RNA polymerases as molecular motors:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Cambridge
Royal Society of Chemistry
2009
|
| Schriftenreihe: | RSC Biomolecular sciences
v. 16 |
| Schlagworte: | |
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| Beschreibung: | This book, written by expert scientists in the field, analyses how diverse fields of scientific research interact on a specific example - RNA polymerases, The cell can be viewed as a 'collection of protein machines' and understanding these molecular machines requires sophisticated cooperation between cell biologists, geneticists, enzymologists, crystallographers, chemists and physicists. To observe these machines in action, researchers have developed entirely new methodologies for the detection and the nanomanipulation of single molecules. This book, written by expert scientists in the field, analyses how these diverse fields of research interact on a specific example - RNA polymerase. The book concentrates on RNA polymerases because they play a central role among all the other machines operating in the cell and are the target of a wide range of regulatory mechanisms. They have also been the subject of spectacular advances in their structural understanding in recent years, as testified by the attribution of the Nobel prize in chemistry in 2006 to Roger Kornberg. The book focuses on two aspects of the transcription cycle that have been more intensively studied thanks to this increased scientific cooperation - the recognition of the promoter by the enzyme, and the achievement of consecutive translocation steps during elongation of the RNA product. Each of these two topics is introduced by an overview, and is then presented by worldwide experts in the field, taking the viewpoint of their speciality. The overview chapters focus on the mechanism-structure interface and the structure-machine interface while the individual chapters within each section concentrate more specifically on particular processes-kinetic analysis, single-molecule spectroscopy, and termination of transcription, amongst others. Specific attention has been paid to the newcomers in the field, with ++ careful descriptions of new emerging techniques and the constitution of an atlas of three-dimensional pictures of the enzymes involved. For more than thirty years, the study of RNA polymerases has benefited from intense cooperation between the scientific partners involved in the various fields listed above. It is hoped that a collection of essays from outstanding scientists on this subject will catalyse the convergence of scientific efforts in this field, as well as contribute to better teaching at advanced levels in Universities |
| Beschreibung: | 1 Online-Ressource (330 p.) 59 b&w, ill |
| ISBN: | 1847559980 9781847559982 |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV037195559 |
| illustrated | Not Illustrated |
| indexdate | 2024-08-01T11:43:57Z |
| institution | BVB |
| isbn | 1847559980 9781847559982 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-021109921 |
| oclc_num | 873742497 |
| open_access_boolean | |
| owner | DE-12 DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-Aug4 DE-1046 DE-1047 DE-1102 DE-1050 DE-859 DE-M347 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-210 DE-2070s DE-634 DE-526 DE-860 DE-70 DE-B768 |
| owner_facet | DE-12 DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-Aug4 DE-1046 DE-1047 DE-1102 DE-1050 DE-859 DE-M347 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-210 DE-2070s DE-634 DE-526 DE-860 DE-70 DE-B768 |
| physical | 1 Online-Ressource (330 p.) 59 b&w, ill |
| psigel | ZDB-1-RSE |
| publishDate | 2009 |
| publishDateSearch | 2009 |
| publishDateSort | 2009 |
| publisher | Royal Society of Chemistry |
| record_format | marc |
| series2 | RSC Biomolecular sciences |
| spellingShingle | RNA polymerases as molecular motors DNS-abhängige-RNS-Polymerasen (DE-588)4273322-4 gnd |
| subject_GND | (DE-588)4273322-4 (DE-588)4143413-4 |
| title | RNA polymerases as molecular motors |
| title_auth | RNA polymerases as molecular motors |
| title_exact_search | RNA polymerases as molecular motors |
| title_full | RNA polymerases as molecular motors Edited by Henri Buc, Terence Strick ; Series edited by Stephen Neidle [et al.] ; Contributions by Bianca Sclavi [et al.] |
| title_fullStr | RNA polymerases as molecular motors Edited by Henri Buc, Terence Strick ; Series edited by Stephen Neidle [et al.] ; Contributions by Bianca Sclavi [et al.] |
| title_full_unstemmed | RNA polymerases as molecular motors Edited by Henri Buc, Terence Strick ; Series edited by Stephen Neidle [et al.] ; Contributions by Bianca Sclavi [et al.] |
| title_short | RNA polymerases as molecular motors |
| title_sort | rna polymerases as molecular motors |
| topic | DNS-abhängige-RNS-Polymerasen (DE-588)4273322-4 gnd |
| topic_facet | DNS-abhängige-RNS-Polymerasen Aufsatzsammlung |
| url | http://www.rsc.org/Publishing/eBooks/2009/9780854041343.asp |
| work_keys_str_mv | AT buchenri rnapolymerasesasmolecularmotors AT strickterence rnapolymerasesasmolecularmotors AT neidlestephen rnapolymerasesasmolecularmotors AT cloremarius rnapolymerasesasmolecularmotors AT lilleydavidmj rnapolymerasesasmolecularmotors |