Verfügbarkeit: A history of diabetes in pregnancy

A history of diabetes in pregnancy: the impact of maternal diabetes on offspring prenatal development and survival

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Bibliographische Detailangaben
1. Verfasser:	Kalter, Harold (VerfasserIn)
Format:	Buch
Sprache:	English
Veröffentlicht:	Dordrecht [u.a.] Springer 2012
Schlagworte:	Schwangerschaft Diabetes
Online-Zugang:	Inhaltsverzeichnis
Beschreibung:	XII, 272 S.
ISBN:	9400715560 9789400715561

Internformat

MARC


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Datensatz im Suchindex

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adam_text	Contents 1 Introduction ................................................................................................. 1 2 The Framework .......................................................................................... 3 Early Childhood Death ................................................................................. 3 The Role of Diabetes .................................................................................... 4 Data Sources ................................................................................................. 5 Definition ...................................................................................................... 5 3 The Early Years .......................................................................................... 7 Maternal Mortality ........................................................................................ 7 Fertility .......................................................................................................... 8 4 Spontaneous Abortion ............................................................................... 11 Early Studies ................................................................................................. 12 Later Studies ................................................................................................. 12 Glycosylated Hemoglobin ............................................................................ 13 Glycosylated Hemoglobin and Spontaneous Abortion ............................ 13 Birmingham ............................................................................................. 14 Cincinnati ................................................................................................. 14 AMulticenterStudy ................................................................................. 15 Other Studies ........................................................................................... 16 Dose Response ......................................................................................... 16 An Interim Comment ............................................................................... 17 Tentative Conclusion ............................................................................... 17 Recent Studies ......................................................................................... 18 5 Perinatal Death ........................................................................................... 21 Definition and Classification ........................................................................ 21 Perinatal Death in Diabetes ........................................................................... 22 Gestational and Neonatal Age ................................................................. 23 Maternal Age ........................................................................................... 23 vi¡¡ Contents The Early Insulin Era ............................................................................... 24 The Two Forms of Diabetes .................................................................... 25 Facility Size ............................................................................................. 25 Stillbirth and Neonatal Death .................................................................. 26 Causes Generally ..................................................................................... 26 Causes in Pregnancy ................................................................................ 27 Macrosomia ............................................................................................. 28 Sex Hormone Imbalance ......................................................................... 29 Disease Severity ...................................................................................... 29 Other Alleged Relations ........................................................................... 30 Preventing Stillbirth ................................................................................. 31 The White Classification ......................................................................... 32 6 Prediabetes .................................................................................................. 35 Macrosomia in Prediabetic Pregnancy .......................................................... 36 Prediabetes Pregnancy Mortality .................................................................. 37 What Did it All Mean? .................................................................................. 38 Insidious Form of Diabetes ........................................................................... 38 A Summary ................................................................................................... 39 Prospective Approach ................................................................................... 39 Prediabetes and Congenital Malformation .................................................... 40 7 Gestational Diabetes .................................................................................. 43 What Is Gestational Diabetes? ...................................................................... 43 Early Questions ............................................................................................. 44 Maternal Age in Diabetic Pregnancy ............................................................ 44 Glycosuria ..................................................................................................... 45 Diabetogenicity of Pregnancy ....................................................................... 46 Blood Glucose Standards .............................................................................. 47 Vagaries of Blood Glucose Level ............................................................ 48 The Procedure and the Subjects ............................................................... 48 The Definition and its Mutations ............................................................. 50 The White Classification ......................................................................... 52 Pregnancy Outcome ................................................................................. 53 Did Gestational Diabetes Ever Cause Them? .......................................... 55 Gestational Diabetes and Congenital Malformation ............................... 56 Carbohydrate Metabolism and Pregnancy Outcome ............................... 57 Finale ....................................................................................................... 58 8 Pregestational Diabetes Type 2 ................................................................. 59 Type 2 Diabetes in Pima Indians .................................................................. 60 Type 2 Diabetes in other Groups ............................................................. 62 Type 2 and Gestational Diabetes ............................................................. 62 Type 2 Diabetes in Recent Years ............................................................. 63 Contents ix 9 Pregestational Diabetes Type 1 ............................................................. 67 White Classification.................................................................................. 68 Problems with the White System ........................................................ 68 The White System — Prepregnancy Based .......................................... 68 Insulin Dependent Diabetic Pregnancy ............................................... 70 White Class Variation .......................................................................... 71 10 Congenital Malformations — Questions ............................................... 73 What Are Congenital Malformations? ...................................................... 