High-field EPR spectroscopy on proteins and their model systems: Characterization of transient paramagnetic states
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cambridge
Royal Society of Chemistry
2008
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| Schlagworte: | |
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| Beschreibung: | A comprehensive overview of experimental techniques in high-field EPR spectroscopy and their applications in biology and biochemistry, Understanding the major factors determining the specificity of transmembrane transfer processes in proteins is currently a hot topic in molecular bio-science. Advanced electron paramagnetic resonance (EPR) at high magnetic fields is a powerful technique for characterizing the transient states of proteins in action on biologically relevant time scales. This book offers a comprehensive overview of experimental techniques in, and paradigmatic examples of, the application of high-field EPR spectroscopy in biology and chemistry. It focuses on the use of the technique in conjunction with site-specific mutation strategies and advanced quantum-chemical computation methods to reveal protein structure and dynamics. This yields new insights into biological processes at the atomic and molecular level. The theoretical and instrumental background of high-field EPR is described and examples of paradigmatic protein systems, such as photosynthesis, are discussed in the light of recent investigations. Aspects of structure-dynamics-function relations that are revealed by studying site-specific mutants are highlighted, thereby combining high-field EPR with genetic engineering techniques. The information obtained complements that obtained from protein crystallography, solid-state NMR, infrared and optical spectroscopy. The book documents both background knowledge and results of the latest research in the field. Unique features include comparisons of information content of EPR, ENDOR, Triple resonance, ESEEM and PELDOR taken at different microwave frequencies and magnetic fields. Coherent treatment of the subject by the leading Berlin high-field EPR laboratory covers the theoretical background as well as state-of-art research both in terms of instrumentation and application to biological systems. Finally, the book provides an outlook to future developments and references for further reading. High-Field EPR Spectroscopy on Proteins in Action is essential reading for scientists, professionals, academics and post graduate students working in this field |
| Beschreibung: | 1 Online-Ressource (392 p.) 115 b&w, ill |
| ISBN: | 1847559271 9781847559272 |
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| 500 | |a instrumentation and application to biological systems. Finally, the book provides an outlook to future developments and references for further reading. High-Field EPR Spectroscopy on Proteins in Action is essential reading for scientists, professionals, academics and post graduate students working in this field | ||
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Datensatz im Suchindex
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| author | Mobius, Klaus G. |
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| discipline | Chemie / Pharmazie Biologie |
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| id | DE-604.BV037195491 |
| illustrated | Not Illustrated |
| indexdate | 2024-08-01T11:43:57Z |
| institution | BVB |
| isbn | 1847559271 9781847559272 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-021109853 |
| oclc_num | 837811152 |
| open_access_boolean | |
| owner | DE-12 DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-Aug4 DE-1046 DE-1047 DE-1102 DE-1050 DE-859 DE-M347 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-210 DE-2070s DE-634 DE-526 DE-860 DE-70 DE-B768 |
| owner_facet | DE-12 DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-Aug4 DE-1046 DE-1047 DE-1102 DE-1050 DE-859 DE-M347 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-210 DE-2070s DE-634 DE-526 DE-860 DE-70 DE-B768 |
| physical | 1 Online-Ressource (392 p.) 115 b&w, ill |
| psigel | ZDB-1-RSE |
| publishDate | 2008 |
| publishDateSearch | 2008 |
| publishDateSort | 2008 |
| publisher | Royal Society of Chemistry |
| record_format | marc |
| spellingShingle | Mobius, Klaus G. High-field EPR spectroscopy on proteins and their model systems Characterization of transient paramagnetic states Electron paramagnetic resonance spectroscopy Proteins Analysis Electron Spin Resonance Spectroscopy Proteins analysis Proteine (DE-588)4076388-2 gnd Elektronenspinresonanzspektroskopie (DE-588)4151888-3 gnd |
| subject_GND | (DE-588)4076388-2 (DE-588)4151888-3 |
| title | High-field EPR spectroscopy on proteins and their model systems Characterization of transient paramagnetic states |
| title_auth | High-field EPR spectroscopy on proteins and their model systems Characterization of transient paramagnetic states |
| title_exact_search | High-field EPR spectroscopy on proteins and their model systems Characterization of transient paramagnetic states |
| title_full | High-field EPR spectroscopy on proteins and their model systems Characterization of transient paramagnetic states Klaus Mobius, Anton Savitsky |
| title_fullStr | High-field EPR spectroscopy on proteins and their model systems Characterization of transient paramagnetic states Klaus Mobius, Anton Savitsky |
| title_full_unstemmed | High-field EPR spectroscopy on proteins and their model systems Characterization of transient paramagnetic states Klaus Mobius, Anton Savitsky |
| title_short | High-field EPR spectroscopy on proteins and their model systems |
| title_sort | high field epr spectroscopy on proteins and their model systems characterization of transient paramagnetic states |
| title_sub | Characterization of transient paramagnetic states |
| topic | Electron paramagnetic resonance spectroscopy Proteins Analysis Electron Spin Resonance Spectroscopy Proteins analysis Proteine (DE-588)4076388-2 gnd Elektronenspinresonanzspektroskopie (DE-588)4151888-3 gnd |
| topic_facet | Electron paramagnetic resonance spectroscopy Proteins Analysis Electron Spin Resonance Spectroscopy Proteins analysis Proteine Elektronenspinresonanzspektroskopie |
| url | http://www.rsc.org/publishing/ebooks/2008/9780854043682.asp |
| work_keys_str_mv | AT mobiusklausg highfieldeprspectroscopyonproteinsandtheirmodelsystemscharacterizationoftransientparamagneticstates AT savitskyanton highfieldeprspectroscopyonproteinsandtheirmodelsystemscharacterizationoftransientparamagneticstates |