Transfusion and transplantation science:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Oxford [u.a.]
Oxford Univ. Press
2013
|
| Schriftenreihe: | Fundamentals of biomedical science
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIII, 290 S. Ill., graph. Darst. |
| ISBN: | 9780199533282 0199533288 |
Internformat
MARC
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| 007 | t | ||
| 008 | 120228s2013 ad|| |||| 00||| eng d | ||
| 020 | |a 9780199533282 |9 978-0-19-953328-2 | ||
| 020 | |a 0199533288 |9 0-19-953328-8 | ||
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| 245 | 1 | 0 | |a Transfusion and transplantation science |c ed. by Robin Knight |
| 246 | 1 | 3 | |a Transfusion & transplantation science |
| 264 | 1 | |a Oxford [u.a.] |b Oxford Univ. Press |c 2013 | |
| 300 | |a XIII, 290 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Fundamentals of biomedical science | |
| 650 | 0 | 7 | |a Bluttransfusion |0 (DE-588)4007293-9 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Bluttransfusion |0 (DE-588)4007293-9 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Knight, Robin |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024779027&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
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Datensatz im Suchindex
| _version_ | 1804148880653156352 |
|---|---|
| adam_text | i
Introduction
to Basic Immunology
and Techniques
Robin Knight
Introduction
1
1
Л
Basic immunology and techniques
4
1.2
Antibody structure
6
1.3
Antibody function
8
1.4
Antigen-antibody reactions
9
1.5
Antibody mediated red cell destruction
10
1.6
In vitro detection of antigen-
antibody reactions
13
1.7
Techniques
17
Chapter summary
18
2
Human Erythrocyte Antigens or
Blood Groups
Malcolm Needs
19
Introduction
19
2.1
The ABO, H, and Lewis blood group systems
21
2.2
The Lewis blood group system and
secretor
26
2.3
The MNS blood group system
27
2.4
The Rh, RHAG, and LW blood group systems
29
2.5
The Lutheran blood group system
2.6
The
Kell
and Kx blood group systems
2.7
The Duffy blood group system
2.8
The Kidd blood group system
2.9
The PI PK blood group system
2.10
Other blood groups
Chapter summary
Further reading
з
Donors and Donation:
Collection and Processing
Lionel Mohabir
Introduction
3.1
Blood donation
35
37
39
3.2
Donor/donation linking
51
3.3
Component preparation
52
3.4
Pathogen reduction
61
3.5
Component validation and labelling
65
Chapter summary
67
Further reading
68
4
Blood Donation Testing
69
Lionel Mohabir
Introduction
69
4.1
Mandatory testing
70
4.2
Additional (discretionary) testing
81
4.3
Microbiology serology testing
84
4.4
Microbiology positive screen and
confirmatory testing
88
4.5
Bacterial contamination
90
4.6
West Nile virus (WNV)
92
4.7
Other threats to the blood supply
93
4.8
Quality control/British working standards
94
Chapter summary
96
Further reading
97
5
Clinical Use of Blood
Components
98
Karen Madgwick and Bill
Chatte
Introduction
98
41
5.1
Structure and function of blood
99
42
42
5.2
Normal physiological response to
anaemia and/or bleeding
99
43
44
5.3
Blood components available and their
appropriate use
100
5.4
Blood products
105
5.5
Special requirements
106
15
5.6
Decision making, who needs a transfusion,
risks and benefits
107
45
5.7
Alternatives to donor blood
109
46
5.8
Case history examples
114
CONTENTS
Chapter summary
115
Further reading
115
6
Compatibility Testing and
Adverse Effects
117
Carol CantweU and Tony Davies
Introduction
117
6.1
Compatibility testing (serological and
non-serological)
118
6.2
Selection of plasma products
126
6.3
Selection of cellular components
127
6.4
Visual inspection and labelling of
the units
128
6.5
Traceability of blood components
129
6.6
Adverse effects of transfusion
129
6.7
Monitoring the patient during transfusion
132
6.8
Investigation of transfusion reactions
134
6.9
Haemovigilance in the UK
136
Chapter summary
140
Further reading
141
7
Immune Red Cell Destruction
142
Robin Knight
Introduction
142
7.1
What is immune (antibody mediated)
red cell destruction?
