The laboratory rabbit, guinea pig, hamster, and other rodents:
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
Amsterdam [u.a.]
Elsevier, Academic Press
2012
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Ausgabe: | 1. ed. |
Schriftenreihe: | American College of Laboratory Animal Medicine series
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Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XVII, 1268 S. Ill., graph. Darst. |
ISBN: | 9780123809209 |
Internformat
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Datensatz im Suchindex
_version_ | 1804148477285892096 |
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adam_text | Titel: The laboratory rabbit, guinea pig, hamster, and other rodents
Autor: Suckow, Mark A.
Jahr: 2012
Contents
Preface xiii
List of Contributors xv
List of Reviewers xix
4. Euthanasia and Necropsy
MIHAl GAÜEA-IURASCU AND SUZANNE CRAIG
I
Introduction 59
Clinical Biochemistry
Rabbit 70
Guinea Pig 76
Hamster 80
Other Rodents 85
Hematology 90
Rabbit 97
Guinea Pig 102
Hamster 104
Other Rodents 106
References 110
59
Introduction 117
Euthanasia 117
Necropsy 123
Pathology Considerations
References 136
134
GENERAL
1. Ethical Considerations and Regulatory Issues
MARILYN J. BROWN AND KATHLEEN L. SMILER
Introduction 3
Ethical Concepts 4
Ethical Challenges 14
Institutional Animal Welfare Oversight 20
Regulations and Non-regulatory Considerations 21
Conclusion 27
References 27
2. Anesthesia and Analgesia
PATRICK A. LESTER, RASHIDA M. MOORE,
KATHERINE A. SHUSTER, AND DANIEL D. MYERS
Pre-anesthetic Preparation 34
Controlled Substances 34
Pharmacology 35
Anesthesia Circuits 44
Anesthesia Monitoring and Support 46
Surgical Anesthesia 49
Post-operative Monitoring and Pain Assessment 50
References 53
3. Clinical Biochemistry and Hematology
IDA M. WASHINGTON AND GERALD VAN HOOSIER
5. Zoonoses and Occupational Health
DAVID W. BRAMMER
Introduction 142
Viral Diseases 142
Rickettsial Diseases 144
Chlamydial Diseases 146
Bacterial Diseases 146
Fungal Diseases 149
Cestode Infections 150
Arthropod Infections 150
Allergies 150
Prevention of Allergy and Zoonotic Disease 151
References 151
ÏI
RABBITS
6. The Domestic Rabbit, Oryctolagus Cuniculus:
Origins and History
KATHERINE A. NAFF AND SUZANNE CRAIG
Introduction and Background 157
Phylogeny and Taxonomy 158
Geographic Origins and Diversity 159
Domestication and Breed Development 160
Ecology and Conservation 161
References 162
7. Rabbit Genetics and Transgenic Models
NEIL D. CHRISTENSEN AND XUWEN PENG
Rabbit Genetics 165
Transgenic Rabbits 174
Conclusions 185
References 185
VI
CONTENTS
8. Anatomy, Physiology, and Behavior
JOANNE SOHN AND MARCELO A. COUTO
Introduction 195
External Features 196
Osteology 197
Oral Cavity 199
Abdominal Viscera 200
Urogenital System 203
Thoracic Viscera 207
Brain and Spinal Cord 208
Metabolism 211
Behavior 211
Acknowledgment 213
References 213
9. Rabbit Colony Management and Related
Health Concerns
ROBERT H. QUINN
Introduction 218
Laboratory Management 218
Breeding 229
Nutrition 232
Nutritionally Related Diseases 236
References 238
10. Basic Experimental Methods in the Rabbit
CYNTHIA A. PEKOW
Introduction 243
Handling and Restraint 244
Sampling Techniques 246
Compound Administration 250
Specialized Research Techniques 254
References 256
11. Polyclonal Antibody Production
Introduction 259
The Immunogen 260
Immunogen Dose 261
Route of Immunization
Immunization Schedule
Adjuvants 263
Summary 270
References 270
HAROLD F. STILLS
262
263
1.3. Bacterial Diseases
DAVID DELONG
Introduction 303
Pasteurellosis 303
Enterotoxemia 314
Tyzzer s Disease 318
Colibacillosis 321
Salmonellosis 326
Staphylococcosis 328
Treponematosis 331
Necrobacillosis 335
Listeriosis 337
Tuberculosis 339
Tularemia 341
Proliferative Enteropathy 343
Miscellaneous Bacterial Diseases 344
References 348
14- Viral Diseases
THEA BRABB AND RONALD F. DI GIACOMO
Introduction 365
DNA Virus Infections
RNA Virus Infections
References 401
368
386
15. Parasitic Diseases
