Microbial pathogenomics
Microbial pathogenomics:

'Microbial Pathogenomics' contains a unique collection of reviews demonstrating how genomics has revolutionized our understanding of virulence, host-adaptation strategies and the evolution of bacterial pathogens. Current technologies – computational tools and functional approaches to genom...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Weitere Verfasser: Reuse, Hilde de (HerausgeberIn), Bereswill, Stefan (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Basel Karger 2009
Schriftenreihe:Genome dynamics Vol. 6
Schlagworte:
Bacterial genomes
Pathogenic bacteria
Bacteria > genetics
Bacteria > pathogenicity
Genome, Bacterial
Bakterien
Genom
Pathogener Mikroorganismus
Aufsatzsammlung
Online-Zugang:DE-522
DE-12
DE-526
DE-521
DE-1102
DE-1046
DE-1028
DE-573
DE-M347
DE-92
DE-898
DE-859
DE-1049
DE-863
DE-862
DE-M382
DE-70
DE-128
DE-54
DE-22
DE-155
DE-150
DE-91
DE-384
DE-473
DE-19
DE-355
DE-703
DE-20
DE-706
DE-29
DE-739
Volltext
Zusammenfassung:'Microbial Pathogenomics' contains a unique collection of reviews demonstrating how genomics has revolutionized our understanding of virulence, host-adaptation strategies and the evolution of bacterial pathogens. Current technologies – computational tools and functional approaches to genome analysis – are carefully documented and clearly illustrated. These include visualization tools for genome comparison, databases, in silico metabolic reconstructions and function prediction as well as interactomics for the study of protein-protein interactions. The concepts of pan-genomics and reverse vaccinology are introduced as strategies when addressing the challenge presented by bacterial diversity in the prevention and treatment of infectious diseases. The authors explore individual bacterial pathogens and discuss the mechanisms that have contributed to their evolutionary success. Special cases of host adaptation, for example, are illustrated by Helicobacter pylori and 'Mycobacterium tuberculosis' which are human-specific and highly persistent; further bacteria discussed include 'Escherichia coli, Campylobacter, Pseudomonas, Legionella, Bartonella, Burkholderia' and 'Staphylococcus'.'Microbial Pathogenomics' provides the reader with a global view of key aspects and future trends in bacterial pathogenomics and evaluates their impact on the understanding and treatment of infectious diseases. Well illustrated and accessible to both specialists and nonspecialists, it is recommended not only for researchers in microbiology, genomics and biotechnology, but also for lecturers and teachers
Beschreibung:A global view of key aspects and future trends
Beschreibung:1 Online-Ressource (X, 214 Seiten) Illustrationen, Diagramme
ISBN:9783805591935
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