143
7.2
Clinical significance of red cell antibodies
145
7.3
Haemolytic transfusion reactions
147
7.4
Autoimmune haemolytic anaemias
149
7.5
Haemolysis post-transplantation bone
marrow/stem cell transplant
154
7.6
Haemolytic disease of the newborn or
foetus (HDN)
155
Chapter summary
160
Further reading
160
8
Human Leucocyte Antigens
and Their Clinical Significance
162
Cofin Brown
Introduction
162
8.1
A brief history of transplantation
163
8.2
Human leucocyte antigens
163
8.3
The detection and definition of
human leucocyte antigens,
alíeles,
and
antibodies
170
8.4
Clinical significance of human leucocyte
antigens in transplantation
174
8.5
Clinical significance of human leucocyte
antigens in transfusion
181
Chapter summary
185
Further reading
186
Discussion questions
186
9
Human Platelet Antigens
(ΗΡΑ)
and Human Neutrophil
Antigens (HNA) and Their
Clinical Significance
187
Geoff Lucas
Introduction
188
9.1
Overview of platelet and granulocyte
antigens
188
9.2
Human platelet antigens
(ΗΡΑ)
190
9.3
Human neutrophil antigens (HNA)
196
9.4
Antibody detection
199
9.5
Clinical significance of
ΗΡΑ
alloantibodies
205
9.6
Clinical significance of HNA antibodies
212
Chapter summary
215
Further reading
215
Discussion questions
216
10
Haemopoietic Stem Cell Banking
217
Robert Waiters
Introduction
217
10.1
Stem cells
218
10.2
Major histocompatibility complex and
human lymphocyte antigens
220
10.3
Sources of haemopoietic stem cells
222
10.4
Stem cell collection and processing
224
10.5 Reinfusion
and engraftment
230
10.6
Complications
231
10.7
Health and safety, and statutory
requirements
233
CONTENTS
10.8
The future
of stem cell therapy
234
Chapter summary
235
Further reading
235
n
Tissue Banking
236
Richard Lomas
Introduction
236
11.1
Types of graft
237
11.2
Which tissues are banked and how are
they used?
238
11.3
How are donors selected, screened,
and consented?
240
11.4
How are tissues retrieved?
243
11.5
Tissue processing and preservation
247
11.6
Storage and distribution
254
11.7
The future-regenerative medicine
255
Chapter summary
256
Further reading
257
12
Quality Issues
John Barker and Joan Jones
258
Introduction
258
12.1
Evolution of quality
258
12.2
Quality management systems
261
12.3
Blood safety and quality regulations
264
12.4
The In Vitro Diagnostic Medical
Devices Directive
267
12.5
Clinical laboratory accreditation
267
12.6
The Blood Stocks Management Scheme
268
12.7
Other legislation and regulatory bodies
269
12.8
Guidelines
270
12.9
Haemovigilance
270
Chapter summary
Further reading
271
271
Glossary
Abbreviations
Index
272
276
279
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| id | DE-604.BV039920531 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T00:14:10Z |
| institution | BVB |
| isbn | 9780199533282 0199533288 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-024779027 |
| oclc_num | 780135096 |
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| physical | XIII, 290 S. Ill., graph. Darst. |
| publishDate | 2013 |
| publishDateSearch | 2013 |
| publishDateSort | 2013 |
| publisher | Oxford Univ. Press |
| record_format | marc |
| series2 | Fundamentals of biomedical science |
| spelling | Transfusion and transplantation science ed. by Robin Knight Transfusion & transplantation science Oxford [u.a.] Oxford Univ. Press 2013 XIII, 290 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Fundamentals of biomedical science Bluttransfusion (DE-588)4007293-9 gnd rswk-swf Bluttransfusion (DE-588)4007293-9 s DE-604 Knight, Robin Sonstige oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024779027&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Transfusion and transplantation science Bluttransfusion (DE-588)4007293-9 gnd |
| subject_GND | (DE-588)4007293-9 |
| title | Transfusion and transplantation science |
| title_alt | Transfusion & transplantation science |
| title_auth | Transfusion and transplantation science |
| title_exact_search | Transfusion and transplantation science |
| title_full | Transfusion and transplantation science ed. by Robin Knight |
| title_fullStr | Transfusion and transplantation science ed. by Robin Knight |
| title_full_unstemmed | Transfusion and transplantation science ed. by Robin Knight |
| title_short | Transfusion and transplantation science |
| title_sort | transfusion and transplantation science |
| topic | Bluttransfusion (DE-588)4007293-9 gnd |
| topic_facet | Bluttransfusion |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024779027&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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