Studies on renal disorders:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Humana Press [u.a.]
2011
|
| Schriftenreihe: | Oxidative stress in applied basic research and clinical practice
|
| Schlagworte: | |
| Online-Zugang: | Inhaltstext Inhaltsverzeichnis Klappentext |
| Beschreibung: | XVIII, 783 S. Ill., graph. Darst. |
| ISBN: | 9781607618560 |
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Datensatz im Suchindex
| _version_ | 1805095251196510208 |
|---|---|
| adam_text |
Oxidative
Stress
in Applied
Basic Research and Clinical Practice
Donald Armstrong, Series Editor
Toshio Miyata
·
Kai-Uwe Eckardt
■
Masaomi Nangaku Editors
Studies on Renal Disorders
Conditions such as oxidative stress and hypoxia, which have a generalized impact on
the oxygen metabolism, have been implicated in the genesis of kidney disease. This
means that deepening our understanding ot the pathobiology of oxygen metabolism
in such diseases could be a fruitful path towards tangible clinical benefits. Studies in
Renal Disorder collects reviews from leading researchers and clinical scientists working
in exactly this field, providing an overview of the latest advances.
The causal role of impaired oxygen metabolism in kidney disease has numerous clinical
implications. It affects our understanding of the therapeutic benefits accruing from anti-
hypertensive agents, the way we control hyperglycemia/hyperinsulinemia and hyperli-
pidemia, and our use of dietary approaches to the correction of obesity. The defensive
mechanisms against oxidative stress, such as the Nrfi-Keapi system, and hypoxia, such
as the PHDHIF system, have recently been explored in various cells, including kidney
cells. These mechanisms include intracellular sensors for oxidative stress and hypoxia.
This means that novel approaches targeting these sensors may offer clinical benefits in
kidney disease in which oxidative stress and/or hypoxia is a final, common pathway.
Contents
Part I Oxidative Stress
1
Oxidative Stress Injury in Glomerular Mesangium
. 3
Josef Pfeilschifter and
Karl-Friedrich Beck
2
Transition Metals and Other Forms of Oxidative
Protein Damage in Renal Disease
. 25
Vincent M. Monnier,
Ina Nemet,
David
R.
Sell,
and Miriam F. Weiss
3
Cyclooxygenase in the Kidney and Oxidative Stress
. 51
Raymond C. Harris
4
Renin-Angiotensin System in the Kidney and Oxidative Stress:
Local Renin-Angiotensin-AIdosterone System
and NADPH Oxidase-Dependent Oxidative Stress
in the Kidney
. 71
Hideyasu Kiyomoto, Hiroyuki Kobori, and Akira Nishiyama
5
Thiamine in Diabetic Renal Disease: Dietary Insufficiency,
Renal Washout,
Antistress Gene
Response,
Therapeutic Supplements, Risk Predictor,
and Link to Genetic Susceptibility
. 93
Paul J. Thornalley and Naila
Rabbani
6
Novel Members of the Globin Family and Their Function
Against Oxidative Stress
. 105
Hiroshi Nishi and Masaomi Nangaku
Contents
Part II Clinical Aspects of Oxidative Stress in the Kidney
7
Hypertension
. 121
Bernardo Rodriguez-Iturbe and Nosratola D. Vaziri
8
Uric Acid and Oxidative Stress
. 143
Yuri Y. Sautin, Witcha Imaram, Kyung
Mee Kim,
Alexander Angerhofer, George Henderson, and Richard Johnson
9
Reactive Oxygen and Nitrogen Species, Oxidative
and Nitrosative Stress, and Their Role in
the Pathogenesis of Acute Kidney Injury
. 161
Eisei Noiri, Francesco Addabbo, and Michael S. Goligorsky
10
Oxidative Stress in the Kidney: Proximal Tubule Disorders
. 179
Sara Terryn and Olivier Devuyst
11
Iron Metabolism and Oxidative Stress
. 205
Abolfazl Zarjou,
József
Balla,
György
Balla,
and Anupam Agarwal
12
Hypoxia, Oxidative Stress, and the Pathophysiology
of Contrast-Media-Induced Nephropathy
. 229
Samuel
N.
