Enzyme kinetics and mechanisms:
Gespeichert in:
1. Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Dordrecht [u.a.]
Kluwer Academic Publ.
2010
|
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis Klappentext |
Beschreibung: | Literaturangaben |
Beschreibung: | XIII, 227 S. graph. Darst. |
ISBN: | 9789048160655 |
Internformat
MARC
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Datensatz im Suchindex
_version_ | 1804145741889798144 |
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adam_text | Vil
TABLE OF CONTENTS
Dedication
v
Table of Contents
vii
Preface
ix
Introduction
xi
1.
Introduction to Steady-State Kinetics
1
2.
The Generation of Experimental Data
7
3.
Methods for Model Evaluation
14
4.
Derivation of Mathematical Models
27
5.
Effects of Substrate Concentration
44
6.
Effects of Analog Inhibitors
66
7.
Effects of Product Inhibitors
89
8.
Effects of Substrate Inhibition
106
9.
Slow and Tight Inhibition
122
10.
The Thermodynamics of Initial Velocity
147
11.
Effects of
pH 164
12.
Effects of
Isotopie
Substitution
184
13.
Effects of Other Reaction Conditions
206
Index
223
Enzyme
Kinetics and Mechanisms
Kenneth B. Taylor
Enzyme Kinetics and Mechanisms takes the reader through the experimental
techniques and the logic by which the mechanisms of enzyme-catalyzed reactions can
be elucidated by the results of steady-state kinetics and related experiments. It is
meant to make these investigations both satisfying and effective. In distinction to
other available descriptions, the descriptions in Enzyme Kinetics and Mechanisms are
limited to the more commonly utilized and useful models and techniques. The logic
relating the chemical models to the mathematical models and the logic of relating the
mathematical
mexíeis
to data is presented in rather concise text, figures and equations.
The development of mathematical models from chemical models is done by a unique
algorithm thai is both simple and quick, and the same concepts are utilized to develop
models lor the effects of a variety of reaction conditions on the initial velocity. In
addition, the various relationships of data, mathematical models and chemical models
is illustrated with examples from the scientific literature.
Enzyme Kinetics and Mechanisms is intended for research workers, graduate
students, post doctoral associates, and faculty in biochemistry and molecular biology
who are interested in the techniques and logic by which mechanisms of enzyme-
catalyzed reactions can be elucidated by investigations of steady-state kinetic
experiments.
|
any_adam_object | 1 |
author | Taylor, Kenneth B. 1950- |
author_GND | (DE-588)170556360 |
author_facet | Taylor, Kenneth B. 1950- |
author_role | aut |
author_sort | Taylor, Kenneth B. 1950- |
author_variant | k b t kb kbt |
building | Verbundindex |
bvnumber | BV037433857 |
classification_rvk | WD 5050 |
ctrlnum | (OCoLC)760112869 (DE-599)BVBBV037433857 |
discipline | Biologie |
format | Book |
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id | DE-604.BV037433857 |
illustrated | Illustrated |
indexdate | 2024-07-09T23:24:17Z |
institution | BVB |
isbn | 9789048160655 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-022585889 |
oclc_num | 760112869 |
open_access_boolean | |
owner | DE-11 DE-703 |
owner_facet | DE-11 DE-703 |
physical | XIII, 227 S. graph. Darst. |
publishDate | 2010 |
publishDateSearch | 2010 |
publishDateSort | 2010 |
publisher | Kluwer Academic Publ. |
record_format | marc |
spelling | Taylor, Kenneth B. 1950- Verfasser (DE-588)170556360 aut Enzyme kinetics and mechanisms by Kenneth B. Taylor Dordrecht [u.a.] Kluwer Academic Publ. 2010 XIII, 227 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Enzymkinetik (DE-588)4133166-7 gnd rswk-swf Enzymstoffwechsel (DE-588)4129185-2 gnd rswk-swf Enzymkinetik (DE-588)4133166-7 s DE-604 Enzymstoffwechsel (DE-588)4129185-2 s Digitalisierung UB Bayreuth application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022585889&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Bayreuth application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022585889&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
spellingShingle | Taylor, Kenneth B. 1950- Enzyme kinetics and mechanisms Enzymkinetik (DE-588)4133166-7 gnd Enzymstoffwechsel (DE-588)4129185-2 gnd |
subject_GND | (DE-588)4133166-7 (DE-588)4129185-2 |
title | Enzyme kinetics and mechanisms |
title_auth | Enzyme kinetics and mechanisms |
title_exact_search | Enzyme kinetics and mechanisms |
title_full | Enzyme kinetics and mechanisms by Kenneth B. Taylor |
title_fullStr | Enzyme kinetics and mechanisms by Kenneth B. Taylor |
title_full_unstemmed | Enzyme kinetics and mechanisms by Kenneth B. Taylor |
title_short | Enzyme kinetics and mechanisms |
title_sort | enzyme kinetics and mechanisms |
topic | Enzymkinetik (DE-588)4133166-7 gnd Enzymstoffwechsel (DE-588)4129185-2 gnd |
topic_facet | Enzymkinetik Enzymstoffwechsel |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022585889&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022585889&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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