STACY PRITT, KIMBERLEY COHEN, AND HEATHER SEDLACEK
Introduction 415
Protozoa 416
Arthropods 428
Helminths 435
References 443
16. Rabbit Neoplasia
PEGGY T. TINKEY, RAJESH K. UTHAMANTHIL, AND
STEVEN H. WEISBROTH
Introduction 448
Neoplasms of Oryctolagus cuniculus
Neoplasms of Sylvilagus 487
Neoplasms of Lepus 489
References 489
458
12. Toxicity and Safety Testing
DEBRA KIRCHNER AND SUSAN HENWOOD
Introduction 275
Toxicity Testing 276
Safety Testing 280
Metabolism and Toxicokinetics
Acknowledgments 296
References 296
294
17. Mycoses and Non-Infectious Diseases
KRISTIE BROCK, LAURA GALLAUGHER, VALERIE K. BERGDALL, AND
ROBERTC. DYSKO
Introduction 504
Mycotic Diseases 504
Non-Infectious Diseases 505
References 523
CONTENTS
Vil
18. The Rabbit as an Experimental Model
TANYA H. BURKHOLDER, GARRY LINTON, ROBERT F. HOYT, JR., AND
RICHARD YOUNG
Introduction 530
Cardiovascular Diseases 530
Ophthalmic Diseases 537
Central Nervous System Diseases 542
Respiratory Diseases 542
Urogenital Diseases 545
Gastrointestinal Diseases 546
Musculoskeletal Diseases 548
Multisystemic Diseases 550
Acknowledgments 552
References 552
III
GUINEA PIGS
19. Taxonomy and History
STACY PRITT
Introduction 563
Taxonomy and Geographical Distribution 564
Origin and Domestication 566
Genetics 568
References 572
20. Anatomy, Physiology, and Behavior
MAUREEN HARGADEN AND LAURA SINGER
Introduction 576
External Anatomy 576
Musculoskeletal System 578
Digestive System 581
Cardiovascular System 583
Pulmonary System 586
Genitourinary System 590
Nervous System 596
Special Senses 596
Behavior 598
References 599
21. Management, Husbandry, and Colony Health
VINCENT C. GRESHAM AND VICKY L. HAINES
Introduction 603
Handling 604
Housing 604
Reproduction and Breeding 611
Nutrition 612
Colony Health 614
Record Keeping 615
References 617
22. Basic Experimental Methods
RICHARD B. HUNEKE
Introduction 621
Handling and Restraint 621
Sampling Techniques 622
Compound Administration 624
Specialized Research Techniques 624
References 632
23. Infectious Diseases
THEA BRABB, DENISE NEWSOME, ANDREW BURICH, AND
MARTHA HANES
Introduction 638
Viral Diseases 638
Bacterial Infections 645
Fungal Infections 661
Protozoa Infections 665
Parasitic Infections 669
References 676
24. Non-Infectious Diseases
BRUCE H. WILLIAMS
Introduction 686
Cardiovascular System 686
Respiratory System 687
Gastrointestinal System 688
Urinary System 691
Endocrine System 692
Reproductive System 693
Musculoskeletal System 696
Integumentary System 698
Special Senses 700
Hematolymphatic System 700
Multisystemic Conditions 701
References 702
25. Guinea Pigs as Experimental Models
DOUGLAS K. TAYLOR AND VANESSA K LEE
Introduction 705
Models of Disease 706
References 728
IV
HAMSTERS
26. Taxonomy and History
GERALD D. SMITH
Taxonomy 747
Geographical Distribution
Origin and Domestication
Genetics 750
Acknowledgments 7 51
References 751
747
748
vi«
CONTENTS
27. Anatomy, Physiology, and Behavior
KATHLEEN A. MURRAY
Introduction 753
External Features 753
Musculoskeletal System 754
Digestive System 754
Circulatory System 756
Pulmonary System 757
Genitourinary System 757
Nervous System 760
Special Senses 761
Behavior 762
References 762
28. Management, Husbandry, and Colony Health
GUY B. MULDER
Introduction 765
Housing 765
Environmental Conditions 766
Nutrition 768
Breeding 770
Colony Health 771
Record Keeping 774
References 775
29. Biomedical Research Techniques
JERALD SILVERMAN
Introduction 779
General Non-Surgical Procedures
Injections and Intubations 783
Biological Specimen Collections
Other Surgical Procedures 789
References 793
780
786
30. Bacterial and Fungal Diseases
CRAIG S. FRISK
Introduction 798
Bacterial Diseases 798
Fungal Diseases 816
References 817
31. Viral Diseases
AMY CASSANO, SKYE RASMUSSEN, AND FELIX R. WOLF
Introduction 822
DNA Viruses 822
RNA Viruses 828
Miscellaneous Viruses 833
References 833
32. Parasitic Diseases
HOLLY N. BURR, LEE-RONN PALUCH, GORDON S. ROBLE, AND
NEIL S. LIPMAN
Introduction 839
Protozoa 840
Nematodes 847
Cestodes 854
