Biologic therapy for inflammatory bowel diseases:
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Bremen ; London ; Boston
UNI-MED-Verl.
2010
|
| Ausgabe: | 1. ed. |
| Schriftenreihe: | UNI-MED science
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | 78 S. graph. Darst. 25 cm |
| ISBN: | 9783837412529 9781848151659 |
Internformat
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| 245 | 1 | 0 | |a Biologic therapy for inflammatory bowel diseases |c [Daniel C. Baumgart. In collab. with Gert Van Assche ...] |
| 250 | |a 1. ed. | ||
| 264 | 1 | |a Bremen ; London ; Boston |b UNI-MED-Verl. |c 2010 | |
| 300 | |a 78 S. |b graph. Darst. |c 25 cm | ||
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| 338 | |b nc |2 rdacarrier | ||
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Datensatz im Suchindex
| _version_ | 1804143791428337664 |
|---|---|
| adam_text | IMAGE 1
CONTENTS
[1. I CONVENTIONAL THERAPY OF INFLAMMATORY BOWEL DISEASE 12
1.1. S-AMINOSALICYLICADD (S-ASA) 12
1.2. CORTICOSTEROIDS 12
1.3. BUDESONIDE 13
1.4. ANTIBIOTICS 14
1.5. AZATHIOPRINE/OE-MERCAPTOPURINE (6-MP) 14
1.6. METHOTREXATE 14
1.7. CYCLOSPORINE 15
1.8. TACROLIMUS (FK506) 15
1.9. SURGICAL OPTIONS 15
[2J BIOLOGIC THERAPY OF INFLAMMATORY BOWEL DISEASE 18
2.1. ANTI-TNF THERAPY FOR LUMINAL CROHN S DISEASE 18
2.1.1. INFLIXIMAB 18
2.1.1.1. POOLED EVIDENCE FOR EFFICACY TO MAINTAIN REMISSION 19
2.1.1.2. OPTIMAL LONG-TERM TREATMENT SCHEDULES 19
2.1.1.3. CAN ANTI-TNF THERAPY EVER BE STOPPED? 19
2.1.2. ADALIMUMAB 21
2.1.2.1. PHARMACODYNAMICS 21
2.1.2.2. PHARMACOKINETICS 22
2.1.2.3. CLINICAL EFFICACY 22
2.1.2.4. CLASSIC 1 22
2.1.2.5. CLASSIC 2 23
2.1.2.6. CHARM 23
2.1.2.7. GAIN 26
2.1.2.8. OTHER STUDIES 27
2.1.3. CERTOLIZUMAB 29
2.1.3.1. EFFICACY OF CERTOLIZUMAB PEGOL IN CROHN S DISEASE 29
2.1.3.2. SAFETY OF CERTOLIZUMAB PEGOL 31
2.2. ANTI-TNF THERAPY FOR FISTULIZING CROHN S DISEASE 32
2.2.1. INFLIXIMAB 32
2.2.1.1. TREATMENT OF FISTULAS WITH INFLIXIMAB 32
2.2.2. ADALIMUMAB 35
2.2.2.1. DATA FROM CHARM 35
2.2.2.2. OTHER STUDIES 36
2.3. ANTI-TNF THERAPY FOR ULCERATIVE COLITIS 37
2.3.1. INFLIXIMAB 37
2.3.1.1. THE EARLY NON-CONTROLLED EXPERIENCE WITH INFLIXIMAB 37
2.3.1.2. RANDOMIZED CONTROLLED TRIALS WITH INFLIXIMAB 37
2.3.1.3. STANDARD-TREATMENT CONTROLLED TRIALS WITH NFLIXIMAB 39
2.3.1.4. COCHRANE META-ANALYSIS ON NFLIXIMAB FOR INDUCTION OF REMISSION
IN ULCERATIVE COLITIS 39
2.3.1.5. OPEN-LABEL EXPERIENCES 39
2.3.1.6. CONSENSUS GUIDELINES 40
BIBLIOGRAFISCHE INFORMATIONEN HTTP://D-NB.INFO/100940833X
DIGITALISIERT DURCH
IMAGE 2
CONTENTS 9
2.4. ANTI-ADHESION MOLECULE THERAPY FOR CROHN S DISEASE AND ULCERATIVE
COLITIS 41
2.4.1. LEUKOCYTE-ENDOTHELIAL CELL INTERACTIONS 41
2.4.2. ADHESION MOLECULES INVOLVED IN LEUKOCYTE-ENDOTHELIAL CELL
INTERACTIONS 42 2.4.3. ADHESION MOLECULES IN HUMAN IBD 45
2.4.4. ADHESION MOLECULES AS TARGETS FOR THERAPEUTIC INTERVENTION 46
2.4.5. NATALIZUMAB 49
2.4.6. BLOCKADE OF A*SS 7 - MADCAM-1 INTERACTIONS 52
[57] FERTILITY, PREGNANCY AND NURSING AND BIOLOGIC THERAPY 58
3.1. FERTILITY 58
3.2. SAFETY OF BIOLOGIES DURING PREGNANCY 58
3.3. ANTI-TNFA THERAPIES 59
3.3.1. BREASTFEEDING AND ANTI-TNFA 60
3.3.2. THE EFFECTS OF IN UTERO EXPOSURE TO ANTI-TNFA 61
| 4. J RISKS AND COMPLICATIONS OF BIOLOGIC THERAPY 64
4.1. WHERE DO RISK DATA COME FROM? 64
4.2. RISKS OF ANTI-TNF AGENTS 64
4.2.1. INFECTIONS 65
4.2.2. DEMYELINATING DISORDERS 66
4.2.3. HEART FAILURE 66
