Concepts in toxicology: Explanatory dictionary of key terms
Gespeichert in:
Bibliographische Detailangaben
1. Verfasser: Duffus, John H. (VerfasserIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Cambridge Royal Society of Chemistry 2009
Online-Zugang:BHS01
BSB01
BTU01
BTW01
DMM01
FAN01
FAW01
FAW02
FHA01
FHD01
FHM01
FHN01
FHR01
FKE01
FLA01
FWS01
FWS02
HWR01
LCO01
SAB01
SAM01
SBG01
SBR01
SND01
TUM01
UBA01
UBG01
UBM01
UBR01
UBT01
UBW01
UER01
UPA01
Volltext
Beschreibung:This one-stop reference is for those who need to understand key toxicological concepts in the light of increasing chemical regulations, Toxicology has never been more important. Advances in chemistry and technology offering improvements in the quality of human life become ever more rapid, bringing with them the potential for new toxicity hazards. This has led to legislation requiring toxicity testing and risk assessment for all chemicals and their uses. The new REACH (Risk Evaluation and Authorization of Chemicals) Regulation has profound economic consequences because, without official authorization, a chemical cannot be marketed. This book explains, in depth, the ideas underlying current advances in toxicology and its application in regulating and ensuring the safe use of chemicals. Sometimes old ideas have become assumptions that have become embedded in related laws and regulation, even though the thinking of toxicologists has moved on in line with developments in science. This leads to confusion in public understanding that the book should dispel. There are also fundamental ideas in toxicology that are not well understood concerning the concepts of hazard and risk and even about what constitutes a chemical. For many people the word 'chemical' describes manmade substances only. In fact, it is correctly applied to all substances that exist, from pure elements to the most complex biological molecules in food and medicines. This is further complicated by the complex distinction between the descriptors, 'toxic' and 'nontoxic'. Developments in epigenetics are revolutionizing our understanding of mutagenicity and carcinogenicity. Improved understanding of apoptosis and necrosis leads to improved interpretation of potentially toxic effects at the cellular level. The recently defined term 'chemical speciation' is driving more targeted research on the toxicity of inorgan++
ic chemicals. This book explains the concepts implied by key toxicological terms using diagrams to illustrate the relationships between them. It is an essential aid to understanding the new demands from regulators of risk assessment and to the implementation of appropriate risk management
Beschreibung:1 Online-Ressource (250 p.)
ISBN:1847559751
9781847559753