Molecular mechanisms of adult stem cell aging:
There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field.The molecular causes of s...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Basel
Karger
2010
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| Schriftenreihe: | Else Kröner-Fresenius-Symposia
Vol. 1 |
| Schlagworte: | |
| Online-Zugang: | DE-522 DE-12 DE-526 DE-521 DE-1102 DE-1046 DE-1028 DE-573 DE-M347 DE-92 DE-898 DE-859 DE-1049 DE-863 DE-862 DE-M382 DE-70 DE-128 DE-54 DE-22 DE-155 DE-150 DE-91 DE-384 DE-473 DE-19 DE-355 DE-703 DE-20 DE-706 DE-29 DE-739 Volltext |
| Zusammenfassung: | There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field.The molecular causes of stem cell aging remain to be defined. Stem cell aging can involve cell-intrinsic as well as cell-extrinsic alterations affecting the stem cell niche or the macroenvironment. Stem cells have a longer life span than other cell populations and retain a capacity to proliferate and differentiate in adult organs. The aging of adult stem cells plays a key role in the decline of organ maintenance and regenerative potential during aging and during the end stage of chronic diseases. In addition, it can contribute to stem cell transformation and carcinogenesis.Molecular Mechanisms of Adult Stem Cell Aging will appeal to scientists working in the fields such as stem cells, aging, regeneration and cancer. This subject matter should be of interest to physicians and scientists specializing in geriatric medicine, internal medicine, and surgery. It is also likely to be an invaluable resource for medical students and biologists who wish to enhance their understanding of molecular and stem cell biology |
| Beschreibung: | A meeting report of the first international Else Kröner-Fresenius-Symposium on Adult Stem Cell Aging |
| Beschreibung: | 1 Online-Ressource (VIII, 107 Seiten) Illustrationen, Diagramme |
| ISBN: | 9783805592444 |
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| 520 | |a There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field.The molecular causes of stem cell aging remain to be defined. Stem cell aging can involve cell-intrinsic as well as cell-extrinsic alterations affecting the stem cell niche or the macroenvironment. Stem cells have a longer life span than other cell populations and retain a capacity to proliferate and differentiate in adult organs. The aging of adult stem cells plays a key role in the decline of organ maintenance and regenerative potential during aging and during the end stage of chronic diseases. In addition, it can contribute to stem cell transformation and carcinogenesis.Molecular Mechanisms of Adult Stem Cell Aging will appeal to scientists working in the fields such as stem cells, aging, regeneration and cancer. This subject matter should be of interest to physicians and scientists specializing in geriatric medicine, internal medicine, and surgery. It is also likely to be an invaluable resource for medical students and biologists who wish to enhance their understanding of molecular and stem cell biology | ||
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| genre | (DE-588)1071861417 Konferenzschrift 2009 Günzburg gnd-content |
| genre_facet | Konferenzschrift 2009 Günzburg |
| id | DE-604.BV039887152 |
| illustrated | Illustrated |
| indexdate | 2025-03-07T04:01:26Z |
| institution | BVB |
| isbn | 9783805592444 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-024746247 |
| oclc_num | 747900332 |
| open_access_boolean | |
| owner | DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-521 DE-522 DE-526 DE-12 DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-573 DE-859 DE-M347 DE-91 DE-BY-TUM DE-1028 DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046 DE-706 |
| owner_facet | DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-521 DE-522 DE-526 DE-12 DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-573 DE-859 DE-M347 DE-91 DE-BY-TUM DE-1028 DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046 DE-706 |
| physical | 1 Online-Ressource (VIII, 107 Seiten) Illustrationen, Diagramme |
| psigel | ZDB-1-KEB ZDB-1-KEB10 |
| publishDate | 2010 |
| publishDateSearch | 2010 |
| publishDateSort | 2010 |
| publisher | Karger |
| record_format | marc |
| series | Else Kröner-Fresenius-Symposia |
| series2 | Else Kröner-Fresenius-Symposia |
| spellingShingle | Molecular mechanisms of adult stem cell aging Else Kröner-Fresenius-Symposia Adult Stem Cells physiology Congresses Aging Molecular aspects Congresses Cell Aging genetics Congresses Cells Aging Congresses DNA Damage physiology Congresses Stem cells Congresses Telomere genetics Congresses Telomer Molekulargenetik (DE-588)4310952-4 gnd Altern (DE-588)4068596-2 gnd Adulte Stammzelle (DE-588)4699649-7 gnd |
| subject_GND | (DE-588)4310952-4 (DE-588)4068596-2 (DE-588)4699649-7 (DE-588)1071861417 |
| title | Molecular mechanisms of adult stem cell aging |
| title_auth | Molecular mechanisms of adult stem cell aging |
| title_exact_search | Molecular mechanisms of adult stem cell aging |
| title_full | Molecular mechanisms of adult stem cell aging volume editor: Karl Lenhard Rudolph |
| title_fullStr | Molecular mechanisms of adult stem cell aging volume editor: Karl Lenhard Rudolph |
| title_full_unstemmed | Molecular mechanisms of adult stem cell aging volume editor: Karl Lenhard Rudolph |
| title_short | Molecular mechanisms of adult stem cell aging |
| title_sort | molecular mechanisms of adult stem cell aging |
| topic | Adult Stem Cells physiology Congresses Aging Molecular aspects Congresses Cell Aging genetics Congresses Cells Aging Congresses DNA Damage physiology Congresses Stem cells Congresses Telomere genetics Congresses Telomer Molekulargenetik (DE-588)4310952-4 gnd Altern (DE-588)4068596-2 gnd Adulte Stammzelle (DE-588)4699649-7 gnd |
| topic_facet | Adult Stem Cells physiology Congresses Aging Molecular aspects Congresses Cell Aging genetics Congresses Cells Aging Congresses DNA Damage physiology Congresses Stem cells Congresses Telomere genetics Congresses Telomer Molekulargenetik Altern Adulte Stammzelle Konferenzschrift 2009 Günzburg |
| url | https://karger.com/books/book/2672 |
| volume_link | (DE-604)BV041114333 |
| work_keys_str_mv | AT rudolphkarllenhard molecularmechanismsofadultstemcellaging |