Heyman, Seymour Rosen, Mogher Khamaisi,
Jean-Marc Odee, and Christian Rosenberger
13
Cardiovascular Complications in Renal Failure:
Implications of Advanced Glycation End Products
and Their Receptor RAGE
. 257
Hidenori Koyama and Yoshiki Nishizawa
14
Infection and the Kidney
. 293
Chin-Wei Yang
15
Oxidative/Carbonyl Stress in the Renal Circulation
and Cardiovascular Renal Injury
. 305
Takefumi Mori, Toshio Miyata, and Sadayoshi
Ito
Part III Current Therapy Targeting Oxidative tress
16
The Renin Angiotensin System
. 323
Josephine M. Forbes and Mark E. Cooper
Contents ix
17 Oxidative
Stress
in
Kidney Injury: Peroxisome
Proliferator-Activated Receptor-7
Agonists Are in Control
. 337
Li-Jun
Ma and
Agnes B.
Fogo
18
Current Therapy Targeting Oxidative Stress: Statin
. 351
Ravi Nistala and Adam Whaley-Connell
19
N-Acetylcysteine in Kidney Disease
. 367
Giancarlo Marenzi, Erminio Sisillo, and Antonio L. Bartorelli
20
Advanced Glycation End Products Inhibitor
. 389
Takashi Dan, Charles van Ypersele
de Strihou,
and Toshio Miyata
Part IV Hypoxia
21
Involvement of Hypoxia-Inducible Factor
1
in Physiological
and Pathological Responses to Continuous and
Intermittent Hypoxia: Role of Reactive Oxygen Species
. 409
Gregg L.
Semenza
22
Regulation of Oxygen Homeostasis by Prolyl
Hydroxylase Domains
. 419
Kotaro Takeda
and Guo-Hua Fong
23
Oxygen-Dependent Regulation of Erythropoiesis
. 437
Volker
H. Haase
24
Intricate Link between Hypoxia and Oxidative Stress
in Chronic Kidney Disease
. 465
Tetsuhiro Tanaka
25
RNA
Interference and the Regulation of Renal
Gene Expression in Hypoxia
. 479
Carsten
С.
Scholz,
Colin
R.
Lenihan, Cormac
T.
Taylor,
and
Ulrike
Bruning
Part V Hypoxia Pathology in Renal Disorders
26
Cardio-Renai
Connection: The Role of Hypoxia
and Oxidative Stress
. 499
Carsten Willam,
Tilmann Ditting, Roland Veelken,
and Johannes Jacobi
x
Contents
27
Hypoxia-Inducible Factors
in
Acute Kidney Injury: From
Pathophysiology to a Novel Approach of Organ Protection
. 535
Wanja M.
Bernhardt, Carsten Willam,
and Kai-Uwe Eckardt
28
Hypoxia in Chronic Kidney Disease: The Final Common
Pathway to End Stage Renal Disease
. 545
Masaomi Nangaku
29
Oxidative Stress and Hypoxia in the Pathogenesis
of Diabetic Nephropathy
. 559
Fredrik
Palm,
Lina
Nordquist, Christopher S. Wilcox,
and Peter Hansell
30
Estimation of Kidney
Oxygénation
by Blood
Oxygénation
Level Dependent Magnetic Resonance Imaging
. 587
Lu-Ping Li and Pottumarthi V.
Prasad
31
Anemia and Progression of Chronic Kidney Disease
. 611
Danilo
Fliser and Ferdinand H. Bahlmann
Part VI Novel therapeutic approaches against oxidative
stress and hypoxia
32
Novel Therapeutic Approaches Against Oxidative Stress
and Hypoxia, Targeting Intracellular Sensor Molecules
for Oxygen and Oxidative Stress
. 633
Toshio Miyata and Charles van Ypersele
de
Strihou
33
Endoplasmic Reticulum Stress as a Target of Therapy
Against Oxidative Stress and Hypoxia
. 657
Reiko Inagi
34
Stem Cell Therapy Against Oxidative Stress and Hypoxia
. 673
Takashi Yokoo and Motoko Yanagita
Name Index
. 689
Subject Index
. 779 |
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| spelling | Studies on renal disorders Toshio Miyata ..., ed. New York, NY Humana Press [u.a.] 2011 XVIII, 783 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Oxidative stress in applied basic research and clinical practice Nierenfunktionsstörung (DE-588)4216345-6 gnd rswk-swf Nierenfunktionsstörung (DE-588)4216345-6 s DE-604 Miyata, Toshio 1938- Sonstige (DE-588)121279952 oth Erscheint auch als Online-Ausgabe 978-1-60761-857-7 text/html http://deposit.dnb.de/cgi-bin/dokserv?id=3480668&prov=M&dok_var=1&dok_ext=htm Inhaltstext Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=021083390&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=021083390&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
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| title | Studies on renal disorders |
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| title_full | Studies on renal disorders Toshio Miyata ..., ed. |
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