Drug discovery and evaluation: methods in clinical pharmacology: with 95 tables
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Berlin [u.a.]
Springer
2011
|
| Schriftenreihe: | Springer reference
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XII, 564 S. Ill., graph. Darst. 27 cm |
| ISBN: | 9783540898900 9783540898917 9783540898924 |
Internformat
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| 020 | |a 9783540898917 |c eISBN |9 978-3-540-89891-7 | ||
| 020 | |a 9783540898924 |c print and electronic bundle |9 978-3-540-89892-4 | ||
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| 245 | 1 | 0 | |a Drug discovery and evaluation: methods in clinical pharmacology |b with 95 tables |c Hans Gerhard Vogel ... (eds.) |
| 264 | 1 | |a Berlin [u.a.] |b Springer |c 2011 | |
| 300 | |a XII, 564 S. |b Ill., graph. Darst. |c 27 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
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| 650 | 0 | 7 | |a Klinisches Experiment |0 (DE-588)4164223-5 |2 gnd |9 rswk-swf |
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| 689 | 0 | 1 | |a Klinisches Experiment |0 (DE-588)4164223-5 |D s |
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| 700 | 1 | |a Vogel, H. Gerhard |d 1927- |0 (DE-588)173094597 |4 edt | |
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Datensatz im Suchindex
| _version_ | 1804148531656654848 |
|---|---|
| adam_text | IMAGE 1
TABLE OF CONTENTS
LIST OF CONTRIBUTORS X
SECTION A INTRODUCTION
A.1 GENERAL INTRODUCTION 3
HANS GERHARD VOGEL
SECTION B CLINICAL PHARMACOKINETICS
B.1 INTRODUCTION 7
JOCHEN MAAS
B.2 DOSE FINDING IN SINGLE DOSE STUDIES BY ALLOMETRIC SCALING 9
TOBIAS PAEHLER- JOCHEN MAAS
B.3 MULTIPLE DOSE STUDIES 15
STEVEN G. WOOLFREY * JAMES GILMOUR MORRISON
B.4 DOSE LINEARITY AND PROPORTIONALITY 23
TANJA EISENBLAETTER * LENORE TEICHEN
B.5 EFFECTS OF FOOD INTAKE 41
ROLAND WESCH
B.6 SPECIAL POPULATIONS: PROFILING THE EFFECT OF OBESITY ON DRUG
DISPOSITION AND PHARMACODYNAMICS 49
JAMES GILMOUR MORRISON
B.7 SPECIAL POPULATIONS: RENAL IMPAIRMENT 55
GERARD SANDERINK * GARETH SHACKLETON * JOCHEN MAAS * JAMES GILMOUR
MORRISON
B.8 SPECIAL POPULATIONS: HEPATIC IMPAIRMENT 63
GERARD SANDERINK
B.9 SPECIAL POPULATIONS: PROTEIN BINDING ASPECTS 67
GARETH SHACKLETON
B.10 THE HUMAN ADME STUDY 73
ULRICH KUERZEL * VOLKER KRONE * MANFRED ZIMMER- GARETH SHACKLETON
B.11 SYNTHESIS OF RADIOLABELED COMPOUNDS FOR CLINICAL STUDIES 105
JENS ATZRODT * JOHN ALLEN
BIBLIOGRAFISCHE INFORMATIONEN HTTP://D-NB.INFO/991010515
DIGITALISIERT DURCH
IMAGE 2
TABLE OF CONTENTS
B.12 DRUG-DRUG INTERACTION STUDIES 119
WOLFGANG SCHMIDER- XAVIER BOULENC
B.13 IN VITRO/LN VIVO CORRELATION FOR DRUG-DRUG INTERACTIONS 133
XAVIER BOULENC * WOLFGANG SCHMIDER * OLIVIER BARBERAN
B.14 SPECIFIE STUDIES FOR FORMULATION DEVELOPMENT 161
ROLAND WESCH
B.15 ABSOLUTE AND RELATIVE BIOAVAILABILITY 173
ROLAND WESCH
B.16 BIOEQUIVALENCE 181
GRAHAM LOCKWOOD * ROBERT KRINGLE
B.17 POPULATION PHARMACOKINETICS IN CLINICAL PHARMACOLOGY 189
WILLI WEBER- JEAN-MARIE MARTINEZ * DIETHER RUEPPEL * GRAHAM LOCKWOOD
B.18 BIOANALYSIS OF CLINICAL STUDIES 207
JOERN KRAUSE * RONALD SCHMIDT
B.19 BIOMARKER DEFINITION AND VALIDATION DURING DRUG DEVELOPMENT 223
SIBYLLE HESS * MARIE-LAURE OZOUX * MARTIN GERL
B.20 TOXICOKINETICS AND SAFETY RATIOS 245
KARL-HEINZ LEHR
B.21 IN VITRO/LN VIVO CORRELATION FOR TRANSPORTERS 251
DIETMAR WEITZ
B.22 RELEVANCE OF TRANSPORTERS IN CLINICAL STUDIES 265
TANJA EISENBLAETTER
B.23 SPECIFICITIES FOR ONCOLOGY STUDIES 2 91
JAMES GILMOUR MORRISON * STEVEN G. WOOLFREY
B.24 PHARMACOGENOMICS IN AND ITS INFLUENCE ON PHARMACOKINETICS 2 97
GUY MONTAY * JOCHEN MAAS * ROLAND WESCH
B.25 PK/PD APPROACHES 3 13
DIETHER RUEPPEL * WILLI WEBER
SECTION C HUMAN STUDIES IN CLINICAL PHARMACOLOGY
CL METHODOLOGIES OF PD ASSESSMENT: SCALES 3 31
ROMAN GOERTELMEYER
C.2 METHODOLOGIES OF PHARMACODYNAMIC ASSESSMENT 3 47
CLAUDIA PFEIFFER- PETER RUUS
IMAGE 3
TABLE OF CONTENTS