73 Cause and Frequency ................................................................................ 76 Death and Malformation ........................................................................... 77 11 Diabetes and Malformation ................................................................... 79 The Prevailing Opinion ............................................................................. 79 Diagnostic Problems ................................................................................. 80 Early Observations .................................................................................... 82 Malformations in Perinatal Death ............................................................. 84 Stillbirth vs Neonatal Death ...................................................................... 86 Diabetic vs Nondiabetic Mortality ............................................................ 86 Pathology Studies ...................................................................................... 87 Malformations in Surviving Infants .......................................................... 88 Minor Congenital Malformations ............................................................. 89 12 Malformations and Diabetes ................................................................. 91 A Specific Diabetic Embryopathy ............................................................. 91 Frequency of the Proposed Embryopathy ................................................. 92 Case Reports of the Proposed Association ................................................ 93 Retrospective Surveys of Caudal Dysplasia ............................................. 94 The Caudal Regression Syndrome ............................................................ 95 The Symmelia Syndrome .......................................................................... 96 Are Symmelia and Maternal Diabetes Associated? .................................. 97 Femoral Dysplasia and Diabetes ............................................................... 98 Facial and Femoral Abnormalitites ........................................................... 98 Are These Different Syndromes? .............................................................. 99 Other Malformations ................................................................................. 100 Conclusion ................................................................................................ 101 13 Diabetes Center Studies ......................................................................... 103 The Joslin Diabetes Center ....................................................................... 103 Other American Studies ............................................................................ 105 Cincinnati Studies ..................................................................................... 106 London Studies ......................................................................................... 107 Edinburgh Studies ..................................................................................... 108 Birmingham Studies .................................................................................. 109 Northern Ireland Studies ........................................................................... Ill x Contents Republic of Ireland Studies ....................................................................... 114 Denmark Studies ....................................................................................... H6 The Control Group .............................................................................. 116 The Outcome ....................................................................................... 117 The Aftermath ..................................................................................... 118 Finland Studies .......................................................................................... 120 Birmingham Hospital Study ..................................................................... 121 Johns Hopkins Study ................................................................................. 123 Critique ..................................................................................................... 123 14 Broad-scale Studies ................................................................................ 127 The Kučera Analysis ................................................................................. 127 The Neave Analysis .................................................................................. 128 The Malformations .................................................................................... 129 Perinatal Death Questions ......................................................................... 130 Race Considerations .................................................................................. 130 Research Biases ......................................................................................... 131 Multicenter Studies ................................................................................... 132 Sweden Studies ......................................................................................... 132 Large Studies ............................................................................................. 133 The Collaborative Perinatal Study ............................................................ 133 United Kingdom Study ............................................................................. 135 National Institute of Child Health Study .................................................. 136 Recent Studies ........................................................................................... 137 Diabetes Control and Complications Trial ................................................ 137 Denmark Studies ....................................................................................... 138 France Studies ........................................................................................... 139 15 Population-Based Studies ...................................................................... 141 Cohort Studies ........................................................................................... 142 Birth Certificate Studies ...................................................................... 142 Swedish Birth Registers ...................................................................... 143 Washington State Birth Register ......................................................... 144 Norwegian Birth Register .................................................................... 146 Australian Birth Registers ................................................................... 147 Hesse Birth Register ............................................................................ 148 Maine Birth Register ........................................................................... 148 Iceland Birth Register .......................................................................... 149 English Birth Registers ........................................................................ 149 Case-Control Studies ................................................................................ 150 Finland Study ...................................................................................... 150 Japan Study ......................................................................................... 151 Other Reports ...................................................................................... 151 Atlanta Study ....................................................................................... 151 Baltimore-Washington Infant Study .................................................... 153 Contents x¡ Heart Defect Studies in Sweden .......................................................... 154 CDC Congenital Renal Disease Study ................................................ 155 Miscellaneous Studies ......................................................................... 155 National Birth Defects Prevention Study ............................................ 156 Nova Scotia Study ............................................................................... 157 A Multi-center Study ........................................................................... 157 16 Specific Congenital Malformations ...................................................... 159 Caudal Dysplasia ...................................................................................... 