Human toxicology of chemical mixtures: toxic consequences beyond the impact of one-component product and environmental exposures
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier, William Andrew
2011
|
| Ausgabe: | 2. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | XV, 558 S. graph. Darst. |
| ISBN: | 9781437734638 |
Internformat
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| 100 | 1 | |a Zeliger, Harold I. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Human toxicology of chemical mixtures |b toxic consequences beyond the impact of one-component product and environmental exposures |c Harold I. Zeliger |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Amsterdam [u.a.] |b Elsevier, William Andrew |c 2011 | |
| 300 | |a XV, 558 S. |b graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 338 | |b nc |2 rdacarrier | ||
| 650 | 2 | |a Environmental Illness | |
| 650 | 2 | |a Hazardous Substances |a toxicity | |
| 650 | 2 | |a Environmental Pollutants |a toxicity | |
| 650 | 2 | |a Environmental Exposure | |
| 650 | 4 | |a Toxicological chemistry | |
| 650 | 4 | |a Environmental toxicology | |
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Datensatz im Suchindex
| _version_ | 1804148521955229696 |
|---|---|
| adam_text | Contents
Preface
to the Second Edition
ix
Preface to the First Edition
xi
List of Abbreviations
xiii
Part I Introduction to Chemical Toxicology of Mixtures
1
1
Introduction
3
2
Health Effects of Exposures to Chemical Mixtures
7
3
Absorption of Chemical Mixtures
15
4
Chemical Toxicology
21
Part II Exposures to Chemical Mixtures
43
5
Scope and Sources of Toxic Exposures
45
6
In
Utero
Exposure
49
7
Air Pollution
53
8
Water Pollution
65
9
Soil Pollution
97
10
Food
105
11
Chemicals In and Around the Home
129
12
Sick Building Syndrome
143
13
Industrial Exposure
159
14
Pesticides
173
15
Alcohol and Tobacco: Recreational Toxins
187
16
Electromagnetic Radiation and Toxic Exposure
205
Part III Mixture Effects on Body Systems
219
17
Respiratory System
221
18
Nervous System
251
19
Developmental Neurotoxicology
281
20
Autism: Effect of Maternal Exposure to Neurotoxic Chemicals
287
21
Attention Deficit Hyperactivity Disorder
299
22
Endocrine System
307
23
Toxic Infertility
323
Contents
24 Teratogens
341
25 Immune System
355
26 Chemical
Sensitivity:
Multiple Chemical
Sensitivity (MCS),
Chronic Fatigue Syndrome
(CFS), Fibromyalgia (FM),
Gulf War Syndrome
365
27
Skin
389
28 Musculoskeletal System
399
29
Cardiovascular
System
405
30
Liver
417
31
Kidneys
427
32
Cancer
433
33
Cancer Clusters
467
34
Nanotoxicology
479
35
Children
487
36
Childhood Cancer
499
37
Toxicology of Global Warming
507
Part IV Regulatory Requirements, Conclusions
521
38
Regulatory Requirements
523
39
Conclusions and Recommendations
531
Index
537
HUMAN
TOXICOLOGY
OF CHEMICAL MIXTURES
HAROLD I. ZELIGER
SECOND EDITION
A fhree-in-one foundational text that: comprehensively documents the known
effects of chemical mixtures on the human body; presents a plausible framework
for beginning to understand and predict their effects; and recommends how to limit
and regulate the release of mixtures info the environment.
•
Presents a theoretical framework for predicting the effects of chemico! mixtures for which
no specific data exists.
•
A quick and convenient source of hard to come by data on the rapidly developing
field of chemical mixtures.
•
New and updated material comprises over
30%
of this timely new edition. The second
edition has three new chapters; children s toxicology, Nanotoxicology and the toxicology
of global warming.