C.3 PHARMACODYNAMIC DRUG-DRUG INTERACTIONS 367
MARKUS HINDER
C.4 METHODOLOGIES OF SAFETY ASSESSMENT IN CLINICAL PHARMACOLOGY 377
WERNER SEIZ
C.5 PHARMACODYNAMIC EVALUATION: CARDIOVASCULAR METHODOLOGIES 387
CHRISTIAN DE MEY * MARKUS HINDER
C.6 PHARMACODYNAMIC EVALUATION: CNS 423
KEITH A. WESNES * HELEN BROOKER
C.7 PHARMACODYNAMIC EVALUATION: DIABETES METHODOLOGIES 457
REINHARD H. A. BECKER
C.8 PHARMACODYNAMIC EVALUATION: INFLAMMATION/LMMUNOLOGY 483
MARTIN M. SCHOENHARTING
C.9 PHARMACODYNAMIC EVALUATION: ENDOCRINOLOGY 489
JUERGEN SANDOW
CIO PHARMACODYNAMIC EVALUATION: DERMATOLOGY 523
HOLGER KOEHLER
C.11 PHARMACODYNAMIC EVALUATION: ONCOLOGY 533
FRANCOIS LOKIEC
SECTION D REGULATIONS
D.1 DEVELOPMENT OF REGULATIONS FOR SUBMITTING PHARMACOGENOMIC DATA TO
AUTHORITIES 547 KLAUS BURGER
D.2 PHARMACOGENOMIC-GUIDED DRUG DEVELOPMENT 551
KLAUS BURGER
INDEX 559
|
| any_adam_object | 1 |
| author2 | Vogel, H. Gerhard 1927- |
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| author2_variant | h g v hg hgv |
| author_GND | (DE-588)173094597 |
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| building | Verbundindex |
| bvnumber | BV039666084 |
| classification_tum | MED 900f |
| ctrlnum | (OCoLC)700068899 (DE-599)DNB991010515 |
| dewey-full | 615.580724 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.580724 |
| dewey-search | 615.580724 |
| dewey-sort | 3615.580724 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| id | DE-604.BV039666084 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T00:08:37Z |
| institution | BVB |
| isbn | 9783540898900 9783540898917 9783540898924 |
| language | English |
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| physical | XII, 564 S. Ill., graph. Darst. 27 cm |
| publishDate | 2011 |
| publishDateSearch | 2011 |
| publishDateSort | 2011 |
| publisher | Springer |
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| series2 | Springer reference |
| spelling | Drug discovery and evaluation: methods in clinical pharmacology with 95 tables Hans Gerhard Vogel ... (eds.) Berlin [u.a.] Springer 2011 XII, 564 S. Ill., graph. Darst. 27 cm txt rdacontent n rdamedia nc rdacarrier Springer reference Literaturangaben Klinische Pharmakologie (DE-588)4073517-5 gnd rswk-swf Klinisches Experiment (DE-588)4164223-5 gnd rswk-swf Klinische Pharmakologie (DE-588)4073517-5 s Klinisches Experiment (DE-588)4164223-5 s DE-604 Vogel, H. Gerhard 1927- (DE-588)173094597 edt Erscheint auch als Online-Ausgabe Drug Discovery and Evaluation: Methods in Clinical Pharmacology DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024515351&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Drug discovery and evaluation: methods in clinical pharmacology with 95 tables Klinische Pharmakologie (DE-588)4073517-5 gnd Klinisches Experiment (DE-588)4164223-5 gnd |
| subject_GND | (DE-588)4073517-5 (DE-588)4164223-5 |
| title | Drug discovery and evaluation: methods in clinical pharmacology with 95 tables |
| title_auth | Drug discovery and evaluation: methods in clinical pharmacology with 95 tables |
| title_exact_search | Drug discovery and evaluation: methods in clinical pharmacology with 95 tables |
| title_full | Drug discovery and evaluation: methods in clinical pharmacology with 95 tables Hans Gerhard Vogel ... (eds.) |
| title_fullStr | Drug discovery and evaluation: methods in clinical pharmacology with 95 tables Hans Gerhard Vogel ... (eds.) |
| title_full_unstemmed | Drug discovery and evaluation: methods in clinical pharmacology with 95 tables Hans Gerhard Vogel ... (eds.) |
| title_short | Drug discovery and evaluation: methods in clinical pharmacology |
| title_sort | drug discovery and evaluation methods in clinical pharmacology with 95 tables |
| title_sub | with 95 tables |
| topic | Klinische Pharmakologie (DE-588)4073517-5 gnd Klinisches Experiment (DE-588)4164223-5 gnd |
| topic_facet | Klinische Pharmakologie Klinisches Experiment |
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