159 Reports of Caudal Abnormalities ........................................................ 161 Central Nervous System Malformations ................................................... 162 Neural Tube Defects in Diabetic Pregnancy ....................................... 163 Perinatal Death .................................................................................... 164 Cardiovascular Malformations .................................................................. 165 Ventricular Šeptal Defects ................................................................... 166 Heart Defects in Perinatal Death ......................................................... 166 Heart Defects in Survivors .................................................................. 167 Heart Defects and Diabetes ................................................................. 167 Heart Defects in Diabetic Perinatal Death .......................................... 168 Cardiovascular Malformations in Survivors ....................................... 168 Prenatal Diagnosis ............................................................................... 170 17 Preventing Malformations .................................................................... 171 Hyperglycemia and Congenital Malformations ........................................ 171 Preconception Control and Malformation ................................................. 172 Copenhagen Study ............................................................................... 172 Edinburgh Study .................................................................................. 173 Karlsburg Study ................................................................................... 174 National Institutes of Health Study ..................................................... 174 Other Preconception Control Studies .................................................. 176 Temporal Trends .................................................................................. 178 A Matter of Puzzlement ....................................................................... 179 18 Prenatal and Follow-up Studies ............................................................ 181 Fetal Growth Delay ................................................................................... 181 Fetal Detection of Malformations ............................................................. 182 Follow-up of Children ............................................................................... 182 Congenital Malformations ........................................................................ 183 Height and Weight ..................................................................................... 184 Neurological Development and Intelligence ............................................. 185 A Comment ............................................................................................... 186 19 Diabetic Pregnancy in Animals I ......................................................... 189 Experimentally Induced Diabetes ............................................................. 189 Alloxan ...................................................................................................... 190 xii Contents Rats ........................................................................................................... 190 Mice .......................................................................................................... 191 Streptozotocin ........................................................................................... 192 Malformation vs Developmental Delay.................................................... 193 Teratological Mechanism .......................................................................... 194 Rat Stock Studies ...................................................................................... 195 Nutrition and Diabetes .............................................................................. 196 20 Diabetic Pregnancy in Animals Π ......................................................... 197 Spontaneous Diabetes ............................................................................... 197 Mouse Genes ............................................................................................. 197 The NOD Mouse ................................................................................. 197 The BB Rat .......................................................................................... 198 Chinese Hamster ................................................................................. 199 Other Species ............................................................................................ 200 Malformations — Direct vs Indirect Origin .......................................... 201 Malformations — Pre- or Postimplantation Origin ............................... 201 Fetal Growth Retardation .................................................................... 202 Missing Lower Vertebral Elements ..................................................... 203 Omphalocele ........................................................................................ 203 Conclusion ................................................................................................ 204 21 Is Diabetes Teratogenic? ........................................................................ 207 Introduction ............................................................................................... 207 Diabetes and Malformations ..................................................................... 208 The Principles of Teratology ..................................................................... 209 Diabetes and Teratological Principles ....................................................... 210 Teratological Specificity ........................................................................... 211 Dose-Response Relation .......................................................................... 211 A Summary of Sorts .................................................................................. 212 Bibliography ................................................................................................... 215 Index ................................................................................................................ 269
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spelling	Kalter, Harold Verfasser aut A history of diabetes in pregnancy the impact of maternal diabetes on offspring prenatal development and survival Harold Kalter Dordrecht [u.a.] Springer 2012 XII, 272 S. txt rdacontent n rdamedia nc rdacarrier Schwangerschaft (DE-588)4053724-9 gnd rswk-swf Diabetes (DE-588)4512641-0 gnd rswk-swf Diabetes (DE-588)4512641-0 s Schwangerschaft (DE-588)4053724-9 s DE-604 Erscheint auch als Online-Ausgabe 978-94-007-1557-8 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024182292&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Kalter, Harold A history of diabetes in pregnancy the impact of maternal diabetes on offspring prenatal development and survival Schwangerschaft (DE-588)4053724-9 gnd Diabetes (DE-588)4512641-0 gnd
subject_GND	(DE-588)4053724-9 (DE-588)4512641-0
title	A history of diabetes in pregnancy the impact of maternal diabetes on offspring prenatal development and survival
title_auth	A history of diabetes in pregnancy the impact of maternal diabetes on offspring prenatal development and survival
title_exact_search	A history of diabetes in pregnancy the impact of maternal diabetes on offspring prenatal development and survival
title_full	A history of diabetes in pregnancy the impact of maternal diabetes on offspring prenatal development and survival Harold Kalter
title_fullStr	A history of diabetes in pregnancy the impact of maternal diabetes on offspring prenatal development and survival Harold Kalter
title_full_unstemmed	A history of diabetes in pregnancy the impact of maternal diabetes on offspring prenatal development and survival Harold Kalter
title_short	A history of diabetes in pregnancy
title_sort	a history of diabetes in pregnancy the impact of maternal diabetes on offspring prenatal development and survival
title_sub	the impact of maternal diabetes on offspring prenatal development and survival
topic	Schwangerschaft (DE-588)4053724-9 gnd Diabetes (DE-588)4512641-0 gnd
topic_facet	Schwangerschaft Diabetes
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024182292&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
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