Proprotein convertases:
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Humana Press
2011
|
| Schriftenreihe: | Methods in molecular biology
768 |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XI, 367 S. Ill., graph. Darst. |
| ISBN: | 9781617792038 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804148436545568769 |
|---|---|
| adam_text | Titel: Proprotein convertases
Autor: Mbikay, Majambu
Jahr: 2011
Contents
Preface.......................................... v
Contributors....................................... ix
Section I: Reminiscences
1. On the Discovery of Precursor Processing..................... 3
Donald F. Steiner
2. The Prohormone Theory and the Proprotein Convertases: It Is All About
Serendipity..................................... 13
Michel Chrétien
Section II: Biochemistry and Cell Biology
3. The Proprotein Convertases, 20 Years Later.................... 23
Nabil G Seidah
4. Insights from Bacterial Subtilases into the Mechanisms of Intramolecular
Chaperone-Mediated Activation of Furin ..................... 59
Ujwal Shinde and Gary Thomas
5. The Novel Role of Cathepsin L for Neuropeptide Production Illustrated
by Research Strategies in Chemical Biology with Protease Gene Knockout
and Expression...................................107
Lydiane Funkelstein and Vivian Hook
6. In Vitro Assay for Protease Activity of Proprotein Convertase Subtilisin
Kexins (PCSKs): An Overall Review of Existing and New Methodologies.....127
Ajoy Basak, Andrew Chen, Swapan Majumdar, and Heather Palmer Smith
7. Inhibitor Screening of Proprotein Convertases Using Positional
Scanning Libraries.................................155
Iris Lindberg and Jon R. Appel
8. Analyses of PCSK9 Post-translational Modifications Using Time-of-Flight
Mass Spectrometry.................................167
Thilina Dewpura and Janice Mayne
Section III: Molecular Biology and Genetics
9. The Molecular Biology of Furin-Like Proprotein Convertases in Vascular
Remodelling....................................191
Philipp Stawowy and Kai Kappert
viii Contents
10. Identification of the Myosin Heavy Polypeptide 9 as a Downstream
Effector of the Proprotein Convertases in the Human Colon Carcinoma
HT-29 Cells....................................207
Nathalie Scamuffa, Peter Metrakos, Fabien Calvo, and Abdel-Majid Khatib
11. Regulation of 7B2 mRNA Translation: Dissecting the Role of Its
5 -Untranslated Region...............................217
Haidy Tadros, Günther Schmidt, Francine Sirois, and Majambu Mbikay
12. Analysis of Epigenetic Alterations to Proprotein Convertase Genes in Disease ... 231
TangXin Fu and Mark W. Nachtigal
13. Genetic and Functional Characterization of PCSK1................247
Hélène Choquet, Pieter Stijnen, and John W.M. Creemers
Section IV: Experimental Models
14. Prohormone Processing in Zebrafish........................257
Michael G. Morash, Kelly Soanes, and Tonnes Anini
15. Use of Zebrafish and Knockdown Technology to Define Proprotein
Convertase Activity.................................273
Babykumari P. Chitramuthu and Hugh PJ. Bennett
16. Characterization of Impaired Processing of Neuropeptides in the Brains
of Endoprotease Knockout Mice..........................297
Margery C. Beinfeld
17. Quantitative Peptidomics of Mice Lacking Peptide-Processing Enzymes......307
Jonathan Wardman and Lloyd D. Fricker
18. A Proteomic Protocol to Identify Physiological Substrates of Pro-protein
Convertases.....................................325
Guiying Nie and Andrew N. Stephens
19. Neurophenotyping Genetically Modified Mice for Social Behavior.........343
Ramona M. Rodriguiz, Jennifer S. Colvin, and William C. Wetsel
Index...........................................365
|
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| indexdate | 2024-07-10T00:07:06Z |
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| isbn | 9781617792038 |
| language | English |
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| publishDate | 2011 |
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| publisher | Humana Press |
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| series | Methods in molecular biology |
| series2 | Methods in molecular biology Springer protocols |
| spelling | Proprotein convertases ed. by Majambu Mbikay ... New York [u.a.] Humana Press 2011 XI, 367 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 768 Springer protocols Literaturangaben Mbikay, Majambu edt Methods in molecular biology 768 (DE-604)BV035362695 768 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024449300&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Proprotein convertases Methods in molecular biology |
| title | Proprotein convertases |
| title_auth | Proprotein convertases |
| title_exact_search | Proprotein convertases |
| title_full | Proprotein convertases ed. by Majambu Mbikay ... |
| title_fullStr | Proprotein convertases ed. by Majambu Mbikay ... |
| title_full_unstemmed | Proprotein convertases ed. by Majambu Mbikay ... |
| title_short | Proprotein convertases |
| title_sort | proprotein convertases |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024449300&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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