Mechanics of the cell:
Gespeichert in:
1. Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Cambridge [u.a.]
Cambridge Univ. Press
2012
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Ausgabe: | 2. ed. |
Schlagworte: | |
Online-Zugang: | Cover image Inhaltsverzeichnis |
Beschreibung: | XIV, 608 S. Ill., graph. Darst. |
ISBN: | 9780521113762 9780521130691 |
Internformat
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Datensatz im Suchindex
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adam_text | Titel: Mechanics of the cell
Autor: Boal, David H
Jahr: 2012
Contents
Preface page ix
List of symbols xi
1 Introduction to the cell 1
1.1 Designs for a cell 4
1.2 Cell shapes, sizes and structures 9
1.3 Biomaterials: soft strings and sheets 15
1.4 Forces inside and outside the cell 19
Summary 23
2 Soft materials and fluids 25
2.1 Fluctuations at the cellular scale 25
2.2 Movement in a viscous fluid 30
2.3 Random walks 37
2.4 Diffusion 41
2.5 Fluctuations and correlations 47
Summary 51
Problems 54
Parti Rods and ropes 61
3 Polymers 63
3.1 Polymers and simple biofilaments 63
3.2 Mathematical description of flexible rods 68
3.3 Sizes of polymer chains 75
3.4 Entropic elasticity 80
3.5 Buckling 85
3.6 Measurements of bending resistance 90
Summary 97
Problems 98
4 Complex filaments 105
4.1 The structure of complex filaments 106
4.2 Torsion, twist and writhe 110
4.3 Measurements of torsional rigidity 118
4.4 Stretching of folded polymers 123
4.5 Protein and RNA folding - concepts 127
4.6 Models for polymer folding 133
Summary 142
Problems 144
5 Two-dimensional networks 151
5.1 Soft networks in the cell 151
5.2 Elasticity in two dimensions 156
5.3 Isotropic networks 163
5.4 Networks with low coordination number 168
5.5 Membrane-associated networks 173
Summary 180
Problems 182
6 Three-dimensional networks 194
6.1 Networks of biological rods and ropes 194
6.2 Elasticity in three dimensions 199
6.3 Entropic networks 205
6.4 Network percolation and failure 209
6.5 Semiflexible polymer solutions 214
6.6 Rheology of cytoskeletal components 221
Summary 229
Problems 230
Part II Membranes 241
7 Biomembranes 243
7.1 Membranes, walls and lamina 243
7.2 Self-assembly of amphiphiles 250
7.3 Bilayer compression resistance 257
7.4 Bilayer bending resistance 263
7.5 Edge energy 268
7.6 Cell walls and sheaths 274
Summary 280
Problems 282
8 Membrane undulations 292
8.1 Thermal fluctuations in membrane shape 292
8.2 Mathematics of curvature 294
8.3 Membrane bending and persistence length 299
8.4 Scaling of polymers and membranes 305
8.5 Measurement of membrane undulations 313
Summary 319
Problems 321
9 Intermembrane and electrostatic forces 326
9.1 Interactions between membranes 326
9.2 Charged plate in an electrolyte 330
9.3 van der Waals and electrostatic interactions 337
9.4 Entropic repulsion of sheets and polymers 346
9.5 Adhesion 352
Summary 361
Problems 363
Part III The whole cell 371
10 The simplest cells 373
10.1 Cell shapes 373
10.2 Energetics of thin shells 375
10.3 Pure bilayer systems 381
10.4 Vesicles and red blood cells 390
10.5 Bacteria 397
Summary 403
Problems 405
11 Dynamic filaments 412
11.1 Movement in the cell 412
11.2 Polymerization of actin and tubulin 418
11.3 Molecular motors 428
11.4 Forces from filaments 435
11.5 Cell propulsion 439
Summary 446
Problems 448
12 Growth and division 454
12.1 Overview of the division cycle 455
12.2 Growth of rods and cocci 462
12.3 Asymmetry and asynchrony in cell division 469
12.4 Transcription and replication 476
12.5 Forces arising in cell division 485
Summary 490
Problems 492
13 Signals and switches 496
13.1 Axons and the action potential 496
13.2 Signal propagation in nerves 503
13.3 Rate equations: switches and stability 509
13.4 Molecular basis of regulation 513
Summary 520
Problems 523
Appendix A Animal cells and tissues 525
Appendix B The cell s molecular building blocks 531
Appendix C Elementary statistical mechanics 539
Appendix D Elasticity 546
Glossary 554
References 565
Index 603
|
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spelling | Boal, David H. 1948- Verfasser (DE-588)132203774 aut Mechanics of the cell David Boal 2. ed. Cambridge [u.a.] Cambridge Univ. Press 2012 XIV, 608 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Cells Mechanical properties Physical biochemistry SCIENCE / Life Sciences / Biophysics bisacsh Biomechanik (DE-588)4006880-8 gnd rswk-swf Zelle (DE-588)4067537-3 gnd rswk-swf Zelle (DE-588)4067537-3 s Biomechanik (DE-588)4006880-8 s DE-604 http://assets.cambridge.org/97805211/13762/cover/9780521113762.jpg Cover image HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024630729&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Boal, David H. 1948- Mechanics of the cell Cells Mechanical properties Physical biochemistry SCIENCE / Life Sciences / Biophysics bisacsh Biomechanik (DE-588)4006880-8 gnd Zelle (DE-588)4067537-3 gnd |
subject_GND | (DE-588)4006880-8 (DE-588)4067537-3 |
title | Mechanics of the cell |
title_auth | Mechanics of the cell |
title_exact_search | Mechanics of the cell |
title_full | Mechanics of the cell David Boal |
title_fullStr | Mechanics of the cell David Boal |
title_full_unstemmed | Mechanics of the cell David Boal |
title_short | Mechanics of the cell |
title_sort | mechanics of the cell |
topic | Cells Mechanical properties Physical biochemistry SCIENCE / Life Sciences / Biophysics bisacsh Biomechanik (DE-588)4006880-8 gnd Zelle (DE-588)4067537-3 gnd |
topic_facet | Cells Mechanical properties Physical biochemistry SCIENCE / Life Sciences / Biophysics Biomechanik Zelle |
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