Lymphadenectomy in urologic oncology: indications, controversies and complications
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| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Philadelphia, PA
Saunders
2011
|
| Series: | Urologic clinics of North America
38,4 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | XII S., S. 375 - 523 zahlr. Ill., graph. Darst. 27 cm |
| ISBN: | 9781455710485 |
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| adam_text | Titel: Lymphadenectomy in urologic oncology
Autor: Ghavamian, Reza
Jahr: 2011
Lymphadenectomy in Urologie Oncology: Indications, Controversies and Complications
Contents
Preface
Reza Ghavamian
XI
The History and Anatomy of Urologie Lymphadenectomy 375
Daniel J. Lewinshtein and Christopher R. Porter
The history of urologic lymphadenectomy is rich and diverse. Our current under-
standing of its use and benefits is a product of the hard work of numerous physicians
and scientists from many nations. Standard dissection templates for the various
urologic malignancies are based on a complete understanding of the anatomy of
the lymphatic system, which has developed immensely since Hippocrates first
described the white blood of the lymphatic system while performing an axillary dis-
section. It is hoped that the next 100 years will bring even greater comprehension of
its value and utility.
Role of Lymphadenectomy for Prostate Cancer: Indications and Controversies 387
Jeffrey C. La Rochelle and Christopher L. Amling
Pelvic lymph node dissection is the only reliable technique to detect low-volume
lymph node involvement in prostate cancer. Extended lymph node dissections
that include the internal iliac chain in addition to the external iliac and obturator
packets have shown a significantly higher proportion of patients to have lymphatic
involvement than previously recognized. The improved staging afforded by a more
extended dissection raises several questions. Addressing these questions is the
focus of this review.
Lymphadenectomy for Bladder Cancer: Indications and Controversies 397
Fiona C. Burkhard, Beat Roth, Pascal Zehnder, and Urs E. Studer
Pelvic lymph node dissection (PLND) at the time of cystectomy remains the most ac-
curate method of staging and can have a positive impact on cancer control, and
there is general agreement as to its necessity at the time of surgery. There is, how-
ever, a lack of consensus regarding the terminology of PLND and controversy con-
cerning the optimal extent of lymph node dissection, especially because recent
investigations have suggested a survival benefit with extended PLND.
Feasibility of Minimally Invasive Lymphadenectomy in Bladder and Prostate
Cancer Surgery 407
A. Ari Hakimi and Reza Ghavamian
With the rapid and widespread adoption of minimally invasive procedures (laparo-
scopic and robotic) for the treatment of prostate and bladder cancers in the last
decade, concerns have been raised regarding whether the technique can emulate
the time-tested gold standard open procedures. This article briefly reviews the indi-
cations for lymph node dissection for bladder and prostate cancer, and reviews the
role of extended lymphadenectomy in each procedure. Much of the focus of this
review is on minimally invasive approaches and the technical aspects of the proce-
dures, the feasibility of the robotic technique, and early oncologic outcomes.
Contents
The Role of Lymph Node Dissection in Renal Cell Carcinoma 419
Scott E. DelacroixJr, Brian F. Chapin, and Christopher G.Wood
The role of lymph node dissection (LND) in the staging and treatment of renal cell
carcinoma has long been a topic of debate. The controversy has focused on whether
LND is purely an adjunctive staging procedure or has a therapeutic role in the man-
agement of this disease. Potential benefits include enhanced staging, better selec-
tion for adjuvant therapies/clinical trials, a decrease in recurrence rates, and
improved disease-specific and overall survival. This article reviews the available
literature on LND in renal cell carcinoma and discusses the potential benefits of
aggressive surgical resection in select high-risk patients.
The Emerging Role of Lymphadenectomy in Upper Tract Urothelial Carcinoma 429
Christopher J. Weight and MathewT. Gettman
Within the last decade, there has been an increased focus on lymphadenectomy or
lymph node dissection (LND) in patients with upper tract urothelial carcinoma
(UTUC). Although the data with regards to LND in UTUC are sparse, investigators
are beginning to evaluate the role and define the anatomy to understand how LND
may affect outcomes in patients with UTUC. This article reviews the history of
LND for UTUC, outlines the relative anatomy, and evaluates the arguments and ev-
idence for, and against, LND in patients with UTUC.
