Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to div...

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Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Berlin ; Heidelberg [u.a.] Springer 2011
Schriftenreihe:	Epigenetics and human health
Schlagworte:	Medizin Reproduktionsmedizin Epigenetik Gametogenese Medicine Human genetics Reproductive Medicine Aufsatzsammlung
Online-Zugang:	UBT01 Volltext
Zusammenfassung:	Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the 'Epigenetics and Human Health' series discusses the role of epigenetics in human reproduction. The book presents epigenetic transitions that are important at defined stages of gametogenesis and during meiosis. Finally, the authors discusses how in vitro manipulation and culture in assisted reproduction can epigenetically perturb germ cells, and how this can trigger disease phenotypes in the next generation. Conceived towards advanced students, medical professionals and research scientists, this is the first comprehensive textbook on this topic that will serve as a valuable reference during the years to come.
Beschreibung:	1 Online-Ressource
ISBN:	9783642147739
DOI:	10.1007/978-3-642-14773-9