Kinase inhibitors: methods and protocols
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Humana Pr.
2012
|
| Schriftenreihe: | Methods in molecular biology
795 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XI, 256 S. graph. Darst. |
| ISBN: | 1617793361 9781617793363 |
Internformat
MARC
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Datensatz im Suchindex
| _version_ | 1804148936064106496 |
|---|---|
| adam_text | Titel: Kinase inhibitors
Autor: Küster, Bernhard
Jahr: 2012
Contents
Preface.............................................................. p
Contributors.......................................................... ix
1 Targeting Cancer with Small-Molecular-Weight Kinase Inhibitors.............. 1
Doriano Fabbro, Sandra W. Cowan-Jacob, Henrik Mobitz,
and Georg Martiny-Baron
2 Small-Molecule Protein and Lipid Kinase Inhibitors in Inflammation
and Specific Models for Their Evaluation................................ 35
Matthias Gaestel andAlexey Kotlyarov
3 Measuring the Activity of Leucine-Rich Repeat Kinase 2:
A Kinase Involved in Parkinson s Disease................................ 45
Byoung Dae Lee, Xiaojie Li, Ted M. Dawson, and Valina L. Dawson
4 Measuring PI3K Lipid Kinase Activity................................... 55
Elisa Ciraolo, Alessia Perino, and Emilio Hirsch
5 A Fluorescence Polarization Assay for the Discovery of Inhibitors
of the Polo-Box Domain of Polo-Like Kinase 1............................ 69
Wolfgang Reindl, Klaus Strebhardt, and Thorsten Berg
6 Assessment of Hepatotoxicity Potential of Drug Candidate Molecules
Including Kinase Inhibitors by Hepatocyte Imaging Assay Technology
and Bile Flux Imaging Assay Technology................................ 83
JinghaiJ. Xu, Margaret C. Dunn, Arthur R. Smith, and Eric S. Tien
7 Kinase Inhibitor Selectivity Profiling Using Differential Scanning Fluorimetry..... 109
Oleg Fedorov, Frank H. Niesen, and Stefan Knapp
8 Chemoproteomic Characterization of Protein Kinase Inhibitors
Using Immobilized ATP............................................. 119
James S. Duncan, Timothy A.J. Haystead, and David W. Litchfield
9 Proteome-Wide Identification of Staurosporine-Binding Kinases
Using Capture Compound Mass Spectrometry............................ 135
Jenny J. Fischer, Olivia Y. Graebner (neé Baessler), and Mathias Dreger
10 Affinity Purification of Proteins Binding to Kinase Inhibitors Immobilized
on Self-Assembling Monolayers....................................... 149
Marcus Bantscheff, Scott Hobson, and Bernhard Küster
11 Kinase Inhibitor Profiling Using Chemoproteomics........................ 161
Markus Schirle, Eugene G Petrella, Scott M. Brittain, David Schwalb,
Edmund Harrington, Ivan Cornella-Taracido, and John A. Tallarico
12 Covalent Cross-Linking of Kinases with Their Corresponding
Peptide Substrates.................................................. 179
Alexander V. Statsuk and Kevan M. Shokat
viii Contents
13 Receptor Tyrosine Kinase Inhibitor Profiling Using Bead-Based
Multiplex Sandwich Immunoassays..................................... 191
Oliver Pbtz, Nicole Schneiderhan-Marra, Tanja Henzler,
Thomas Herget, and Thomas O. Joos
14 Monitoring Phosphoproteomic Response to Targeted Kinase Inhibitors
Using Reverse-Phase Protein Microarrays................................ 203
Gabriela Lavezzari and Mark R. Lackner
15 Measuring Phosphorylation-Specific Changes in Response to Kinase Inhibitors
in Mammalian Cells Using Quantitative Proteomics........................ 217
Nurhan Özlü, Marc Kirchner, and Judith Jebanathirajah Steen
16 Investigation of Acquired Resistance to EGFR-Targeted Therapies
in Lung Cancer Using cDNA Microarrays................................ 233
Kian Kani, Rafaella Sordella, and Parag Mallick
Index............................................................... 255
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| id | DE-604.BV039961181 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T00:15:03Z |
| institution | BVB |
| isbn | 1617793361 9781617793363 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-024818922 |
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| physical | XI, 256 S. graph. Darst. |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | Humana Pr. |
| record_format | marc |
| series | Methods in molecular biology |
| series2 | Methods in molecular biology Springer protocols |
| spelling | Kinase inhibitors methods and protocols ed. by Bernhard Küster New York [u.a.] Humana Pr. 2012 XI, 256 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 795 Springer protocols Methode (DE-588)4038971-6 gnd rswk-swf Kinasen (DE-588)4268693-3 gnd rswk-swf Enzyminhibitor (DE-588)4152479-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Kinasen (DE-588)4268693-3 s Enzyminhibitor (DE-588)4152479-2 s Methode (DE-588)4038971-6 s b DE-604 Küster, Bernhard Sonstige oth Methods in molecular biology 795 (DE-604)BV035362695 795 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024818922&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Kinase inhibitors methods and protocols Methods in molecular biology Methode (DE-588)4038971-6 gnd Kinasen (DE-588)4268693-3 gnd Enzyminhibitor (DE-588)4152479-2 gnd |
| subject_GND | (DE-588)4038971-6 (DE-588)4268693-3 (DE-588)4152479-2 (DE-588)4143413-4 |
| title | Kinase inhibitors methods and protocols |
| title_auth | Kinase inhibitors methods and protocols |
| title_exact_search | Kinase inhibitors methods and protocols |
| title_full | Kinase inhibitors methods and protocols ed. by Bernhard Küster |
| title_fullStr | Kinase inhibitors methods and protocols ed. by Bernhard Küster |
| title_full_unstemmed | Kinase inhibitors methods and protocols ed. by Bernhard Küster |
| title_short | Kinase inhibitors |
| title_sort | kinase inhibitors methods and protocols |
| title_sub | methods and protocols |
| topic | Methode (DE-588)4038971-6 gnd Kinasen (DE-588)4268693-3 gnd Enzyminhibitor (DE-588)4152479-2 gnd |
| topic_facet | Methode Kinasen Enzyminhibitor Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024818922&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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