The Role of Lymphadenectomy for Testicular Cancer: Indications, Controversies, and
Complications 439
TatumTarin, Brett Carver, and Joel Sheinfeld
Retroperitoneal lymphadenectomy remains an integral component in the multidisci-
plinary management of testicular cancer. Through the evolution of the procedure,
continued refinements have led to diagnostic and therapeutic benefits as well as im-
provements in perioperative and long-term morbidity. This article discusses the sur-
gical management of testicular cancer, specifically addressing the indications,
controversies, and complications of retroperitoneal lymph node dissection for
both low-stage and high-stage disease.
Minimally Invasive Retroperitoneal Lymph Node Dissection for Testicular Cancer 451
Ornob P. Roy, Brian D. Duty, and Louis R. Kavoussi
Testicular cancer is the most common solid organ malignancy in young men be-
tween the ages of 15 and 35. Although much of this increase in survival can be at-
tributed to improvements in systemic chemotherapy, surgery retains a critical role
in the diagnostic and therapeutic management of testicular cancer. Laparoscopic
retroperitoneal lymph node dissection is an effective staging and therapeutic proce-
dure in patients with low-stage testicular cancer. It is an attractive alternative to the
open approach, with faster recovery, improved cosmesis, and reduced post-opera-
tive morbidity driving its application. In experienced hands, it can be used in post-
chemotherapy patients.
Lymphadenectomy in Penile Cancer 459
Simon Horenblas
In contrast to many cancers, squamous cell carcinoma of the penis can be cured de-
spite the presence of lymph node metastases. This characteristic is shared with tes-
ticular cancer. But unlike testicular cancer, penile carcinoma is not chemosensitive
and, therefore, the focus of management has been on surgery. This article ad-
dresses all aspects of imaging and minimally invasive methods of detecting lymph
Contents
node involvement. It focuses on the indications of surgical management of the re-
gional nodes, the extent of the surgery, and its complications. Also, neoadjuvant
therapy is covered.
Novel Imaging Modalities for Lymph Node Imaging in Urologic Oncology 471
Victoria Chernyak
Accurate lymph node staging in genitourinary (GU) malignancies is important for
planning an appropriate treatment and establishing an accurate prognosis. This
article discusses the novel imaging techniques for detection of metastases in various
GU malignancies, including prostate, bladder, penile, and testicular cancers. Dis-
cussion includes nuclear medicine techniques of 18F-fluorodeoxyglucose positron
emission tomography/computed tomography (PET/CT), 11C-choline and 18F-choline
PET/CT, and ProstaScint scanning, as well as sentinel lymph node mapping. Mag-
netic resonance (MR) techniques include lymphotropic nanoparticle-enhanced MR
imaging and diffusion-weighted MR imaging.
Lymphadenectomy in Urologic Oncology: Pathologic Considerations 483
Riley E. Alexander, Ming-Tse Sung, and Liang Cheng
Lymphadenectomy (LAD) is an important staging and treatment modality of onco-
logic surgery. LAD in genitourinary malignancies presents inherent difficulties to
the urologist and pathologist because of the differences in anatomic sites and pri-
mary histologic type. This review focuses on pathologic evaluation and how commu-
nication between urologist and pathologist is necessary to provide optimal care.
Recommendations covering general specimen submission and processing are dis-
cussed, as well as more specific recommendations concerning the kidney, upper
urinary tract, urinary bladder, prostate, testes, and penis. Emerging areas of prog-
nostic significance and the impact that improved molecular techniques are contrib-
uting to diagnostic interpretation are highlighted.