Arthropods 857
References 863
33. Non-Infectious Diseases
BRIAN KAROLEWSKI, THOMAS W. MAYER, AND GAYE RUBLE
Introduction 867
Diseases Associated with Aging 867
Nutritional Disorders 871
Genetic, Traumatic, Environmental and Other Non-Infectious
Diseases 871
Neoplasms 872
References 872
34. The Experimental Use of Syrian Hamsters
HELEN VALENTINE, ERIN K. DAUGHERITY, BHUPINDER SINGH, AND
KIRK J. MAURER
Introduction 876
Cancer Research 876
Metabolic Diseases 879
Non-Cancerous Respiratory Diseases 883
Cardiovascular 885
Infectious Disease Research 887
Other Models 894
References 898
35. The Chinese or Striped-Back Hamster
WILLIAM P. FEENEY
Introduction 907
Biology 908
Care and Husbandry 909
Cytogenetics and Fetal Development 910
Diseases 910
Research Uses 913
Summary 918
References 919
36. The European Hamster
JUDY FENYK-MELODY
Taxonomy 923
History 923
Biology 924
Behavior 928
Diseases 929
Management, Husbandry, and Colony Health 930
Experimental Methodology 930
Use in Biomedical Research 930
References 931
37- Other Hamsters
BETH A. BAUER AND CYNTHIA BESCH-WILLIFORD
Introduction 935
Phodopus sungorus (Djungarian Hamster) 935
Mesocricetus branda (Turkish Hamster) 939
CONTENTS
IX
Cricetulus migratorius (Armenian Hamster) 941
Mesocricetus newtoni (Romanian Hamster) 942
References 943
CHINCHILLAS
, •?¦ Taxonomy and History
BRENT J. MARTIN
Introduction 949
Taxonomy 949
History 951
References 952
V), Anatomy, Physiology, and Behavior
LEANNE C. ALWORTH AND STEPHEN B. HARVEY
Introduction 955
External Features 955
Unique Biological Characteristics 957
Behavior 963
References 965
¦ Management, Husbandry, and
Colony Health
STEPHEN I. LEVIN, DIANA M.P. BERGER, AND TRACY L. GLUCKMAN
Introduction 967
Housing Systems 967
Environmental Conditions 969
Nutrition 970
Breeding 971
Colony Health 973
Record Keeping 973
References 975
Basic Experimental Methods
CHARLIE C. HSU, JELEEN A. BRISCOE, AND ANGELA B. KEFFER
Introduction 977
Handling and Restraint 978
Mechanical Methods 980
Sampling Techniques 982
Compound Administration 988
Specialized Research Techniques 990
References 990
Diseases and Veterinary Care
JOHN N. NORTON AND RANDALL P. REYNOLDS
Miscellaneous Conditions 1002
References 1006
Introduction 993
Infectious Diseases 994
Gastrointestinal and Metabolic Diseases
Traumatic Lesions 1001
Management-Related Disorders 1002
Neoplastic Diseases 1002
Chinchillas as Experimental Models
LISA MARTIN
Introduction 1009
Models Related to Aural Disease 1010
Models Related to Hearing Loss 1017
Future of Chinchilla Models 1026
References 1026
VI
1000
OTHER RODENTS
44. Degu
LESLEY A. COLBY, HOWARD G. RUSH, MEGAN M. MAHONEY AND
THERESA M. LEE
Introduction 1032
History and Taxonomy 1032
Anatomy, Physiology, and Behavior 1033
Management, Husbandry, and Colony Health 1038
Handling and Restraint 1043
Sampling Techniques 1044
Compound Administration 1044
Anesthesia and Analgesia 1044
Euthanasia and Necropsy 1046
Diseases 1046
The Degu as an Experimental Model 1047
References 1049
45. Naked Mole Rat
ROCHELLE BUFFENSTEIN, THOMAS PARK, MARTHA HANES, AND
JAMES E. ARTWOHL
History 1055
Taxonomy 1056
General Description 1056
Natural Habitat 1057
Behavior 1058
Reproductive Behavior 1059
General Physiology 1060
Anatomy and Physiology of Organ Systems 1061
Aging 1065
Husbandry 1066
Colony Health 1067
Use in Research 1069
References 1071
46. Deer Mice, White-Footed Mice, and their
Relatives
PETER C. SMITH, JODI A. CARLSON SCHOLZ, AND STEVEN R. WILSON
Introduction 1075
Biology 1078
Husbandry 1080
Captive Breeding 1081
X
CONTENTS
Diseases 1081
Anesthesia/Analgesia 1084
References 1085
47. Dormouse
JOHN P. LONG AND CHERI L. WEST
Introduction 1089
Taxonomy and History 1089
Anatomic Characteristics 1090
Husbandry 1090
Nutrition 1091
Housing 1091
Environmental Conditions 1092
Handling 1092
Breeding 1092
Diseases and Zoonoses 1092
Colony Health Monitoring 1092
Experimental Applications 1092
Biomethodology 1093
References 1093
48. Kangaroo Rat
DENISE M. NEWSOM AND GERALD L. VAN HOOSIER, JR.