In this important reference work, Zeliger catalogs the known effects of chemical mixtures on the
human body and also proposes a framework for understanding and predicting their actions in
terms of lipophile ¡fat soluble)
/ hydrophile
(water soluble) interactions. The author s focus is
on illnesses thot ensue following exposures to mixtures of chemicals that cannot be attributed
to any one component of the mixture. In Part I, the mechanisms of chemical absorption at a
molecular and macromolecular level are explained, as well as the body s methods of defending
itself against xenobiotic intrusion. Part II examines the sources of the chemicals discussed, looking
at air and water pollution, indoor air environments, food additives, Pharmaceuticals, etc. Part
III, with numerous case studies, examines specific effects of particular mixtures on particular
body systems and organs and presents a theoretical framework for predicting what the effects of
uncharacterized mixtures might be. Part IV covers regulatory requirements and the need to adjust
recommended exposure levels for products containing mixtures and how to limit exposure to
mixtures in the products we use and on how to limit release of mixtures into the environment.
Providing brief summaries of each mixture and its effects, Zeliger provides a comprehensive
reference, a jumping off point for professional. Addressing many inadequately understood illnesses
and conditions such as asthma, infertility, cancer and other unexplained environmentally induced
diseases, it will also be of interest to emergency room physicians, internists and other health
professionals, environmental scientists, industrial
hygienists,
formulators
of chemical products,
and lawyers. A must for every college, university and research laboratory library. This book is a
recommended text for toxicology, medicinal chemistry and industrial hygiene courses.
|
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| ctrlnum | (OCoLC)760143987 (DE-599)HBZHT015682566 |
| discipline | Chemie / Pharmazie Medizin |
| edition | 2. ed. |
| format | Book |
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| id | DE-604.BV039659320 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T00:08:28Z |
| institution | BVB |
| isbn | 9781437734638 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-024508757 |
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| physical | XV, 558 S. graph. Darst. |
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| spelling | Zeliger, Harold I. Verfasser aut Human toxicology of chemical mixtures toxic consequences beyond the impact of one-component product and environmental exposures Harold I. Zeliger 2. ed. Amsterdam [u.a.] Elsevier, William Andrew 2011 XV, 558 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Environmental Illness Hazardous Substances toxicity Environmental Pollutants toxicity Environmental Exposure Toxicological chemistry Environmental toxicology Umwelttoxikologie (DE-588)4121813-9 gnd rswk-swf Umwelttoxikologie (DE-588)4121813-9 s DE-604 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024508757&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024508757&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Zeliger, Harold I. Human toxicology of chemical mixtures toxic consequences beyond the impact of one-component product and environmental exposures Environmental Illness Hazardous Substances toxicity Environmental Pollutants toxicity Environmental Exposure Toxicological chemistry Environmental toxicology Umwelttoxikologie (DE-588)4121813-9 gnd |
| subject_GND | (DE-588)4121813-9 |
| title | Human toxicology of chemical mixtures toxic consequences beyond the impact of one-component product and environmental exposures |
| title_auth | Human toxicology of chemical mixtures toxic consequences beyond the impact of one-component product and environmental exposures |
| title_exact_search | Human toxicology of chemical mixtures toxic consequences beyond the impact of one-component product and environmental exposures |
| title_full | Human toxicology of chemical mixtures toxic consequences beyond the impact of one-component product and environmental exposures Harold I. Zeliger |
| title_fullStr | Human toxicology of chemical mixtures toxic consequences beyond the impact of one-component product and environmental exposures Harold I. Zeliger |
| title_full_unstemmed | Human toxicology of chemical mixtures toxic consequences beyond the impact of one-component product and environmental exposures Harold I. Zeliger |
| title_short | Human toxicology of chemical mixtures |
| title_sort | human toxicology of chemical mixtures toxic consequences beyond the impact of one component product and environmental exposures |
| title_sub | toxic consequences beyond the impact of one-component product and environmental exposures |
| topic | Environmental Illness Hazardous Substances toxicity Environmental Pollutants toxicity Environmental Exposure Toxicological chemistry Environmental toxicology Umwelttoxikologie (DE-588)4121813-9 gnd |
| topic_facet | Environmental Illness Hazardous Substances toxicity Environmental Pollutants toxicity Environmental Exposure Toxicological chemistry Environmental toxicology Umwelttoxikologie |
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