Role of Radiation Therapy for the Treatment of Lymph Nodes in Urologic Malignancies 497
Thomas J. Pugh and Andrew K. Lee
Radiation therapy (RT) represents an important therapeutic component in the man-
agement of genitourinary (GU) malignancies. RT is used to treat patients with proven
involvement of the regional lymph nodes or delivered electively to patients at risk for
occult regional lymph node metastases. Advances in treatment planning and deliv-
ery of various types of RT provide the technology to precisely plan, target, and de-
liver RT with the goal of optimizing the radiation dose to the target while sparing
normal tissue. This article provides an overview of the modalities, indications, and
techniques of RT for treatment of the lymphatic basins in GU malignancies.
Complications of Lymphadenectomy in Urologic Surgery 507
Steve K.Williams and Farhang Rabbani
Lymphadenectomy in urologic surgery provides accurate staging and may be ther-
apeutic in some patients with lymph node metastases. In addition to the associated
cost, pelvic lymph node dissection (PLND) has the potential for morbidity. This arti-
cle focuses on the complications associated with PLND, including lymphocele,
thromboembolic events, ureteral injury, nerve injury, vascular injury, and lymphede-
ma. With improvements in surgical technique and perioperative care, the morbidity
associated with lymphadenectomy may be minimized.
Index 519
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| spelling | Lymphadenectomy in urologic oncology indications, controversies and complications guest ed. Reza Ghavamian Philadelphia, PA Saunders 2011 XII S., S. 375 - 523 zahlr. Ill., graph. Darst. 27 cm txt rdacontent n rdamedia nc rdacarrier Urologic clinics of North America 38,4 Includes bibliographical references and index Genitourinary organs / Tumors Prostate / Biopsy Prostate / Cancer / Cytopathology Lymph nodes / Biopsy Bladder / Cancer / Diagnosis Urologische Onkologie (DE-588)4199201-5 gnd rswk-swf Lymphknotenresektion (DE-588)4168372-9 gnd rswk-swf Lymphknotenresektion (DE-588)4168372-9 s Urologische Onkologie (DE-588)4199201-5 s DE-604 Ghavamian, Reza Sonstige (DE-588)141981237 oth Urologic clinics of North America 38,4 (DE-604)BV000001584 38,4 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024632579&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Lymphadenectomy in urologic oncology indications, controversies and complications Urologic clinics of North America Genitourinary organs / Tumors Prostate / Biopsy Prostate / Cancer / Cytopathology Lymph nodes / Biopsy Bladder / Cancer / Diagnosis Urologische Onkologie (DE-588)4199201-5 gnd Lymphknotenresektion (DE-588)4168372-9 gnd |
| subject_GND | (DE-588)4199201-5 (DE-588)4168372-9 |
| title | Lymphadenectomy in urologic oncology indications, controversies and complications |
| title_auth | Lymphadenectomy in urologic oncology indications, controversies and complications |
| title_exact_search | Lymphadenectomy in urologic oncology indications, controversies and complications |
| title_full | Lymphadenectomy in urologic oncology indications, controversies and complications guest ed. Reza Ghavamian |
| title_fullStr | Lymphadenectomy in urologic oncology indications, controversies and complications guest ed. Reza Ghavamian |
| title_full_unstemmed | Lymphadenectomy in urologic oncology indications, controversies and complications guest ed. Reza Ghavamian |
| title_short | Lymphadenectomy in urologic oncology |
| title_sort | lymphadenectomy in urologic oncology indications controversies and complications |
| title_sub | indications, controversies and complications |
| topic | Genitourinary organs / Tumors Prostate / Biopsy Prostate / Cancer / Cytopathology Lymph nodes / Biopsy Bladder / Cancer / Diagnosis Urologische Onkologie (DE-588)4199201-5 gnd Lymphknotenresektion (DE-588)4168372-9 gnd |
| topic_facet | Genitourinary organs / Tumors Prostate / Biopsy Prostate / Cancer / Cytopathology Lymph nodes / Biopsy Bladder / Cancer / Diagnosis Urologische Onkologie Lymphknotenresektion |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024632579&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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