Introduction 1095
Biology 1097
Diseases 1100
Use in Research 1101
Laboratory Care 1102
References 1103
49. Cotton Rat
JOSEPH F. CURLEE AND DALE M. COOPER
Introduction 1105
Biology 1106
Husbandry 1108
Diseases 1109
Experimental Methods 1110
Use in Research 1110
Acknowledgments 1111
References 1111
50. Pocket Gopher
M. SUSAN DEVRIES
Introduction 1115
Biology 1119
Diseases 1122
References 1123
51. White-Tailed Rat
BETH A. BAUER AND CYNTHIA L. BESCH-W1LLIFORD
Introduction 1125
Taxonomy, History, and Genetics 1125
Anatomy, Physiology, and Behavior 1126
Management, Husbandry, and Colony Health 1127
Basic Experimental Methods 1127
Diseases and Veterinary Care 1128
Experimental Models 1129
References 1129
52. Gerbils
MARGARET BATCHELDER, LYNN S. KELLER, MARY BALL SAUER,
AND WANDA L. WEST
Introduction 1132
Taxonomy and History 1132
Anatomy, Physiology, and Behavior 1133
Management, Husbandry, and Colony Health 1138
Basic Experimental Methods 1141
Veterinary Care and Diseases 1144
Gerbils as Experimental Models 1146
References 1149
53. Egyptian Fat-Tailed Jird
STEPHEN A. FELT, NANCY L. MERRILL, FADY I. GUIRGUIS, AND
HUSSEIN I. HUSSEIN
Introduction 1158
Anatomy, Physiology, and Behavior 1159
Management, Husbandry, and Colony Health 1160
Diseases 1164
Anesthesia/Analgesia, Euthanasia, and Necropsy 1167
Use in Research 1167
Basic Experimental Methods 1168
References 1169
54. Sand Rat
RONY KALMAN, EHUD ZIV, GALILA LAZAROVICI, AND
ELEAZAR SHAFRIR
Introduction 1171
Selection of Reliable Diets and Psammomys Lines for
Diabetes Research 1172
Metabolic Efficiency 1173
Morphology, Physiology, Breeding Performance, and
Husbandry 1176
The Basis of Diabetes in Psammomys 1179
The Relevance of Psammomys to Diabetes Research
The Genetic Basis of Psammomys Diabetes 1186
Worldwide Research Using Psammomys 1187
Complications of Diabetes in Psammomys 1187
Concluding Remarks 1188
References 1188
1185
VII
FORMULARY AND NORMATIVE
VALUES
55. Formulary
SEAN MAGUIRE AND C. TERRANCE HAWK
Introduction 1193
Rabbit (Oryctolagus cuniculus) 1194
CONTENTS
XI
Guinea Pig (Cavia porcellus) 1208
Hamster ( Mesocricetus auratus ) 1217
Degu (Octodon degus) 1222
Other Species 1224
References 1225
Hamsters 1234
Gerbils (Meriones unguiculatus)
Chinchillas (Chinchilla laniger)
Other rodents 1238
References 1243
1236
1237
56. Normative Values
JOLAINE M WILSON, DIANE J. GAERTNER, JAMES O. MARX, AND
F. CLAIRE HANKENSON
Rabbits (Oryctolagus cuniculus) 1232
Guinea pigs (Cavia porceüus) 1233
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title | The laboratory rabbit, guinea pig, hamster, and other rodents |
title_auth | The laboratory rabbit, guinea pig, hamster, and other rodents |
title_exact_search | The laboratory rabbit, guinea pig, hamster, and other rodents |
title_full | The laboratory rabbit, guinea pig, hamster, and other rodents ed. by Mark A. Suckow ... |
title_fullStr | The laboratory rabbit, guinea pig, hamster, and other rodents ed. by Mark A. Suckow ... |
title_full_unstemmed | The laboratory rabbit, guinea pig, hamster, and other rodents ed. by Mark A. Suckow ... |
title_short | The laboratory rabbit, guinea pig, hamster, and other rodents |
title_sort | the laboratory rabbit guinea pig hamster and other rodents |
topic | Versuchstiere (DE-588)4078861-1 gnd Nagetiere (DE-588)4171111-7 gnd |
topic_facet | Versuchstiere Nagetiere Aufsatzsammlung |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024478106&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT suckowmarka thelaboratoryrabbitguineapighamsterandotherrodents |