4.2.4. ANTIBODY FORMATION 66
4.2.5. ANTI-TNFS AND CANCER 67
4.3. IS COMBINATION THERAPY MORE RISKY? 68
4.4. NATALIZUMAB 68
| 5. ] PEDIATRIE ASPECTS OF BIOLOGIC THERAPY 74
5.1. EFFICACY OF BIOLOGIC AGENTS IN PEDIATRIE PATIENTS 74
5.2. BIOLOGIC THERAPY AND GROWTH 75
5.3. SAFETY CONCERNS FOR PEDIATRIE PATIENTS 75
INDEX 78
|
| any_adam_object | 1 |
| author2 | Baumgart, Daniel C. |
| author2_role | edt |
| author2_variant | d c b dc dcb |
| author_facet | Baumgart, Daniel C. |
| building | Verbundindex |
| bvnumber | BV037202207 |
| ctrlnum | (OCoLC)700052995 (DE-599)DNB100940833X |
| dewey-full | 616.34406 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.34406 |
| dewey-search | 616.34406 |
| dewey-sort | 3616.34406 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 1. ed. |
| format | Book |
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| id | DE-604.BV037202207 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T22:53:16Z |
| institution | BVB |
| isbn | 9783837412529 9781848151659 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-021116427 |
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| publishDate | 2010 |
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| series2 | UNI-MED science |
| spelling | Biologic therapy for inflammatory bowel diseases [Daniel C. Baumgart. In collab. with Gert Van Assche ...] 1. ed. Bremen ; London ; Boston UNI-MED-Verl. 2010 78 S. graph. Darst. 25 cm txt rdacontent n rdamedia nc rdacarrier UNI-MED science Literaturangaben Crohn-Krankheit (DE-588)4026539-0 gnd rswk-swf Biologische Medizin (DE-588)4126895-7 gnd rswk-swf Colitis ulcerosa (DE-588)4070065-3 gnd rswk-swf Therapie (DE-588)4059798-2 gnd rswk-swf Crohn-Krankheit (DE-588)4026539-0 s Colitis ulcerosa (DE-588)4070065-3 s Therapie (DE-588)4059798-2 s Biologische Medizin (DE-588)4126895-7 s DE-604 Baumgart, Daniel C. edt DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=021116427&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Biologic therapy for inflammatory bowel diseases Crohn-Krankheit (DE-588)4026539-0 gnd Biologische Medizin (DE-588)4126895-7 gnd Colitis ulcerosa (DE-588)4070065-3 gnd Therapie (DE-588)4059798-2 gnd |
| subject_GND | (DE-588)4026539-0 (DE-588)4126895-7 (DE-588)4070065-3 (DE-588)4059798-2 |
| title | Biologic therapy for inflammatory bowel diseases |
| title_auth | Biologic therapy for inflammatory bowel diseases |
| title_exact_search | Biologic therapy for inflammatory bowel diseases |
| title_full | Biologic therapy for inflammatory bowel diseases [Daniel C. Baumgart. In collab. with Gert Van Assche ...] |
| title_fullStr | Biologic therapy for inflammatory bowel diseases [Daniel C. Baumgart. In collab. with Gert Van Assche ...] |
| title_full_unstemmed | Biologic therapy for inflammatory bowel diseases [Daniel C. Baumgart. In collab. with Gert Van Assche ...] |
| title_short | Biologic therapy for inflammatory bowel diseases |
| title_sort | biologic therapy for inflammatory bowel diseases |
| topic | Crohn-Krankheit (DE-588)4026539-0 gnd Biologische Medizin (DE-588)4126895-7 gnd Colitis ulcerosa (DE-588)4070065-3 gnd Therapie (DE-588)4059798-2 gnd |
| topic_facet | Crohn-Krankheit Biologische Medizin Colitis ulcerosa Therapie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=021116427&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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