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 611 - Human anatomy, cytology, histology 616 - Diseases |
| dewey-raw | 611.8 616.8047 |
| dewey-search | 611.8 616.8047 |
| dewey-sort | 3611.8 |
| dewey-tens | 610 - Medicine and health |
| discipline | Psychologie Medizin |
| format | Book |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV039966206 |
| illustrated | Illustrated |
| indexdate | 2024-07-21T00:28:05Z |
| institution | BVB |
| isbn | 9783642191336 3642191339 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-024823843 |
| oclc_num | 724822014 |
| open_access_boolean | |
| owner | DE-11 DE-355 DE-BY-UBR |
| owner_facet | DE-11 DE-355 DE-BY-UBR |
| physical | XXIV, 834 S. Ill., graph. Darst. 29 cm |
| publishDate | 2011 |
| publishDateSearch | 2011 |
| publishDateSort | 2011 |
| publisher | Springer |
| record_format | marc |
| spelling | Clinical neuroanatomy brain circuitry and its disorders Hans J. ten Donkelaar. In co-operation with: Jiři Brabec ... Berlin [u.a.] Springer 2011 XXIV, 834 S. Ill., graph. Darst. 29 cm txt rdacontent n rdamedia nc rdacarrier Literaturangaben Neuroanatomie (DE-588)4171577-9 gnd rswk-swf Neuropathologie (DE-588)4171594-9 gnd rswk-swf Zentralnervensystem (DE-588)4067637-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Zentralnervensystem (DE-588)4067637-7 s Neuroanatomie (DE-588)4171577-9 s Neuropathologie (DE-588)4171594-9 s DE-604 Donkelaar, Hendrik J. ten 1946- Sonstige (DE-588)121740056 oth Erscheint auch als Online-Ausgabe Clinical Neuroanatomy X:MVB text/html http://deposit.dnb.de/cgi-bin/dokserv?id=3650281&prov=M&dok_var=1&dok_ext=htm Inhaltstext DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024823843&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Clinical neuroanatomy brain circuitry and its disorders Neuroanatomie (DE-588)4171577-9 gnd Neuropathologie (DE-588)4171594-9 gnd Zentralnervensystem (DE-588)4067637-7 gnd |
| subject_GND | (DE-588)4171577-9 (DE-588)4171594-9 (DE-588)4067637-7 (DE-588)4143413-4 |
| title | Clinical neuroanatomy brain circuitry and its disorders |
| title_auth | Clinical neuroanatomy brain circuitry and its disorders |
| title_exact_search | Clinical neuroanatomy brain circuitry and its disorders |
| title_full | Clinical neuroanatomy brain circuitry and its disorders Hans J. ten Donkelaar. In co-operation with: Jiři Brabec ... |
| title_fullStr | Clinical neuroanatomy brain circuitry and its disorders Hans J. ten Donkelaar. In co-operation with: Jiři Brabec ... |
| title_full_unstemmed | Clinical neuroanatomy brain circuitry and its disorders Hans J. ten Donkelaar. In co-operation with: Jiři Brabec ... |
| title_short | Clinical neuroanatomy |
| title_sort | clinical neuroanatomy brain circuitry and its disorders |
| title_sub | brain circuitry and its disorders |
| topic | Neuroanatomie (DE-588)4171577-9 gnd Neuropathologie (DE-588)4171594-9 gnd Zentralnervensystem (DE-588)4067637-7 gnd |
| topic_facet | Neuroanatomie Neuropathologie Zentralnervensystem Aufsatzsammlung |
| url | http://deposit.dnb.de/cgi-bin/dokserv?id=3650281&prov=M&dok_var=1&dok_ext=htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024823843&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT donkelaarhendrikjten clinicalneuroanatomybraincircuitryanditsdisorders |